Author: Rabah Boukherroub
Publisher: William Andrew
ISBN: 032341737X
Category : Science
Languages : en
Pages : 339
Book Description
Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance introduces the reader to the newly developing use of nanotechnology to combat microbial drug resistance. Excessive use of antibiotics and antimicrobial agents has produced an inexorable rise in antibiotic resistance in bacterial pathogens. The use of nanotechnology is currently the most promising strategy to overcome microbial drug resistance. This book shows how, due to their small size, nanoparticles can surmount existing drug resistance mechanisms, including decreased uptake and increased efflux of the drug from the microbial cell, biofilm formation, and intracellular bacteria. In particular, chapters cover the use of nanoparticles to raise intracellular antimicrobial levels, thus directly targeting sites of infection and packaging multiple antimicrobial agents onto a single nanoparticle. - Provides the information users need to integrate antibacterial nanoparticles into future treatments - Gives readers with backgrounds in nanotechnology, chemistry, and materials science an understanding of the main issues concerning microbial drug resistance and its challenges - Includes real-life case studies that illustrates how functionalized nanomaterials are used to manage microbial infection
Functionalized Nanomaterials for the Management of Microbial Infection
Author: Rabah Boukherroub
Publisher: William Andrew
ISBN: 032341737X
Category : Science
Languages : en
Pages : 339
Book Description
Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance introduces the reader to the newly developing use of nanotechnology to combat microbial drug resistance. Excessive use of antibiotics and antimicrobial agents has produced an inexorable rise in antibiotic resistance in bacterial pathogens. The use of nanotechnology is currently the most promising strategy to overcome microbial drug resistance. This book shows how, due to their small size, nanoparticles can surmount existing drug resistance mechanisms, including decreased uptake and increased efflux of the drug from the microbial cell, biofilm formation, and intracellular bacteria. In particular, chapters cover the use of nanoparticles to raise intracellular antimicrobial levels, thus directly targeting sites of infection and packaging multiple antimicrobial agents onto a single nanoparticle. - Provides the information users need to integrate antibacterial nanoparticles into future treatments - Gives readers with backgrounds in nanotechnology, chemistry, and materials science an understanding of the main issues concerning microbial drug resistance and its challenges - Includes real-life case studies that illustrates how functionalized nanomaterials are used to manage microbial infection
Publisher: William Andrew
ISBN: 032341737X
Category : Science
Languages : en
Pages : 339
Book Description
Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance introduces the reader to the newly developing use of nanotechnology to combat microbial drug resistance. Excessive use of antibiotics and antimicrobial agents has produced an inexorable rise in antibiotic resistance in bacterial pathogens. The use of nanotechnology is currently the most promising strategy to overcome microbial drug resistance. This book shows how, due to their small size, nanoparticles can surmount existing drug resistance mechanisms, including decreased uptake and increased efflux of the drug from the microbial cell, biofilm formation, and intracellular bacteria. In particular, chapters cover the use of nanoparticles to raise intracellular antimicrobial levels, thus directly targeting sites of infection and packaging multiple antimicrobial agents onto a single nanoparticle. - Provides the information users need to integrate antibacterial nanoparticles into future treatments - Gives readers with backgrounds in nanotechnology, chemistry, and materials science an understanding of the main issues concerning microbial drug resistance and its challenges - Includes real-life case studies that illustrates how functionalized nanomaterials are used to manage microbial infection
Nanostructures for Antimicrobial Therapy
Author: Anton Ficai
Publisher: Elsevier
ISBN: 0323461514
Category : Science
Languages : en
Pages : 724
Book Description
Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. - Shows how nanoantibiotics can be used to more effectively treat disease - Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs - Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area
Publisher: Elsevier
ISBN: 0323461514
Category : Science
Languages : en
Pages : 724
Book Description
Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. - Shows how nanoantibiotics can be used to more effectively treat disease - Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs - Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area
Bioengineered Nanomaterials for Wound Healing and Infection Control
Author: Hamed Barabadi
Publisher: Elsevier
ISBN: 0323958354
Category : Technology & Engineering
Languages : en
Pages : 591
Book Description
Bioengineered Nanomaterials for Wound Healing and Infection Control is a key reference for those working in the fields of materials science, pharmacy, nanotechnology, biomedical engineering and microbiology. Bioengineered nanomaterials have unique physicochemical properties which promote accelerated wound healing and treatment of infections. The biosynthesis of these nanomaterials also offers a clean, safe and renewable alternative to traditional nanomaterials, helping reduce environmental impact alongside antibacterial resistance. - Provides an overview of the role of biofilms and multidrug resistance in wound infections - Covers a range of bioengineered nanomaterial types and nanotechnology-based approaches, including phyconanotechnology, phytonanotechnology and microbial nanotechnology - Helps readers discover novel materials for use in wound healing and infection control while reducing the probability of antibiotic resistance
Publisher: Elsevier
ISBN: 0323958354
Category : Technology & Engineering
Languages : en
Pages : 591
Book Description
Bioengineered Nanomaterials for Wound Healing and Infection Control is a key reference for those working in the fields of materials science, pharmacy, nanotechnology, biomedical engineering and microbiology. Bioengineered nanomaterials have unique physicochemical properties which promote accelerated wound healing and treatment of infections. The biosynthesis of these nanomaterials also offers a clean, safe and renewable alternative to traditional nanomaterials, helping reduce environmental impact alongside antibacterial resistance. - Provides an overview of the role of biofilms and multidrug resistance in wound infections - Covers a range of bioengineered nanomaterial types and nanotechnology-based approaches, including phyconanotechnology, phytonanotechnology and microbial nanotechnology - Helps readers discover novel materials for use in wound healing and infection control while reducing the probability of antibiotic resistance
Antibiotic Drug Resistance
Author: José-Luis Capelo-Martínez
Publisher: John Wiley & Sons
ISBN: 1119282527
Category : Medical
Languages : en
Pages : 730
Book Description
This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Publisher: John Wiley & Sons
ISBN: 1119282527
Category : Medical
Languages : en
Pages : 730
Book Description
This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies
Functionalized Nanomaterials for Biosensing and Bioelectronics Applications
Author: Sudheesh K. Shukla
Publisher: Woodhead Publishing
ISBN: 0128238437
Category : Technology & Engineering
Languages : en
Pages : 378
Book Description
Functionalized Nanomaterials for Biosensing and Bioelectronics Applications: Trends and Challenges describes current and future opportunities for integrating the unique properties of two-dimensional nanomaterials with bioelectronic interfaces. Sections focus on background information and fundamental concepts, review the available functionalized nanomaterials and their properties, explore the integration of functionalized nanomaterials with bioelectronics, including available fabrication and characterization methods, electrical behavior at the interface, and design and synthesis guidelines, and review examples of microsystems where functionalized nanomaterials are being integrated with bioelectronics. This book is suitable for researchers and practitioners in academia and R&D working in materials science and engineering, analytical chemistry and related fields. - Introduces the most common functionalized nanomaterials and their morphologies, properties, and mechanisms for sensing applications - Reviews functionalization and fabrication methods and techniques for the integration of one- and two-dimensional materials for sensing applications - Addresses the most relevant applications of functionalized nanomaterials for biosensing and bioelectronics applications
Publisher: Woodhead Publishing
ISBN: 0128238437
Category : Technology & Engineering
Languages : en
Pages : 378
Book Description
Functionalized Nanomaterials for Biosensing and Bioelectronics Applications: Trends and Challenges describes current and future opportunities for integrating the unique properties of two-dimensional nanomaterials with bioelectronic interfaces. Sections focus on background information and fundamental concepts, review the available functionalized nanomaterials and their properties, explore the integration of functionalized nanomaterials with bioelectronics, including available fabrication and characterization methods, electrical behavior at the interface, and design and synthesis guidelines, and review examples of microsystems where functionalized nanomaterials are being integrated with bioelectronics. This book is suitable for researchers and practitioners in academia and R&D working in materials science and engineering, analytical chemistry and related fields. - Introduces the most common functionalized nanomaterials and their morphologies, properties, and mechanisms for sensing applications - Reviews functionalization and fabrication methods and techniques for the integration of one- and two-dimensional materials for sensing applications - Addresses the most relevant applications of functionalized nanomaterials for biosensing and bioelectronics applications
Principles and Applications of Antimicrobial Nanomaterials
Author: Joseph L. Graves Jr
Publisher: Elsevier
ISBN: 0128232633
Category : Technology & Engineering
Languages : en
Pages : 345
Book Description
Principles and Applications of Antimicrobial Nanomaterials introduces the reader to the microbial world, antimicrobial nanomaterials, how microbial evolution works, and how knowledge of these areas can facilitate the development of sustainable antimicrobials. Due to the widespread occurrence of multidrug-resistant microbes, there is an increasing interest in the use of novel nanostructured materials as antimicrobials. This book is designed to help researchers from fields such as materials science, nanoscience, and nanoengineering who are attempting to develop these antimicrobial materials. - Provides crucial background in microbiology and microbial evolution to help researchers design experiments that can produce sustainable results - Offers detailed coverage on the antimicrobial properties of different types of nanomaterials - Discusses the major challenges of using nanomaterials for antimicrobial applications
Publisher: Elsevier
ISBN: 0128232633
Category : Technology & Engineering
Languages : en
Pages : 345
Book Description
Principles and Applications of Antimicrobial Nanomaterials introduces the reader to the microbial world, antimicrobial nanomaterials, how microbial evolution works, and how knowledge of these areas can facilitate the development of sustainable antimicrobials. Due to the widespread occurrence of multidrug-resistant microbes, there is an increasing interest in the use of novel nanostructured materials as antimicrobials. This book is designed to help researchers from fields such as materials science, nanoscience, and nanoengineering who are attempting to develop these antimicrobial materials. - Provides crucial background in microbiology and microbial evolution to help researchers design experiments that can produce sustainable results - Offers detailed coverage on the antimicrobial properties of different types of nanomaterials - Discusses the major challenges of using nanomaterials for antimicrobial applications
Preclinical Evaluation of Antimicrobial Nanodrugs
Author: Juan Bueno
Publisher: Springer Nature
ISBN: 3030438554
Category : Medical
Languages : en
Pages : 125
Book Description
Translational medicine addresses the gap between research and the clinical application of new discoveries. To efficiently deliver new drugs to care centers, a preclinical evaluation, both in vitro and in vivo, is required to ensure that the most active and least toxic compounds are selected as well as to predict clinical outcome. Antimicrobial nanomedicines have been shown to have higher specificity in their therapeutic targets and the ability to serve as adjuvants, increasing the effectiveness of pre-existing immune compounds. The design and development of new standardized protocols for evaluating antimicrobial nanomedicines is needed for both the industry and clinical laboratory. These protocols must aim to evaluate laboratory activity and present models of pharmacokinetic-pharmacodynamic and toxicokinetic behavior that predict absorption and distribution. Likewise, these protocols must follow a theranostics approach, be able to detect promising formulations, diagnose the infectious disease, and determine the correct treatment to implement a personalized therapeutic behavior. Given the possibilities that nanotechnology offers, not updating to new screening platforms is inadequate as it prevents the correct application of discoveries, increasing the effect of the valley of death between innovations and their use. This book is structured to discuss the fundamentals taken into account for the design of robust, reproducible and automatable evaluation platforms. These vital platforms should enable the discovery of new medicines with which to face antimicrobial resistance (RAM), one of the great problems of our time.
Publisher: Springer Nature
ISBN: 3030438554
Category : Medical
Languages : en
Pages : 125
Book Description
Translational medicine addresses the gap between research and the clinical application of new discoveries. To efficiently deliver new drugs to care centers, a preclinical evaluation, both in vitro and in vivo, is required to ensure that the most active and least toxic compounds are selected as well as to predict clinical outcome. Antimicrobial nanomedicines have been shown to have higher specificity in their therapeutic targets and the ability to serve as adjuvants, increasing the effectiveness of pre-existing immune compounds. The design and development of new standardized protocols for evaluating antimicrobial nanomedicines is needed for both the industry and clinical laboratory. These protocols must aim to evaluate laboratory activity and present models of pharmacokinetic-pharmacodynamic and toxicokinetic behavior that predict absorption and distribution. Likewise, these protocols must follow a theranostics approach, be able to detect promising formulations, diagnose the infectious disease, and determine the correct treatment to implement a personalized therapeutic behavior. Given the possibilities that nanotechnology offers, not updating to new screening platforms is inadequate as it prevents the correct application of discoveries, increasing the effect of the valley of death between innovations and their use. This book is structured to discuss the fundamentals taken into account for the design of robust, reproducible and automatable evaluation platforms. These vital platforms should enable the discovery of new medicines with which to face antimicrobial resistance (RAM), one of the great problems of our time.
Nanotechnology Applied To Pharmaceutical Technology
Author: Mahendra Rai
Publisher: Springer
ISBN: 3319702998
Category : Medical
Languages : en
Pages : 388
Book Description
Focusing on the application of nanotechnology in pharmaceutical technology the editors seek to integrate the two in order to obtain innovative products and solutions in pharmacology. Interdisciplinary in content it is of interest to those who are involved in the development of nanoproducts including nanotechnologists, microbiologists, biotechnologists pharmacologists and clinicians. Recent studies are presented that include the biosynthesis of nanoparticles focusing on antimicrobials; nanomaterial-based formulations that treat cancer, infections, skin disorders and wounds;nanomaterials in eye diseases and toxicity and safety issues. It demonstrates the crucial role this plays in tackling multi-drug resistant threats.
Publisher: Springer
ISBN: 3319702998
Category : Medical
Languages : en
Pages : 388
Book Description
Focusing on the application of nanotechnology in pharmaceutical technology the editors seek to integrate the two in order to obtain innovative products and solutions in pharmacology. Interdisciplinary in content it is of interest to those who are involved in the development of nanoproducts including nanotechnologists, microbiologists, biotechnologists pharmacologists and clinicians. Recent studies are presented that include the biosynthesis of nanoparticles focusing on antimicrobials; nanomaterial-based formulations that treat cancer, infections, skin disorders and wounds;nanomaterials in eye diseases and toxicity and safety issues. It demonstrates the crucial role this plays in tackling multi-drug resistant threats.
Hydrogels Based on Natural Polymers
Author: Yu Chen
Publisher: Elsevier
ISBN: 0128166185
Category : Technology & Engineering
Languages : en
Pages : 553
Book Description
Hydrogels Based on Natural Polymers presents the latest research on natural polymer-based hydrogels, covering fundamentals, preparation methods, synthetic pathways, advanced properties, major application areas, and novel characterization techniques. The advantages and disadvantages of each natural polymer-based hydrogel are also discussed, enabling preparation tactics for specific properties and applications. Sections cover fundamentals, development, characteristics, structures and properties. Additional chapters cover presentation methods and properties based on natural polymers, including physical and chemical properties, stimuli-responsive properties, self-healing properties, and biological properties. The final section presents major applications areas, including the biomedical field, agriculture, water treatments, and the food industry. This is a highly valuable resource for academic researchers, scientists and advanced students working with hydrogels and natural polymers, as well as across the fields of polymer science, polymer chemistry, plastics engineering, biopolymers and biomaterials. The detailed information will also be of great interest to scientists and R&D professionals, product designers, technicians and engineers across industries. - Provides systematic coverage of all aspects of hydrogels based on natural polymers, including fundamentals, preparation methods, properties and characterization - Offers a balanced assessment of the specific properties and possibilities offered by different natural polymer-based hydrogels, drawing on innovative research - Examines cutting-edge applications across biomedicine, agriculture, water treatments, and the food industry
Publisher: Elsevier
ISBN: 0128166185
Category : Technology & Engineering
Languages : en
Pages : 553
Book Description
Hydrogels Based on Natural Polymers presents the latest research on natural polymer-based hydrogels, covering fundamentals, preparation methods, synthetic pathways, advanced properties, major application areas, and novel characterization techniques. The advantages and disadvantages of each natural polymer-based hydrogel are also discussed, enabling preparation tactics for specific properties and applications. Sections cover fundamentals, development, characteristics, structures and properties. Additional chapters cover presentation methods and properties based on natural polymers, including physical and chemical properties, stimuli-responsive properties, self-healing properties, and biological properties. The final section presents major applications areas, including the biomedical field, agriculture, water treatments, and the food industry. This is a highly valuable resource for academic researchers, scientists and advanced students working with hydrogels and natural polymers, as well as across the fields of polymer science, polymer chemistry, plastics engineering, biopolymers and biomaterials. The detailed information will also be of great interest to scientists and R&D professionals, product designers, technicians and engineers across industries. - Provides systematic coverage of all aspects of hydrogels based on natural polymers, including fundamentals, preparation methods, properties and characterization - Offers a balanced assessment of the specific properties and possibilities offered by different natural polymer-based hydrogels, drawing on innovative research - Examines cutting-edge applications across biomedicine, agriculture, water treatments, and the food industry
Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases
Author: Mahendra Rai
Publisher: Academic Press
ISBN: 0128014717
Category : Technology & Engineering
Languages : en
Pages : 341
Book Description
Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising avenue for the diagnosis, treatment, and prophylaxis of infectious diseases. - Provides a comprehensive overview of the use of nanotechnology in the treatment and diagnosis of infectious diseases - Covers all common types of infective agents, including bacteria, viruses, fungi, and protozoa, along with their vectors, ticks, mosquitoes, flies, etc. - Delivers commentary from an international researcher base, providing insights across differing economic statuses - Includes a foundation of basic nanotechnological concepts to aid in designing new strategies to combat several pathogenic diseases and cancer - Illustrates the high antimicrobial potential of nanoparticles, ultimately demonstrating how they are a promising alternative class that can be successfully used in fighting a myriad of infections
Publisher: Academic Press
ISBN: 0128014717
Category : Technology & Engineering
Languages : en
Pages : 341
Book Description
Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising avenue for the diagnosis, treatment, and prophylaxis of infectious diseases. - Provides a comprehensive overview of the use of nanotechnology in the treatment and diagnosis of infectious diseases - Covers all common types of infective agents, including bacteria, viruses, fungi, and protozoa, along with their vectors, ticks, mosquitoes, flies, etc. - Delivers commentary from an international researcher base, providing insights across differing economic statuses - Includes a foundation of basic nanotechnological concepts to aid in designing new strategies to combat several pathogenic diseases and cancer - Illustrates the high antimicrobial potential of nanoparticles, ultimately demonstrating how they are a promising alternative class that can be successfully used in fighting a myriad of infections