I. Design and Synthesis of Cysteine Protease Inhibitors. II. Total Synthesis of (-)-bafilomycin A1 III. Studies Directed Towards the Total Synthesis of Apoptolidin

I. Design and Synthesis of Cysteine Protease Inhibitors. II. Total Synthesis of (-)-bafilomycin A1 III. Studies Directed Towards the Total Synthesis of Apoptolidin PDF Author: Karl A. Scheidt
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Category :
Languages : en
Pages : 652

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Studies on the Total Synthesis of Tetrafibricin ; Synthesis of Conformationally Constrained Cysteine Protease Inhibitors ; Palladium Catalyzed Synthesis of N-aryl-2-benzylindolines Via Tandem Arylation of 2-allylaniline(s)

Studies on the Total Synthesis of Tetrafibricin ; Synthesis of Conformationally Constrained Cysteine Protease Inhibitors ; Palladium Catalyzed Synthesis of N-aryl-2-benzylindolines Via Tandem Arylation of 2-allylaniline(s) PDF Author: Ricardo Lira
Publisher: ProQuest
ISBN: 9780549723523
Category : Cysteine proteinases
Languages : en
Pages : 466

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Detailed in the following thesis are: (1) the diastereoselective synthesis of the C(1)-C(19) fragment of tetrafibricin, (2) a convenient, direct method for the synthesis 1,5-syn-(E)-diols from aldehyde precursors, and (3) application of this method to the completion of the C(23)-C(40) fragment of tetrafibricin (this transformation involves an initial allylboration generating syn-[beta]-alkoxyallylstannane intermediates, followed by an allylstannation step), (4) The synthesis of the complete C(1)-C(40) fragment via our double allylboration strategy and efforts towards the total synthesis of tetrafibricin, (5) the development of a convenient method to access syn-[beta]-hydroxyallylsilanes via a Lewis acid-promoted [gamma]-silylallylboration of alipathic aldehydes with new (Z)-[gamma]-silylallylboronate reagents, (6) The synthesis of a new class of conformationally constrained cysteine protease inhibitors via ring closing metathesis step, (7) a palladium-catalyzed synthesis of N-aryl-2-benzylindolines via a tandem arylation of 2-allylanilines, (this transformation leads to the formation of two C-N bonds and one C-C bond in a one-pot process, and high selectivity is observed for the sequential installation of two different aryl groups).

American Doctoral Dissertations

American Doctoral Dissertations PDF Author:
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Category : Dissertation abstracts
Languages : en
Pages : 848

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Selected Studies in Asymmetric Synthesis

Selected Studies in Asymmetric Synthesis PDF Author: William John Smith (III.)
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Category :
Languages : en
Pages : 542

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Studies Towards the Total Synthesis of Bafilomycin A1

Studies Towards the Total Synthesis of Bafilomycin A1 PDF Author: Iain Simpson
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Languages : en
Pages :

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Dissertation Abstracts International

Dissertation Abstracts International PDF Author:
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Category : Dissertations, Academic
Languages : en
Pages : 992

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I. Studies Toward the Total Synthesis of Scytophycin C ; II. Optimized Synthesis of Vinyl Sulfonamide Inhibitors of the Cysteine Protease Cruzain

I. Studies Toward the Total Synthesis of Scytophycin C ; II. Optimized Synthesis of Vinyl Sulfonamide Inhibitors of the Cysteine Protease Cruzain PDF Author: Beth A. Knapp-Reed
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Category :
Languages : en
Pages : 474

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Modeling, Design and Synthesis of Parasitic Cysteine Protease Inhibitors

Modeling, Design and Synthesis of Parasitic Cysteine Protease Inhibitors PDF Author: Yogesh A. Sabnis
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Languages : en
Pages : 414

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Studies Directed Towards the Synthesis of Bafilomycin A1

Studies Directed Towards the Synthesis of Bafilomycin A1 PDF Author: A. P. Butler
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Category :
Languages : en
Pages :

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Total Synthesis of Bafilomycin A1

Total Synthesis of Bafilomycin A1 PDF Author: Florian Karl Kleinbeck
Publisher:
ISBN:
Category :
Languages : en
Pages : 266

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