Handbook of Mitochondrial Dysfunction

Handbook of Mitochondrial Dysfunction PDF Author: Shamim I. Ahmad
Publisher: CRC Press
ISBN: 0429811772
Category : Medical
Languages : en
Pages : 503

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Book Description
Mitochondria produce the chemical energy necessary for eukaryotic cell functions; hence mitochondria are an essential component of health, playing roles in both disease and aging. More than 80 human diseases and syndromes are associated with mitochondrial dysfunction; this book focuses upon diseases linked to these ubiquitous organelles. Accumulation of mitochondrial DNA damage results in mitochondrial dysfunction through two main pathways. Mutation in mitochondrial DNA causes diseases such as Kearns-Sayre syndrome and Pearson syndrome. Mutation in chromosomal DNA causes diseases such as Parkinson's disease and schizophrenia. These and many other diseases are reviewed in this book. Key Features Presents the detailed structure of mitochondria, mitochondrial function, roles of oxidants and antioxidants in mitochondrial dysfunction. Includes summary of both causes and effects of these diseases. Discusses current and potential future therapies for mitochondrial dysfunction diseases Explores a wide variety of diseases caused by dysfunctional mitochondria.

Living Well with Mitochondrial Disease

Living Well with Mitochondrial Disease PDF Author: Cristy Balcells
Publisher:
ISBN: 9781606130148
Category : Mitochondrial pathology
Languages : en
Pages : 0

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Book Description
Living Well with Mitochondrial Disease helps make sense of mitochondrial disease (Mito), an overwhelming and complex group of diagnoses that has grown exponentially in recent years. The most common metabolic disorder, thought to be more common than cystic fibrosis and broader-reaching than most genetic diseases, Mito can affect babies, children, and teens from birth or at any point during their development. Previously healthy adults, as well as adults with a history of unexplained fatigue, are increasingly receiving a Mito diagnosis. Some children with autism spectrum disorders who have medical issues such as digestive difficulties and fatigue are also being identified as having a mitochondrial disorder. This guide is the first book about Mito written for patients and thier families. It takes readers from understanding how the mitochondria work (they are the powerhouse of the cell, providing energy for the entire body), how people with mitochondrial defects are diagnosed and treated, to how to live well when you, your child, or someone you love is struggling with disabling symptoms. Topics include: the journey to diagnosis; the biochemistry of Mito; practical advice for the specific needs of children and adults; understanding and managing symptoms; where to find specialists and support; treatment approaches; and autism and Mito. Writing from the perspective of both a parent and nurse, the author shows adult patients, parents, family members, and caregivers how to achieve the best quality of life possible. Readers will feel empowered as they come to understand the causes of Mito, learn to manage the symptoms, avoid emergencies and make appropriate lifestyle choices.

The Routledge Handbook on Biochemistry of Exercise

The Routledge Handbook on Biochemistry of Exercise PDF Author: Peter M. Tiidus
Publisher: Routledge
ISBN: 100028445X
Category : Medical
Languages : en
Pages : 585

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Book Description
Very comprehensive and well-organized Handbook covering fundamental acute and chronic aspects of exercise and training, plus nutrition and ergogenic aids, and application to disease. Incorporates much of the new research that has been generated over the past decade, which has yet to be presented in a text book. The presented chapters comprehensively cover all aspects of exercise biochemistry Brings together an international and exceptional editorial team and contributing authors

Pharmacology of Mitochondria

Pharmacology of Mitochondria PDF Author: Harpreet Singh
Publisher: Springer
ISBN: 3319573136
Category : Medical
Languages : en
Pages : 491

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Book Description
This special book is conceived to highlight mitochondrial structural and functional integrity and how they are associated with several human diseases such as cardiovascular, cancer, renal, neurological disorder, and genetic disorders. The chapters contributed by leading mitochondrial researchers in the handbook will take us through the novel pharmacological strategies via mitochondria to understand their physiological and pathological role as well as present them as therapeutic targets.

Handbook of Pediatric Anesthesia

Handbook of Pediatric Anesthesia PDF Author: Manon Hache
Publisher: McGraw-Hill Education / Medical
ISBN: 9780071769358
Category : Medical
Languages : en
Pages : 400

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Book Description
Sharpen your clinical decision-making skills with this concise handbook of anesthesia care for children Written by the pediatric anesthesia faculty at Columbia University Medical Center, Handbook of Pediatric Anesthesia is a succinct guide to the practice of clinical anesthesia in neonates, infants, children, and adolescents. Each of the 89 chapters is devoted to a specific illness or disorder and is presented in a consistent, easy-access design. Every chapter includes a case description, perioperative considerations, anesthetic management, postoperative considerations, controversies, and surgical concerns for the illness discussed. Covering the entire breadth of the specialty, Handbook of Pediatric Anesthesia is an outstanding introductory text and an essential review for pediatric anesthesia board certification and recertification. It is especially valuable to residents and trainees as well as practicing anesthesiologists who do not manage pediatric cases on a regular basis. The book concludes with detailed appendices, including a Pediatric Critical Event Checklist and a Pediatric Drug Guide.

Handbook of Photomedicine

Handbook of Photomedicine PDF Author: Michael R. Hamblin
Publisher: Taylor & Francis
ISBN: 1439884706
Category : Medical
Languages : en
Pages : 854

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Book Description
Providing the most comprehensive, up-to-date coverage of this exciting biomedical field, Handbook of Photomedicine gathers together a large team of international experts to give you a complete account of the application of light in healthcare and medical science. The book progresses logically from the history and fundamentals of photomedicine to di

Mitochondria in Health and Disease

Mitochondria in Health and Disease PDF Author: Ray Griffiths
Publisher: Singing Dragon
ISBN: 0857012886
Category : Health & Fitness
Languages : en
Pages : 338

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Book Description
What are the functions of mitochondria in the human body? Why might they stop working properly and what can happen as a result? How can personalized nutrition help to optimize mitochondrial function and prevent or address chronic conditions? This innovative book explores the incredibly complex biochemical roles of mitochondria in health and disease. When healthy, mitochondria provide us with ninety percent of our body's energy. When unhealthy, this can lead to many chronic and degenerative conditions including cancer and Alzheimer's disease. This guide helps practitioners to identify the mitochondrial dysfunction underlying a wide range of health complaints, and provides inspiration about relevant and emerging mitochondria-supportive dietary regimes and nutrients to explore within the model of personalized nutrition.

Diabetes and the Nervous System

Diabetes and the Nervous System PDF Author: Douglas W. Zochodne
Publisher: Elsevier
ISBN: 9780444534804
Category : Medical
Languages : en
Pages : 0

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Book Description
This is a unique compilation, by experts worldwide, addressing how diabetes impacts the nervous system. For example, diabetic polyneuropathy, a disorder more common than MS, Parkinson's disease, and ALS combined, is a major source of disability to diabetic persons worldwide. This book addresses diabetic polyneuropathy and how diabetes alters other parts of the nervous system.

Neurogenetics, Part I

Neurogenetics, Part I PDF Author:
Publisher: Elsevier
ISBN: 0444632352
Category : Medical
Languages : en
Pages : 438

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Book Description
Genetic methodologies are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is evolving rapidly and expected to grow in scope as more disorders are linked to specific genetic markers. Part I covers basic genetic concepts and recurring biological themes, and begins the discussion of movement disorders and neurodevelopmental disorders, leading the way for Part II to cover a combination of neurological, neuromuscular, cerebrovascular, and psychiatric disorders. This volume in the Handbook of Clinical Neurology will provide a comprehensive introduction and reference on neurogenetics for the clinical practitioner and the research neurologist. - Presents a comprehensive coverage of neurogenetics - Details the latest science and impact on our understanding of neurological psychiatric disorders - Provides a focused reference for clinical practitioners and the neuroscience/neurogenetics research community

Handbook of Lipids in Human Function

Handbook of Lipids in Human Function PDF Author: Ronald Ross Watson
Publisher: Academic Press and AOCS Press
ISBN: 9781630670368
Category : Technology & Engineering
Languages : en
Pages : 0

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Book Description
Handbook of Lipids in Human Function: Fatty Acids presents current research relating to health issues whose impact may be modified by adopting personalized diets and lifestyle interventions of the consumption of fatty acids. Addressing cardiovascular and neurological diseases as well as cancer, obesity, inflammatory conditions, and lung disease, the authors correlate lipid sources with specific conditions, providing important insights into preventative as well as response-based actions designed to positively impact health outcomes. The material is presented in 29 chapters and brings together the research and work of an international team of experts. designed to bridge the gap between traditional approaches to dietary interventions and leading edge integrated health strategies, Handbook of Lipids in Human Function: Fatty Acids is a valuable resource for researchers and clinicians.