Helicobacter Pylori in the 21st Century

Helicobacter Pylori in the 21st Century PDF Author: Philip Sutton
Publisher: CABI
ISBN: 1845935942
Category : Medical
Languages : en
Pages : 316

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Book Description
This book provides a broad overview of the current understanding of Helicobacter pylori emphasizing its world health impacts. It includes 13 chapters organized into 3 parts: "Pathologies and Treatment", "Host Response" and "Bacterial Defence". Part I (5 chapters) reviews the epidemiology of H. pylori infection, H. pylori infection in Asia, gastric adenocarcinoma, antimicrobial resistance and approaches to treatment, and extragastric manifestations of H. pylori infection. Part II (4 chapters) describes H. pylori-induced acquired immunity and immunoregulation, host genetic factors and susceptibility to H. pylori pathogenesis, innate immune initiators and effectors in H. pylori infection, and H. pylori vaccines. Part III (4 chapters) discusses the importance of H. pylori lipopolysaccharides in gastric adaptation and pathogenesis, H. pylori virulence factors, H. pylori adhesion to the gastric surface, and helicobacteromics. This book is an essential resource for researchers, students and medics in infectious and Helicobacter-associated diseases.

Helicobacter pylori, Gastritis and Peptic Ulcer

Helicobacter pylori, Gastritis and Peptic Ulcer PDF Author: Peter Malfertheiner
Publisher: Springer Science & Business Media
ISBN: 3642753159
Category : Medical
Languages : en
Pages : 479

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Book Description
Helieobaeter pylori has recently been recognized as a new genus according to specific taxonomic criteria; the "popular" name Campylobaeter pylori has been corrected by scientific progress. Following the discovery of the spiral microorgan ism in gastric mucosa by Marshall and Warren in 1982, it took only a few years for H. pylori to become established as a factor in the pathogenesis of gastritis and peptic ulcer disease. Interest in different aspects of H. pylori has grown continuously and has attracted scientists from various medical and biological disciplines such as gastroenterology, microbiology, pathology, immunology, and pharmacology. Indeed H. pylori provides an excellent model for interdisciplinary interaction and cooperation. To promote this concept of interdisciplinary research and exchange of knowledge, a European Campylobacter (Helicobacter) Pylori Study Group was founded in 1987 in Copenhagen. The second meeting of this expanding group was held from October 12-14,1989 in Ulm, FRG. The fact that more than 500 participants attended the conference and that 187 original contributions from all five continents were presented clearly confirmed that H. pylori has "scientifically infected" the whole world. Our understanding of the microbiological and pathogenetic aspects of H. pylori is continuously being challenged as new results follow swifthy from different research areas. This book includes an update and progress report on the various aspects of H. pylori presented and discussed in special workshops held during the meeting in Ulm.

Helicobacter Pylori in the 21st Century

Helicobacter Pylori in the 21st Century PDF Author: Philip Sutton
Publisher: CABI
ISBN: 1845935942
Category : Medical
Languages : en
Pages : 316

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Book Description
This book provides a broad overview of the current understanding of Helicobacter pylori emphasizing its world health impacts. It includes 13 chapters organized into 3 parts: "Pathologies and Treatment", "Host Response" and "Bacterial Defence". Part I (5 chapters) reviews the epidemiology of H. pylori infection, H. pylori infection in Asia, gastric adenocarcinoma, antimicrobial resistance and approaches to treatment, and extragastric manifestations of H. pylori infection. Part II (4 chapters) describes H. pylori-induced acquired immunity and immunoregulation, host genetic factors and susceptibility to H. pylori pathogenesis, innate immune initiators and effectors in H. pylori infection, and H. pylori vaccines. Part III (4 chapters) discusses the importance of H. pylori lipopolysaccharides in gastric adaptation and pathogenesis, H. pylori virulence factors, H. pylori adhesion to the gastric surface, and helicobacteromics. This book is an essential resource for researchers, students and medics in infectious and Helicobacter-associated diseases.

Microbiology of Waterborne Diseases

Microbiology of Waterborne Diseases PDF Author:
Publisher: Academic Press
ISBN: 0124159761
Category : Science
Languages : en
Pages : 719

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Book Description
The second edition of Microbiology of Waterborne Diseases describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. The book is divided into sections covering bacteria, protozoa, and viruses. Other sections detail methods for detecting and identifying waterborne microorganisms, and the ways in which they are removed from water, including chlorine, ozone, and ultraviolet disinfection. The second edition of this handbook has been updated with information on biofilms and antimicrobial resistance. The impact of global warming and climate change phenomena on waterborne illnesses are also discussed. This book serves as an indispensable reference for public health microbiologists, water utility scientists, research water pollution microbiologists environmental health officers, consultants in communicable disease control and microbial water pollution students. Focuses on the microorganisms of most significance to public health, including E. coli, cryptosporidium, and enterovirus Highlights the basic microbiology, clinical features, survival in the environment, and gives a risk assessment for each pathogen Contains new material on antimicrobial resistance and biofilms Covers drinking water and both marine and freshwater recreational bathing waters

Gastritis and Gastric Cancer

Gastritis and Gastric Cancer PDF Author: Paola Tonino
Publisher:
ISBN: 9789535164838
Category :
Languages : en
Pages : 310

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Book Description
This book is a comprehensive overview of invited contributions on Helicobacter pylori infection in gastritis and gastric carcinogenesis. The first part of the book covers topics related to the pathophysiology of gastric mucosal defense system and gastritis including the gastroprotective function of the mucus, the capsaicin-sensitive afferent nerves and the oxidative stress pathway involved in inflammation, apoptosis and autophagy in H. pylori related gastritis. The next chapters deal with molecular pathogenesis and treatment, which consider the role of neuroendocrine cells in gastric disease, DNA methylation in H. pylori infection, the role of antioxidants and phytotherapy in gastric disease. The final part presents the effects of cancer risk factors associated with H. pylori infection. These chapters discuss the serum pepsinogen test, K-ras mutations, cell kinetics, and H. pylori lipopolysaccharide, as well as the roles of several bacterial genes (cagA, cagT, vacA and dupA) as virulence factors in gastric cancer, and the gastrokine-1 protein in cancer progression.

Helicobacter pylori

Helicobacter pylori PDF Author: R.H. Hunt
Publisher: Springer
ISBN: 9789401046206
Category : Medical
Languages : en
Pages : 612

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Book Description
Helicobacter pylori has attracted widening interest from basic scientists and clinical investigators and the information on this organism is increasing exponentially. It is now accepted that H. Pylori is the most important cause of chronic active gastritis. Furthermore, data have confirmed a marked reduction in the relapse rate of both duodenal and gastric ulcer after eradication of the organism. These important clinical observations have served as a strong stimulus to the investigation of the basic mechanisms involved in the pathogenesis of H. pylori-associated inflammation and the subsequent alterations of gastroduodenal function and gastric mucosal architecture. The book contains chapters by a multidisciplinary, international group of basic scientists and clinical investigators who focus on various microbiological aspects of H. pylori, on the role of H. pylori in peptic ulcer and gastric cancer, and the current status of therapy. The book contains the proceedings of the conference on `Helicobacter pylori: Basic Mechanisms to Clinical Cure', held at Amelia Island, Florida, U.S.A., on November 3--6, 1993.

Helicobacter pylori and Gastroduodenal Pathology

Helicobacter pylori and Gastroduodenal Pathology PDF Author: Jose M. Pajares
Publisher: Springer Science & Business Media
ISBN: 3642774865
Category : Medical
Languages : en
Pages : 401

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Book Description
In the rapidly evolving field of Helicobacter infection new data on pathogenetic and pathophysiological mechanism have appeared. New methods which will be more sensitive and specific in the diagnosis of the infection are being developed and in this proceedings the first attempt using PCR technology is published. From the clinical point of view, a challenging aspect that needs clarification, is the observation which suggests an appearance of a correlation between the presence of the bacteria and abdominal pain and other symptoms in children whereas in old age no such correlation is evident. The relationship of H. pylori and gastric cancer is studied with histopathological data and epidemiological approaches. On the treatment side schemes using short courses and new antibiotic combinations are being investigated and preliminary data are reported.

Gastrointestinal Pathology

Gastrointestinal Pathology PDF Author: Gregory Y. Lauwers
Publisher: John Wiley & Sons
ISBN: 1119073030
Category : Medical
Languages : en
Pages : 837

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Book Description
An illustrated guide to best practices when performing and assessing biopsies for GI conditions of all kinds Accurate diagnosis of GI conditions necessarily entails both the careful taking of biopsies and the informed analysis of tissue material. With that being so, gastroenterologists and GI pathologists alike must have a solid understanding of the techniques, handling requirements, and diagnostic characteristics involved if they are to collaborate effectively. Gastrointestinal Pathology has been designed to provide a clinically focussed and richly illustrated guide to real-world scenarios faced by practicing GI specialists, offering step-by-step instruction and professional advice on the correct diagnosis of all major GI conditions. This essential new book includes: Full-color illustrations throughout Complete details of biopsy samples required to diagnose specific conditions Reviews of differential diagnoses Clinical management clues based on pathologic findings Featuring information to improve the practice of all gastroenterologists and GI pathologists, Gastrointestinal Pathology is a practical and every-day resource for the precise diagnosis of a wide range of GI conditions.

Practical Pediatric Gastrointestinal Endoscopy

Practical Pediatric Gastrointestinal Endoscopy PDF Author: George Gershman
Publisher: John Wiley & Sons
ISBN: 1119423414
Category : Medical
Languages : en
Pages : 448

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Book Description
The reference text for all those practicing diagnostic and therapeutic pediatric endoscopy – trainees, trainers, specialist endoscopists, gastroenterologists and hepatologists alike. Practical Pediatric Gastrointestinal Endoscopy, 3rd Edition provides a comprehensive and up-to-date exploration for the performance of endoscopy in infants, children and young adults. Written in the form of a complete "how to" manual and filled with step-by-step instructions, this book seeks to bring newcomers to the field of pediatric gastrointestinal endoscopy quickly up to speed. The book is also highly useful for experienced specialist endoscopists and gastroenterologists to brush up on best practice in standard techniques and explore advanced topics in the field. Practical Pediatric Gastrointestinal Endoscopy highlights the substantial and important differences between performing an endoscopy on a mature adult and performing one in a pediatric patient. The differences discussed include: GI pathology Subtleties of diagnostic technique specific to children Application of therapeutic endoscopy to specifically pediatric scenarios Anesthesia and sedation Training and skill maintenance Sophisticated endoscopic techniques adapted from adult endoscopy to children and those techniques specifically orientated to problems and diseases mainly encountered in childhood. This guide is becoming an essential companion for those of us providing diagnostic and therapeutic endoscopy for children in the world today and opens the door to future possibilities in this ever-evolving field.

Experimental and Quasi-experimental Designs for Generalized Causal Inference

Experimental and Quasi-experimental Designs for Generalized Causal Inference PDF Author: William R. Shadish
Publisher: Cengage Learning
ISBN:
Category : Education
Languages : en
Pages : 664

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Book Description
Sections include: experiments and generalised causal inference; statistical conclusion validity and internal validity; construct validity and external validity; quasi-experimental designs that either lack a control group or lack pretest observations on the outcome; quasi-experimental designs that use both control groups and pretests; quasi-experiments: interrupted time-series designs; regresssion discontinuity designs; randomised experiments: rationale, designs, and conditions conducive to doing them; practical problems 1: ethics, participation recruitment and random assignment; practical problems 2: treatment implementation and attrition; generalised causal inference: a grounded theory; generalised causal inference: methods for single studies; generalised causal inference: methods for multiple studies; a critical assessment of our assumptions.

Social Inequalities and Cancer

Social Inequalities and Cancer PDF Author: Manolis Kogevinas
Publisher: Iarc
ISBN:
Category : Health & Fitness
Languages : en
Pages : 420

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Book Description
In both industrialized and lessdeveloped societies, cancer incidence and survival are related to socioeconomic factors. This fascinating volume, the first to examine the magnitude of these socioeconomic differences in relation to cancer, provides vital information for all those interested in public health. Cancer incidence and survival are related to socioeconomic status in both industrialized and less developed countries. These differences can be explained, in part, by known risk factors, particularly tobacco smoke, occupational exposures, reproductive behaviour, diet and biological agents. T.