Author: James Robert EricksonPublisher:
ISBN:
Category :
Languages : en
Pages : 292
Book Description
Genetic and Molecular Characterization of Genes Involved in Glucose Repression of the GAL Genes in the Yeast Saccharomyces Cerevisiae
Author: James Robert EricksonPublisher:
ISBN:
Category :
Languages : en
Pages : 292
Book Description
A Molecular and Genetic Analysis of Glucose Repression of the GAL1 Gene of Saccharomyces Cerevisiae
Author: Jeffrey Scott FlickPublisher:
ISBN:
Category : Genetic regulation
Languages : en
Pages : 330
Book Description
The Isolation and Characterization of NGG1, a Novel Saccharomyces Cerevisiae Gene Required for Glucose Repression of the GAL Genes
Author: Angela Marie FurlanettoPublisher:
ISBN:
Category :
Languages : en
Pages : 248
Book Description
Genetic and Molecular Dissection of the Integration of Galactose and Glucose Signaling in Saccharomyces Cerevisiae Strains
Author: Renan Antonio Escalante ChongPublisher:
ISBN:
Category :
Languages : en
Pages :
Book Description
Cells need to sense the environment in order to survive, in particular they need to detect nutrients which will provide different building blocks and energy for the cell. This task is complicated by the fact that there can be multiple sources for the same type of nutrient available for the cell. A classical example of how cells sense multiple signals is given by carbon catabolite repression in the budding yeast S. cerevisiae. In this model the preferred carbon source glucose represses the genes used to metabolize an alternative source such as galactose. This means that the preferred carbohydrate glucose is thought to inhibit the induction of galactose genes when above a threshold concentration. Instead, we show that galactose metabolic genes (GAL) induction depends on the ratio of galactose and glucose. Surprisingly, we find that a critical portion of information processing occurs upstream of the canonical components of the GAL pathway. We then explore how cells choose between different responses to the environment. Specifically, we set out to characterize the variability in the response to combinations of galactose and glucose between several natural yeast isolates. To elucidate the genetic basis of this phenotypic variation we use QTL mapping on these strains. Our study reveals that a signal transducer GAL3 plays a central role in establishing variation in GAL gene induction.Lastly, we focus on the control of transcription in the cell. Many promoters in the cell produce both a coding transcript and a divergent transcript. To identify mutants that affect transcriptional directionality we use a bidirectionalfluorescent protein reporter in the yeast nonessential gene deletion collection. We determine that chromatin assembly can regulate divergent transcription. Moreover, mutations in the chromatin assembly factor CAF-I can lead to genome wide derepression of nascent divergent transcription.
Insights Into the Molecular Genetics of Hexose Transporter Gene Regulation in Saccharomyces Cerevisiae
Author: Kevin L. DietzelPublisher:
ISBN:
Category :
Languages : en
Pages : 336
Book Description
Molecular Characterization of Genes Involved in DNA Repair in Saccharomyces Cerevisiae
Author: Joyce Geneine SlusserPublisher:
ISBN:
Category :
Languages : en
Pages : 168
Book Description
Yeast Sugar Metabolism
Author: Friedrich K. ZimmermannPublisher: CRC Press
ISBN: 9781566764667
Category : Technology & Engineering
Languages : en
Pages : 590
Book Description
Yeast Sugar Metabolism looks at the biomechanics, genetics, biotechnology and applications of yeast sugar. The yeast Saccharomyces cereisiae has played a central role in the evolution of microbiology biochemistry and genetics, in addition to its use of a technical microbe for the production of alcoholic beverages and leavening of dough.
Genetics and Biotechnology
Author: Ulrich KückPublisher: Springer Science & Business Media
ISBN: 3662103648
Category : Science
Languages : en
Pages : 372
Book Description
Mycology, the study of fungi, originated as a subdiscipline of botany and was a descriptive discipline, largely neglected as an experimental science until the early years of this century. A seminal paper by Blakeslee in 1904 provided evidence for self incompatibility, termed "heterothallism", and stimulated interest in studies related to the control of sexual reproduction in fungi by mating-type specificities. Soon to follow was the demonstration that sexually reproducing fungi exhibit Mendelian inheritance and that it was possible to conduct formal genetic analysis with fungi. The names Burgeff, Kniep and Lindegren are all associated with this early period of fungal genetics research. These studies and the discovery of penicillin by Fleming, who shared a Nobel Prize in 1945, provided further impetus for experimental research with fungi. Thus began a period of interest in mutation induction and analysis of mutants for bio chemical traits. Such fundamental research, conducted largely with Neurospora crassa, led to the one gene: one enzyme hypothesis and to a second Nobel Prize for fungal research awarded to Beadle and Tatum in 1958. Fundamental research in biochemical genetics was extended to other fungi, especially to Saccharomyces cere visiae, and by the mid-1960s fungal systems were much favored for studies in eukaryotic molecular biology and were soon able to compete with bacterial systems in the molecular arena.
A Genetic and Molecular Characterization of the REC104 Gene and Its Involvement in Meiotic Recombination in the Yeast Saccharomyces Cerevisiae
Author: Anne M. GalbraithPublisher:
ISBN:
Category : Genetic recombination
Languages : en
Pages : 810
Book Description
Dissecting the Glucose Sensing and Signaling Pathway in Saccharomyces Cerevisiae
Author: Vidhya RamakrishnanPublisher:
ISBN:
Category :
Languages : en
Pages : 466
Book Description
