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Author: Dineshkumar Pandian
Publisher: Dineshkumar Pandian
ISBN:
Category : Science
Languages : en
Pages : 52
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Book Description
"Gene Editing 101: Principles and Applications" is an essential guide for anyone interested in understanding the fundamentals of gene editing and its applications. This e-book provides a comprehensive overview of the principles and technologies used in gene editing, including the CRISPR-Cas9 system, TALENs, and zinc finger nucleases. It also covers the ethical considerations and potential risks associated with gene editing, as well as the current regulations governing its use. The e-book includes real-world examples of gene editing applications, such as genetic engineering of crops, gene therapy for genetic diseases, and editing of animal genomes for research purposes. It also explores the potential for gene editing to address global challenges, such as climate change, food insecurity, and disease outbreaks. With clear explanations and engaging illustrations, "Gene Editing 101" is the perfect resource for students, researchers, and anyone interested in the cutting-edge field of gene editing. Whether you're a beginner or an expert in the field, this e-book is an indispensable guide to the science, ethics, and applications of gene editing.
Author: Dineshkumar Pandian
Publisher: Dineshkumar Pandian
ISBN:
Category : Science
Languages : en
Pages : 52
Get Book
Book Description
"Gene Editing 101: Principles and Applications" is an essential guide for anyone interested in understanding the fundamentals of gene editing and its applications. This e-book provides a comprehensive overview of the principles and technologies used in gene editing, including the CRISPR-Cas9 system, TALENs, and zinc finger nucleases. It also covers the ethical considerations and potential risks associated with gene editing, as well as the current regulations governing its use. The e-book includes real-world examples of gene editing applications, such as genetic engineering of crops, gene therapy for genetic diseases, and editing of animal genomes for research purposes. It also explores the potential for gene editing to address global challenges, such as climate change, food insecurity, and disease outbreaks. With clear explanations and engaging illustrations, "Gene Editing 101" is the perfect resource for students, researchers, and anyone interested in the cutting-edge field of gene editing. Whether you're a beginner or an expert in the field, this e-book is an indispensable guide to the science, ethics, and applications of gene editing.
Author: Kiran Musunuru
Publisher: Academic Press
ISBN: 0128236477
Category : Science
Languages : en
Pages : 231
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Book Description
Genome Editing: A Practical Guide to Research and Clinical Applications is geared towards investigators interested in learning how to use CRISPR-Cas9-based technologies, with a focus on cardiovascular research and clinical applications. Covering a range of topics from the basics of genome editing to design considerations, to assessments and applications, this reference allows readers to get started and establish a full workflow from the beginning of the project to its full completion. With worked examples drawn from real-life experiments, as well as troubleshooting and pitfalls to avoid, the book serves as an essential reference for researchers and investigators in both cardiovascular and biomedical research. Help readers familiarise with the variety of genome-editing approaches that are being applied in cardiovascular research and medicine, i.e., both research applications and clinical applications Understand the use of genome editing through worked examples (based on real-life experiments) in which CRISPR-Cas9 is employed, online tools to design CRISPR-Cas9 reagents, methods to interpret data from genome-editing experiments, the downsides of genome-editing technology - both the scientific and ethical pitfalls to avoid Written in an easy-to-follow manner, guiding readers from the design of the project to its completion Includes unpublished and new methods
Author: Anshu Alok
Publisher: CRC Press
ISBN: 1040112137
Category : Science
Languages : en
Pages : 329
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Book Description
CRISPR/Cas has emerged, as a powerful genetic engineering tool. It is simple yet highly affordable and robust. This book provides a basic introduction to the mechanism and architecture of the CRISPR/Cas. It enlightens the readers about the new advancements such as gene insertion, transcriptional activation, suppression, gene tagging, multiplexing, base editing, prime editing, and tissue culture free editing which makes it easier for crop improvement. With such technologies, application of genome editing has opened new paths for crop improvements and sustainable agriculture. The current book will be useful for beginners to understand these tools and how to use them in a better and more efficient way.
Author: Raymond Ching-Bong Wong
Publisher: Frontiers Media SA
ISBN: 2889719952
Category : Science
Languages : en
Pages : 252
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Book Description
Author: Zhiying Zhang
Publisher: Frontiers Media SA
ISBN: 2889637794
Category :
Languages : en
Pages : 135
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Book Description
Author: Katherine Paris
Publisher: Springer Nature
ISBN: 3031218205
Category : Science
Languages : en
Pages : 281
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Book Description
This monograph introduces current genome editing technologies—clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated (Cas) systems, transcription activator-like effector nucleases (TALENs), and zinc-finger nucleases (ZFNs)—and provides an assessment of the risk of misuse of these technologies based on the following parameters: accessibility, ease of misuse, magnitude of potential harm, and imminence of potential misuse. The findings from this assessment are applied to analyze and evaluate the threat posed by the intentional misuse of genome editing technologies to develop biological weapons. Furthermore, the book discusses the implications of misuse for different applications of genome editing, such as making existing pathogens more dangerous, modifying the human microbiome, weaponizing gene drives, engineering super soldiers, and augmenting the general population to confer economic advantages. Technologies that enable genome editing with programmable nucleases—including CRISPR, TALEN, and ZFN—allow for the precise genetic modification of organisms and cultured cells. While these technologies are used for a variety of beneficial applications, intelligence and defense experts have raised concerns that genome editing technologies, especially CRISPR, could be misused to develop new and improved biological weapons. Furthermore, experts worry that the number and type of actors who could potentially misuse genome editing is dramatically increasing given the democratization of biology, which is allowing biology to become more accessible to everyone including nonexperts. The book provides a comprehensive assessment of how feasible it is for users with different levels of knowledge and skill to acquire and then to apply the technologies to develop a biological weapon. It also provides an assessment of governability and a tailored set of recommendations that address security concerns. These recommendations are sensitive to the cost-benefit trade-off of regulating genome editing technologies. The book targets researchers as well as intelligence analysts, defense and security personnel, and policymakers.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309452880
Category : Medical
Languages : en
Pages : 329
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Book Description
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
Author: The Royal Society
Publisher: National Academies Press
ISBN: 0309671132
Category : Medical
Languages : en
Pages : 239
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Book Description
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
Author: Kevin Davies
Publisher: Simon and Schuster
ISBN: 1643133942
Category : Science
Languages : en
Pages : 402
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Book Description
One of the world's leading experts on genetics unravels one of the most important breakthroughs in modern science and medicine. IIf our genes are, to a great extent, our destiny, then what would happen if mankind could engineer and alter the very essence of our DNA coding? Millions might be spared the devastating effects of hereditary disease or the challenges of disability, whether it was the pain of sickle-cell anemia to the ravages of Huntington’s disease. But this power to “play God” also raises major ethical questions and poses threats for potential misuse. For decades, these questions have lived exclusively in the realm of science fiction, but as Kevin Davies powerfully reveals in his new book, this is all about to change. Engrossing and page-turning, Editing Humanity takes readers inside the fascinating world of a new gene editing technology called CRISPR, a high-powered genetic toolkit that enables scientists to not only engineer but to edit the DNA of any organism down to the individual building blocks of the genetic code. Davies introduces readers to arguably the most profound scientific breakthrough of our time. He tracks the scientists on the front lines of its research to the patients whose powerful stories bring the narrative movingly to human scale. Though the birth of the “CRISPR babies” in China made international news, there is much more to the story of CRISPR than headlines seemingly ripped from science fiction. In Editing Humanity, Davies sheds light on the implications that this new technology can have on our everyday lives and in the lives of generations to come.
Author: Anjanabha Bhattacharya
Publisher: Springer Nature
ISBN: 3030420221
Category : Science
Languages : en
Pages : 232
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Book Description
This book offers a comprehensive collection of papers on CRISPR/Cas genome editing in connection with agriculture, climate-smart crops, food security, translational research applications, bioinformatics analysis, practical applications in cereals, floriculture crops, engineering plants for abiotic stress resistance, the intellectual landscape, regulatory framework, and policy decisions. Gathering contributions by internationally respected experts in the field of CRISPR/Cas genome editing, the book offers an essential guide for researchers, students, teachers and scientists in academia; policymakers; and public companies, private companies and cooperatives interested in understanding and/or applying CRISPR/Cas genome editing to develop new agricultural products.
