Glycopolymers

Glycopolymers PDF Author: Ravin Narain
Publisher: Smithers Rapra
ISBN: 1909030821
Category : Medical
Languages : en
Pages : 180

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Book Description
Glycopolymers have received considerable interest in recent years due to their increasing potential applications in material science and biomedicine. With better understanding of the role of carbohydrates in biological systems and with recent advances in organic and carbohydrate chemistry, the design and synthesis of glycopolymers have become simpler where significant research efforts have been carried out towards the fabrication of advanced glyco-polymeric architectures for improved performance. This book provides an update on the recent advances on the synthesis of glycopolymers, their characterisations, their biological properties and their applications. The first objective of this book is to provide the readers a detailed overview about the synthesis of glycopolymers via several modern polymerisation techniques. The characterisation of these materials and their solution properties are also discussed. In addition to this, the conjugation of glycopolymers to different types of biomacromolecules are discussed. The second objective of this book is to provide a detailed overview of the applications of glycopolymers. In addition, the biological properties of the glycopolymers as a function of the types of carbohydrates attached, the polymer architectures and compositions are elaborated. This book will provide a quick reference to students and researchers working in both academia and industry.

Glycopolymers

Glycopolymers PDF Author: Ravin Narain
Publisher: Smithers Rapra
ISBN: 1909030821
Category : Medical
Languages : en
Pages : 180

Get Book Here

Book Description
Glycopolymers have received considerable interest in recent years due to their increasing potential applications in material science and biomedicine. With better understanding of the role of carbohydrates in biological systems and with recent advances in organic and carbohydrate chemistry, the design and synthesis of glycopolymers have become simpler where significant research efforts have been carried out towards the fabrication of advanced glyco-polymeric architectures for improved performance. This book provides an update on the recent advances on the synthesis of glycopolymers, their characterisations, their biological properties and their applications. The first objective of this book is to provide the readers a detailed overview about the synthesis of glycopolymers via several modern polymerisation techniques. The characterisation of these materials and their solution properties are also discussed. In addition to this, the conjugation of glycopolymers to different types of biomacromolecules are discussed. The second objective of this book is to provide a detailed overview of the applications of glycopolymers. In addition, the biological properties of the glycopolymers as a function of the types of carbohydrates attached, the polymer architectures and compositions are elaborated. This book will provide a quick reference to students and researchers working in both academia and industry.

Glycopolymers Polyelectrolyte Multilayers for Biomedical Applications

Glycopolymers Polyelectrolyte Multilayers for Biomedical Applications PDF Author:
Publisher: Scholar Press
ISBN: 6202306238
Category :
Languages : en
Pages : 268

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Book Description
The theoretical background of this work is concerning with the drug loaded polyelectrolyte multilayers (PEM) modified by the host-guest interaction of biocompatible hyperbranched core-shell glycopolymers. The glycopolymer in this work is the hyperbranched polyethyleneimine that was modified with maltose moieties using reductive amination. Thus, the use of glycohyperbranched polymers for drug delivery would allow the avoid naturally occurring drug resistance due to decreased transporter activity. Concerning preparative method, PEM was fabricated using layer-by-layer (LbL) processes involve the sequential deposition of two polyions that physically bond together. Control was taken on the stoichiometric ratio related to cationic and anionic repeating units, which was chosen close to zero for the final applied PEM. Concerning analytical methods, a couple of physical-chemical methods were applied to characterize colloid stability, adhesiveness, drug loading and release of fabricated PEM. In conclusion, a highly sable and sustainable PEM coats on a surface of an activated solid substrate has been fabricated with an efficient ability to recycle the charged molecule for more than 24 times.

Glycopolymer Code

Glycopolymer Code PDF Author: C. Remzi Becer
Publisher: Royal Society of Chemistry
ISBN: 1782624686
Category : Science
Languages : en
Pages : 251

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Book Description
Glycopolymers are important for cell signalling, recognition pathways, and their role in the immune system. They are gaining attention for new applications in tissue engineering and drug delivery. Glycopolymer Code discusses the preparation, characterization and applications of glycopolymers providing a complete overview of the topic with examples from the latest research. Specific chapters cover both basic and advanced synthesis techniques to prepare glycopolymers, the analytical techniques used to investigate lectin receptor glycopolymer interactions, the properties and types of lectins that are widely used to understand the multivalent interactions and various applications of synthetic glycopolymers. With contributions from leading researchers in the field, the book is a unique source for graduates and academics new to the subject and already working in the area of glycopolymers.

Engineered Carbohydrate-Based Materials for Biomedical Applications

Engineered Carbohydrate-Based Materials for Biomedical Applications PDF Author: Ravin Narain
Publisher: John Wiley & Sons
ISBN: 1118002245
Category : Technology & Engineering
Languages : en
Pages : 416

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Book Description
This book addresses the need for a comprehensive book on the design, synthesis, and characterization of synthetic carbohydrate-based polymeric materials along with their biological applications. The first two chapters cover the synthesis and self-assembly of glycopolymers and different techniques for creating these synthetic polymers. Subsequent chapters account for the preparation of block copolymers, branched glycopolymers, glycosurfaces, glycodendrimers, cationic glycopolymers, bioconjugates, glyconanoparticles and hydrogels. While these chapters comprehensively review the synthetic and characterization methods of those carbohydrate-based materials, their biological applications are discussed in detail.

Glycoscience: Basic Science to Applications

Glycoscience: Basic Science to Applications PDF Author: Naoyuki Taniguchi
Publisher: Springer Nature
ISBN: 9811358567
Category : Medical
Languages : en
Pages : 405

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Book Description
This book presents the state of the art in glycoscience and proposes a road map for the coming decade, focusing on the potential of glycoscience research to shed light on important basic science issues and give rise to exciting new applications, especially in the field of diagnosis and therapeutics. Individual sections offer in-depth coverage of various topics relating to glycans and biopharmaceuticals, glycans in medical science and medicine, glycan technologies, glycans in food and nutrients, and glycan-related materials and their uses. In addition, the book presents an exemplary training course on glycomics and highlights educational and analytical web resources, and also includes glossaries and boxes summarizing key facts to ensure ease of understanding for non-expert readers and students. Written by more than 150 active participants in the Japan Consortium for Glycobiology and Glycotechnology (JCGG), whose goal is to promote the development of interdisciplinary glycoscience and establish a global network in the field, it is a valuable resource for students, postdocs, and researchers in the life sciences as well as for stakeholders and professionals in government, funding agencies and industry.

Biomaterials Nanoarchitectonics

Biomaterials Nanoarchitectonics PDF Author: Mitsuhiro Ebara
Publisher: William Andrew
ISBN: 0323374999
Category : Technology & Engineering
Languages : en
Pages : 364

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Book Description
Biomaterials Nanoarchitectonics, written from the perspectives of authors form NIMS and other researchers worldwide, provides readers with an explanation of the theory and techniques of nanoarchitectonics, exploring its applications in biomedical fields, including regenerative medicine, drug delivery, and diagnostic and treatment systems based on pathogenic mechanisms. The book also explains the use of nanomaterials that enable 'materials therapy', in which the materials themselves elicit a sustainable, curative effect from living tissue. Authored by the team that coined the term nanoarchitectonics, who explain their approach to the design of smart/functional nanomaterials and their applications in the biomedical arena Explores how materials designed and produced with nanoarchitectonics methods can be used to enhance the natural regenerative power of the human body Enables scientists and researchers to gain a deeper understanding of the specific challenges of materials design at the nanoscale

Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems

Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems PDF Author: Mohammed Zourob
Publisher: Springer Science & Business Media
ISBN: 0387751130
Category : Technology & Engineering
Languages : en
Pages : 980

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Book Description
Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems will cover the up-to-date biosensor technologies used for the detection of bacteria. Written by the world's most renowned and learned scientists each in their own area of expertise, Principles of Bacterial Detection: Biosensors, Recognition Receptors and Microsystems is the first title to cover this expanding research field.

Engineering of Biomaterials for Drug Delivery Systems

Engineering of Biomaterials for Drug Delivery Systems PDF Author: Anilkumar Parambath
Publisher: Woodhead Publishing
ISBN: 0081017510
Category : Technology & Engineering
Languages : en
Pages : 405

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Book Description
Engineering of Biomaterials for Drug Delivery Systems: Beyond Polyethylene Glycol examines the combined issues of PEGylation and viable biomaterials as alternatives. With a strong focus on polymeric biomaterials, the book first reviews the major issues associated with PEGylation and its use in vivo. Chapters then focus on alternative polymer systems for drug delivery systems. Finally, nanoparticles and future perspectives are examined. This book is a valuable resource for scientists and researchers in biomaterials, pharmaceuticals and nanotechnology, and all those who wish to broaden their knowledge in this field. Provides a self-contained work for the field of biomaterials for drug delivery Summarizes the current knowledge on PEGylation and strategies for bypassing it Presents research on an important, though under-represented issue in biomaterials Written by a world-class team of research scientists, engineers and clinicians

Polymer Adhesion, Friction, and Lubrication

Polymer Adhesion, Friction, and Lubrication PDF Author: Hongbo Zeng
Publisher: John Wiley & Sons
ISBN: 1118505131
Category : Technology & Engineering
Languages : en
Pages : 534

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Book Description
Specifically dedicated to polymer and biopolymer systems, Polymer Adhesion, Friction, and Lubrication guides readers to the scratch, wear, and lubrication properties of polymers and the engineering applications, from biomedical research to automotive engineering. Author Hongbo Zeng details different experimental and theoretical methods used to probe static and dynamic properties of polymer materials and biomacromolecular systems. Topics include the use of atomic force microscopy (AFM) to analyze nanotribology, polymer thin films and brushes, nanoparticles, rubber and tire technology, synovial joint lubrication, adhesion in paper products, bioMEMS, and electrorheological fluids.

Click Chemistry in Glycoscience

Click Chemistry in Glycoscience PDF Author: Zbigniew J. Witczak
Publisher: John Wiley & Sons
ISBN: 1118275330
Category : Science
Languages : en
Pages : 402

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Book Description
Lays the foundation for new methods and applications of carbohydrate click chemistry Introduced by K. Barry Sharpless of The Scripps Research Institute in 2001, click chemistry mimics nature, giving researchers the tools needed to generate new substances quickly and reliably by joining small units together. With contributions from more than thirty pioneering researchers in the field, this text explores the many promising applications of click chemistry in glycoscience. Readers will learn both the basic concepts of carbohydrate click chemistry as well as its many biomedical applications, including synthetic antigens, analogs of cell-surface receptors, immobilized enzymes, targeted drug delivery systems, and multivalent cancer vaccines. Click Chemistry in Glycoscience examines a broad range of methodologies and strategies that have emerged from this rapidly evolving field. Each chapter describes new approaches, ideas, consequences, and applications resulting from the introduction of click processes. Divided into four sections, the book covers: Click chemistry strategies and decoupling Thio-click chemistry of carbohydrates Carbohydrate click chemistry for novel synthetic targets Carbohydrate click chemistry in biomedical sciences Thoroughly researched, the book reflects the most recent findings published in the literature. Diagrams and figures throughout the book enable readers to more easily grasp complex concepts and reaction processes. At the end of each chapter, references lead to the primary literature for further investigation of individual topics. The application of click chemistry to carbohydrates has tremendous implications for research. With this book as their guide, researchers have a solid foundation from which they can develop new methods and applications of carbohydrate click chemistry, including new carbohydrate-based therapeutics.