Paleogenomics

Paleogenomics PDF Author: Charlotte Lindqvist
Publisher: Springer
ISBN: 3030047539
Category : Science
Languages : en
Pages : 432

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Book Description
Advances in genome-scale DNA sequencing technologies have revolutionized genetic research on ancient organisms, extinct species, and past environments. When it is recoverable after hundreds or thousands of years of unintended preservation, “ancient DNA” (or aDNA) is often highly degraded, necessitating specialized handling and analytical approaches. Paleogenomics defines the field of reconstructing and analyzing the genomes of historic or long-dead organisms, most often through comparison with modern representatives of the same or similar species. The opportunity to isolate and study paleogenomes has radically transformed many fields, spanning biology, anthropology, agriculture, and medicine. Examples include understanding evolutionary relationships of extinct species known only from fossils, the domestication of plants and animals, and the evolution and geographical spread of certain pathogens. This pioneering book presents a snapshot view of the history, current status, and future prospects of paleogenomics, taking a broad viewpoint that covers a range of topics and organisms to provide an up-to-date status of the applications, challenges, and promise of the field. This book is intended for a variety of readerships, including upper-level undergraduate and graduate students, professionals and experts in the field, as well as anyone excited by the extraordinary insights that paleogenomics offers.

Paleogenomics

Paleogenomics PDF Author: Charlotte Lindqvist
Publisher: Springer
ISBN: 3030047539
Category : Science
Languages : en
Pages : 432

Get Book Here

Book Description
Advances in genome-scale DNA sequencing technologies have revolutionized genetic research on ancient organisms, extinct species, and past environments. When it is recoverable after hundreds or thousands of years of unintended preservation, “ancient DNA” (or aDNA) is often highly degraded, necessitating specialized handling and analytical approaches. Paleogenomics defines the field of reconstructing and analyzing the genomes of historic or long-dead organisms, most often through comparison with modern representatives of the same or similar species. The opportunity to isolate and study paleogenomes has radically transformed many fields, spanning biology, anthropology, agriculture, and medicine. Examples include understanding evolutionary relationships of extinct species known only from fossils, the domestication of plants and animals, and the evolution and geographical spread of certain pathogens. This pioneering book presents a snapshot view of the history, current status, and future prospects of paleogenomics, taking a broad viewpoint that covers a range of topics and organisms to provide an up-to-date status of the applications, challenges, and promise of the field. This book is intended for a variety of readerships, including upper-level undergraduate and graduate students, professionals and experts in the field, as well as anyone excited by the extraordinary insights that paleogenomics offers.

The Pivot

The Pivot PDF Author: Robert J. Bliwise
Publisher: Duke University Press
ISBN: 1478023759
Category : Education
Languages : en
Pages : 234

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Book Description
The COVID-19 pandemic presented higher education with an unprecedented challenge: How could institutions continue the basic work of teaching and research while maintaining safe environments for their faculty, staff, and students? In The Pivot, Robert J. Bliwise traces Duke University’s response to the pandemic to show how higher education broadly met that challenge head-on. Bliwise interviews people across the campus: from bus drivers and vaccine researchers to student activists, dining hall managers, and professors in areas from English to ecology. He explores the shift to teaching online and the reshaping of research programs; how surveillance testing and reconfiguring residence halls and dining sites helped limit the virus spread on campus; the efforts to promote student well-being and to sustain extracurricular programs; and what the surge in COVID-19 cases meant for the university health system. Bliwise also shows how broad cultural conversations surrounding the 2020 presidential election, climate change, free speech on campus, and systemic racism unfolded in this changed campus environment. Although the pandemic put remarkable pressures on the campus community, Bliwise demonstrates that it ultimately reaffirmed the importance of the campus experience in all its richness and complexity.

Quaternary Glaciations - Extent and Chronology

Quaternary Glaciations - Extent and Chronology PDF Author: J. Ehlers
Publisher: Elsevier
ISBN: 0444534474
Category : Science
Languages : en
Pages : 1128

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Book Description
The book presents an up-to-date, detailed overview of the Quaternary glaciations all over the world, not only with regard to stratigraphy but also with regard to major glacial landforms and the extent of the respective ice sheets. The locations of key sites are included. The information is presented in digital, uniformly prepared maps which can be used in a Geographical Information System (GIS) such as ArcView or ArcGIS. The accompanying text supplies the information on how the data were obtained (geomorphology, geological mapping, air photograph evaluation, satellite imagery), how the features were dated (14C, TL, relative stratigraphy) and how reliable they are supposed to be. All references to the underlying basic publications are included. Where controversial interpretations are possible e.g. in Siberia or Tibet, this is pointed out. As a result, the information on Quaternary glaciations worldwide will be much improved and supplied in a uniform digital format. The information on the glacial limits is compiled in digital form by the coordinators of the project, and is available for download at: http://booksite.elsevier.com/9780444534477/ Completely updated detailed coverage of worldwide Quaternary glaciations Information in digital, uniformly prepared maps which can be used in a GIS such as ArcView or ArcGis Step-by-step guideline how to open and use ArcGis files Possibility to convert the shapefiles into GoogleEarth kmz-files Availability of chronological controls

DNA Methods in Food Safety

DNA Methods in Food Safety PDF Author: Omar A. Oyarzabal
Publisher: John Wiley & Sons
ISBN: 1118278658
Category : Technology & Engineering
Languages : en
Pages : 357

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Book Description
Molecular typing of foodborne pathogens has become an indispensable tool in epidemiological studies. Thanks to these techniques, we now have a better understanding of the distribution and appearance of bacterial foodborne diseases and have a deeper knowledge of the type of food products associated with the major foodborne pathogens. Within the molecular techniques, DNA-based techniques have prospered for more than 40 years and have been incorporated in the first surveillance systems to monitor bacterial foodborne pathogens in the United States and other countries. However, DNA techniques vary widely and many microbiology laboratory personnel working with food and/or water face the dilemma of which method to incorporate. DNA Methods in Food Safety: Molecular Typing of Foodborne and Waterborne Bacterial Pathogens succinctly reviews more than 25 years of data on a variety of DNA typing techniques, summarizing the different mathematical models for analysis and interpretation of results, and detailing their efficacy in typing different foodborne and waterborne bacterial pathogens, such as Campylobacter, Clostridium perfringens, Listeria, Salmonella, among others. Section I describes the different DNA techniques used in the typing of bacterial foodborne pathogens, whilst Section II deals with the application of these techniques to type the most important bacterial foodborne pathogens. In Section II the emphasis is placed on the pathogen, and each chapter describes some of the most appropriate techniques for typing each bacterial pathogen. The techniques presented in this book are the most significant in the study of the molecular epidemiology of bacterial foodborne pathogens to date. It therefore provides a unique reference for students and professionals in the field of microbiology, food and water safety and epidemiology and molecular epidemiology.

The Great American Biotic Interchange

The Great American Biotic Interchange PDF Author: Alberto Luis Cione
Publisher: Springer
ISBN: 9401797927
Category : Science
Languages : en
Pages : 106

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Book Description
South American ecosystems suffered one of the greatest biogeographical events, after the establishment of the Panamian land bridge, called the “Great American Biotic Interchange” (GABI). This refers to the exchange, in several phases, of land mammals between the Americas; this event started during the late Miocene with the appearance of the Holartic Procyonidae (Huayquerian Age) in South America and continues today. The major phases of mammalian dispersal occurred from the Latest Pliocene (Marplatan Age) to the Late Pleistocene (Lujanian Age). The most important and richest localities of Late Miocene-Holocene fossil vertebrates of South America are those of the Pampean region of Argentina. There are also several Late Miocene and Pliocene localities in western Argentina and Bolivia. Other important fossils have been collected in localities of Pleistocene age outside Argentina: Tarija (Bolivia), karstic caves of Lagoa Santa and the recently explored caves of Tocantins (Brasil), Talara (Perú), La Carolina (Ecuador), Muaco (Venezuela), and Cueva del Milodon (Chile), among others. The book discusses basic information for interpreting the GABI such as taxonomic composition (incorporating the latest revisions) at classical and new localities for each stage addressing climate, environments, and time boundaries for each stage. It includes the chronology and dynamics of the GABI, the integration of South American mammalian faunas through time, the Quaternary mammalian extinctions and the composition of recent mammalian fauna of the continent.

Dynamic Systems Biology Modeling and Simulation

Dynamic Systems Biology Modeling and Simulation PDF Author: Joseph DiStefano III
Publisher: Academic Press
ISBN: 0124104932
Category : Science
Languages : en
Pages : 886

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Book Description
Dynamic Systems Biology Modeling and Simuation consolidates and unifies classical and contemporary multiscale methodologies for mathematical modeling and computer simulation of dynamic biological systems – from molecular/cellular, organ-system, on up to population levels. The book pedagogy is developed as a well-annotated, systematic tutorial – with clearly spelled-out and unified nomenclature – derived from the author's own modeling efforts, publications and teaching over half a century. Ambiguities in some concepts and tools are clarified and others are rendered more accessible and practical. The latter include novel qualitative theory and methodologies for recognizing dynamical signatures in data using structural (multicompartmental and network) models and graph theory; and analyzing structural and measurement (data) models for quantification feasibility. The level is basic-to-intermediate, with much emphasis on biomodeling from real biodata, for use in real applications. - Introductory coverage of core mathematical concepts such as linear and nonlinear differential and difference equations, Laplace transforms, linear algebra, probability, statistics and stochastics topics - The pertinent biology, biochemistry, biophysics or pharmacology for modeling are provided, to support understanding the amalgam of "math modeling with life sciences - Strong emphasis on quantifying as well as building and analyzing biomodels: includes methodology and computational tools for parameter identifiability and sensitivity analysis; parameter estimation from real data; model distinguishability and simplification; and practical bioexperiment design and optimization - Companion website provides solutions and program code for examples and exercises using Matlab, Simulink, VisSim, SimBiology, SAAMII, AMIGO, Copasi and SBML-coded models - A full set of PowerPoint slides are available from the author for teaching from his textbook. He uses them to teach a 10 week quarter upper division course at UCLA, which meets twice a week, so there are 20 lectures. They can easily be augmented or stretched for a 15 week semester course - Importantly, the slides are editable, so they can be readily adapted to a lecturer's personal style and course content needs. The lectures are based on excerpts from 12 of the first 13 chapters of DSBMS. They are designed to highlight the key course material, as a study guide and structure for students following the full text content - The complete PowerPoint slide package (~25 MB) can be obtained by instructors (or prospective instructors) by emailing the author directly, at: [email protected]

Biological Systematics

Biological Systematics PDF Author: Andrew V. Z. Brower
Publisher: Cornell University Press
ISBN: 1501752782
Category : Science
Languages : en
Pages : 424

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Book Description
Understanding the history and philosophy of biological systematics (phylogenetics, taxonomy and classification of living things) is key to successful practice of the discipline. In this thoroughly revised Third Edition of the classic Biological Systematics, Andrew V. Z. Brower and Randall T. Schuh provide an updated account of cladistic principles and techniques, emphasizing their empirical and epistemological clarity. Brower and Schuh cover: -the history and philosophy of systematics -the mechanics and methods of character analysis, phylogenetic inference, and evaluation of results -the practical application of systematic results to: -biological classification -adaptation and coevolution -biodiversity, and conservation -new chapters on species and molecular clocks Biological Systematics is both a textbook for students studying systematic biology and a desk reference for practicing systematists. Part explication of concepts and methods, part exploration of the underlying epistemology of systematics, This third edition addresses why some methods are more empirically sound than others.

Lizards of Patagonia

Lizards of Patagonia PDF Author: Mariana Morando
Publisher: Springer Nature
ISBN: 3030427528
Category : Science
Languages : en
Pages : 444

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Book Description
This book presents a critical and integrated review of lizards from Patagonia. It summarizes the region’s geomorphological history and climatic aspects, which makes it possible to interpret, from an evolutionary perspective, the latest findings on the various natural history aspects of its lizard fauna. As such, the book will appeal to all researchers and professionals specialized in lizard ecology and evolution.

Jigo Jitoku

Jigo Jitoku PDF Author: M. Christian
Publisher: Wildside Press LLC
ISBN: 1479465836
Category : Fiction
Languages : en
Pages : 20

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Book Description
If you look too long into the abyss of cyberspace, it may look back at you. A classic cyberpunk tale!

Neotropical Diversification: Patterns and Processes

Neotropical Diversification: Patterns and Processes PDF Author: Valentí Rull
Publisher: Springer Nature
ISBN: 3030311678
Category : Science
Languages : en
Pages : 816

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Book Description
This book provides a comprehensive overview of the patterns of biodiversity in various neotropical ecosystems, as well as a discussion on their historical biogeographies and underlying diversification processes. All chapters were written by prominent researchers in the fields of tropical biology, molecular ecology, climatology, paleoecology, and geography, producing an outstanding collection of essays, synthetic analyses, and novel investigations that describe and improve our understanding of the biodiversity of this unique region. With chapters on the Amazon and Caribbean forests, the Atlantic rainforests, the Andes, the Cerrado savannahs, the Caatinga drylands, the Chaco, and Mesoamerica – along with broad taxonomic coverage – this book summarizes a wide range of hypotheses, views, and methods concerning the processes and mechanisms of neotropical diversification. The range of perspectives presented makes the book a truly comprehensive, state-of-the-art publication on the topic, which will fascinate both scientists and general readers alike.