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Author: Robert Vink
Publisher: University of Adelaide Press
ISBN: 0987073052
Category : Medical
Languages : en
Pages : 354
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Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author: Robert Vink
Publisher: University of Adelaide Press
ISBN: 0987073052
Category : Medical
Languages : en
Pages : 354
Get Book Here
Book Description
The brain is the most complex organ in our body. Indeed, it is perhaps the most complex structure we have ever encountered in nature. Both structurally and functionally, there are many peculiarities that differentiate the brain from all other organs. The brain is our connection to the world around us and by governing nervous system and higher function, any disturbance induces severe neurological and psychiatric disorders that can have a devastating effect on quality of life. Our understanding of the physiology and biochemistry of the brain has improved dramatically in the last two decades. In particular, the critical role of cations, including magnesium, has become evident, even if incompletely understood at a mechanistic level. The exact role and regulation of magnesium, in particular, remains elusive, largely because intracellular levels are so difficult to routinely quantify. Nonetheless, the importance of magnesium to normal central nervous system activity is self-evident given the complicated homeostatic mechanisms that maintain the concentration of this cation within strict limits essential for normal physiology and metabolism. There is also considerable accumulating evidence to suggest alterations to some brain functions in both normal and pathological conditions may be linked to alterations in local magnesium concentration. This book, containing chapters written by some of the foremost experts in the field of magnesium research, brings together the latest in experimental and clinical magnesium research as it relates to the central nervous system. It offers a complete and updated view of magnesiums involvement in central nervous system function and in so doing, brings together two main pillars of contemporary neuroscience research, namely providing an explanation for the molecular mechanisms involved in brain function, and emphasizing the connections between the molecular changes and behavior. It is the untiring efforts of those magnesium researchers who have dedicated their lives to unraveling the mysteries of magnesiums role in biological systems that has inspired the collation of this volume of work.
Author: Milton Abramowitz
Publisher: Courier Corporation
ISBN: 9780486612720
Category : Mathematics
Languages : en
Pages : 1068
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Book Description
An extensive summary of mathematical functions that occur in physical and engineering problems
Author: John P. Klein
Publisher: Springer Science & Business Media
ISBN: 1475727283
Category : Medical
Languages : en
Pages : 508
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Book Description
Making complex methods more accessible to applied researchers without an advanced mathematical background, the authors present the essence of new techniques available, as well as classical techniques, and apply them to data. Practical suggestions for implementing the various methods are set off in a series of practical notes at the end of each section, while technical details of the derivation of the techniques are sketched in the technical notes. This book will thus be useful for investigators who need to analyse censored or truncated life time data, and as a textbook for a graduate course in survival analysis, the only prerequisite being a standard course in statistical methodology.
Author: Mehdi Khosrow-Pour
Publisher: IGI Global Snippet
ISBN: 9781605660264
Category : Computers
Languages : en
Pages : 4292
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Book Description
"This set of books represents a detailed compendium of authoritative, research-based entries that define the contemporary state of knowledge on technology"--Provided by publisher.
Author: Leslie H. Breden
Publisher:
ISBN:
Category : Plastics
Languages : en
Pages : 458
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Book Description
Author: Cresson H. Kearny
Publisher: Skyhorse
ISBN: 1510702059
Category : Medical
Languages : en
Pages : 320
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Book Description
A field-tested guide to surviving a nuclear attack, written by a revered civil defense expert. This edition of Cresson H. Kearny’s iconic Nuclear War Survival Skills (originally published in 1979), updated by Kearny himself in 1987 and again in 2001, offers expert advice for ensuring your family’s safety should the worst come to pass. Chock-full of practical instructions and preventative measures, Nuclear War Survival Skills is based on years of meticulous scientific research conducted by Oak Ridge National Laboratory. Featuring a new introduction by ex-Navy SEAL Don Mann, this book also includes: instructions for six different fallout shelters, myths and facts about the dangers of nuclear weapons, tips for maintaining an adequate food and water supply, a foreword by “the father of the hydrogen bomb,” physicist Dr. Edward Teller, and an “About the Author” note by Eugene P. Wigner, physicist and Nobel Laureate. Written at a time when global tensions were at their peak, Nuclear War Survival Skills remains relevant in the dangerous age in which we now live.
Author: Michael B. Smith
Publisher: John Wiley & Sons
ISBN: 0470084944
Category : Science
Languages : en
Pages : 2379
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Book Description
The Sixth Edition of a classic in organic chemistry continues its tradition of excellence Now in its sixth edition, March's Advanced Organic Chemistry remains the gold standard in organic chemistry. Throughout its six editions, students and chemists from around the world have relied on it as an essential resource for planning and executing synthetic reactions. The Sixth Edition brings the text completely current with the most recent organic reactions. In addition, the references have been updated to enable readers to find the latest primary and review literature with ease. New features include: More than 25,000 references to the literature to facilitate further research Revised mechanisms, where required, that explain concepts in clear modern terms Revisions and updates to each chapter to bring them all fully up to date with the latest reactions and discoveries A revised Appendix B to facilitate correlating chapter sections with synthetic transformations
Author: María Marta Ferreyra
Publisher: World Bank Publications
ISBN: 146481015X
Category : Education
Languages : en
Pages : 387
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Book Description
"Higher education in Latin America and the Caribbean has expanded dramatically in the past 15 years, as the average gross enrollment rate has more than doubled, and many new institutions and programs have been opened. Although higher education access has become more equitable, and higher education supply has become more varied, many of the 'new' students in the system are, on average, less academically ready than are their more advantaged counterparts. Furthermore, only half of higher education students, on average, complete their degree, and labor market returns to higher education vary greatly across institutions and programs. Thus, higher education is at a crossroads today. Given the region's urgency to raise productivity in a low-growth, fiscally constrained environment, going past this crossroads requires the formation of skilled human capital fast and efficiently. 'At a Crossroads: Higher Education in Latin America and the Caribbean' contributes to the discussion by studying quality, variety, and equity of higher education in Latin America and the Caribbean. The book presents comprehensive evidence on the recent higher education expansion and evolution of higher education labor market returns. Using novel data and state-of-the-art methods, it studies demand and supply drivers of the recent expansion. It investigates the behavior of institutions and students and explores the unintended consequences of large-scale higher education policies. Framing the analysis are the singular characteristics of the higher education market and the market segmentation induced by the variety of students and institutions in the system. At this crossroads, a role emerges for incentives, information, accountability, and choice."
Author: Allen B. Downey
Publisher: "O'Reilly Media, Inc."
ISBN: 1449331696
Category : Computers
Languages : en
Pages : 159
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Book Description
Expand your Python skills by working with data structures and algorithms in a refreshing context—through an eye-opening exploration of complexity science. Whether you’re an intermediate-level Python programmer or a student of computational modeling, you’ll delve into examples of complex systems through a series of exercises, case studies, and easy-to-understand explanations. You’ll work with graphs, algorithm analysis, scale-free networks, and cellular automata, using advanced features that make Python such a powerful language. Ideal as a text for courses on Python programming and algorithms, Think Complexity will also help self-learners gain valuable experience with topics and ideas they might not encounter otherwise. Work with NumPy arrays and SciPy methods, basic signal processing and Fast Fourier Transform, and hash tables Study abstract models of complex physical systems, including power laws, fractals and pink noise, and Turing machines Get starter code and solutions to help you re-implement and extend original experiments in complexity Explore the philosophy of science, including the nature of scientific laws, theory choice, realism and instrumentalism, and other topics Examine case studies of complex systems submitted by students and readers
Author: W. Joost Wiersinga
Publisher: Springer
ISBN: 3319735063
Category : Medical
Languages : en
Pages : 264
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Book Description
This practically oriented book provides an up-to-date overview of all significant aspects of the pathogenesis of sepsis and its management, including within the intensive care unit. Readers will find information on the involvement of the coagulation and endocrine systems during sepsis and on the use of biomarkers to diagnose sepsis and allow early intervention. International clinical practice guidelines for the management of sepsis are presented, and individual chapters focus on aspects such as fluid resuscitation, vasopressor therapy, response to multiorgan failure, antimicrobial therapy, and adjunctive immunotherapy. The closing section looks forward to the coming decade, discussing novel trial designs, sepsis in low- and middle-income countries, and emerging management approaches. The book is internatio nal in scope, with contributions from leading experts worldwide. It will be of value to residents and professionals/practitioners in the fields of infectious diseases and internal medicine, as well as to GPs and medical students.
