Author: Behnam Sadeghi
Publisher: Elsevier
ISBN: 0323908985
Category : Science
Languages : en
Pages : 304
Book Description
Fractals and Multifractals in the Geosciences details the application of a wide range of multifractal methods, including many novel ones developed by the author, along with the assessment of uncertainty in sample classification and stability of spatial patterns. This book also provides criteria for selection of the most effective combination of data pre-processing and multifractal modeling to extract desired features or signals in the data. The book specifically aims to introduce, apply, and test novel multifractal models that account directly for changes in relationships between variables, as well as the effects of distance between samples and the source of anomalous metal contents in geoscience samples. Linked to this will be assessment of the effects of different pre-processing of data prior to application of the models and quantification/model uncertainty in geochemical anomaly maps, associated with sample classification and spatial interpolation. Gaussian simulations such as Sequential Gaussian Simulation and Monte Carlo Simulation will be applied to the new multifractal models developed and a suite of existing models, including (simulated) concentration-area, spectrum-area, singularity and other models. Fractals and Multifractals in the Geosciences will be invaluable for mathematical geoscientists, geostatisticians, exploration, applied, urban and environmental geochemists, computational geoscientists, data scientists, and GIS professionals who need to better understand fractal geometry, along with its theory and applications in geochemical anomaly classification to generate maps that are helpful for decision-making for follow-up sampling and explorations. - Provides a comprehensive overview of the use of fractal and multifractal modeling methods, with a detailed assessment of uncertainty quantification in samples and classified models - Specifically includes novel multifractal models, as well as uncertainty quantification and decision-making methods for use in geosciences and especially geochemistry - Includes case studies showing the application of the fractal and multifractal methods detailed in the book
Fractals and Multifractals in the Geosciences
Author: Behnam Sadeghi
Publisher: Elsevier
ISBN: 0323908985
Category : Science
Languages : en
Pages : 304
Book Description
Fractals and Multifractals in the Geosciences details the application of a wide range of multifractal methods, including many novel ones developed by the author, along with the assessment of uncertainty in sample classification and stability of spatial patterns. This book also provides criteria for selection of the most effective combination of data pre-processing and multifractal modeling to extract desired features or signals in the data. The book specifically aims to introduce, apply, and test novel multifractal models that account directly for changes in relationships between variables, as well as the effects of distance between samples and the source of anomalous metal contents in geoscience samples. Linked to this will be assessment of the effects of different pre-processing of data prior to application of the models and quantification/model uncertainty in geochemical anomaly maps, associated with sample classification and spatial interpolation. Gaussian simulations such as Sequential Gaussian Simulation and Monte Carlo Simulation will be applied to the new multifractal models developed and a suite of existing models, including (simulated) concentration-area, spectrum-area, singularity and other models. Fractals and Multifractals in the Geosciences will be invaluable for mathematical geoscientists, geostatisticians, exploration, applied, urban and environmental geochemists, computational geoscientists, data scientists, and GIS professionals who need to better understand fractal geometry, along with its theory and applications in geochemical anomaly classification to generate maps that are helpful for decision-making for follow-up sampling and explorations. - Provides a comprehensive overview of the use of fractal and multifractal modeling methods, with a detailed assessment of uncertainty quantification in samples and classified models - Specifically includes novel multifractal models, as well as uncertainty quantification and decision-making methods for use in geosciences and especially geochemistry - Includes case studies showing the application of the fractal and multifractal methods detailed in the book
Publisher: Elsevier
ISBN: 0323908985
Category : Science
Languages : en
Pages : 304
Book Description
Fractals and Multifractals in the Geosciences details the application of a wide range of multifractal methods, including many novel ones developed by the author, along with the assessment of uncertainty in sample classification and stability of spatial patterns. This book also provides criteria for selection of the most effective combination of data pre-processing and multifractal modeling to extract desired features or signals in the data. The book specifically aims to introduce, apply, and test novel multifractal models that account directly for changes in relationships between variables, as well as the effects of distance between samples and the source of anomalous metal contents in geoscience samples. Linked to this will be assessment of the effects of different pre-processing of data prior to application of the models and quantification/model uncertainty in geochemical anomaly maps, associated with sample classification and spatial interpolation. Gaussian simulations such as Sequential Gaussian Simulation and Monte Carlo Simulation will be applied to the new multifractal models developed and a suite of existing models, including (simulated) concentration-area, spectrum-area, singularity and other models. Fractals and Multifractals in the Geosciences will be invaluable for mathematical geoscientists, geostatisticians, exploration, applied, urban and environmental geochemists, computational geoscientists, data scientists, and GIS professionals who need to better understand fractal geometry, along with its theory and applications in geochemical anomaly classification to generate maps that are helpful for decision-making for follow-up sampling and explorations. - Provides a comprehensive overview of the use of fractal and multifractal modeling methods, with a detailed assessment of uncertainty quantification in samples and classified models - Specifically includes novel multifractal models, as well as uncertainty quantification and decision-making methods for use in geosciences and especially geochemistry - Includes case studies showing the application of the fractal and multifractal methods detailed in the book
Fractals
Author: Behzad Ghanbarian
Publisher: CRC Press
ISBN: 1351648306
Category : Mathematics
Languages : en
Pages : 289
Book Description
This book provides theoretical concepts and applications of fractals and multifractals to a broad range of audiences from various scientific communities, such as petroleum, chemical, civil and environmental engineering, atmospheric research, and hydrology. In the first chapter, we introduce fractals and multifractals from physics and math viewpoints. We then discuss theory and practical applications in detail. In what follows, in chapter 2, fragmentation process is modeled using fractals. Fragmentation is the breaking of aggregates into smaller pieces or fragments, a typical phenomenon in nature. In chapter 3, the advantages and disadvantages of two- and three-phase fractal models are discussed in detail. These two kinds of approach have been widely applied in the literature to model different characteristics of natural phenomena. In chapter 4, two- and three-phase fractal techniques are used to develop capillary pressure curve models, which characterize pore-size distribution of porous media. Percolation theory provides a theoretical framework to model flow and transport in disordered networks and systems. Therefore, following chapter 4, in chapter 5 the fractal basis of percolation theory and its applications in surface and subsurface hydrology are discussed. In chapter 6, fracture networks are shown to be modeled using fractal approaches. Chapter 7 provides different applications of fractals and multifractals to petrophysics and relevant area in petroleum engineering. In chapter 8, we introduce the practical advantages of fractals and multifractals in geostatistics at large scales, which have broad applications in stochastic hydrology and hydrogeology. Multifractals have been also widely applied to model atmospheric characteristics, such as precipitation, temperature, and cloud shape. In chapter 9, these kinds of properties are addressed using multifractals. At watershed scales, river networks have been shown to follow fractal behavior. Therefore, the applications of fractals are addressed in chapter 10. Time series analysis has been under investigations for several decades in physics, hydrology, atmospheric research, civil engineering, and water resources. In chapter 11, we therefore, provide fractal, multifractal, multifractal detrended fluctuation analyses, which can be used to study temporal characterization of a phenomenon, such as flow discharge at a specific location of a river. Chapter 12 addresses signals and again time series using a novel fractal Fourier analysis. In chapter 13, we discuss constructal theory, which has a perspective opposite to fractal theories, and is based on optimizationof diffusive exchange. In the case of river drainages, for example, the constructal approach begins at the divide and generates headwater streams first, rather than starting from the fundamental drainage pattern.
Publisher: CRC Press
ISBN: 1351648306
Category : Mathematics
Languages : en
Pages : 289
Book Description
This book provides theoretical concepts and applications of fractals and multifractals to a broad range of audiences from various scientific communities, such as petroleum, chemical, civil and environmental engineering, atmospheric research, and hydrology. In the first chapter, we introduce fractals and multifractals from physics and math viewpoints. We then discuss theory and practical applications in detail. In what follows, in chapter 2, fragmentation process is modeled using fractals. Fragmentation is the breaking of aggregates into smaller pieces or fragments, a typical phenomenon in nature. In chapter 3, the advantages and disadvantages of two- and three-phase fractal models are discussed in detail. These two kinds of approach have been widely applied in the literature to model different characteristics of natural phenomena. In chapter 4, two- and three-phase fractal techniques are used to develop capillary pressure curve models, which characterize pore-size distribution of porous media. Percolation theory provides a theoretical framework to model flow and transport in disordered networks and systems. Therefore, following chapter 4, in chapter 5 the fractal basis of percolation theory and its applications in surface and subsurface hydrology are discussed. In chapter 6, fracture networks are shown to be modeled using fractal approaches. Chapter 7 provides different applications of fractals and multifractals to petrophysics and relevant area in petroleum engineering. In chapter 8, we introduce the practical advantages of fractals and multifractals in geostatistics at large scales, which have broad applications in stochastic hydrology and hydrogeology. Multifractals have been also widely applied to model atmospheric characteristics, such as precipitation, temperature, and cloud shape. In chapter 9, these kinds of properties are addressed using multifractals. At watershed scales, river networks have been shown to follow fractal behavior. Therefore, the applications of fractals are addressed in chapter 10. Time series analysis has been under investigations for several decades in physics, hydrology, atmospheric research, civil engineering, and water resources. In chapter 11, we therefore, provide fractal, multifractal, multifractal detrended fluctuation analyses, which can be used to study temporal characterization of a phenomenon, such as flow discharge at a specific location of a river. Chapter 12 addresses signals and again time series using a novel fractal Fourier analysis. In chapter 13, we discuss constructal theory, which has a perspective opposite to fractal theories, and is based on optimizationof diffusive exchange. In the case of river drainages, for example, the constructal approach begins at the divide and generates headwater streams first, rather than starting from the fundamental drainage pattern.
Wavelets and Fractals in Earth System Sciences
Author: E. Chandrasekhar
Publisher: Taylor & Francis
ISBN: 1466553596
Category : Science
Languages : en
Pages : 308
Book Description
The subject of wavelet analysis and fractal analysis is fast developing and has drawn a great deal of attention in varied disciplines of science and engineering. Over the past couple of decades, wavelets, multiresolution, and multifractal analyses have been formalized into a thorough mathematical framework and have found a variety of applications with significant impact in several branches of earth system sciences. Wavelets and Fractals in Earth System Sciences highlights the role of advanced data processing techniques in present-day research in various fields of earth system sciences. The book consists of ten chapters, providing a well-balanced blend of information about the role of wavelets, fractals, and multifractal analyses with the latest examples of their application in various research fields. By combining basics with advanced material, this book introduces concepts as needed and serves as an excellent introductory material and also as an advanced reference text for students and researchers.
Publisher: Taylor & Francis
ISBN: 1466553596
Category : Science
Languages : en
Pages : 308
Book Description
The subject of wavelet analysis and fractal analysis is fast developing and has drawn a great deal of attention in varied disciplines of science and engineering. Over the past couple of decades, wavelets, multiresolution, and multifractal analyses have been formalized into a thorough mathematical framework and have found a variety of applications with significant impact in several branches of earth system sciences. Wavelets and Fractals in Earth System Sciences highlights the role of advanced data processing techniques in present-day research in various fields of earth system sciences. The book consists of ten chapters, providing a well-balanced blend of information about the role of wavelets, fractals, and multifractal analyses with the latest examples of their application in various research fields. By combining basics with advanced material, this book introduces concepts as needed and serves as an excellent introductory material and also as an advanced reference text for students and researchers.
Geoscience After IT
Author: T.V. Loudon
Publisher: Elsevier
ISBN: 0080532519
Category : Science
Languages : en
Pages : 159
Book Description
Most geoscientists are aware of recent IT developments, but cannot spend time on obscure technicalities. Few have considered their implications for the science as a whole. Yet the information industry is moving fast: electronic delivery of hyperlinked multimedia; standards to support interdisciplinary and geographic integration; new models to represent and visualize our concepts, and control and manage our activities; plummeting costs that force the pace. To stay on course, the scientist needs a broad appreciation of the complex and profound interactions of geoscience and IT, not previously reviewed in a single work.The book brings together ideas from many sources, some probably unfamiliar, that bear on the geoscience information system. It encourages readers to give thought to areas that, for various reasons, they have taken for granted, and to take a view on forces affecting geoscience, the consequences for themselves and their organisations, and the need to reconsider, adapt and rebuild.Practicing geoscientists with a general interest in how IT will affect their work and influence future directions of the science; geoscientists familiar with IT applications in their own specialist field who need a broader perspective; and students or educators specializing in IT applications in geoscience who require a top-down overview of their subject will find this title valuable. The IT background from this book should help geoscientists build a strategy for the new century.
Publisher: Elsevier
ISBN: 0080532519
Category : Science
Languages : en
Pages : 159
Book Description
Most geoscientists are aware of recent IT developments, but cannot spend time on obscure technicalities. Few have considered their implications for the science as a whole. Yet the information industry is moving fast: electronic delivery of hyperlinked multimedia; standards to support interdisciplinary and geographic integration; new models to represent and visualize our concepts, and control and manage our activities; plummeting costs that force the pace. To stay on course, the scientist needs a broad appreciation of the complex and profound interactions of geoscience and IT, not previously reviewed in a single work.The book brings together ideas from many sources, some probably unfamiliar, that bear on the geoscience information system. It encourages readers to give thought to areas that, for various reasons, they have taken for granted, and to take a view on forces affecting geoscience, the consequences for themselves and their organisations, and the need to reconsider, adapt and rebuild.Practicing geoscientists with a general interest in how IT will affect their work and influence future directions of the science; geoscientists familiar with IT applications in their own specialist field who need a broader perspective; and students or educators specializing in IT applications in geoscience who require a top-down overview of their subject will find this title valuable. The IT background from this book should help geoscientists build a strategy for the new century.
Dictionary of Mathematical Geosciences
Author: Richard J. Howarth
Publisher: Springer
ISBN: 3319573152
Category : Science
Languages : en
Pages : 892
Book Description
This dictionary includes a number of mathematical, statistical and computing terms and their definitions to assist geoscientists and provide guidance on the methods and terminology encountered in the literature. Each technical term used in the explanations can be found in the dictionary which also includes explanations of basics, such as trigonometric functions and logarithms. There are also citations from the relevant literature to show the term’s first use in mathematics, statistics, etc. and its subsequent usage in geosciences.
Publisher: Springer
ISBN: 3319573152
Category : Science
Languages : en
Pages : 892
Book Description
This dictionary includes a number of mathematical, statistical and computing terms and their definitions to assist geoscientists and provide guidance on the methods and terminology encountered in the literature. Each technical term used in the explanations can be found in the dictionary which also includes explanations of basics, such as trigonometric functions and logarithms. There are also citations from the relevant literature to show the term’s first use in mathematics, statistics, etc. and its subsequent usage in geosciences.
Fractals and Multifractals in Ecology and Aquatic Science
Author: Laurent Seuront
Publisher: CRC Press
ISBN: 1420004247
Category : Mathematics
Languages : en
Pages : 366
Book Description
Ecologists sometimes have a less-than-rigorous background in quantitative methods, yet research within this broad field is becoming increasingly mathematical. Written in a step-by-step fashion, Fractals and Multifractals in Ecology and Aquatic Science provides scientists with a basic understanding of fractals and multifractals and the techniques fo
Publisher: CRC Press
ISBN: 1420004247
Category : Mathematics
Languages : en
Pages : 366
Book Description
Ecologists sometimes have a less-than-rigorous background in quantitative methods, yet research within this broad field is becoming increasingly mathematical. Written in a step-by-step fashion, Fractals and Multifractals in Ecology and Aquatic Science provides scientists with a basic understanding of fractals and multifractals and the techniques fo
Encyclopedia of Mathematical Geosciences
Author: B. S. Daya Sagar
Publisher: Springer Nature
ISBN: 3030850404
Category : Science
Languages : en
Pages : 1744
Book Description
The Encyclopedia of Mathematical Geosciences is a complete and authoritative reference work. It provides concise explanation on each term that is related to Mathematical Geosciences. Over 300 international scientists, each expert in their specialties, have written around 350 separate articles on different topics of mathematical geosciences including contributions on Artificial Intelligence, Big Data, Compositional Data Analysis, Geomathematics, Geostatistics, Geographical Information Science, Mathematical Morphology, Mathematical Petrology, Multifractals, Multiple Point Statistics, Spatial Data Science, Spatial Statistics, and Stochastic Process Modeling. Each topic incorporates cross-referencing to related articles, and also has its own reference list to lead the reader to essential articles within the published literature. The entries are arranged alphabetically, for easy access, and the subject and author indices are comprehensive and extensive.
Publisher: Springer Nature
ISBN: 3030850404
Category : Science
Languages : en
Pages : 1744
Book Description
The Encyclopedia of Mathematical Geosciences is a complete and authoritative reference work. It provides concise explanation on each term that is related to Mathematical Geosciences. Over 300 international scientists, each expert in their specialties, have written around 350 separate articles on different topics of mathematical geosciences including contributions on Artificial Intelligence, Big Data, Compositional Data Analysis, Geomathematics, Geostatistics, Geographical Information Science, Mathematical Morphology, Mathematical Petrology, Multifractals, Multiple Point Statistics, Spatial Data Science, Spatial Statistics, and Stochastic Process Modeling. Each topic incorporates cross-referencing to related articles, and also has its own reference list to lead the reader to essential articles within the published literature. The entries are arranged alphabetically, for easy access, and the subject and author indices are comprehensive and extensive.
Fractals
Author: Behzad Ghanbarian
Publisher: CRC Press
ISBN: 1498748724
Category : Mathematics
Languages : en
Pages : 364
Book Description
This book provides theoretical concepts and applications of fractals and multifractals to a broad range of audiences from various scientific communities, such as petroleum, chemical, civil and environmental engineering, atmospheric research, and hydrology. In the first chapter, we introduce fractals and multifractals from physics and math viewpoints. We then discuss theory and practical applications in detail. In what follows, in chapter 2, fragmentation process is modeled using fractals. Fragmentation is the breaking of aggregates into smaller pieces or fragments, a typical phenomenon in nature. In chapter 3, the advantages and disadvantages of two- and three-phase fractal models are discussed in detail. These two kinds of approach have been widely applied in the literature to model different characteristics of natural phenomena. In chapter 4, two- and three-phase fractal techniques are used to develop capillary pressure curve models, which characterize pore-size distribution of porous media. Percolation theory provides a theoretical framework to model flow and transport in disordered networks and systems. Therefore, following chapter 4, in chapter 5 the fractal basis of percolation theory and its applications in surface and subsurface hydrology are discussed. In chapter 6, fracture networks are shown to be modeled using fractal approaches. Chapter 7 provides different applications of fractals and multifractals to petrophysics and relevant area in petroleum engineering. In chapter 8, we introduce the practical advantages of fractals and multifractals in geostatistics at large scales, which have broad applications in stochastic hydrology and hydrogeology. Multifractals have been also widely applied to model atmospheric characteristics, such as precipitation, temperature, and cloud shape. In chapter 9, these kinds of properties are addressed using multifractals. At watershed scales, river networks have been shown to follow fractal behavior. Therefore, the applications of fractals are addressed in chapter 10. Time series analysis has been under investigations for several decades in physics, hydrology, atmospheric research, civil engineering, and water resources. In chapter 11, we therefore, provide fractal, multifractal, multifractal detrended fluctuation analyses, which can be used to study temporal characterization of a phenomenon, such as flow discharge at a specific location of a river. Chapter 12 addresses signals and again time series using a novel fractal Fourier analysis. In chapter 13, we discuss constructal theory, which has a perspective opposite to fractal theories, and is based on optimizationof diffusive exchange. In the case of river drainages, for example, the constructal approach begins at the divide and generates headwater streams first, rather than starting from the fundamental drainage pattern.
Publisher: CRC Press
ISBN: 1498748724
Category : Mathematics
Languages : en
Pages : 364
Book Description
This book provides theoretical concepts and applications of fractals and multifractals to a broad range of audiences from various scientific communities, such as petroleum, chemical, civil and environmental engineering, atmospheric research, and hydrology. In the first chapter, we introduce fractals and multifractals from physics and math viewpoints. We then discuss theory and practical applications in detail. In what follows, in chapter 2, fragmentation process is modeled using fractals. Fragmentation is the breaking of aggregates into smaller pieces or fragments, a typical phenomenon in nature. In chapter 3, the advantages and disadvantages of two- and three-phase fractal models are discussed in detail. These two kinds of approach have been widely applied in the literature to model different characteristics of natural phenomena. In chapter 4, two- and three-phase fractal techniques are used to develop capillary pressure curve models, which characterize pore-size distribution of porous media. Percolation theory provides a theoretical framework to model flow and transport in disordered networks and systems. Therefore, following chapter 4, in chapter 5 the fractal basis of percolation theory and its applications in surface and subsurface hydrology are discussed. In chapter 6, fracture networks are shown to be modeled using fractal approaches. Chapter 7 provides different applications of fractals and multifractals to petrophysics and relevant area in petroleum engineering. In chapter 8, we introduce the practical advantages of fractals and multifractals in geostatistics at large scales, which have broad applications in stochastic hydrology and hydrogeology. Multifractals have been also widely applied to model atmospheric characteristics, such as precipitation, temperature, and cloud shape. In chapter 9, these kinds of properties are addressed using multifractals. At watershed scales, river networks have been shown to follow fractal behavior. Therefore, the applications of fractals are addressed in chapter 10. Time series analysis has been under investigations for several decades in physics, hydrology, atmospheric research, civil engineering, and water resources. In chapter 11, we therefore, provide fractal, multifractal, multifractal detrended fluctuation analyses, which can be used to study temporal characterization of a phenomenon, such as flow discharge at a specific location of a river. Chapter 12 addresses signals and again time series using a novel fractal Fourier analysis. In chapter 13, we discuss constructal theory, which has a perspective opposite to fractal theories, and is based on optimizationof diffusive exchange. In the case of river drainages, for example, the constructal approach begins at the divide and generates headwater streams first, rather than starting from the fundamental drainage pattern.
Geologic Modeling and Simulation
Author: Daniel F. Merriam
Publisher: Springer Science & Business Media
ISBN: 1461513596
Category : Science
Languages : en
Pages : 362
Book Description
Modeling and simulation were introduced to the earth sciences about four decades ago. Modeling has proven its worth and now it is an accepted procedure for analyzing and solving geological problems. The papers in this collection are focused on modeling sediment deposition and sedimentary sequences and have a decidedly practical flavor. Some of the leading simulation packages, such as CORRELATOR, SEDFLUX, SEDpak, SEDSIM, STRATA, and STRATSIM are applied to problems in hydrocarbon exploration, oil production, groundwater development, coal-bed appraisal, geothermics, and environmental diagnosis. All of these subjects fall under the broad heading of sedimentary basin analysis. The fifteen papers in this volume are written by internationally recognized experts from academia and industry. The contributions represent the status of geologic modeling and simulation at the start of the 21st century, and will give the reader an insight into current research problems and their possible solutions.
Publisher: Springer Science & Business Media
ISBN: 1461513596
Category : Science
Languages : en
Pages : 362
Book Description
Modeling and simulation were introduced to the earth sciences about four decades ago. Modeling has proven its worth and now it is an accepted procedure for analyzing and solving geological problems. The papers in this collection are focused on modeling sediment deposition and sedimentary sequences and have a decidedly practical flavor. Some of the leading simulation packages, such as CORRELATOR, SEDFLUX, SEDpak, SEDSIM, STRATA, and STRATSIM are applied to problems in hydrocarbon exploration, oil production, groundwater development, coal-bed appraisal, geothermics, and environmental diagnosis. All of these subjects fall under the broad heading of sedimentary basin analysis. The fifteen papers in this volume are written by internationally recognized experts from academia and industry. The contributions represent the status of geologic modeling and simulation at the start of the 21st century, and will give the reader an insight into current research problems and their possible solutions.
Fractal and Multifractal Facets in the Structure and Dynamics of Physiological Systems and Applications to Homeostatic Control, Disease Diagnosis and Integrated Cyber-Physical Platforms
Author: Paul Bogdan
Publisher: Frontiers Media SA
ISBN: 2889635317
Category :
Languages : en
Pages : 180
Book Description
Widespread chronic diseases (e.g., heart diseases, diabetes and its complications, stroke, cancer, brain diseases) constitute a significant cause of rising healthcare costs and pose a significant burden on quality-of-life for many individuals. Despite the increased need for smart healthcare sensing systems that monitor / measure patients’ body balance, there is no coherent theory that facilitates the modeling of human physiological processes and the design and optimization of future healthcare cyber-physical systems (HCPS). The HCPS are expected to mine the patient’s physiological state based on available continuous sensing, quantify risk indices corresponding to the onset of abnormality, signal the need for critical medical intervention in real-time by communicating patient’s medical information via a network from individual to hospital, and most importantly control (actuate) vital health signals (e.g., cardiac pacing, insulin level, blood pressure) within personalized homeostasis. To prevent health complications, maintain good health and/or avoid fatal conditions calls for a cross-disciplinary approach to HCPS design where recent statistical-physics inspired discoveries done by collaborations between physicists and physicians are shared and enriched by applied mathematicians, control theorists and bioengineers. This critical and urgent multi-disciplinary approach has to unify the current state of knowledge and address the following fundamental challenges: One fundamental challenge is represented by the need to mine and understand the complexity of the structure and dynamics of the physiological systems in healthy homeostasis and associated with a disease (such as diabetes). Along the same lines, we need rigorous mathematical techniques for identifying the interactions between integrated physiologic systems and understanding their role within the overall networking architecture of healthy dynamics. Another fundamental challenge calls for a deeper understanding of stochastic feedback and variability in biological systems and physiological processes, in particular, and for deciphering their implications not only on how to mathematically characterize homeostasis, but also on defining new control strategies that are accounting for intra- and inter-patient specificity – a truly mathematical approach to personalized medicine. Numerous recent studies have demonstrated that heart rate variability, blood glucose, neural signals and other interdependent physiological processes demonstrate fractal and non-stationary characteristics. Exploiting statistical physics concepts, numerous recent research studies demonstrated that healthy human physiological processes exhibit complex critical phenomena with deep implications for how homeostasis should be defined and how control strategies should be developed when prolonged abnormal deviations are observed. In addition, several efforts have tried to connect these fractal characteristics with new optimal control strategies that implemented in medical devices such as pacemakers and artificial pancreas could improve the efficiency of medical therapies and the quality-of-life of patients but neglecting the overall networking architecture of human physiology. Consequently, rigorously analyzing the complexity and dynamics of physiological processes (e.g., blood glucose and its associated implications and interdependencies with other physiological processes) represents a fundamental step towards providing a quantifiable (mathematical) definition of homeostasis in the context of critical phenomena, understanding the onset of chronic diseases, predicting deviations from healthy homeostasis and developing new more efficient medical therapies that carefully account for the physiological complexity, intra- and inter-patient variability, rather than ignoring it. This Research Topic aims to open a synergetic and timely effort between physicians, physicists, applied mathematicians, signal processing, bioengineering and biomedical experts to organize the state of knowledge in mining the complexity of physiological systems and their implications for constructing more accurate mathematical models and designing QoL-aware control strategies implemented in the new generation of HCPS devices. By bringing together multi-disciplinary researchers seeking to understand the many aspects of human physiology and its complexity, we aim at enabling a paradigm shift in designing future medical devices that translates mathematical characteristics in predictable mathematical models quantifying not only the degree of homeostasis, but also providing fundamentally new control strategies within the personalized medicine era.
Publisher: Frontiers Media SA
ISBN: 2889635317
Category :
Languages : en
Pages : 180
Book Description
Widespread chronic diseases (e.g., heart diseases, diabetes and its complications, stroke, cancer, brain diseases) constitute a significant cause of rising healthcare costs and pose a significant burden on quality-of-life for many individuals. Despite the increased need for smart healthcare sensing systems that monitor / measure patients’ body balance, there is no coherent theory that facilitates the modeling of human physiological processes and the design and optimization of future healthcare cyber-physical systems (HCPS). The HCPS are expected to mine the patient’s physiological state based on available continuous sensing, quantify risk indices corresponding to the onset of abnormality, signal the need for critical medical intervention in real-time by communicating patient’s medical information via a network from individual to hospital, and most importantly control (actuate) vital health signals (e.g., cardiac pacing, insulin level, blood pressure) within personalized homeostasis. To prevent health complications, maintain good health and/or avoid fatal conditions calls for a cross-disciplinary approach to HCPS design where recent statistical-physics inspired discoveries done by collaborations between physicists and physicians are shared and enriched by applied mathematicians, control theorists and bioengineers. This critical and urgent multi-disciplinary approach has to unify the current state of knowledge and address the following fundamental challenges: One fundamental challenge is represented by the need to mine and understand the complexity of the structure and dynamics of the physiological systems in healthy homeostasis and associated with a disease (such as diabetes). Along the same lines, we need rigorous mathematical techniques for identifying the interactions between integrated physiologic systems and understanding their role within the overall networking architecture of healthy dynamics. Another fundamental challenge calls for a deeper understanding of stochastic feedback and variability in biological systems and physiological processes, in particular, and for deciphering their implications not only on how to mathematically characterize homeostasis, but also on defining new control strategies that are accounting for intra- and inter-patient specificity – a truly mathematical approach to personalized medicine. Numerous recent studies have demonstrated that heart rate variability, blood glucose, neural signals and other interdependent physiological processes demonstrate fractal and non-stationary characteristics. Exploiting statistical physics concepts, numerous recent research studies demonstrated that healthy human physiological processes exhibit complex critical phenomena with deep implications for how homeostasis should be defined and how control strategies should be developed when prolonged abnormal deviations are observed. In addition, several efforts have tried to connect these fractal characteristics with new optimal control strategies that implemented in medical devices such as pacemakers and artificial pancreas could improve the efficiency of medical therapies and the quality-of-life of patients but neglecting the overall networking architecture of human physiology. Consequently, rigorously analyzing the complexity and dynamics of physiological processes (e.g., blood glucose and its associated implications and interdependencies with other physiological processes) represents a fundamental step towards providing a quantifiable (mathematical) definition of homeostasis in the context of critical phenomena, understanding the onset of chronic diseases, predicting deviations from healthy homeostasis and developing new more efficient medical therapies that carefully account for the physiological complexity, intra- and inter-patient variability, rather than ignoring it. This Research Topic aims to open a synergetic and timely effort between physicians, physicists, applied mathematicians, signal processing, bioengineering and biomedical experts to organize the state of knowledge in mining the complexity of physiological systems and their implications for constructing more accurate mathematical models and designing QoL-aware control strategies implemented in the new generation of HCPS devices. By bringing together multi-disciplinary researchers seeking to understand the many aspects of human physiology and its complexity, we aim at enabling a paradigm shift in designing future medical devices that translates mathematical characteristics in predictable mathematical models quantifying not only the degree of homeostasis, but also providing fundamentally new control strategies within the personalized medicine era.