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Author: George G. Brownlee
Publisher: Cambridge University Press
ISBN: 1316124053
Category : Science
Languages : en
Pages : 315
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Book Description
Considered 'the father of genomics', Fred Sanger (1918–2013) paved the way for the modern revolution in our understanding of biology. His pioneering methods for sequencing proteins, RNA and, eventually, DNA earned him two Nobel Prizes. He remains one of only four scientists (and the only British scientist) ever to have achieved that distinction. In this, the first full biography of Fred Sanger to be published, Brownlee traces Sanger's life from his birth in rural Gloucestershire to his retirement in 1983 from the Medical Research Council's Laboratory of Molecular Biology in Cambridge. Along the way, he highlights the remarkable extent of Sanger's scientific achievements and provides a real portrait of the modest man behind them. Including an extensive transcript of a rare interview of Sanger by the author, this biography also considers the wider legacy of Sanger's work, including his impact on the Human Genome Project and beyond.
Author: George G. Brownlee
Publisher: Cambridge University Press
ISBN: 1316124053
Category : Science
Languages : en
Pages : 315
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Book Description
Considered 'the father of genomics', Fred Sanger (1918–2013) paved the way for the modern revolution in our understanding of biology. His pioneering methods for sequencing proteins, RNA and, eventually, DNA earned him two Nobel Prizes. He remains one of only four scientists (and the only British scientist) ever to have achieved that distinction. In this, the first full biography of Fred Sanger to be published, Brownlee traces Sanger's life from his birth in rural Gloucestershire to his retirement in 1983 from the Medical Research Council's Laboratory of Molecular Biology in Cambridge. Along the way, he highlights the remarkable extent of Sanger's scientific achievements and provides a real portrait of the modest man behind them. Including an extensive transcript of a rare interview of Sanger by the author, this biography also considers the wider legacy of Sanger's work, including his impact on the Human Genome Project and beyond.
Author: Joe S. Jeffers
Publisher: Springer
ISBN: 3319547097
Category : Science
Languages : en
Pages : 94
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Book Description
In this Brief, Joe Jeffers uncovers the life and works of two-time Nobel Laureate Frederick Sanger. Following Sanger’s early life to retirement, Jeffers describes how this celebrated British biochemist became the first person to determine the amino acid sequence of a protein for which he was awarded the Nobel Prize in 1958. Highlighting Sanger’s remarkable career, Jeffers describes Sanger’s later change in research direction to investigate deoxyribonucleic acids (DNA), work for which Sanger also received the Nobel Prize jointly with Paul Berg and Walter Gilbert in 1980. Joe Jeffers conducted twelve interviews with Sanger over the period of 1999-2009 and he has also spoken to more than 40 of Sanger’s colleagues and family members. This brief provides a rigorous yet concise view of Sanger on a personal and scientific level and is suitable for biochemists, historians or the interested layperson.
Author: Soraya de Chadarevian
Publisher: Cambridge University Press
ISBN: 9780521570787
Category : Medical
Languages : en
Pages : 452
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Book Description
An important study on the making of molecular biology and its cultural contexts.
Author: Michael Bliss
Publisher: University of Toronto Press
ISBN: 1487516746
Category : Medical
Languages : en
Pages : 524
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Book Description
The discovery of insulin at the University of Toronto in 1921-22 was one of the most dramatic events in the history of the treatment of disease. Insulin was a wonder-drug with ability to bring patients back from the very brink of death, and it was no surprise that in 1923 the Nobel Prize for Medicine was awarded to its discoverers, the Canadian research team of Banting, Best, Collip, and Macleod. In this engaging and award-winning account, historian Michael Bliss recounts the fascinating story behind the discovery of insulin – a story as much filled with fiery confrontation and intense competition as medical dedication and scientific genius. Originally published in 1982 and updated in 1996, The Discovery of Insulin has won the City of Toronto Book Award, the Jason Hannah Medal of the Royal Society of Canada, and the William H. Welch Medal of the American Association for the History of Medicine.
Author: Colin Ratledge
Publisher: Cambridge University Press
ISBN: 0521840317
Category : Medical
Languages : en
Pages : 653
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Book Description
Biotechnology is one of the major technologies of the twenty-first century. Its wide-ranging, multi-disciplinary activities include recombinant DNA techniques, cloning and the application of microbiology to the production of goods from bread to antibiotics. In this new edition of the textbook Basic Biotechnology, biology and bioprocessing topics are uniquely combined to provide a complete overview of biotechnology. The fundamental principles that underpin all biotechnology are explained and a full range of examples are discussed to show how these principles are applied; from starting substrate to final product. A distinctive feature of this text are the discussions of the public perception of biotechnology and the business of biotechnology, which set the science in a broader context. This comprehensive textbook is essential reading for all students of biotechnology and applied microbiology, and for researchers in biotechnology industries.
Author: Georgina Ferry
Publisher: CSHL Press
ISBN: 0879697857
Category : Biography & Autobiography
Languages : en
Pages : 383
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Book Description
Few scientists have thought more deeply about the nature of their calling and its impact on humanity than Max Perutz (1914–2002). Born in Vienna, Jewish by descent, lapsed Catholic by religion, he came to Cambridge in 1936 to join the lab of the legendary Communist thinker J.D. Bernal. There he began to explore the structures of the molecules that hold the secret of life. In 1940, he was interned and deported to Canada as an enemy alien, only to be brought back and set to work on a bizarre top secret war project. In 1947, he founded the small research group in which Francis Crick and James Watson discovered the structure of DNA: under his leadership it grew to become the world–famous Laboratory for Molecular Biology. Max himself explored the protein hemoglobin and his work, which won him a Nobel Prize in 1962, launched a new era of medicine, heralding today's astonishing advances in the genetic basis of disease. Max Perutz's story, wonderfully told by Georgina Ferry, brims with life. It has the zest of an adventure novel and is full of extraordinary characters. Max was demanding, passionate and driven but also humorous, compassionate and loving. Small in stature, he became a fearless mountain climber; drawing on his own experience as a refugee, he argued fearlessly for human rights; he could be ruthless but had a talent for friendship. An articulate and engaging advocate of science, he found new problems to engage his imagination until weeks before he died aged 88. About the author: Georgina Ferry is a former staff editor on New Scientist,and contributor to BBC Radio 4's Science Now.Her books include the acclaimed biography Dorothy Hodgkin: A Life(1998); The Common Thread(2002, with Sir John Sulston); and A Computer Called LEO(2003). She lives in Oxford.
Author: Andreas Hofmann
Publisher: Cambridge University Press
ISBN: 1108365256
Category : Science
Languages : en
Pages : 962
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Book Description
Bringing this best-selling textbook right up to date, the new edition uniquely integrates the theories and methods that drive the fields of biology, biotechnology and medicine, comprehensively covering both the techniques students will encounter in lab classes and those that underpin current key advances and discoveries. The contents have been updated to include both traditional and cutting-edge techniques most commonly used in current life science research. Emphasis is placed on understanding the theory behind the techniques, as well as analysis of the resulting data. New chapters cover proteomics, genomics, metabolomics, bioinformatics, as well as data analysis and visualisation. Using accessible language to describe concepts and methods, and with a wealth of new in-text worked examples to challenge students' understanding, this textbook provides an essential guide to the key techniques used in current bioscience research.
Author: Haian Fu
Publisher: Cambridge University Press
ISBN: 1107377587
Category : Science
Languages : en
Pages : 359
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Book Description
Advances in chemistry, biology and genomics coupled with laboratory automation and computational technologies have led to the rapid emergence of the multidisciplinary field of chemical genomics. This edited text, with contributions from experts in the field, discusses the new techniques and applications that help further the study of chemical genomics. The beginning chapters provide an overview of the basic principles of chemical biology and chemical genomics. This is followed by a technical section that describes the sources of small-molecule chemicals; the basics of high-throughput screening technologies; and various bioassays for biochemical-, cellular- and organism-based screens. The final chapters connect the chemical genomics field with personalized medicine and the druggable genome for future discovery of new therapeutics. This book will be valuable to researchers, professionals and graduate students in many fields, including biology, biomedicine and chemistry.
Author: Christopher Howe
Publisher: Cambridge University Press
ISBN: 1139463586
Category : Medical
Languages : en
Pages : 250
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Book Description
Updated to reflect advances in the field, this introduction provides a broad, but concise, coverage of recombinant DNA techniques. Written for advanced undergraduates, graduates and scientists who want to use this technology, emphasis is placed on the concepts underlying particular types of cloning vectors to aid understanding and to enable readers to devise suitable strategies for novel experimental situations. An introduction to the basic biochemical principles is presented first. Then PCR and cloning using E. coli hosts and plasmid, phage and hybrid vectors are described, followed by the generation and screening of libraries and how to modify, inactivate or express cloned sequences. Finally genetic manipulation in a range of other organisms is discussed, including other bacteria, fungi, algae and plants, insects and mammals. A series of 'real-life' biological problems are also presented to enable readers to assess their understanding of the material and to prepare for exams.
Author: J. Craig Venter
Publisher: Penguin
ISBN: 1101202564
Category : Biography & Autobiography
Languages : en
Pages : 424
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Book Description
The triumphant memoir of the man behind one of the greatest feats in scientific history Of all the scientific achievements of the past century, perhaps none can match the deciphering of the human genetic code, both for its technical brilliance and for its implications for our future. In A Life Decoded, J. Craig Venter traces his rise from an uninspired student to one of the most fascinating and controversial figures in science today. Here, Venter relates the unparalleled drama of the quest to decode the human genome?a goal he predicted he could achieve years earlier and more cheaply than the government-sponsored Human Genome Project, and one that he fulfilled in 2001. A thrilling story of detection, A Life Decoded is also a revealing, and often troubling, look at how science is practiced today.
