Hormone Action and Signal Transduction in Endocrine Physiology and Disease PDF Download
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Author: László Hunyady
Publisher: Frontiers Media SA
ISBN: 2889661008
Category : Medical
Languages : en
Pages : 134
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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author: László Hunyady
Publisher: Frontiers Media SA
ISBN: 2889661008
Category : Medical
Languages : en
Pages : 134
Get Book Here
Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author: Vincent Goffin
Publisher: Springer Science & Business Media
ISBN: 1475736002
Category : Medical
Languages : en
Pages : 340
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Book Description
Multicellular organisms require a means of intracellular communication to organize and develop the complex body plan that occurs during embryogenesis and then for cell and organ systems to access and respond to an ever changing environmental milieu. Mediators of this constant exchange of information are growth factors, neurotransmmitters, peptide and protein hormones which bind to cell surface receptors and transduce their signals from the extracellular space to the intracellular compartment. Via multiple signaling pathways, receptors of this general class affect growth, development and differentiation. Smaller hydrophobic signaling molecules, such as steroids and non-steroid hormones, vitamins and metabolic mediators interact with a large family of nuclear receptors. These receptors function as transcription factors affecting gene expression, to regulate the multiple aspects of animal and human physiology, including development, reproduction and homeostasis. The aim of this book is to cover various aspects of intracellular signaling involving hormone receptors.
Author: P. Michael Conn
Publisher: Springer Science & Business Media
ISBN: 159259641X
Category : Medical
Languages : en
Pages : 440
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Book Description
Leading scientists and clinicians create a concise yet comprehensive encyclopedia of the latest scientific and clinical knowledge covering the entire spectrum of endocrinology-from mammalian cells, plants, and insects to animal models and human disease. Their book illuminates the scientific principles underlying all aspects of hormone secretion and hormone action and leads the reader toward a full understanding of the pathogenesis of human endocrine disease. It will be indispensable to physicians and scientists as well as to students who need a high-quality, up-to-date critical survey and reference to endocrinology today.
Author: Antonino Belfiore
Publisher: Springer
ISBN: 9783319446745
Category : Medical
Languages : en
Pages : 0
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Book Description
This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster.
Author: James E. Griffin
Publisher: Oxford University Press, USA
ISBN: 9780195075618
Category : Medical
Languages : en
Pages : 351
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Book Description
Written primarily for medical students, but also of use to graduates and undergraduates, this textbook provides thorough, balanced, and well-illustrated coverage of endocrine physiology. The scope is broad, ranging from molecular mechanisms of hormone action to the clinical assessment of endocrine function. Yet the book maintains a clear focus on basic endocrine functions, using clinical examples to throw light on normal physiology and its regulation. It was developed from a course given at the University of Texas Southwestern Medical School, which has a strong tradition in endocrinology. The second edition has been thoroughly updated, and the discussion of neuroendocrinology has been reworked. There is new material on a diversity of topics, including neuroendocrine and immune system relationships, adrenergic receptors and their interaction with G proteins, signal transduction by the tyrosine kinase family of cell surface receptors, immunometric assays, clinical evaluation of anterior pituitary hormone levels, functions of activin, hypercalcemia of pregnancy, molecular mechanisms of adrenal steroid action, 1-84 PTH, calcitonin, and the regulation of bone remodelling.
Author: K.M.J. Menon, PhD
Publisher: Springer
ISBN: 3319251244
Category : Medical
Languages : en
Pages : 347
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Book Description
This book examines how post-transcriptional mechanisms control endocrine function. This includes newly identified regulatory mechanisms involved in hormone biosynthesis, control of hormone receptors and the outputs of hormone mediated signal transduction. Chapters address endocrine hormones including protein peptide/peptide, steroid, and non-steroidal hormones. The impacts of these mechanisms on disease and health are covered, providing a novel update to the scientific literature. Post-transcriptional regulatory mechanisms play an essential role in controlling dynamic gene expression. The outcome of this regulation includes control of the amount, timing, and location of protein expression. Regulation is mediated by cis-acting RNA sequences and structures and transacting RNA binding proteins and non-coding RNAs, including microRNAs. Recent advances in characterization of these regulatory factors have revealed enormous regulatory potential.
Author: Etienne-Emile Baulieu (ed)
Publisher: Springer Science & Business Media
ISBN: 9780412027918
Category : Medical
Languages : en
Pages : 716
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Book Description
Endocrinology is a field in which enormous advances have been made in the last decade; the rate of discovery of new hormones, hormone-like molecules, receptors, and mechanisms of action is continually advancing. The development of techniques in immunology and molecular biology has led to the possibility of describing in detail the gene structure of many of the compounds involved in hormonal systems. Remarkable homology has been shown between oncogene products and various components of the endocrine network, leading to the asser tion that deregulation of hormonal function is involved in the generation and/or development of cancer. We now know that the central nervous system is both a target and a production site of many hormonal products, and that hormones, neurotransmitters, growth factors and immunopeptides all act through similar mechanisms. The only second messenger known ten years ago was cAMP; today calcium, derivatives of membrane phospholipids, and protein kinases are also known to be mediators of hormone action. The very concept of hormonal systems has been expanded to include not only endocrine secretions but also para- and autohormones and their mechanisms of action; an understanding of their functions will be central to the immediate future of medicine. The discovery of hormonal molecules and endocrine interactions and the subsequent understanding of hormone related pathophysiology has led to the development of new strategies in medical treatment such as fertility control and the management of diabetes.
Author: Antonino Belfiore
Publisher:
ISBN: 9783319273181
Category : Endocrinology
Languages : en
Pages :
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Book Description
"This volume provides comprehensive coverage of the current knowledge of the physiology of the endocrine system and hormone synthesis and release, transport, and action at the molecular and cellular levels. It presents essential as well as in-depth information of value to both medical students and specialists in Endocrinology, Gynecology, Pediatrics, and Internal Medicine. Although it is well established that the endocrine system regulates essential functions involved in growth, reproduction, and homeostasis, it is increasingly being recognized that this complex regulatory system comprises not only hormones secreted by the classic endocrine glands but also hormones and regulatory factors produced by many organs, and involves extensive crosstalk with the neural and immune system. At the same time, our knowledge of the molecular basis of hormone action has greatly improved. Understanding this complexity of endocrine physiology is crucial to prevent endocrine disorders, to improve the sensitivity of our diagnostic tools, and to provide the rationale for pharmacological, immunological, or genetic interventions. It is such understanding that this book is designed to foster."--Publisher's website.
Author: Olga Smirnova
Publisher: Cambridge Scholars Publishing
ISBN: 1527532011
Category : Medical
Languages : en
Pages : 253
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Book Description
Existing textbooks on endocrinology do not link theory to the practical world, and thus lead to students asking themselves “What should I do with all this knowledge?” This volume reduces the gap between theoretical knowledge and its practical applications through clinical references that reflect current trends in the management of endocrine disorders. Clinical problems included at the end of some chapters will help medical students to practice diagnosing and treating common hormonal disorders. Each topic also ends with a list of suggested reading that will allow the reader to gain further insights.
Author: Patricia E. Molina
Publisher: McGraw Hill Professional
ISBN: 9780071402576
Category : Medical
Languages : en
Pages : 320
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Book Description
This concise overview of hormone biological actions introduces basic science principles and their relevance in the clinical expression of disease. Each chapter incorporates a wealth of pedagogical aids including: study questions, learning objectives, and clinical examples.
