Hypersensitivity Diagnosis. Development of an Automatic and Quantitative IgE Concentration Detection Algorithm PDF Download
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Author: Satish Thapaliya
Publisher: GRIN Verlag
ISBN: 3346121380
Category : Medical
Languages : en
Pages : 82
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Book Description
Master's Thesis from the year 2014 in the subject Medicine - Biomedical Engineering, Peking University, language: English, abstract: Allergic diseases are seen to affect a large number of people around the world every year. The proper diagnosis of allergic disease is an important factor to maintain the good health condition of a general population. Although there are several techniques available for the diagnosis of allergic disease, most of the methods fail to cover all of the criteria to make it acceptable. This study introduces general methods of allergy diagnosis which are in practice in current scenario and different image processing techniques that can be incorporated into it to make the process even easier. In this study ELISA technique is proposed to fulfill all the basic criteria like sensitivity, accuracy and most importantly cost effectiveness. ELISA is an immunoassay that involves the detection of Immunoglobulin type E commonly referred as IgE. An enzyme linked anti-human globulin is made to react with IgE, if present in the patient's serum which will produce the colored product when the substrate of the enzyme is added. Depending upon the concentration of the colored product, the concentration of IgE is determined. The experiment condition like wet condition and plastic container can significantly change the detected color of the allergen card and hence the result value. This proves that the system environment indeed affects calculated IgE concentration. In order to reduce this negative effect, we need to find an effective image feature which is little influenced by system environment. The content of this study mainly focuses on different color models of the color images that can be used in image processing technology which are further utilized to define its relationship with IgE concentration or the severity of the disease. Involving the features of both binary and color image models it gives the better comparison of the different image features in different color models. These image features ware tested and result curves were produced that describes the relationship between IgE concentration and image feature. Based on the experimental findings the new diagnostic image feature was introduced. The experiments were done to test the accuracy of the proposed diagnostic image feature which is cheap, sensitive and can detect the IgE concentration quantitatively.
Author: Satish Thapaliya
Publisher: GRIN Verlag
ISBN: 3346121380
Category : Medical
Languages : en
Pages : 82
Get Book Here
Book Description
Master's Thesis from the year 2014 in the subject Medicine - Biomedical Engineering, Peking University, language: English, abstract: Allergic diseases are seen to affect a large number of people around the world every year. The proper diagnosis of allergic disease is an important factor to maintain the good health condition of a general population. Although there are several techniques available for the diagnosis of allergic disease, most of the methods fail to cover all of the criteria to make it acceptable. This study introduces general methods of allergy diagnosis which are in practice in current scenario and different image processing techniques that can be incorporated into it to make the process even easier. In this study ELISA technique is proposed to fulfill all the basic criteria like sensitivity, accuracy and most importantly cost effectiveness. ELISA is an immunoassay that involves the detection of Immunoglobulin type E commonly referred as IgE. An enzyme linked anti-human globulin is made to react with IgE, if present in the patient's serum which will produce the colored product when the substrate of the enzyme is added. Depending upon the concentration of the colored product, the concentration of IgE is determined. The experiment condition like wet condition and plastic container can significantly change the detected color of the allergen card and hence the result value. This proves that the system environment indeed affects calculated IgE concentration. In order to reduce this negative effect, we need to find an effective image feature which is little influenced by system environment. The content of this study mainly focuses on different color models of the color images that can be used in image processing technology which are further utilized to define its relationship with IgE concentration or the severity of the disease. Involving the features of both binary and color image models it gives the better comparison of the different image features in different color models. These image features ware tested and result curves were produced that describes the relationship between IgE concentration and image feature. Based on the experimental findings the new diagnostic image feature was introduced. The experiments were done to test the accuracy of the proposed diagnostic image feature which is cheap, sensitive and can detect the IgE concentration quantitatively.
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1296
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Book Description
Author: E. N. Clare Mills
Publisher: John Wiley & Sons
ISBN: 0470995165
Category : Technology & Engineering
Languages : en
Pages : 238
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Book Description
Plant Food Allergens is concerned with a paradox of immense, potentially life-threatening significance to about 1 in 100 adults and 1 in 10 children. The paradox is that certain nutritious proteins from wholesome foods can act as if the were harmful, sometimes deadly poisons, to these people who possess an allergy to them. In order to study the complex problems of food allergy a EU funded network, called PROTALL was set up, bringing together a wide range of clinicians and scientists. This important book is largely based on the outcome of its investigations. Written by over 30 acknowledged experts and carefully edited by Dr Clare Mills and Professor Peter Shewry, themselves well known internationally; this important work covers all major aspects of the subject. Commencing with introductory chapters, the comprehensive contents of Plant Food Allergens includes details of the major allergens including: plant lipid transfer proteins, the 2S albumin proteins, the cereal á-amylase/trypsin family, latex and plant chitinases, profilins, bet v 1-homologous allergens and plant seed globulins. The book concludes with important chapters on the assessment of the allergenicity of novel and GM foods, and the monitoring of and technological effects on allergenicity of proteins in the food industry. Plant Food Allergens is an essential purchase for a wide range of scientists and clinicians including plant and agricultural scientists, chemists, allergy specialists, food scientists and technologists, pharmacologists, physiologists and nutritionists. Libraries in all research establishments and universities researching and teaching these subjects will need copies of this important book on their shelves Dr Clare Mills is based at The Institute of Food Research, Norwich, UK. Professor Peter Shewry is based at Rothamsted Research, Harpenden, UK.
Author: Mikhail Sofiev
Publisher: Springer Science & Business Media
ISBN: 9400748817
Category : Medical
Languages : en
Pages : 256
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Book Description
This is the first book to summarize all aspects of allergenic pollen: production, atmospheric distribution, and health impacts, as well as the means of monitoring and forecasting these phenomena. Based on a four-year effort by a large group of leading European scientists, this book highlights the new developments in research on allergenic pollen, including the modelling prospects and effects of climate change. The multidisciplinary team of authors offers insights into the latest technology of detection of pollen and its allergenic properties, forecasting methods, and the influence of allergenic pollen on the population. The comprehensive coverage in this book makes it an indispensible volume for anyone dealing with allergenic pollen worldwide. Readers involved in environmental health, aerobiology, medicine, and plant science will find this book of interest.
Author: Barbara J. Bain
Publisher: Elsevier Health Sciences
ISBN: 0702069256
Category : Medical
Languages : en
Pages : 599
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Book Description
For more than 65 years, this best-selling text by Drs. Barbara J. Bain, Imelda Bates, and Mike A. Laffan has been the worldwide standard in laboratory haematology. The 12th Edition of Dacie and Lewis Practical Haematology continues the tradition of excellence with thorough coverage of all of the techniques used in the investigation of patients with blood disorders, including the latest technologies as well as traditional manual methods of measurement. You'll find expert discussions of the principles of each test, possible causes of error, and the interpretation and clinical significance of the findings. - A unique section on haematology in under-resourced laboratories. - Ideal as a laboratory reference or as a comprehensive exam study tool. - diagnosis, molecular testing, blood transfusion- and much more. - Complete coverage of the latest advances in the field. - An expanded section on coagulation now covers testing for new anticoagulants and includes clinical applications of the tests.
Author: Simon Flanagan
Publisher: Elsevier
ISBN: 1782420215
Category : Technology & Engineering
Languages : en
Pages : 453
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Book Description
Allergens in food and their detection, management and elimination constitute a key issue for food manufacturers, especially in terms of safety. This book reviews current and emerging technologies for detecting and reducing allergens, as well as issues such as traceability, regulation and consumer attitudes. Following an introductory chapter by a distinguished expert, part one covers allergen management throughout the food chain. Part two details current and emerging methods of allergen detection in food, and part three covers methods for reducing and eliminating allergens in food. Finally, part four focuses on the control and detection of individual food allergens and the risks each one presents in food manufacture. - Reviews current and emerging technologies for detecting and reducing allergens, as well as issues such as traceability, regulation and consumer attitudes - Covers allergen management throughout the food chain and reviews current and emerging methods of allergen detection - Examines methods for reducing and eliminating allergens in food and provides a detailed overview of the control and detection of individual food allergens
Author: Peter Luppa
Publisher: Springer
ISBN: 3662544970
Category : Medical
Languages : en
Pages : 451
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Book Description
The underlying technology and the range of test parameters available are evolving rapidly. The primary advantage of POCT is the convenience of performing the test close to the patient and the speed at which test results can be obtained, compared to sending a sample to a laboratory and waiting for results to be returned. Thus, a series of clinical applications are possible that can shorten the time for clinical decision-making about additional testing or therapy, as delays are no longer caused by preparation of clinical samples, transport, and central laboratory analysis. Tests in a POC format can now be found for many medical disciplines including endocrinology/diabetes, cardiology, nephrology, critical care, fertility, hematology/coagulation, infectious disease and microbiology, and general health screening. Point-of-care testing (POCT) enables health care personnel to perform clinical laboratory testing near the patient. The idea of conventional and POCT laboratory services presiding within a hospital seems contradictory; yet, they are, in fact, complementary: together POCT and central laboratory are important for the optimal functioning of diagnostic processes. They complement each other, provided that a dedicated POCT coordination integrates the quality assurance of POCT into the overall quality management system of the central laboratory. The motivation of the third edition of the POCT book from Luppa/Junker, which is now also available in English, is to explore and describe clinically relevant analytical techniques, organizational concepts for application and future perspectives of POCT. From descriptions of the opportunities that POCT can provide to the limitations that clinician’s must be cautioned about, this book provides an overview of the many aspects that challenge those who choose to implement POCT. Technologies, clinical applications, networking issues and quality regulations are described as well as a survey of future technologies that are on the future horizon. The editors have spent considerable efforts to update the book in general and to highlight the latest developments, e.g., novel POCT applications of nucleic acid testing for the rapid identification of infectious agents. Of particular note is also that a cross-country comparison of POCT quality rules is being described by a team of international experts in this field.
Author: Umile Gianfranco Spizzirri
Publisher: John Wiley & Sons
ISBN: 111916057X
Category : Technology & Engineering
Languages : en
Pages : 359
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Book Description
Food safety and quality are key objectives for food scientists and industries all over the world. To achieve this goal, several analytical techniques (based on both destructive detection and nondestructive detection) have been proposed to fit the government regulations. The book aims to cover all the analytical aspects of the food quality and safety assessment. For this purpose, the volume describes the most relevant techniques employed for the determination of the major food components (e.g. protein, polysaccharides, lipds, vitamins, etc.), with peculiar attention to the recent development in the field. Furthermore, the evaluation of the risk associated with food consumption is performed by exploring the recent advances in the detection of the key food contaminants (e.g. biogenic amines, pesticides, toxins, etc.). Chapters tackle such subject as: GMO Analysis Methods in Food Current Analytical Techniques for the Analysis of Food Lipids Analytical Methods for the Analysis of Sweeteners in Food Analytical Methods for Pesticides Detection in Foodstuffs Food and Viral Contamination Application of Biosensors to Food Analysis
Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 2068
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Book Description
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.
Author: Alan H. B. Wu
Publisher: Elsevier Health Sciences
ISBN: 1437719872
Category : Medical
Languages : en
Pages : 1857
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Book Description
This new edition of Norbert Tietz's classic handbook presents information on common tests as well as rare and highly specialized tests and procedures - including a summary of the utility and merit of each test. Biological variables that may affect test results are discussed, and a focus is placed on reference ranges, diagnostic information, clinical interpretation of laboratory data, interferences, and specimen types. New and updated content has been added in all areas, with over 100 new tests added. - Tests are divided into 8 main sections and arranged alphabetically. - Each test includes necessary information such as test name (or disorder) and method, specimens and special requirements, reference ranges, chemical interferences and in vivo effects, kinetic values, diagnostic information, factors influencing drug disposition, and clinical comments and remarks. - The most current and relevant tests are included; outdated tests have been eliminated. - Test index (with extensive cross references) and disease index provide the reader with an easy way to find necessary information - Four new sections in key areas (Preanalytical, Flow Cytometry, Pharmacogenomics, and Allergy) make this edition current and useful. - New editor Alan Wu, who specializes in Clinical Chemistry and Toxicology, brings a wealth of experience and expertise to this edition. - The Molecular Diagnostics section has been greatly expanded due to the increased prevalence of new molecular techniques being used in laboratories. - References are now found after each test, rather than at the end of each section, for easier access.
