Glycobiology of the Nervous System PDF Download
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Author: Robert K. Yu
Publisher: Springer
ISBN: 1493911546
Category : Medical
Languages : en
Pages : 590
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Book Description
A thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.
Author: Robert K. Yu
Publisher: Springer
ISBN: 1493911546
Category : Medical
Languages : en
Pages : 590
Get Book Here
Book Description
A thorough introduction is provided to the variety and complexity of the roles that glycoconjugates play in the cells of the nervous system. Basic information as well as the latest developments in neural glycobiology are discussed. Topics covered range from the structure and metabolism of the saccharide chains and current approaches used in their study, to changes glycoconjugates undergo during development and aging of the nervous system and the roles they have in neurological disease. The breadth and depth of topics covered make it an essential reference for those new to the field as well more seasoned investigators.
Author: Minoru Fukuda
Publisher: Oxford University Press, USA
ISBN: 9780198525387
Category : Language Arts & Disciplines
Languages : en
Pages : 272
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Book Description
Carbohydrates play a major role in brain function. In the past decade, tremendous progress has been made in understanding their structure and function within the nervous system. This book presents a state of the art account of this rapidly expanding field.
Author: Ajit Varki
Publisher: CSHL Press
ISBN: 9780879696818
Category : Medical
Languages : en
Pages : 694
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Book Description
Sugar chains (glycans) are often attached to proteins and lipids and have multiple roles in the organization and function of all organisms. "Essentials of Glycobiology" describes their biogenesis and function and offers a useful gateway to the understanding of glycans.
Author: Minoru Fukuda
Publisher:
ISBN: 9780191723872
Category : Brain
Languages : en
Pages : 229
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Book Description
Carbohydrates play a major role in brain function. In the past decade, tremendous progress has been made in understanding their structure and function within the nervous system. This book presents a state of the art account of this rapidly expanding field.
Author: Howard J. Allen
Publisher: CRC Press
ISBN: 9780824784317
Category : Medical
Languages : en
Pages : 704
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Book Description
Glycoconjugates Composition: Structure, and Function provides an excellent overview of the composition, biosynthesis, function and structure of the carbohydrate chains of glycoconjugates from higher organisms. It is recommended as a core reference text, providing excellent coverage of the glycoconjugate field.
Author: M. Nicolini
Publisher: Pergamon
ISBN:
Category : Medical
Languages : en
Pages : 314
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Book Description
This book draws together for the first time contributions from carbohydrate research in the areas of neurobiology, neuropathology, and neuropharmacology, highlighting the importance of carbohydrates in the understanding of neurobiology, the development of neuropathology and the commercialisation of neuropharmacological agents. Glycobiology is a relatively new field emerging in importance both in research institutes and industry. The chapters in this book focus on aspects of the present and future application of the study of glycobiology to brain biochemistry, from basic research on glycoconjugates to practical identification of carbohydrates in neuropathological studies and the relevance of structural studies in a pharmacological perspective.
Author: Gordan Lauc
Publisher: Springer Nature
ISBN: 3030701158
Category : Science
Languages : en
Pages : 392
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Book Description
Glycobiology is an emerging field of studying glycans (sugars) and glycoconjugates that are essentially involved in almost all biological processes, from fine-tuning glycoprotein function to protein-protein interactions, signaling, immune response, host-pathogen interactions, etc. However, due to structural complexity of glycans and analytical challenges this exciting field was lagging behind other areas of biology. With technological advancements growing number of glycans’ functions are being discovered and the study of glycans is becoming a cutting-edge discipline in basic and clinical research. Despite recent developments in glycobiology field, many aspects of glycosylation process still remain unknown, both in a healthy human organism and in pathological states. Human glycome is dynamic and changes with physiological triggers, immune challenges and disease. Atypical glycosylation is consequently a subject of disease biomarker research, and a target for therapeutic interventions. On the other hand, properties of glycosylated biotherapeutics are predominantly determined by their glycans. The Role of Glycosylation in Health and Disease provides a comprehensive overview of types and functions of glycans in a healthy human organism as well as their role in pathophysiology of different diseases and efficiency of glycosylated biotherapeutics. Written by the experts in the field, this book aims to bring glycobiology field closer to students, researchers in life sciences and professionals in biopharmaceutical industry.
Author: Maarten E. A. Reith
Publisher: Springer Science & Business Media
ISBN:
Category : Medical
Languages : en
Pages : 540
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Book Description
Neurotransmission is a multicomponent process. Transmitters, released by neuronal activity, act on pre- and postsynaptic receptors, and many books detail advances in the receptor field. In addition, after their release from nerve endings, transmitters are removed from the neuronal vicinity by uptake into neuronal or glial cells by specific tra- porter proteins that have been studied intensely over the last 30 years; this information is scattered throughout numerous publishing vehicles. Therefore, the primary aim of this second edition of N- rotransmitter Transporters: Structure, Function, and Regulation is to offer a comprehensive picture of the characterization of neurotransmitter transporters and their biological roles. The transporter field has moved forward in stages. In the first phase, progress came from the use of substrate or blocker ligands selectively targeting transporters, the application of model systems allowing the study of transmitter tra- port shielded from storage, and the development of mathematical models for describing transport phenomena. In the second phase, roughly covering the last decade, advances in DNA techniques allowed the cloning of numerous genes coding for different transporter proteins. In the current, third stage, a wealth of information is being accumulated in studies relating transporter structure with function, experiments addressing regulation by posttranslational transfor- tion, investigations into transport modulation by trafficking processes and genomic influences, characterization of channel properties of tra- porters by electrophysiological approaches, and the creation of transgenic animals under- or overexpressing a given transporter protein.
Author: Hans-Joachim Gabius
Publisher: John Wiley & Sons
ISBN: 3527644946
Category : Science
Languages : en
Pages : 560
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Book Description
A reader friendly overview of the structure and functional relevance of natural glycosylation and its cognate proteins (lectins), this book is also one of the few books to cover their role in health and disease. Edited by one of the pioneering experts in the field and written by a team of renowned researchers this resource is a perfect introduction for all students in life and medical sciences, biochemistry, chemistry and pharmacy. Website: WWW.WILEY-VCH.DE/HOME/THESUGARCODE
Author: Naoyuki Taniguchi
Publisher: Springer
ISBN: 9789811358555
Category : Medical
Languages : en
Pages : 405
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Book Description
This book presents the state of the art in glycoscience and proposes a road map for the coming decade, focusing on the potential of glycoscience research to shed light on important basic science issues and give rise to exciting new applications, especially in the field of diagnosis and therapeutics. Individual sections offer in-depth coverage of various topics relating to glycans and biopharmaceuticals, glycans in medical science and medicine, glycan technologies, glycans in food and nutrients, and glycan-related materials and their uses. In addition, the book presents an exemplary training course on glycomics and highlights educational and analytical web resources, and also includes glossaries and boxes summarizing key facts to ensure ease of understanding for non-expert readers and students. Written by more than 150 active participants in the Japan Consortium for Glycobiology and Glycotechnology (JCGG), whose goal is to promote the development of interdisciplinary glycoscience and establish a global network in the field, it is a valuable resource for students, postdocs, and researchers in the life sciences as well as for stakeholders and professionals in government, funding agencies and industry.
