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Author: Samuel H. Barondes
Publisher: Oxford University Press, USA
ISBN: 0195131061
Category : Medical
Languages : en
Pages : 250
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Book Description
In Mood Genes, leading psychiatrist and biological researcher Samuel B arondes answers these questions in a way that renders a complex subjec t both exciting and understandable. Focusing on manic depressive illne ss, which affects about one percent of the population and has long bee n known to run in families, Barondes describes the fascinating hunt fo r genes--called mood genes--that influence the inherited vulnerability to severe mood disorders. He builds the compelling story of this hunt on the histories of two families riddled with manic-depression, expla ining what it means to have an inherited predisposition to a severe mo od disorder, how to find the mood genes that are responsible, and what will happen as mood genes are found.
Author: Leon E. Rosenberg
Publisher: Bookbaby
ISBN: 9781098318109
Category :
Languages : en
Pages : 426
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Book Description
One can have a successful professional career, and a meaningful, personal life while struggling all the while with a common mental illness: bipolar disorder. This memoir describes the author's widely recognized research in the field of inherited metabolic disorders in children, his pivotal role as Dean of the Yale University School of Medicine and as Chief Scientific Officer of the Bristol-Myers Squibb Company, his contributions to public affairs, and his efforts as a teacher of medical, graduate, undergraduate, and high school students. These stories are interwoven with that of his personal encounter with bipolar disorder--one that has gone on for 60 years, and once nearly ended his life in a Prozac-precipitated suicide attempt. This is a narrative of hope and resilience, not one of desolation and despair.
Author: Samuel H. Barondes
Publisher: Oxford University Press, USA
ISBN: 0195131061
Category : Medical
Languages : en
Pages : 250
Get Book Here
Book Description
In Mood Genes, leading psychiatrist and biological researcher Samuel B arondes answers these questions in a way that renders a complex subjec t both exciting and understandable. Focusing on manic depressive illne ss, which affects about one percent of the population and has long bee n known to run in families, Barondes describes the fascinating hunt fo r genes--called mood genes--that influence the inherited vulnerability to severe mood disorders. He builds the compelling story of this hunt on the histories of two families riddled with manic-depression, expla ining what it means to have an inherited predisposition to a severe mo od disorder, how to find the mood genes that are responsible, and what will happen as mood genes are found.
Author: Michael S. Ritsner
Publisher: Springer Science & Business Media
ISBN: 9048122988
Category : Medical
Languages : en
Pages : 233
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Book Description
Neuropsychiatric disorders such as schizophrenia, mood disorders, Alzheimer’s disease, epilepsy, alcoholism, substance abuse and others are one of the most debilitating illnesses worldwide characterizing by the complexity of the causes, and lacking the laboratory tests that may promote diagnostic and prognostic procedures. Recent advances in neuroscience, genomic, genetic, proteomic and metabolomic knowledge and technologies have opened the way to searching biomarkers and endophenotypes, which may offer powerful and exciting opportunity to understand the etiology and the underlying pathophysiological mechanisms of neuropsychiatric disorders. The challenge now is to translate these advances into meaningful diagnostic and therapeutic advances. This book offers a broad synthesis of the current knowledge about diverse topics of the biomarker and endophenotype strategies in neuropsychiatry. The book is organized into four interconnected volumes: “Neuropsychological Endophenotypes and Biomarkers” (with overview of methodological issues of the biomarker and endophenotype approaches in neuropsychiatry and some technological advances), “Neuroanatomical and Neuroimaging Endophenotypes and Biomarkers”, “Metabolic and Peripheral Biomarkers” and “Molecular Genetic and Genomic Markers”. The contributors are internationally and nationally recognized researchers and experts from 16 countries. This four-volume handbook is intended for a broad spectrum of readers including neuroscientists, psychiatrists, neurologists, endocrinologists, pharmacologists, clinical psychologists, general practitioners, geriatricians, health care providers in the field of neurology and mental health interested in trends that have crystallized in the last decade, and trends that can be expected to further evolve in the coming years. It is hoped that this book will also be a useful resource for the teaching of psychiatry, neurology, psychology and mental health.
Author: John I. Nurnberger
Publisher: Cambridge University Press
ISBN: 0521896495
Category : Medical
Languages : en
Pages : 415
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Book Description
A comprehensive, up-to-date resource providing information about genetic influences on disorders of behavior.
Author: Bernhard Baune
Publisher: Academic Press
ISBN: 0128131772
Category : Medical
Languages : en
Pages : 594
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Book Description
Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. - Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics - Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry - Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective
Author: Stephen Strakowski
Publisher: Oxford University Press
ISBN: 0197574521
Category : Manic-depressive illness
Languages : en
Pages : 329
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Book Description
"Although efforts to examine the structure and function of the human brain stretch back centuries (Paluzzi et al, 2007), techniques allowing the study of living humans are a relatively recent development. Early investigators confined themselves to largely studying external features, with 18th century methodologies such as phrenology purporting to link extracranial proxies for brain size and structure to specific personality traits (Livianos-Aldana et al, 2007). However, these techniques did not prove useful for either clinical or research purposes. Two-dimensional x-ray imaging, while constituting an important medical advance, did not provide sufficient soft tissue contrast to be useful for studying "functional" psychiatric disorders such as bipolar disorder; techniques to enhance contrast, such as ventriculography and pneumoencephalography were similarly limited (Figure 1.1). Wide-spread in vivo studies of brain morphometry had to await the development of computed tomography imaging (CT) in the early 1970s. By the early 1980s CT was already being applied to the study of bipolar disorder (Pearlson et al, 1981)"--
Author: Randolph M. Nesse, MD
Publisher: Penguin
ISBN: 1101985682
Category : Medical
Languages : en
Pages : 386
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Book Description
A founder of the field of evolutionary medicine uses his decades of experience as a psychiatrist to provide a much-needed new framework for making sense of mental illness. Why do I feel bad? There is real power in understanding our bad feelings. With his classic Why We Get Sick, Dr. Randolph Nesse helped to establish the field of evolutionary medicine. Now he returns with a book that transforms our understanding of mental disorders by exploring a fundamentally new question. Instead of asking why certain people suffer from mental illness, Nesse asks why natural selection has left us all with fragile minds. Drawing on revealing stories from his own clinical practice and insights from evolutionary biology, Nesse shows how negative emotions are useful in certain situations, yet can become overwhelming. Anxiety protects us from harm in the face of danger, but false alarms are inevitable. Low moods prevent us from wasting effort in pursuit of unreachable goals, but they often escalate into pathological depression. Other mental disorders, such as addiction and anorexia, result from the mismatch between modern environment and our ancient human past. And there are good evolutionary reasons for sexual disorders and for why genes for schizophrenia persist. Taken together, these and many more insights help to explain the pervasiveness of human suffering, and show us new paths for relieving it by understanding individuals as individuals.
Author: Paul Meier
Publisher: Tyndale House Publishers, Inc.
ISBN: 1414375786
Category : Religion
Languages : en
Pages : 187
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Book Description
Many common psychological problems, such as depression, bipolar disorder, obsessive-compulsive disorder, and ADHD, can be linked to chemical imbalances in the brain. Dr. Paul Meier, whose clinic treats thousands of people per week, has written Blue Genes to help find answers for those who struggle. Through fascinating case studies, Dr. Meier shows the dramatic difference counseling and medicine can make. This empowering book addresses how genetics, environment, diet, fitness, and spirituality all affect our minds and our quality of life.
Author: Yogesh Dwivedi
Publisher: CRC Press
ISBN: 143983881X
Category : Medical
Languages : en
Pages : 485
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Book Description
With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.
Author: Stephen V. Faraone
Publisher: Guilford Publication
ISBN: 9781572307391
Category : Psychology
Languages : en
Pages : 272
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Book Description
This volume offers a comprehensive and readable introduction to the science and practice of psychiatric genetics. The authors illuminate the complex interplay of genes and environmental factors involved in the causation and expression of frequently encountered disorders including schizophrenia, bipolar disorder, depression, and Alzheimer disease. Outlining important recent findings, the book describes not only what scientists have learned, but also how these discoveries have been made. Clinicians, students, and researchers will gain the basic knowledge they need to evaluate reports of genetic research, understand implications for treatment, and communicate genetic information to clients and families.
