Genetic Manipulation of Molecular Chaperone-encoding Genes in Streptomyces PDF Download
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Author: Anna-Marie E. Brassington
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Author: Anna-Marie E. Brassington
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Author:
Publisher:
ISBN:
Category : Dissertations, Academic
Languages : en
Pages : 774
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Theses on any subject submitted by the academic libraries in the UK and Ireland.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309219396
Category : Science
Languages : en
Pages : 570
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Book Description
Many potential applications of synthetic and systems biology are relevant to the challenges associated with the detection, surveillance, and responses to emerging and re-emerging infectious diseases. On March 14 and 15, 2011, the Institute of Medicine's (IOM's) Forum on Microbial Threats convened a public workshop in Washington, DC, to explore the current state of the science of synthetic biology, including its dependency on systems biology; discussed the different approaches that scientists are taking to engineer, or reengineer, biological systems; and discussed how the tools and approaches of synthetic and systems biology were being applied to mitigate the risks associated with emerging infectious diseases. The Science and Applications of Synthetic and Systems Biology is organized into sections as a topic-by-topic distillation of the presentations and discussions that took place at the workshop. Its purpose is to present information from relevant experience, to delineate a range of pivotal issues and their respective challenges, and to offer differing perspectives on the topic as discussed and described by the workshop participants. This report also includes a collection of individually authored papers and commentary.
Author: E. Purshotaman
Publisher: DEStech Publications, Inc
ISBN: 1605951447
Category : Technology & Engineering
Languages : en
Pages : 741
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Book Description
This proceeding is indeed the result of remarkable cooperation of many distinguished experts, who came together to contribute their research work and comprehensive, in-depth and up to date review articles. We are thankful to all the contributing authors and co-authors for their valued contribution to this book. We would also like to express our gratitude to all the publishers and authors and others for granting us the copyright permissions to use their illustrations. 2013 International Conference on Biological, Medical and Chemical Engineering (BMCE2013) which will be held on December 1-2, 2013, Hong Kong, aims to provide a forum for accessing to the most up-to-date and authoritative knowledge from both Biological, Medical and Chemical Engineering. The dynamic Hong Kong, officially the Hong Kong Special Administrative Region of the People's Republic of China, is a largely self-governing territory of the People's Republic of China (PRC), facing the Guangdong Province in the north and the South China Sea to the east, west and south. Under the "one country, two systems" policy, Hong Kong enjoys considerable autonomy in all areas with the exception of foreign affairs and defense (which are the responsibility of the PRC Government). As part of this arrangement, Hong Kong continues to maintain its own currency, separate legal, political systems and other aspects that concern its way of life, many of which are distinct from those of mainland China. In relation with the title of this proceeding, Biological and Medical Engineering, Developmental biology, Environmental Biology, Evolutionary Biology, Marine Biology, Chemistry and Chemical Engineering Fundamentals, Chemical engineering educational challenges and development, Chemical reaction engineering, Chemical engineering equipment design and process design, Thermodynamics, Catalysis & reaction engineering, Advances in computational & numerical methods, Systems biology, Integration of Life Sciences & Engineering, Multi-scale and Multi-disciplinary Approaches, Controlled release of the active ingredient, Energy & nuclear sciences, Energy and environment, CFD & chemical engineering, Food engineering etc, has been targeted and included in this proceeding. The proceeding is the results of the contribution of a number of experts from the international scientific community in the respective field of research.
Author: Ipek Kurtboke
Publisher: Academic Press
ISBN: 012805140X
Category : Medical
Languages : en
Pages : 356
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Book Description
Microbial Resources: From Functional Existence in Nature to Applications provides an exciting interdisciplinary journey through the rapidly developing field of microbial resources, including relationships to aspects of microbiology. Covers the functional existence of microorganisms in nature, as well as the transfer of this knowledge for industrial and other applications. Examines the economic perspective of revealing the potential value of microbial material and figuring it into socio-economic value; legal perspectives; and how to organize a fair allotment of socio-economic benefits to all stakeholders who have effectively contributed to the preservation, study, and exploitation of microbiological material. - Covers aspects of foundational information related to microbiology, microbial ecology, and diversity, as well as new advances in microbial genomics - Provides information on the utilization of microbial resources in biotechnology - Covers legislative issues and related law in biodiscovery - Fills a need for a very broad audience and is a good resource for microbiologists seeking to know the extent of microbiology approaches, the policies associated with microbiology, and potential career paths for researchers - Has significant added value due to the inclusion of comprehensive coverage of the biology, ecology, biochemistry and international legislation surrounding these applications
Author: Kenneth Maiese
Publisher: Academic Press
ISBN: 012802755X
Category : Science
Languages : en
Pages : 474
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Book Description
Molecules to Medicine with mTOR: Translating Critical Pathways into Novel Therapeutic Strategies is a one-stop reference that thoroughly covers the mechanistic target of rapamycin (mTOR). mTOR, also known as the mammalian target of rapamycin, is a 289-kDa serine/threonine protein kinase that is ubiquitous throughout the body and has a critical role in gene transcription and protein formation, stem cell development, cell survival and senescence, aging, immunity, tissue regeneration and repair, metabolism, tumorigenesis, oxidative stress, and pathways of programmed cell death that include apoptosis and autophagy. Incorporating a translational medicine approach, this important reference highlights the basic cellular biology of mTOR pathways, presents the role of mTOR during normal physiologic function and disease, and illustrates how the mechanisms of mTOR can be targeted for current and future therapeutic treatment strategies. Coverage of mTOR signaling includes the entire life cycle of cells that impacts multiple systems of the body including those of nervous, cardiovascular, immune, musculoskeletal, endocrine, reproductive, renal, and respiratory origin. - Covers the role of mTOR by internationally recognized expert contributors in the field. - Provides a clear picture of the complexity of mTOR signaling as well as of the different approaches that could target this pathway at various levels. - Includes analysis of the role of mTOR and in both health and disease. - Serves as an important resource for a broad audience of healthcare providers, scientists, drug developers, and students in both clinical and research settings.
Author: Stuart K. Calderwood
Publisher: Springer Science & Business Media
ISBN: 1402064012
Category : Medical
Languages : en
Pages : 399
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Book Description
Heat shock proteins are emerging as important molecules in the development of cancer and as key targets in cancer therapy. These proteins enhance the growth of cancer cells and protect tumors from treatments such as drugs or surgery. However, new drugs have recently been developed particularly those targeting heat shock protein 90. As heat shock protein 90 functions to stabilize many of the oncogenes and growth promoting proteins in cancer cells, such drugs have broad specificity in many types of cancer cell and offer the possibility of evading the development of resistance through point mutation or use of compensatory pathways. Heat shock proteins have a further property that makes them tempting targets in cancer immunotherapy. These proteins have the ability to induce an inflammatory response when released in tumors and to carry tumor antigens to antigen presenting cells. They have thus become important components of anticancer vaccines. Overall, heat shock proteins are important new targets in molecular cancer therapy and can be approached in a number of contrasting approaches to therapy.
Author:
Publisher:
ISBN:
Category : Bioengineering
Languages : en
Pages : 830
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Author: Bernard R. Glick
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 724
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Book Description
The second edition explains the principles of recombinant DNA technology as well as other important techniques such as DNA sequencing, the polymerase chain reaction, and the production of monclonal antibodies.
Author: Sang Yup Lee
Publisher: John Wiley & Sons
ISBN: 352782345X
Category : Science
Languages : en
Pages : 1075
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Book Description
Learn more about foundational and advanced topics in metabolic engineering in this comprehensive resource edited by leaders in the field Metabolic Engineering: Concepts and Applications delivers a one-stop resource for readers seeking a complete description of the concepts, models, and applications of metabolic engineering. This guide offers practical insights into the metabolic engineering of major cell lines, including E. Coli, Bacillus and Yarrowia Lipolytica, and organisms, including human, animal, and plant). The distinguished editors also offer readers resources on microbiome engineering and the use of metabolic engineering in bioremediation. Written in two parts, Metabolic Engineering begins with the essential models and strategies of the field, like Flux Balance Analysis, Quantitative Flux Analysis, and Proteome Constrained Models. It also provides an overview of topics like Pathway Design, Metabolomics, and Genome Editing of Bacteria and Eukarya. The second part contains insightful descriptions of the practical applications of metabolic engineering, including specific examples that shed light on the topics within. In addition to subjects like the metabolic engineering of animals, humans, and plants, you’ll learn more about: Metabolic engineering concepts and a historical perspective on their development The different modes of analysis, including flux balance analysis and quantitative flux analysis An illuminating and complete discussion of the thermodynamics of metabolic pathways The Genome architecture of E. coli, as well as genome editing of both bacteria and eukarya An in-depth treatment of the application of metabolic engineering techniques to organisms including corynebacterial, bacillus, and pseudomonas, and more Perfect for students of biotechnology, bioengineers, and biotechnologists, Metabolic Engineering: Concepts and Applications also has a place on the bookshelves of research institutes, biotechnological institutes and industry labs, and university libraries. It's comprehensive treatment of all relevant metabolic engineering concepts, models, and applications will be of use to practicing biotechnologists and bioengineers who wish to solidify their understanding of the field.
