Hayes' Principles and Methods of Toxicology, Sixth Edition

Hayes' Principles and Methods of Toxicology, Sixth Edition PDF Author: A. Wallace Hayes
Publisher: CRC Press
ISBN: 1842145363
Category : Medical
Languages : en
Pages : 2186

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Book Description
Hayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.

Hayes' Principles and Methods of Toxicology, Sixth Edition

Hayes' Principles and Methods of Toxicology, Sixth Edition PDF Author: A. Wallace Hayes
Publisher: CRC Press
ISBN: 1842145363
Category : Medical
Languages : en
Pages : 2186

Get Book Here

Book Description
Hayes’ Principles and Methods of Toxicology has long been established as a reliable reference to the concepts, methodologies, and assessments integral to toxicology. The new sixth edition has been revised and updated while maintaining the same high standards that have made this volume a benchmark resource in the field. With new authors and new chapters that address the advances and developments since the fifth edition, the book presents everything toxicologists and students need to know to understand hazards and mechanisms of toxicity, enabling them to better assess risk. The book begins with the four basic principles of toxicology—dose matters, people differ, everything transforms, and timing is crucial. The contributors discuss various agents of toxicity, including foodborne, solvents, crop protection chemicals, radiation, and plant and animal toxins. They examine various methods for defining and measuring toxicity in a host of areas, including genetics, carcinogenicity, toxicity in major body systems, and the environment. This new edition contains an expanded glossary reflecting significant changes in the field. New topics in this edition include: The importance of dose–response Systems toxicology Food safety The humane use and care of animals Neurotoxicology The comprehensive coverage and clear writing style make this volume an invaluable text for students and a one-stop reference for professionals.

Information Resources in Toxicology, Volume 1: Background, Resources, and Tools

Information Resources in Toxicology, Volume 1: Background, Resources, and Tools PDF Author:
Publisher: Academic Press
ISBN: 0128137258
Category : Technology & Engineering
Languages : en
Pages : 1055

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Book Description
This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology's subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools.Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology's presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field.The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving increased emphasis are disaster preparedness, nanotechnology, -omics, risk assessment, societal implications such as ethics and the precautionary principle, climate change, and children's environmental health. - Introductory chapters provide a backdrop to the science of toxicology, its history, the origin and status of toxicoinformatics, and starting points for identifying resources - Offers an extensive array of chapters organized by subject, each highlighting resources such as journals, databases,organizations, and review articles - Includes chapters with an emphasis on format such as government reports, general interest publications, blogs, and audiovisuals - Explores recent internet trends, web-based databases, and software tools in a section on the online environment - Concludes with a miscellany of special topics such as laws and regulations, chemical hazard communication resources, careers and professional education, K-12 resources, funding, poison control centers, and patents - Paired with Volume Two, which focuses on global resources, this set offers the most comprehensive compendium of print, digital, and organizational resources in the toxicological sciences with over 120 chapters contributions by experts and leaders in the field

Hayes' Principles and Methods of Toxicology

Hayes' Principles and Methods of Toxicology PDF Author: A. Wallace Hayes
Publisher: CRC Press
ISBN: 1000875776
Category : Medical
Languages : en
Pages : 2143

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Book Description
Hayes’ Principles and Methods of Toxicology has long been established as a reliable and informative reference for the concepts, methodologies, and assessments integral to toxicology. The new edition contains updated and new chapters with the addition of new authors while maintaining the same high standards that have made this book a benchmark resource in the field. Key Features: The comprehensive yet concise coverage of various aspects of fundamental and applied toxicology makes this book a valuable resource for educators, students, and professionals. Questions provided at the end of each chapter allow readers to test their knowledge and understanding of the material covered. All chapters have been updated and over 60 new authors have been added to reflect the dynamic nature of toxicological sciences New topics in this edition include Safety Assessment of Cosmetics and Personal Care Products, The Importance of the Dose/Rate Response, Novel Approaches and Alternative Models, Epigenetic Toxicology, and an Expanded Glossary. The volume is divided into 4 major sections, addressing fundamental principles of toxicology (Section I. "Principles of Toxicology"), major classes of established chemical hazards (Section II. "Agents"), current methods used for the assessment of various endpoints indicative of chemical toxicity (Section III. "Methods"), as well as toxicology of specific target systems and organs (Section IV. "Organ- and System-Specific Toxicology"). This volume will be a valuable tool for the audience that wishes to broaden their understanding of hazards and mechanisms of toxicity and to stay on top of the emerging methods and concepts of the rapidly advancing field of toxicology and risk assessment.

Chemical Warfare Agents

Chemical Warfare Agents PDF Author: Brian J. Lukey
Publisher: CRC Press
ISBN: 0429632967
Category : Medical
Languages : en
Pages : 849

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Book Description
The first edition of this book, Chemical Warfare Agents: Toxicity at Low Levels, was published just prior to the terrorist attacks of September 11, 2001. The second edition titled, Chemical Warfare Agents: Pharmacology, Toxicology, and Therapeutics, included new epidemiological and clinical studies of exposed or potentially exposed populations; new treatment concepts and products; improved organization of the national response apparatus addressing the potential for CWA terrorism; and improved diagnostic tests that enable rapid diagnosis and treatment. Since the second edition, the chemical warfare agent community has worked hard to advance research for protection and treatment and develop/improve response approaches for individuals and definitive care. Consequently, in addition to updating previous chapters, Chemical Warfare Agents: Biomedical and Psychological Effects, Medical Countermeasures, and Emergency Response, Third Edition features several new chapters that address the Syrian War, chemical destruction, the Organisation for the Prohibition of Chemical Weapons, biomarkers for chemical warfare agent exposure, field sensors, aircraft decontamination, lung/human on a chip, chemical warfare response decision making, and other research advancements. Features: Describes the newest medical interventions, and the latest technologies deployed in the field, as well as developments in the international response to CW usage highlighting recent events in the Middle East Discusses the latest in organizational/interagency partitioning in terms of responsibilities for emergency response, not just in the United States but at the international level—whether prevention, mitigation, medical care, reclamation, or medico-legal aspects of such response Contains the most current research from bench-level experts The third edition contains the most up-to-date and comprehensive coverage of the question of chemical warfare agent employment on the battlefield or in terrorism. Edited by workers that have been in the field for 35+ years, it remains faithful to the scientific "constants," while evaluating and crediting the advances by the industry that have made us safer.

Hazardous Wastes

Hazardous Wastes PDF Author: Richard J. Watts
Publisher: John Wiley & Sons
ISBN: 1119634059
Category : Science
Languages : en
Pages : 724

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Book Description
Hazardous Wastes An illuminating, problem-solving approach to source area analysis, environmental chemodynamics, risk assessment, and remediation In the newly revised second edition of Hazardous Wastes: Assessment and Remediation, a team of distinguished researchers delivers a foundational and comprehensive treatment of all aspects of hazardous waste problems. The book offers two sections—one on assessment and the following on remediation—while exploring topics crucial to the study of environmental science and engineering at the senior or master’s level. This latest edition includes a new emphasis on the chemistry of emerging contaminants, including perfluorinated compounds, 1,4-dioxane, methyl tert-butyl ether, and personal care products. It also offers updated data on contaminant Threshold Limit Value, Reference Dose, Slope Factor, Reference Concentration, and Inhalation Unit Risk. New remediation chapters also provide many design problems, incorporating economic analyses and the selection of various design alternatives. Approximately 200 new end-of-chapter problems—with solutions—have been added as well. Readers will also find: A thorough introduction to hazardous wastes, including discussion of pre-regulatory disposal and hazardous waste legislation Comprehensive discussions of common hazardous wastes, including their nomenclature, industrial uses, and disposal histories In-depth explorations of partitioning, sorption, and exchange at surfaces, as well as volatilization Extensive descriptions of the concepts of hazardous waste toxicology and quantitative toxicology Perfect for senior- and masters-level college courses in hazardous wastes in Environmental Science, Environmental Engineering, Civil Engineering, or Chemical Engineering programs, Hazardous Wastes: Assessment and Remediation will also earn a place in the libraries of professional environmental scientists and engineers.

Regulatory Toxicology, Third Edition

Regulatory Toxicology, Third Edition PDF Author: Shayne C. Gad
Publisher: CRC Press
ISBN: 0429876513
Category : Medical
Languages : en
Pages : 311

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Book Description
This practical book provides toxicologists with essential information on the regulations that govern their jobs and products. Regulatory Toxicology, Third Edition is an up-to-date guide to required safety assessment for the entire range of man-made marketed products. Individual chapters written by experts with extensive experience in the field address requirements not only for human pharmaceuticals and medical devices (for which there are available guidances), but for the full range of man-made products. New in this edition are three chapters addressing Safety Data Sheet Preparation, Regulatory Requirements for GMOs, and Regulatory Requirements for Tobacco and Marijuana. The major administrative divisions for regulatory agencies and their main responsibilities are also detailed, as are the basic filing documents the agencies require. Coverage includes food additives, dietary supplements, cosmetics, over-the-counter drugs, personal care and consumer products, agriculture and GMO products, industrial chemicals, air and drinking water regulations and the special cases of California’s Proposition 65, requirements for safety data sheets, and oversight regulations. Both US and international requirements are clearly presented and referenced. In one volume, those who have regulatory responsibility in companies, lawyers, educators, and those selling these materials in the marketplace can learn about regulatory requirements and how to meet them.

Veterinary Toxicology

Veterinary Toxicology PDF Author: Ramesh C Gupta
Publisher: Academic Press
ISBN: 0128114118
Category : Medical
Languages : en
Pages : 1239

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Book Description
Veterinary Toxicology, Basic and Clinical Principles, Third Edition, is a unique, single reference that teaches the basic principles of veterinary toxicology to any student at the DVM, MS or PhD level. While comparable texts are primarily directed on the field of human toxicology, this text thoroughly prepares toxicologists and students on the newest approaches for diagnosing chemical and plant poisoning cases in animals. Many chapters on topics not covered in any previous books are provided, such as target organ toxicity, radiation and radioactive materials, FDA regulatory issues, and ethics in veterinary toxicology. Completely revised and updated to include the most recent developments in the field, including new toxins, methods and regions, this book is an essential resource for advanced students and researchers in toxicology, practicing veterinary toxicologists, poison control centers, marine biologists, environmentalists and animal scientists. - Provides a complete, up-to-date, integrated source of information on toxins and poisons relating to animals - Covers all important aspects of veterinary toxicology with completely updated and revised chapters - Includes basic principles of a key toxicology concept, along with clinical applications and a list of major references for further reading

Explaining Risk Analysis

Explaining Risk Analysis PDF Author: Michael R Greenberg
Publisher: Taylor & Francis
ISBN: 131729842X
Category : Business & Economics
Languages : en
Pages : 339

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Book Description
Risk analysis is not a narrowly defined set of applications. Rather, it is widely used to assess and manage a plethora of hazards that threaten dire implications. However, too few people actually understand what risk analysis can help us accomplish and, even among experts, knowledge is often limited to one or two applications. Explaining Risk Analysis frames risk analysis as a holistic planning process aimed at making better risk-informed decisions and emphasizing the connections between the parts. This framework requires an understanding of basic terms, including explanations of why there is no universal agreement about what risk means, much less risk assessment, risk management and risk analysis. Drawing on a wide range of case studies, the book illustrates the ways in which risk analysis can help lead to better decisions in a variety of scenarios, including the destruction of chemical weapons, management of nuclear waste and the response to passenger rail threats. The book demonstrates how the risk analysis process and the data, models and processes used in risk analysis will clarify, rather than obfuscate, decision-makers’ options. This book will be of great interest to students and scholars of risk assessment, risk management, public health, environmental science, environmental economics and environmental psychology.

Pyrolysis of Organic Molecules

Pyrolysis of Organic Molecules PDF Author: Serban C. Moldoveanu
Publisher: Elsevier
ISBN: 0080932150
Category : Science
Languages : en
Pages : 737

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Book Description
Pyrolysis of Organic Molecules with Applications to Health and Environmental Issues, the 28th volume in the Techniques and Instrumentation in Analytical Chemistry series, gives a systematic and comprehensive description of pyrolysis of non-polymeric organic molecules. Pyrolysis is involved in many practical applications as well as in many common human activities, but harmful compounds can be generated in the process. The study of pyrolysis and of the formation of undesirable compounds as a result of pyrolytic processes is of considerable interest to chemists, chemical engineers, and toxicologists. - Pyrolysis results for compounds not previously studied or reported - Updated information from a large body of results published on pyrolysis of individual compounds or classes of compounds - Information on mechanisms and kinetics of numerous pyrolytic processes

Toxicology of the Gastrointestinal Tract, Second Edition

Toxicology of the Gastrointestinal Tract, Second Edition PDF Author: Shayne Cox Gad
Publisher: CRC Press
ISBN: 042978144X
Category : Medical
Languages : en
Pages : 477

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Book Description
Nanoparticles as both potential unique risks and as a valuable approach to increased and higher specificity in delivery of therapeutics A primer on the largest, most diverse, and important microbiome in any mammal "Tricks of the trade" on modifying the oral administration of drugs