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Author: Sheila Weitzman
Publisher: Cambridge University Press
ISBN: 9781139444170
Category : Medical
Languages : en
Pages : 522
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Book Description
As a comprehensive reference on all aspects of the histiocytic disorders, Histiocytic Disorders of Children and Adults stands out a seminal text on the genetics, pathophysiology and clinical management of this wide range of diseases. The chapters, written by acknowledged experts in the field, cover all aspects of hystiocytic disorders, from Langerhans cell histiocytosis and hemophagocytic lymphohistiocytosis, to the uncommon cutaneous and extracutaneous histiocytic disorders. Views on the function of normal histiocytes in the immune system, the pathogenesis, underlying genetic defects, clinical presentation, treatment, controversies in therapy, salvage therapies and the late consequences are discussed in detail. Originally published in 2005, this book will be a valuable resource to clinicians and researchers who wish to learn more about histiocytic disorders.
Author: Sheila Weitzman
Publisher: Cambridge University Press
ISBN: 9781139444170
Category : Medical
Languages : en
Pages : 522
Get Book Here
Book Description
As a comprehensive reference on all aspects of the histiocytic disorders, Histiocytic Disorders of Children and Adults stands out a seminal text on the genetics, pathophysiology and clinical management of this wide range of diseases. The chapters, written by acknowledged experts in the field, cover all aspects of hystiocytic disorders, from Langerhans cell histiocytosis and hemophagocytic lymphohistiocytosis, to the uncommon cutaneous and extracutaneous histiocytic disorders. Views on the function of normal histiocytes in the immune system, the pathogenesis, underlying genetic defects, clinical presentation, treatment, controversies in therapy, salvage therapies and the late consequences are discussed in detail. Originally published in 2005, this book will be a valuable resource to clinicians and researchers who wish to learn more about histiocytic disorders.
Author: Oussama Abla
Publisher: Springer
ISBN: 3319596322
Category : Medical
Languages : en
Pages : 391
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Book Description
This volume provides a comprehensive and world-class review of the field of histiocytic neoplasms and hemophagocytic lymphohistiocytosis (HLH). It reviews all the advances in the field of histiocytoses during the last ten years, particularly with regards to the genomic findings in LCH and other histiocytic neoplasms and the new suggested classification of the histiocytic disorders. Additionally, it features a state-of-the art update on the most recent treatment strategies for LCH, including the results of the last LCH-III international trial, salvage therapies such as reduced-intensity conditioning (RIC) stem cell transplant (SCT), and targeted therapies with BRAF and MEK inhibitors, as well as the challenging cases of CNS-neurodegenerative LCH and its therapeutic perspectives. For primary and secondary HLH the book updates the most recent genetic and pathophysiological findings, including macrophage-activation syndrome (MAS), and includes a special chapter on HLH in adults. Treatment chapters encompass therapy for newly diagnosed HLH and refractory disease as well as stem-cell transplantation and novel therapies. The text also highlights the most recent advances in the treatment of the uncommon histiocytic disorders, such as Erdheim-Chester disease (ECD), Juvenile xanthogranuloma (JXG) and JXG-like conditions, Rosai-Dorfman disease (RDD), and the very rare malignant histiocytoses. Written by international experts in the field, Histiocytic Disorders is a valuable resource for clinicians, researchers, fellows and residents who are interested in or manage histiocytic disorders in children and adults.
Author: Tracy I. George
Publisher: Springer
ISBN: 1493974696
Category : Medical
Languages : en
Pages : 297
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Book Description
This text illustrates bone marrow aspirate, imprint and biopsy specimens showing characteristic features of a wide variety of neoplastic and non-neoplastic conditions. While the focus is on Wright-stained smears and hematoxylin-eosin stained biopsies, other key histochemical and immunohistochemical stains are illustrated that are vital for proper diagnosis. After a brief review of the normal bone marrow, reactive changes in the marrow are illustrated, including the bone marrow response in constitutional disorders and to metabolic changes throughout the body. This is followed by specific infectious disorders in the marrow and other non-neoplastic disorders. The remainder of the Atlas illustrates the various neoplasms that involve the bone marrow, including leukemias, lymphomas and non-hematopoietic neoplasms. The hematologic neoplasms are classified using the 2016 World Health Organization (WHO) classification. This overview of bone marrow disorders illustrates a wide variety of diseases that practicing pathologists and hematologists will encounter in their routine practice.
Author: Nishant Gupta
Publisher: Springer Nature
ISBN: 3030633659
Category : Medical
Languages : en
Pages : 384
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Book Description
This book is a comprehensive reference on diffuse cystic lung diseases (DCLDs). DCLDs are a group of pathophysiologically heterogenous processes that are characterized by the presence of multiple spherical or irregularly shaped, thin-walled, air-filled spaces within the pulmonary parenchyma. In recent years, tremendous advancements have been made in these diseases leading to improved understanding of the underlying pathophysiology, and improved outcomes with targeted therapies. The authors, who are leading experts in the field, delineate DCLDs as a separate category distinct from other interstitial lung diseases, and have created this textbook specifically dedicated to this disease group. This book begins with a chapter introducing the definition and classification of DCLDs. Subsequent chapters address the pathogenic mechanisms underlying pulmonary cyst formation and provide a detailed overview of the radiological and pathological features of DCLDs. The common as well as uncommon causes of DCLDs are comprehensively reviewed in individual chapters, as are the varied clinical presentations and extrapulmonary manifestations, and approaches to management and treatment. The book culminates in a final chapter that presents a practical algorithmic approach to diagnosis that progresses from least invasive to most invasive approaches. This textbook provides a one-stop, comprehensive and integrated, clinical, radiologic, and pathologic overview of DCLDs that will be as useful to the practicing clinician as it is to the clinical investigator.
Author: Xiaoguang Cheng
Publisher: Springer Nature
ISBN: 9813361506
Category : Medical
Languages : en
Pages : 329
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Book Description
This book provides a detailed description of typical imaging features of bone tumors and tumor-like lesions in the shoulder and elbow. Each chapter deals with one major bone tumor or tumor-like lesion, for example, giant cell tumor, bone cyst, osteochondroma, chondrosarcoma, Ewing sarcoma, bone metastases, lymphoma, etc. Typical cases are carefully selected from thousands of clinical cases accompanying with comprehensive imaging information of X-ray, CT and MRI. In-depth analysis and differential diagnostic tips from experienced bone tumor specialist are presented at the end of each case. This book will be useful and worthy to musculoskeletal radiologists, orthopaedic surgeons, general radiologists, and oncologists.
Author: Muin S.A. Tuffaha
Publisher: Springer
ISBN: 3319535773
Category : Medical
Languages : en
Pages : 257
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Book Description
This book offers a comprehensive yet concise overview of immunoprofile of tumors and antibodies used in contemporary surgical pathology, and provides diagnostic algorithms for approaching tumor diagnostics. Immunohistochemistry has become the most important ancillary technique in diagnostic pathology in the last 20 years, and unlike most books on tumor diagnostics, this volume discusses in details immunohistochemical biomarkers, diagnostic approaches and their pitfalls, as well as the immunoprofile of common tumors throughout all systems of human body. With numerous color figures and detailed flowcharts, it appeals to all pathologists be they young residents in training who want a brief introduction to this technique, or specialists in need of a reliable and comprehensive reference resource in tumors diagnostics.
Author: Adekunle M. Adesina
Publisher: Springer
ISBN: 3319334328
Category : Medical
Languages : en
Pages : 327
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Book Description
This text was created to fill a void in the practice of pediatric neuropathology. It is a practical and well-illustrated book representing a collection of interesting, common and unusual tumors for a diagnostic exercise by the reader. The wide reception of the first edition by the pathology community is testament to its relevance and utility in the pathologic diagnosis of pediatric brain tumors. This edition covers topics ranging from neuroimaging, the use of crush and touch preps during intraoperative consultation, classic histological features of pediatric brain tumors, tumor variants, and a miscellaneous group of challenging tumors. Chapters consist of essential diagnostic information and features highlighting recognized variants and their differential diagnoses. A section on molecular pathology and electron microscopy is also included for each tumor category, along with a list of classic reviews and innovative articles on each of the tumor entities as suggested reading at the end of each chapter. Atlas of Pediatric Brain Tumors, Second Edition represents the state of the art in pediatric neuropathology with easy utility beside the microscope.
Author: Michel R. Nasr
Publisher: Springer
ISBN: 3030115151
Category : Medical
Languages : en
Pages : 217
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Book Description
Lymph node pathology is a complex and rapidly evolving field that requires integration of morphologic findings with a number of ancillary studies, as well as clinical information, to diagnose neoplastic and non-neoplastic hematopoietic disorders. Lymphomas are currently classified according to the 2016 Revision of the World Health Organization (WHO) Classification, which emphasizes, and for some diagnoses mandates, the integration of clinical information in diagnostic decision making. Successful collaboration and teamwork between pathology and clinical specialties (especially hematology/oncology) are paramount for excellent patient care. In addition to diagnosis, pathology plays a significant role in lymphoma prognostication and therefore contributes to patient’s management and follow-up. Lymph Node Pathology for Clinicians provides a concise overview of different entities in lymph node pathology with the primary audience being clinicians. Not all entities are covered, but, rather, the most common and/or clinically most relevant ones were included. This text is intended as a quick reference for a clinician to become familiar with pathologic aspects of lymphomas and the thought process of a pathologist. Particular consideration is given to relevant diagnostic and prognostic ancillary studies. Organized with an interdisciplinary approach for effective management of lymph node disorders, this text aims to educate our clinical colleagues on the most important aspects of lymph node pathology.
Author: A. V. Hoffbrand
Publisher:
ISBN: 9780723431152
Category : Medical
Languages : en
Pages : 0
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Book Description
This highly revised and updated atlas is the third edition of an essential reference in the field of hematology. Highly illustrated, this colorful visual diagnostic aid condenses the pathogenesis, clinical, morphological, and investigative aspects of the whole range of blood disorders into one, comprehensive resource. The detailed reproduction of photomicrographs, along with concise, clinically-directed text facilitates the recognition of morphological abnormalities in blood and bone marrow cells. The highly accessible format of this text enables quick and easy reference for anyone using it. Comprehensive coverage the whole range of blood disorders is discussed Highly Illustrated in full colour aids recognition of signs in the cells Concise text with explanatory artworks enables quick and easy reference in the laboratory Explanatory artworks and tables clarifies complex principles, helpful for trainees Brings together pathogenesis, clinical, morphological, investigational and therapeutic aspects Additional coverage of: Newly discovered cytokines (interleukins 9 to 14) Molecular defects in inherited and acquired blood disorders New leukaemia types and thenew classifications of the lymphom
Author: William D. James
Publisher: Elsevier Health Sciences
ISBN: 0323551882
Category : Medical
Languages : en
Pages : 1109
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Book Description
Now in a fully revised thirteenth edition, Andrews' Diseases of the Skin remains your single-volume, must-have resource for core information in dermatology. From residency through clinical practice, this award-winning title ensures that you stay up to date with new tools and strategies for diagnosis and treatment, new entities and newly recognized diseases, and current uses for tried-and-true and newer medications. It's the reference you'll turn to again and again when faced with a clinical conundrum or therapeutically challenging skin disease. - Utilizes a concise, clinically focused, user-friendly format that clearly covers the full range of common and rare skin diseases. - Provides outstanding visual support with 1,340 illustrations – more than 500 new to this edition. - Presents comprehensively updated information throughout, including new and unusual clinical presentations of syphilis, new diagnostic classifications and therapies for vascular anomalies, and an updated pediatric and genodermatosis review. - Covers new and evolving treatments for inflammatory, neoplastic, and blistering skin diseases among others. New biologics and phosphodiesterase inhibitors for psoriasis and atopic dermatitis, JAK inhibitors for alopecia areata and vitiligo, immune checkpoint inhibitors for melanoma and rituximab for pemphigus are all covered. - Features a revised and revamped cutaneous adverse drug reaction section, including novel eruptions from new and emerging chemotherapeutic agents and small molecule/targeted inhibitors. - Discusses new and emerging viruses including Zika and human polyomaviruses.
