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Author: Catherine Vacher
Publisher: John Wiley & Sons
ISBN: 1119573408
Category : Science
Languages : en
Pages : 360
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Book Description
Perform genome analysis and sequencing of data with Amazon Web Services Genomics in the AWS Cloud: Analyzing Genetic Code Using Amazon Web Services enables a person who has moderate familiarity with AWS Cloud to perform full genome analysis and research. Using the information in this book, you'll be able to take a FASTQ file containing raw data from a lab or a BAM file from a service provider and perform genome analysis on it. You'll also be able to identify potentially pathogenic gene sequences. Get an introduction to Whole Genome Sequencing (WGS) Make sense of WGS on AWS Master AWS services for genome analysis Some key advantages of using AWS for genomic analysis is to help researchers utilize a wide choice of compute services that can process diverse datasets in analysis pipelines. Genomic sequencers that generate raw data files are located in labs on premises and AWS provides solutions to make it easy for customers to transfer these files to AWS reliably and securely. Storing Genomics and Medical (e.g., imaging) data at different stages requires enormous storage in a cost-effective manner. Amazon Simple Storage Service (Amazon S3), Amazon Glacier, and Amazon Elastics Block Store (Amazon EBS) provide the necessary solutions to securely store, manage, and scale genomic file storage. Moreover, the storage services can interface with various compute services from AWS to process these files. Whether you're just getting started or have already been analyzing genomics data using the AWS Cloud, this book provides you with the information you need in order to use AWS services and features in the ways that will make the most sense for your genomic research.
Author: Catherine Vacher
Publisher: John Wiley & Sons
ISBN: 1119573408
Category : Science
Languages : en
Pages : 360
Get Book Here
Book Description
Perform genome analysis and sequencing of data with Amazon Web Services Genomics in the AWS Cloud: Analyzing Genetic Code Using Amazon Web Services enables a person who has moderate familiarity with AWS Cloud to perform full genome analysis and research. Using the information in this book, you'll be able to take a FASTQ file containing raw data from a lab or a BAM file from a service provider and perform genome analysis on it. You'll also be able to identify potentially pathogenic gene sequences. Get an introduction to Whole Genome Sequencing (WGS) Make sense of WGS on AWS Master AWS services for genome analysis Some key advantages of using AWS for genomic analysis is to help researchers utilize a wide choice of compute services that can process diverse datasets in analysis pipelines. Genomic sequencers that generate raw data files are located in labs on premises and AWS provides solutions to make it easy for customers to transfer these files to AWS reliably and securely. Storing Genomics and Medical (e.g., imaging) data at different stages requires enormous storage in a cost-effective manner. Amazon Simple Storage Service (Amazon S3), Amazon Glacier, and Amazon Elastics Block Store (Amazon EBS) provide the necessary solutions to securely store, manage, and scale genomic file storage. Moreover, the storage services can interface with various compute services from AWS to process these files. Whether you're just getting started or have already been analyzing genomics data using the AWS Cloud, this book provides you with the information you need in order to use AWS services and features in the ways that will make the most sense for your genomic research.
Author: Sizwe Molefe
Publisher: BPB Publications
ISBN: 9365899753
Category : Computers
Languages : en
Pages : 396
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Book Description
DESCRIPTION Cloud computing provides a more efficient, reliable, secure, and cost-effective way to run applications. Cloud computing offers customers access to rapidly growing amounts of data storage and computation resources while centralizing IT operations in the cloud provider's datacenter or in colocation data centers. Understand AWS basics such as EC2, VPCs, S3, and IAM while learning to design secure and scalable cloud architectures. This book guides you through automating infrastructure with CloudFormation and exploring advanced topics like containers, continuous integration and continuous delivery (CI/CD) pipelines, and cloud migration. You will also discover serverless computing with Lambda, API Gateway, and DynamoDB, enabling you to build efficient, modern applications. With real-world examples and best practices, this resource helps you optimize your AWS environment for both performance and cost, ensuring you can build and maintain robust cloud solutions. By the end of this book, you will be able to confidently design, build, and operate scalable and secure cloud solutions on AWS. Gain the expertise to leverage the full potential of cloud computing and drive innovation in your organization. KEY FEATURES ● Learn about AWS cloud in-depth with real-world examples and scenarios. ● Expand your understanding of serverless and containerization compute technology on AWS. ● Explore API’s along with API Gateway and its different use cases. WHAT YOU WILL LEARN ● How to get started with and launch EC2 instances. ● Working with and simplifying VPC’s, security groups, and network access control lists on AWS. ● Learn how to secure your AWS environment through the use of IAM roles and policies. ● Learn how to build scalable and fault-tolerant database systems using AWS database services such as RDS and Aurora. ● Learn how to set up a CI/CD pipeline on AWS. WHO THIS BOOK IS FOR Whether you are a system administrator, cloud architect, solutions architect, cloud engineer, DevOps engineer, security engineer, or cloud professional, this book provides valuable insights and practical guidance to help you build and operate robust cloud solutions on AWS. TABLE OF CONTENTS 1. Creating an AWS Environment 2. Amazon Elastic Compute Cloud 3. Amazon Virtual Private Cloud 4. Amazon S3: Simple Storage Service 5. Amazon API Gateway 6. AWS Database Services 7. Elastic Load Balancing and Auto Scaling 8. Amazon Route 53 9. Decouple Applications 10. CloudFormation 11. AWS Monitoring 12. AWS Security and Encryption 13. AWS Containers 14. Automating Deployments with CI/CD in AWS 15. AWS Cloud Migrations
Author: Diego A. Forero
Publisher: CRC Press
ISBN: 1000405672
Category : Science
Languages : en
Pages : 374
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Book Description
Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.
Author: Mani Khanuja
Publisher: Packt Publishing Ltd
ISBN: 1803244445
Category : Computers
Languages : en
Pages : 382
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Book Description
Build, train, and deploy large machine learning models at scale in various domains such as computational fluid dynamics, genomics, autonomous vehicles, and numerical optimization using Amazon SageMaker Key FeaturesUnderstand the need for high-performance computing (HPC)Build, train, and deploy large ML models with billions of parameters using Amazon SageMakerLearn best practices and architectures for implementing ML at scale using HPCBook Description Machine learning (ML) and high-performance computing (HPC) on AWS run compute-intensive workloads across industries and emerging applications. Its use cases can be linked to various verticals, such as computational fluid dynamics (CFD), genomics, and autonomous vehicles. This book provides end-to-end guidance, starting with HPC concepts for storage and networking. It then progresses to working examples on how to process large datasets using SageMaker Studio and EMR. Next, you'll learn how to build, train, and deploy large models using distributed training. Later chapters also guide you through deploying models to edge devices using SageMaker and IoT Greengrass, and performance optimization of ML models, for low latency use cases. By the end of this book, you'll be able to build, train, and deploy your own large-scale ML application, using HPC on AWS, following industry best practices and addressing the key pain points encountered in the application life cycle. What you will learnExplore data management, storage, and fast networking for HPC applicationsFocus on the analysis and visualization of a large volume of data using SparkTrain visual transformer models using SageMaker distributed trainingDeploy and manage ML models at scale on the cloud and at the edgeGet to grips with performance optimization of ML models for low latency workloadsApply HPC to industry domains such as CFD, genomics, AV, and optimizationWho this book is for The book begins with HPC concepts, however, it expects you to have prior machine learning knowledge. This book is for ML engineers and data scientists interested in learning advanced topics on using large datasets for training large models using distributed training concepts on AWS, deploying models at scale, and performance optimization for low latency use cases. Practitioners in fields such as numerical optimization, computation fluid dynamics, autonomous vehicles, and genomics, who require HPC for applying ML models to applications at scale will also find the book useful.
Author: Hilde Stevens
Publisher: Frontiers Media SA
ISBN: 2889639452
Category :
Languages : en
Pages : 107
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Book Description
Multi-stakeholder collaborations involving partners from public and private sectors are essential to address global health challenges and to move precision medicine forward. This eBook assembles a collection of papers which either illustrate recent achievements or discuss new perspectives offered by public-private partnerships in healthcare. Publisher’s note: In this 2nd edition, the following article has been added: Laverty H and Meulien P (2019) The Innovative Medicines Initiative −10 Years of Public-Private Collaboration. Front. Med. 6:275. doi: 10.3389/fmed.2019.00275
Author: Geraldine A. Van der Auwera
Publisher: "O'Reilly Media, Inc."
ISBN: 1491975148
Category : Science
Languages : en
Pages : 538
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Book Description
Data in the genomics field is booming. In just a few years, organizations such as the National Institutes of Health (NIH) will host 50+ petabytesâ??or over 50 million gigabytesâ??of genomic data, and theyâ??re turning to cloud infrastructure to make that data available to the research community. How do you adapt analysis tools and protocols to access and analyze that volume of data in the cloud? With this practical book, researchers will learn how to work with genomics algorithms using open source tools including the Genome Analysis Toolkit (GATK), Docker, WDL, and Terra. Geraldine Van der Auwera, longtime custodian of the GATK user community, and Brian Oâ??Connor of the UC Santa Cruz Genomics Institute, guide you through the process. Youâ??ll learn by working with real data and genomics algorithms from the field. This book covers: Essential genomics and computing technology background Basic cloud computing operations Getting started with GATK, plus three major GATK Best Practices pipelines Automating analysis with scripted workflows using WDL and Cromwell Scaling up workflow execution in the cloud, including parallelization and cost optimization Interactive analysis in the cloud using Jupyter notebooks Secure collaboration and computational reproducibility using Terra
Author: Abhirup Khanna
Publisher: John Wiley & Sons
ISBN: 1394234171
Category : Computers
Languages : en
Pages : 737
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Book Description
The book is a comprehensive guide that explores the use of artificial intelligence and machine learning in drug discovery and development covering a range of topics, including the use of molecular modeling, docking, identifying targets, selecting compounds, and optimizing drugs. The intersection of Artificial Intelligence (AI) and Machine Learning (ML) within the field of drug design and development represents a pivotal moment in the history of healthcare and pharmaceuticals. The remarkable synergy between cutting-edge technology and the life sciences has ushered in a new era of possibilities, offering unprecedented opportunities, formidable challenges, and a tantalizing glimpse into the future of medicine. AI can be applied to all the key areas of the pharmaceutical industry, such as drug discovery and development, drug repurposing, and improving productivity within a short period. Contemporary methods have shown promising results in facilitating the discovery of drugs to target different diseases. Moreover, AI helps in predicting the efficacy and safety of molecules and gives researchers a much broader chemical pallet for the selection of the best molecules for drug testing and delivery. In this context, drug repurposing is another important topic where AI can have a substantial impact. With the vast amount of clinical and pharmaceutical data available to date, AI algorithms find suitable drugs that can be repurposed for alternative use in medicine. This book is a comprehensive exploration of this dynamic and rapidly evolving field. In an era where precision and efficiency are paramount in drug discovery, AI and ML have emerged as transformative tools, reshaping the way we identify, design, and develop pharmaceuticals. This book is a testament to the profound impact these technologies have had and will continue to have on the pharmaceutical industry, healthcare, and ultimately, patient well-being. The editors of this volume have assembled a distinguished group of experts, researchers, and thought leaders from both the AI, ML, and pharmaceutical domains. Their collective knowledge and insights illuminate the multifaceted landscape of AI and ML in drug design and development, offering a roadmap for navigating its complexities and harnessing its potential. In each section, readers will find a rich tapestry of knowledge, case studies, and expert opinions, providing a 360-degree view of AI and ML’s role in drug design and development. Whether you are a researcher, scientist, industry professional, policymaker, or simply curious about the future of medicine, this book offers 19 state-of-the-art chapters providing valuable insights and a compass to navigate the exciting journey ahead. Audience The book is a valuable resource for a wide range of professionals in the pharmaceutical and allied industries including researchers, scientists, engineers, and laboratory workers in the field of drug discovery and development, who want to learn about the latest techniques in machine learning and AI, as well as information technology professionals who are interested in the application of machine learning and artificial intelligence in drug development.
Author: Cybellium
Publisher: YouGuide Ltd
ISBN: 1836798903
Category : Computers
Languages : en
Pages : 257
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Book Description
Welcome to the forefront of knowledge with Cybellium, your trusted partner in mastering the cutting-edge fields of IT, Artificial Intelligence, Cyber Security, Business, Economics and Science. Designed for professionals, students, and enthusiasts alike, our comprehensive books empower you to stay ahead in a rapidly evolving digital world. * Expert Insights: Our books provide deep, actionable insights that bridge the gap between theory and practical application. * Up-to-Date Content: Stay current with the latest advancements, trends, and best practices in IT, Al, Cybersecurity, Business, Economics and Science. Each guide is regularly updated to reflect the newest developments and challenges. * Comprehensive Coverage: Whether you're a beginner or an advanced learner, Cybellium books cover a wide range of topics, from foundational principles to specialized knowledge, tailored to your level of expertise. Become part of a global network of learners and professionals who trust Cybellium to guide their educational journey. www.cybellium.com
Author: Jaydip Sen
Publisher: BoD – Books on Demand
ISBN: 9535132431
Category : Computers
Languages : en
Pages : 142
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Book Description
In the era of Internet of Things and with the explosive worldwide growth of electronic data volume, and associated need of processing, analysis, and storage of such humongous volume of data, it has now become mandatory to exploit the power of massively parallel architecture for fast computation. Cloud computing provides a cheap source of such computing framework for large volume of data for real-time applications. It is, therefore, not surprising to see that cloud computing has become a buzzword in the computing fraternity over the last decade. This book presents some critical applications in cloud frameworks along with some innovation design of algorithms and architecture for deployment in cloud environment. It is a valuable source of knowledge for researchers, engineers, practitioners, and graduate and doctoral students working in the field of cloud computing. It will also be useful for faculty members of graduate schools and universities.
Author: Zhong Wang
Publisher: World Scientific
ISBN: 9811242488
Category : Science
Languages : en
Pages : 210
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Book Description
Breakthroughs in high-throughput genome sequencing and high-performance computing technologies have empowered scientists to decode many genomes including our own. Now they have a bigger ambition: to fully understand the vast diversity of microbial communities within us and around us, and to exploit their potential for the improvement of our health and environment. In this new field called metagenomics, microbial genomes are sequenced directly from the habitats without lab cultivation. Computational metagenomics, however, faces both a data challenge that deals with tens of tera-bases of sequences and an algorithmic one that deals with the complexity of thousands of species and their interactions.This interdisciplinary book is essential reading for those who are interested in beginning their own journey in computational metagenomics. It is a prism to look through various intricate computational metagenomics problems and unravel their three distinctive aspects: metagenomics, data engineering, and algorithms. Graduate students and advanced undergraduates from genomics science or computer science fields will find that the concepts explained in this book can serve as stepping stones for more advanced topics, while metagenomics practitioners and researchers from similar disciplines may use it to broaden their knowledge or identify new research targets.
