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Author: Anil Gupta
Publisher: Springer
ISBN: 9811310351
Category : Medical
Languages : en
Pages : 617
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Book Description
This book combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students. It describes in simple language the intricate pathophysiology of biomolecules in health and in diseases of dental and oral tissues. This book also describes the evolution of biochemistry in a chronological order, provides information about the fundamental chemical structure, classification and biological significance of biomolecules, vitamins and hormones, enriched with flow charts and diagrams for easy understanding and quick reference. It includes chapters on nucleic acids, nutrition and serum enzymes and organ function tests, and offers an innovative approach to familiarize dental students with the biochemical composition of enamel, dentine, cementum and saliva, explaining the biochemical basis of dental caries, periodontal diseases, role of fluorides in caries prophylaxis, fluoride toxicity, and the role of amino acids as anti-hypersensitive agents.
Author: Anil Gupta
Publisher: Springer
ISBN: 9811310351
Category : Medical
Languages : en
Pages : 617
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Book Description
This book combines fundamental concepts of biochemistry and the dental sciences to provide an authentic, coherent and comprehensive text for dental students. It describes in simple language the intricate pathophysiology of biomolecules in health and in diseases of dental and oral tissues. This book also describes the evolution of biochemistry in a chronological order, provides information about the fundamental chemical structure, classification and biological significance of biomolecules, vitamins and hormones, enriched with flow charts and diagrams for easy understanding and quick reference. It includes chapters on nucleic acids, nutrition and serum enzymes and organ function tests, and offers an innovative approach to familiarize dental students with the biochemical composition of enamel, dentine, cementum and saliva, explaining the biochemical basis of dental caries, periodontal diseases, role of fluorides in caries prophylaxis, fluoride toxicity, and the role of amino acids as anti-hypersensitive agents.
Author: G. Csomos
Publisher: Springer Science & Business Media
ISBN: 3642687482
Category : Medical
Languages : en
Pages : 481
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Book Description
Hepatology has come of age in the last decades. Biology of the liver has flour ished long before. As the largest homogeneous organ of the body the liver served as useful model in the development of biochemistry and related discip lines. Only gradually were these biological investigations applied to the clinical study of liver disease. This was particularly stimulated by the recognition that in the greater part of the world, the developing countries and what we now call the Third World, liver disease represents a major threat to overall public health. It leads to morbidity and mortality of persons in their productive years from liver cancer, cirrhosis and parasitic disease, particularly, schistosomiasis. Moreover, the growing emphasis on the social impact of diseases focused on disorders of the liver because malnutrition, poverty, and drug addiction contrib ute greatly to their spread. This is compounded by the increase of alcohol abuse, recently on the rise even in the developing countries. Concern with envi ronmental pollution has also raised the interest in liver diseases, in part because the liver acts as a guardian against polluting chemicals and in part because it is considered, possibly to an exaggerated degree, a vulnerable target of such chemicals.
Author:
Publisher: Elsevier
ISBN: 0080552110
Category : Science
Languages : en
Pages : 630
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Book Description
For over fifty years the Methods in Enzymology series has been the critically acclaimed laboratory standard and one of the most respected publications in the field of biochemistry. The highly relevant material makes it an essential publication for researchers in all fields of life and related sciences. This volume features articles on the topic of osmosensing and osmosignaling written by experts in the field.
Author: P. Fondu
Publisher: Springer Science & Business Media
ISBN: 9780898386400
Category : Medical
Languages : en
Pages : 206
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Book Description
J. DE GROOTE One of the most ominous and troublesome complications of the liver disease is the appearance of hemorrhagic phenomena. Many careful clini cal observations about the relationship of liver function and of bilia ry tree pathology have been published. A vast amount of research work has been devoted to the subject. The severity of the hemorrhagic disor der is usually in relation to the liver disease. In mild chronic hepa titis or short lasting obstruction slight subcutaneous or mucosal blee ding may (lraw the attention of the patient and the doctor, but they are as such far from dangerous. However in acute hepatic insufficiency, in biliary cirrhosis the bleeding tendency is to be considered as a life threatening complication in about half of the cases. Moreover coagulation disturbances aggravate bleeding not only from ruptured oesophageal or gastric varices but also from gastritis or peptic ulcer. 11enometrorrhagia, epistaxis and gingival bleeding may be very trouble some in these conditions. The use of diagnostic procedures sucl. as liver puncture biopsy and peritoneoscopy are often impossible when platelets and prothrombine time are too low. In order to overcome this difficul ty a procedure has been worked out taking a biopsy through a trans jugular catheter placed in the hepatic vein. If a bleeding from the liver occurs it will be in the circulatory system and not cause any trouble.
Author: Pablo Muriel
Publisher: Academic Press
ISBN: 0128043210
Category : Science
Languages : en
Pages : 917
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Book Description
Liver Pathophysiology: Therapies and Antioxidants is a complete volume on morphology, physiology, biochemistry, molecular biology and treatment of liver diseases. It uses an integral approach towards the role of free radicals in the pathogenesis of hepatic injury, and how their deleterious effects may be abrogated by the use of antioxidants. Written by the most prominent authors in the field, this book will be of use to basic and clinical scientists and clinicians working in the biological sciences, especially those dedicated to the study and treatment of liver pathologies. - Presents the most recent advances in hepatology, with a special focus on the role of oxidative stress in liver injury. - Provides in vivo and in vitro models to study human liver pathology. - Explains the beneficial effects of antioxidants on liver diseases. - Contains the most recent and modern treatments of hepatic pathologies, including, but not limited to, stem cells repopulation, gene therapy and liver transplantation.
Author: C. Goresky
Publisher: Springer Science & Business Media
ISBN: 1468426494
Category : Medical
Languages : en
Pages : 414
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Book Description
Jaundice is much more than a clinical sign of liver disease. It is also a pathophysiological disorder. Through studying it we have come to a much better understanding of how the liver functions under normal and abnormal circumstances. In spite of several important advances in this field, it has not recently been the subject of a comprehensive and interdisciplinary review. This Symposium was held in Montreal on May 31 and June 1, 1974, and the experts who participated in it came together for the purpose of reviewing the current status of Jaundice. The Editors sincerely appreciate the outstanding contribution which these experts made to the Second International Symposium of the Canadian Hepatic Foundation. They are also particularly indebted to Valerie M. Price, Executive Director, Canadian Hepatic Foundation, for her invaluable role in the preparation of this publication. Carl A. Goresky Murray M. Fisher v Contents BILIRUBIN CHEMISTRY An Overview of Bilirubin Chemistry 1 A. F. McDonagh The Conjugates of Bilirubin 19 E. R. Gordon Discussion Period. • • 39 R. Schmid, Char:imm BILIRUBIN PRODUCITON 43 Bilirubin Metabolism: An Overview • • • R. Schmid Bilirubin Production fram Non-Erythroid SoUI"Ces • • • • • • • • • • • • • • • • 57 S. H. Robinson Bilirubin Production fram Erythroid Sources 69 U. Muller-Eberhard and E. F. Johnson Induction Mechanisms for Bile Pigment Formation 85 B. A.
Author: Pere Ginès
Publisher: Springer Science & Business Media
ISBN: 1607618664
Category : Medical
Languages : en
Pages : 583
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Book Description
Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.
Author: Barbara H. Bowman
Publisher: Elsevier
ISBN: 1483216500
Category : Science
Languages : en
Pages : 298
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Book Description
Hepatic Plasma Proteins: Mechanisms of Function and Regulation covers the mechanisms of function, inherited variation, and regulation of genes encoding the plasma proteins synthesized in the liver. The book discusses the physiological and clinical implications of human plasma protein abnormalities; the acute-phase reactants; and the variety of human plasma proteinase inhibitors. The text also describes the plasma protein vehicles (transferrin, ceruloplasmin, transthyretin, haptoglobin, hemopexin, and the vitamin D binding protein), as well as cytokines and transcription factors involved in the regulatory process. The protein and gene anatomies are discussed in terms of evolutionary relationships and genetic variations, especially those with mutations causing clinical manifestations. The book also encompasses the mechanisms responsible for tissue specific and developmental expression of plasma protein genes. Geneticists, biochemists, molecular biologists, physicians, and other students of biology will find the book invaluable.
Author: Andrzej Mackiewicz
Publisher: CRC Press
ISBN: 1000141977
Category : Business & Economics
Languages : en
Pages : 706
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Book Description
Acute Phase Proteins covers all major aspects of acute phase proteins (APP) starting with molecular mechanisms regulating their synthesis and ending with their functional significance. The book features 36 chapters addressing such topics as acute phase response and the APP; major APP and their structure and functions; regulation of APP synthesis, the cytokines and hormones implicated in these processes, and molecular mechanisms involved; signal transduction of cytokines in hepatocytes and posttranscriptional processes; and quantitative and qualitative evaluation of APP in clinical practice. The book will be an important reference for immunologists, molecular biologists, cellular biologists, biochemists, and clinical chemists.
Author: K. Jungermann
Publisher: Springer Science & Business Media
ISBN: 1468450417
Category : Medical
Languages : en
Pages : 495
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Book Description
The liver is an exceptionally complex and diverse organ that functions both as an exocrine and an endocrine gland. It secretes bile, which contains many con stituents in addition to bile salts, and it synthesizes and releases many substances in response to the body's demands, including prohormones, albumin, clotting factors, glucose, fatty acids, and various lipoproteins. It has a dual blood supply providing a rich mixture of nutrients and other absorbed substances via the portal vein and oxygen-rich blood via the hepatic artery. This functional heterogeneity is accompanied by cellular heterogeneity. The liver contains many cell types including hepatic parachymal cells, Kiipffer cells, Ito cells, and endothelial cells. The most abundant cell type, the parenchymal cells, are biochemically and structurally heterogeneous. The cells in the oxygen-rich areas of the portal triad appear more dependent on oxidative metabolism, whereas those around the central vein (pericentral, perivenous, or centrolobular areas) are more dependent upon an anaerobic mechanism. Throughout this volume the latter three terms are used synonymously by various authors to indicate the five to eight layers of cells radiating from the central vein. Structural and metabolic heterogeneity of hepatic parenchymal cells has been demonstrated by a variety of approaches, including histochemical, ultra structural, and ultramicrobiochemical studies. This microheterogeneity is linked to the physiological functions of the liver and its response to injurious substances.
