Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine

Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine PDF Author: Johnny Huard
Publisher: Springer Science & Business Media
ISBN: 9780817640712
Category : Medical
Languages : en
Pages : 312

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Book Description
This book has been written in response to the many physicians and scien tists working on the development of biological approaches to providing therapies for many orthopaedic disorders as well as to improving the healing of many tissues of the musculoskeletal system. The first goal of this book is to make the language compatible between the bench scientist and the clinician working in orthopaedic and sports medicine in order to cover specific areas of the orthopaedic discipline where the treatment can be improved and/or changed by the advancements in molecular medicine. Advancements in molecular biology, which encompass the study of the genetic basis of disease, have produced new diagnostic methods and drug therapies for genetic diseases and acquired disorders. The growth in the understanding of human genetics has also led to the initiation of many human gene therapy experiments. Although many approved therapeutic clinical trials using this new technology have been performed in the last ten years, the first clinical trial using this technology in the area of orthopaedics was performed at the University of Pittsburgh.

Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine

Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine PDF Author: Johnny Huard
Publisher: Springer Science & Business Media
ISBN: 9780817640712
Category : Medical
Languages : en
Pages : 312

Get Book Here

Book Description
This book has been written in response to the many physicians and scien tists working on the development of biological approaches to providing therapies for many orthopaedic disorders as well as to improving the healing of many tissues of the musculoskeletal system. The first goal of this book is to make the language compatible between the bench scientist and the clinician working in orthopaedic and sports medicine in order to cover specific areas of the orthopaedic discipline where the treatment can be improved and/or changed by the advancements in molecular medicine. Advancements in molecular biology, which encompass the study of the genetic basis of disease, have produced new diagnostic methods and drug therapies for genetic diseases and acquired disorders. The growth in the understanding of human genetics has also led to the initiation of many human gene therapy experiments. Although many approved therapeutic clinical trials using this new technology have been performed in the last ten years, the first clinical trial using this technology in the area of orthopaedics was performed at the University of Pittsburgh.

Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine

Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine PDF Author: Johnny Huard
Publisher: Springer Science & Business Media
ISBN: 1461221269
Category : Medical
Languages : en
Pages : 294

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Book Description
This book has been written in response to the many physicians and scien tists working on the development of biological approaches to providing therapies for many orthopaedic disorders as well as to improving the healing of many tissues of the musculoskeletal system. The first goal of this book is to make the language compatible between the bench scientist and the clinician working in orthopaedic and sports medicine in order to cover specific areas of the orthopaedic discipline where the treatment can be improved and/or changed by the advancements in molecular medicine. Advancements in molecular biology, which encompass the study of the genetic basis of disease, have produced new diagnostic methods and drug therapies for genetic diseases and acquired disorders. The growth in the understanding of human genetics has also led to the initiation of many human gene therapy experiments. Although many approved therapeutic clinical trials using this new technology have been performed in the last ten years, the first clinical trial using this technology in the area of orthopaedics was performed at the University of Pittsburgh.

Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine

Gene Therapy and Tissue Engineering in Orthopaedic and Sports Medicine PDF Author: Johnny Huard
Publisher:
ISBN: 9783764340711
Category : Gene therapy
Languages : en
Pages : 286

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Book Description
This book has been written in response to the many physicians and scien- tists working on the development of biological approaches to providing therapies for many orthopaedic disorders as well as to improving the healing of many tissues of the musculoskeletal system. The first goal of this book is to make the language compatible between the bench scientist and the clinician working in orthopaedic and sports medicine in order to cover specific areas of the orthopaedic discipline where the treatment can be improved and/or changed by the advancements in molecular medicine. Advancements in molecular biology, which encompass the study of the genetic basis of disease, have produced new diagnostic methods and drug therapies for genetic diseases and acquired disorders. The growth in the understanding of human genetics has also led to the initiation of many human gene therapy experiments. Although many approved therapeutic clinical trials using this new technology have been performed in the last ten years, the first clinical trial using this technology in the area of orthopaedics was performed at the University of Pittsburgh.

Orthobiologics

Orthobiologics PDF Author: Giuseppe Filardo
Publisher: Springer Nature
ISBN: 3030847446
Category : Medical
Languages : en
Pages : 394

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Book Description
This book presents the evidence related to the use of injectable biologics to provide faster and better healing for musculoskeletal lesions and conditions. The authors discuss approaches, such as blood derivatives and cell concentrates, applied to lesions of muscles, ligaments, tendons, bones, meniscus and cartilage, as well as osteoarthritis. Chapters are written by some of the most influential opinion leaders in the field, with up-to-date review of the current literature, where the authors explore both the potential and the limitations of these minimally invasive and promising treatments. The first section is devoted to the formulations and rationale for the use of injectable orthobiologics, while the second section reviews current treatment methods applied to specific joints and pathologies – ranging from tendinopathies through non-unions to articular degenerative processes – as well as the results of these treatment approaches. The third section explores future perspectives, such as pluripotent stem cells, gene therapy, and the stimulation of intrinsic stromal cell niches. Appealing to a broad readership, this book will be of interest to both laboratory research scientists and clinicians, including orthopedists, sports physicians, physiatrists, and regenerative medicine experts.

Scaffolding In Tissue Engineering

Scaffolding In Tissue Engineering PDF Author: Peter X. Ma
Publisher: CRC Press
ISBN: 1420027565
Category : Medical
Languages : en
Pages : 656

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Book Description
The growing interest in scaffolding design and increasing research programs dedicated to regenerative medicine corroborate the need for Scaffolding in Tissue Engineering. While certain books and journal articles address various aspects in the field, this is the first current, comprehensive text focusing on scaffolding for tissue engineering.

Biomaterials Science

Biomaterials Science PDF Author: Buddy D. Ratner
Publisher: Academic Press
ISBN: 0125824637
Category : Medical
Languages : en
Pages : 880

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Book Description
This second edition of Biomaterials Science leads the field by providing a balanced, insightful view of biomaterials. Contributions from pre-eminent researchers and practitioners from diverse academic and professional backgrounds have been integrated into a cohesive curriculum which includes pertinent principles of cell biology, immunology and pathology focusing on the clinical uses of biomaterials as components of implants, devices, and artificial organs, and their uses in biotechnology. The materials science and engineering of synthetic and natural biomaterials and the characterization of their physical, chemical, biochemical and surface properties, and mechanisms and evaluation of interactions with tissue, are also addressed in detail. Book jacket.

Stem Cells in Endocrinology

Stem Cells in Endocrinology PDF Author: Linda B. Lester
Publisher: Springer Science & Business Media
ISBN: 1592599001
Category : Medical
Languages : en
Pages : 277

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Book Description
A critical review by prominent experts of both the cutting-edge of stem cell biology and the application of stem cells to endocrine diseases, including diabetes, infertility, and liver-associated metabolic disorders. The authors discuss current research to modify stem cells, develop an endocrine-like cell, and use adult bone marrow stem cells to treat autoimmune diseases, including endocrine-based autoimmune diseases. Topics of interest include a review of all stem cell subtypes and their characteristics, approaches to promoting endocrine development from stem cells, and evidence for endocrine cell function from stem cells. The authors also outline how best to develop preclinical studies that will determine the safety and efficacy of stem cell therapies for endocrine disorders.

Orthopedic Sports Medicine

Orthopedic Sports Medicine PDF Author: Fabrizio Margheritini
Publisher: Springer Science & Business Media
ISBN: 8847017025
Category : Medical
Languages : en
Pages : 524

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Book Description
Aim of this book is to give an update on the main issues in sports traumatology and orthopedics, involving different body sections. Exploring the most important aspects of sports medicine - from anatomy to normal movements description, from diagnosis to sports injuries treatment, from conservative to surgical treatments - it gives a global overview of the field, describing also diagnostic tools recently introduced in this field, such as hip arthroscopy, and taking into consideration related areas like nutrition, prevention, training and rehabilitation. The single chapters deal with relevant problems such as emergencies on the field, pathologies of the upper and lower extremity, spine problems in athletes. Each injury is approached on the basis of both the specific body area and of the different sports/activities. Written by a multidisciplinary team of experts, this volume will be a fundamental book for orthopedic surgeons, physiotherapists, general practitioners, personal and athletic trainers, offering them a useful tool for the management of most frequent injuries in sports medicine.

Rehabilitation for the Postsurgical Orthopedic Patient

Rehabilitation for the Postsurgical Orthopedic Patient PDF Author: Lisa Maxey
Publisher: Elsevier Health Sciences
ISBN: 0323077471
Category : Medical
Languages : en
Pages : 665

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Book Description
With detailed descriptions of orthopedic surgeries, Rehabilitation for the Postsurgical Orthopedic Patient, 3rd Edition provides current, evidence-based guidelines to designing effective rehabilitation strategies. Coverage of each condition includes an overview of the orthopedic patient's entire course of treatment from pre- to post-surgery. For each phase of rehabilitation, this book describes the postoperative timeline, the goals, potential complications and precautions, and appropriate therapeutic procedures. New to this edition are a full-color design and new chapters on disc replacement, cartilage replacement, hallux valgus, and transitioning the running athlete. Edited by Lisa Maxey and Jim Magnusson, and with chapters written by both surgeons and physical therapists, Rehabilitation for the Postsurgical Orthopedic Patient provides valuable insights into the use of physical therapy in the rehabilitation process. Comprehensive, evidence-based coverage provides an overview of the orthopedic patient's entire course of treatment from pre- to post-surgery, including a detailed look at the surgical procedures and therapy guidelines that can be used to design the appropriate rehabilitation programs. Case study vignettes with critical thinking questions help you develop critical reasoning skills. Indications and considerations for surgery describe the mechanics of the injury and the repair process so you can plan an effective rehabilitation program. Therapy guidelines cover each phase of rehabilitation with specifics as to the expected time span and goals for each phase. Evidence-based coverage includes the latest clinical research to support treatment decisions. Overview of soft tissue and bone healing considerations after surgery helps you understand the rationale behind the timelines for the various physical therapy guidelines. A Troubleshooting section in each chapter details potential pitfalls in the recovery from each procedure. Over 300 photos and line drawings depict concepts, procedures, and rehabilitation. Detailed tables break down therapy guidelines and treatment options for quick reference. Expert contributors include surgeons describing the indications and considerations for surgery as well as the surgery itself, and physical or occupational therapists discussing therapy guidelines. New coverage of current orthopedic surgeries and rehabilitation includes topics such as disc replacement, cartilage replacement, hallux valgus, and transitioning the running athlete. New full-color design and illustrations visually reinforce the content. Updated Suggested Home Maintenance boxes in every chapter provide guidance for patients returning home. References linked to MEDLINE abstracts make it easy to access evidence-based information for better clinical decision-making.

Football Traumatology

Football Traumatology PDF Author: Piero Volpi
Publisher: Springer Science & Business Media
ISBN: 8847004195
Category : Medical
Languages : en
Pages : 414

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Book Description
Football is probably the most widespread sport in the world. Like many other sports football has undergone major changes. It has increased in intensity, speed, and other factors contributing to increased risks of traumatic injury. Footballers, trainers, and the sport's medical staff are asking for greater information on the traumatic lesions associated with football. The primary role of those concerned with the health of footballers is to enforce preventive measures to reduce the risks of trauma.