From Structure to Signalosomes: New Perspectives About Membrane Receptors and Channels

From Structure to Signalosomes: New Perspectives About Membrane Receptors and Channels PDF Author: Yi Ma
Publisher: Frontiers Media SA
ISBN: 288945973X
Category :
Languages : en
Pages : 192

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Book Description

From Structure to Signalosomes: New Perspectives About Membrane Receptors and Channels

From Structure to Signalosomes: New Perspectives About Membrane Receptors and Channels PDF Author: Yi Ma
Publisher: Frontiers Media SA
ISBN: 288945973X
Category :
Languages : en
Pages : 192

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Book Description


Structure and Function of Calcium Release Channels

Structure and Function of Calcium Release Channels PDF Author: Irina Serysheva
Publisher: Academic Press
ISBN: 0123810388
Category : Science
Languages : en
Pages : 389

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Book Description
This volume of Current Topics in Membranes focuses on Membrane Protein Crystallization, beginning with a review of past successes and general trends, then further discussing challenges of mebranes protein crystallization, cell free production of membrane proteins and novel lipids for membrane protein crystallization. This publication also includes tools to enchance membrane protein crystallization, technique advancements, and crystallization strategies used for photosystem I and its complexes, establishing Membrane Protein Crystallization as a needed, practical reference for researchers.

Cumulated Index Medicus

Cumulated Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1808

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Book Description


Store-Operated Calcium Channels

Store-Operated Calcium Channels PDF Author:
Publisher: Academic Press
ISBN: 0124079385
Category : Science
Languages : en
Pages : 307

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Book Description
Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. - The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels - Contributors are authoritative researchers who have produced important advances in the field - The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject

Index Medicus

Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 2324

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Book Description
Vols. for 1963- include as pt. 2 of the Jan. issue: Medical subject headings.

Cardiomyocyte Microdomains: An Emerging Concept of Local Regulation and Remodeling

Cardiomyocyte Microdomains: An Emerging Concept of Local Regulation and Remodeling PDF Author: Alexey V. Glukhov
Publisher: Frontiers Media SA
ISBN: 2889638367
Category :
Languages : en
Pages : 212

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Book Description


Molecular Aspects of G Protein-coupled Receptors

Molecular Aspects of G Protein-coupled Receptors PDF Author: Francisco Ciruela
Publisher: Nova Publishers
ISBN: 9781600219153
Category : Science
Languages : en
Pages : 328

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Book Description
In the recent years, studies based on two-hybrid screens, proteomic, biochemical and cell biology approaches, have shown that intracellular domains of G protein-coupled receptors (GPCR) or heptaspanning membrane receptors (HSMRs) interact with intracellular proteins. These interactions are the basis of a protein network associated to these receptors which includes scaffolding proteins containing one or several PDZ (post-synaptic density-95, discs large, zona occludens-1) domains, signalling proteins and proteins of the cytoskeleton. The present book is focused on the emerging evidence for interactions of G protein-coupled receptors with scaffolding, cytoskeletal and signalling proteins that will play a role in the targeting, anchoring and functioning of these receptors in the plasma membrane, thus contributing to cell development and plasticity.

Calcium Entry Channels in Non-Excitable Cells

Calcium Entry Channels in Non-Excitable Cells PDF Author: Juliusz Ashot Kozak
Publisher: CRC Press
ISBN: 149875273X
Category : Science
Languages : en
Pages : 343

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Book Description
Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.

Frontiers in the Pharmacological Manipulation of Intracellular cAMP Levels

Frontiers in the Pharmacological Manipulation of Intracellular cAMP Levels PDF Author: George S. Baillie
Publisher: Frontiers Media SA
ISBN: 2889198154
Category : Science (General)
Languages : en
Pages : 193

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Book Description
Cyclic adenosine monophosphate (cAMP) is a second messenger of paramount biological importance, involved in the regulation of a significant number of cellular functions through the cAMP-dependent intracellular signal transduction pathways. The aim of this "Frontiers in Pharmacology" Research Topic was to attract contributions that highlight emerging ideas in the cAMP field that: (i) describe its role in cellular function and homeostasis, (ii) present the current approaches to its pharmacological manipulation, and (iii) clarify its central role in the development of more targeted therapeutic approaches toward a spectrum of diseases. The present collection of articles highlights, in a representative (but certainly not exhaustive) way, the research activity and emerging concepts in the field, while it also reveals the therapeutic potential that targeted pharmacological manipulation of intracellular cAMP levels could exert on a number of pathological conditions.

Macromolecular Protein Complexes III: Structure and Function

Macromolecular Protein Complexes III: Structure and Function PDF Author: J. Robin Harris
Publisher: Springer Nature
ISBN: 3030589714
Category : Science
Languages : en
Pages : 580

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Book Description
This book covers important topics such as the dynamic structure and function of the 26S proteasome, the DNA replication machine: structure and dynamic function and the structural organization and protein–protein interactions in the human adenovirus capsid, to mention but a few. The 18 chapters included here, written by experts in their specific field, are at the forefront of scientific knowledge. The impressive integration of structural data from X-ray crystallography with that from cryo-electron microscopy is apparent throughout the book. In addition, functional aspects are also given a high priority. Chapter 1 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.