Handbook of the Extracellular Matrix PDF Download
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Author: F. Raquel Maia
Publisher: Springer Nature
ISBN: 3031563638
Category :
Languages : en
Pages : 1322
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Book Description
Author: F. Raquel Maia
Publisher: Springer Nature
ISBN: 3031563638
Category :
Languages : en
Pages : 1322
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Book Description
Author: Anthony Atala
Publisher: Academic Press
ISBN: 0123814235
Category : Science
Languages : en
Pages : 1203
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Book Description
Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. - Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology - The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine - New discoveries from leading researchers on restoration of diseased tissues and organs
Author: Steven M. Kurtz
Publisher: Academic Press
ISBN: 008088444X
Category : Technology & Engineering
Languages : en
Pages : 564
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Book Description
UHMWPE Biomaterials Handbook describes the science, development, properties and application of of ultra-high molecular weight polyethylene (UHMWPE) used in artificial joints. This material is currently used in 1.4 million patients around the world every year for use in the hip, knee, upper extremities, and spine. Since the publication of the 1st edition there have been major advances in the development and clinical adoption of highly crosslinked UHMWPE for hip and knee replacement. There has also been a major international effort to introduce Vitamin E stabilized UHMWPE for patients. The accumulated knowledge on these two classes of materials are a key feature of the 2nd edition, along with an additional 19 additional chapters providing coverage of the key engineering aspects (biomechanical and materials science) and clinical/biological performance of UHMWPE, providing a more complete reference for industrial and academic materials specialists, and for surgeons and clinicians who require an understanding of the biomaterials properties of UHMWPE to work successfully on patient applications. - The UHMWPE Handbook is the comprehensive reference for professionals, researchers, and clinicians working with biomaterials technologies for joint replacement - New to this edition: 19 new chapters keep readers up to date with this fast moving topic, including a new section on UHMWPE biomaterials; highly crosslinked UHMWPE for hip and knee replacement; Vitamin E stabilized UHMWPE for patients; clinical performance, tribology an biologic interaction of UHMWPE - State-of-the-art coverage of UHMWPE technology, orthopedic applications, biomaterial characterisation and engineering aspects from recognised leaders in the field
Author: Steven M. Kurtz
Publisher: William Andrew
ISBN: 143774463X
Category : Medical
Languages : en
Pages : 309
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Book Description
PEEK biomaterials are currently used in thousands of spinal fusion patients around the world every year. Durability, biocompatibility and excellent resistance to aggressive sterilization procedures make PEEK a polymer of choice, replacing metal in orthopedic implants, from spinal implants and hip replacements to finger joints and dental implants. This Handbook brings together experts in many different facets related to PEEK clinical performance as well as in the areas of materials science, tribology, and biology to provide a complete reference for specialists in the field of plastics, biomaterials, medical device design and surgical applications. Steven Kurtz, author of the well respected UHMWPE Biomaterials Handbook and Director of the Implant Research Center at Drexel University, has developed a one-stop reference covering the processing and blending of PEEK, its properties and biotribology, and the expanding range of medical implants using PEEK: spinal implants, hip and knee replacement, etc. Covering materials science, tribology and applications Provides a complete reference for specialists in the field of plastics, biomaterials, biomedical engineering and medical device design and surgical applications
Author: Gilson Khang
Publisher: CRC Press
ISBN: 9814745138
Category : Medical
Languages : en
Pages : 1480
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Book Description
Millions of patients suffer from end-stage organ failure or tissue loss annually, and the only solution might be organ and/or tissue transplantation. To avoid poor biocompatibility–related problems and donor organ shortage, however, around 20 years ago a new, hybridized method combining cells and biomaterials was introduced as an alternative to whole-organ and tissue transplantation for diseased, failing, or malfunctioning organs—regenerative medicine and tissue engineering. This handbook focuses on all aspects of intelligent scaffolds, from basic science to industry to clinical applications. Its 10 parts, illustrated throughout with excellent figures, cover stem cell engineering research, drug delivery systems, nanomaterials and nanodevices, and novel and natural biomaterials. The book can be used by advanced undergraduate- and graduate-level students of stem cell and tissue engineering and researchers in macromolecular science, ceramics, metals for biomaterials, nanotechnology, chemistry, biology, and medicine, especially those interested in tissue engineering, stem cell engineering, and regenerative medicine.
Author: Rui L. Reis
Publisher: Elsevier
ISBN: 1845694813
Category : Science
Languages : en
Pages : 829
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Book Description
Polymers from natural sources are particularly useful as biomaterials and in regenerative medicine, given their similarity to the extracellular matrix and other polymers in the human body. This important book reviews the wealth of research on both tried and promising new natural-based biomedical polymers, together with their applications as implantable biomaterials, controlled-release carriers or scaffolds for tissue engineering.The first part of the book reviews the sources, processing and properties of natural-based polymers for biomedical applications. Part two describes how the surfaces of polymer-based biomaterials can be modified to improve their functionality. The third part of the book discusses the use of natural-based polymers for biodegradable scaffolds and hydrogels in tissue engineering. Building on this foundation, Part four looks at the particular use of natural-gelling polymers for encapsulation, tissue engineering and regenerative medicine. The penultimate group of chapters reviews the use of natural-based polymers as delivery systems for drugs, hormones, enzymes and growth factors. The final part of the book summarises research on the key issue of biocompatibility.Natural-based polymers for biomedical applications is a standard reference for biomedical engineers, those studying and researching in this important area, and the medical community. - Examines the sources, processing and properties of natural based polymers for biomedical applications - Explains how the surfaces of polymer based biomaterials can be modified to improve their functionality - Discusses the use of natural based polymers for hydrogels in tissue engineering, and in particular natural gelling polymers for encapsulation and regenerative medicine
Author: James S. Lowe
Publisher: Elsevier Health Sciences
ISBN: 0323612806
Category : Medical
Languages : en
Pages : 439
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Book Description
Easy to read, well organized, and focused on high-yield content, Human Histology, 5th Edition, features concise, up-to-date coverage of the core knowledge in this complex field. Ideal for students in all areas of health care, this revised edition is aligned with recent developments in integrated and problem-based learning, providing rapid access to relevant, practical knowledge in histology. It provides students with opportunities to make important connections between histological knowledge, cell biology, anatomy, clinical understanding, and assessment. - Features an easy-to-navigate, full-colour layout that includes summary headings, readable text, quick-reference tables, and key facts – all highlighted by nearly 900 clear illustrations, photos, and graphics throughout. - Covers the latest concepts and advances in histology including developments in the primary cilium, the nuclear pore, extracellular matrix components, dendritic spines, subsets of astrocytes, haematopoiesis, classification of cells in the immune system, macrophage subsets, and much more. - Includes NEW self-assessment questions. - Provides just the right amount of detail for maximum readability and retention. - Highlights key laboratory, clinical, and high-level scientific material in boxes. - Presents advanced concepts such as the molecular and functional relevance of histological features. - Provides review material in the book and online, self-assessment questions plus 180 additional review questions online. - Evolve Instructor Resources, including a downloadable image and test bank, are available to instructors through their Elsevier sales rep or via request at: https://evolve.elsevier.com
Author: Robert Mecham
Publisher: Springer Science & Business Media
ISBN: 3642165559
Category : Science
Languages : en
Pages : 429
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Book Description
Knowledge of the extracellular matrix (ECM) is essential to understand cellular differentiation, tissue development, and tissue remodeling. This volume of the series “Biology of Extracellular Matrix” provides a timely overview of the structure, regulation, and function of the major macromolecules that make up the extracellular matrix. It covers topics such as collagen types and assembly of collagen-containing suprastructures, basement membrane, fibronectin and other cell-adhesive glycoproteins, proteoglycans, microfibrils, elastin, fibulins and matricellular proteins, such as thrombospondin. It also explores the concept that ECM components together with their cell surface receptors can be viewed as intricate nano-devices that allow cells to physically organize their 3-D-environment. Further, the role of the ECM in human disease and pathogenesis is discussed as well as the use of model organisms in elucidating ECM function.
Author: Thomas D. Pollard
Publisher: Elsevier Health Sciences
ISBN: 0323400027
Category : Science
Languages : en
Pages : 900
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Book Description
The much-anticipated 3rd edition of Cell Biology delivers comprehensive, clearly written, and richly illustrated content to today's students, all in a user-friendly format. Relevant to both research and clinical practice, this rich resource covers key principles of cellular function and uses them to explain how molecular defects lead to cellular dysfunction and cause human disease. Concise text and visually amazing graphics simplify complex information and help readers make the most of their study time. - Clearly written format incorporates rich illustrations, diagrams, and charts. - Uses real examples to illustrate key cell biology concepts. - Includes beneficial cell physiology coverage. - Clinically oriented text relates cell biology to pathophysiology and medicine. - Takes a mechanistic approach to molecular processes. - Major new didactic chapter flow leads with the latest on genome organization, gene expression and RNA processing. - Boasts exciting new content including the evolutionary origin of eukaryotes, super resolution fluorescence microscopy, cryo-electron microscopy, gene editing by CRISPR/Cas9, contributions of high throughput DNA sequencing to understand genome organization and gene expression, microRNAs, IncRNAs, membrane-shaping proteins, organelle-organelle contact sites, microbiota, autophagy, ERAD, motor protein mechanisms, stem cells, and cell cycle regulation. - Features specially expanded coverage of genome sequencing and regulation, endocytosis, cancer genomics, the cytoskeleton, DNA damage response, necroptosis, and RNA processing. - Includes hundreds of new and updated diagrams and micrographs,plus fifty new protein and RNA structures to explain molecular mechanisms in unprecedented detail. - Student Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, images, and over a dozen animations from the book on a variety of devices.
Author: Suguru Nakamura
Publisher: CRC Press
ISBN: 9814411922
Category : Medical
Languages : en
Pages : 484
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Book Description
This handbook on vacuolar and plasma membrane H+-ATPases is the first to focus on an essential link between vacuolar H+-ATPase and the glycolysis metabolic pathway to understand the mechanism of diabetes and the metabolism of cancer cells. It presents recent findings on the structure and function of vacuolar H+-ATPase in glucose promoting assembly
