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Author: Vincent T. Andriole
Publisher: Academic Press
ISBN: 1483216039
Category : Medical
Languages : en
Pages : 275
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Book Description
The Quinolones covers reviews on the history, chemistry and mechanism of action, in vitro properties, pharmacokinetics, clinical overview, toxicity, adverse effects and drug interactions, and future prospects of the 4-quinolones. The book discusses the microbiology of quinolones, particularly with consideration of the development of resistance, pharmacology, toxicology, and clinical uses. Chemists, microbiologists, pharmacologists and clinicians will find the book useful.
Author: Vincent T. Andriole
Publisher: Academic Press
ISBN: 1483216039
Category : Medical
Languages : en
Pages : 275
Get Book Here
Book Description
The Quinolones covers reviews on the history, chemistry and mechanism of action, in vitro properties, pharmacokinetics, clinical overview, toxicity, adverse effects and drug interactions, and future prospects of the 4-quinolones. The book discusses the microbiology of quinolones, particularly with consideration of the development of resistance, pharmacology, toxicology, and clinical uses. Chemists, microbiologists, pharmacologists and clinicians will find the book useful.
Author: Stefan Pieper
Publisher: Springer Nature
ISBN: 3030741737
Category : Medical
Languages : en
Pages : 76
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Book Description
In this book, Stefan Pieper supports doctors and therapists in easily diagnosing FQAD and in better and more adequately dealing with FQAD patients. Fluoroquinolones, as one of the most common and effective groups of antibiotics, are known to have a distinct spectrum of side effects. These adverse effects are rare in percentage terms, but frequent in absolute numbers due to the enormous quantities of prescriptions. Because they are usually quite severe and wide-ranging, they tend to run like a syndrome and have been classified by the FDA as a separate condition, the FQAD, because of their frequency, severity and risk of disability. This book presents for the first time a comprehensive description and classification of the clinical picture and a proposal for a clinical diagnostic tool based on diagnostic criteria.
Author: Allan R. Ronald
Publisher: Birkhäuser
ISBN: 3034881037
Category : Medical
Languages : en
Pages : 263
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Book Description
The quinolones are making a significant contribution to patient care and have added a new dimension to antibacterial therapy. During the last decade, they became important agents for treating hospital-acquired infections. This volume covers their mechanisms of action, resistance mechanisms and epidemiology, pharmacokinetics, safety and clinical applications. Their effectiveness for respiratory, urinary, sexually transmitted, skin, soft tissue, bone and joint infections, infections of the eyes, ears, nose and throat, and less common infections such as mycobacterial, Brucella and others are reviewed. Also described is their use in pediatric, oncology and immunocompromised patients. The quinolone story continues to be intriguing with exciting future implications.This monograph is an important comprehensive review and update for researchers and clinicians in pharmacology, clinical medicine, molecular and cell biology, epidemiology and the pharmaceutical industry.
Author:
Publisher: Academic Press
ISBN: 0128173173
Category : Medical
Languages : en
Pages : 290
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Book Description
Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. - Includes the authority and expertise of leading contributors in pharmacology - Presents the latest release in the Advances in Pharmacology series
Author: Neil Kaplowitz
Publisher: CRC Press
ISBN: 0203909127
Category : Medical
Languages : en
Pages : 790
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Book Description
Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.
Author: Hyman J. Zimmerman
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781719520
Category : Medical
Languages : en
Pages : 850
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Book Description
Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.
Author: Nightingale
Publisher: CRC Press
ISBN: 082474182X
Category : Medical
Languages : en
Pages : 427
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Book Description
This up-to-the-minute reference explores the pharmacodynamics of antimicrobials as well as the absorption, distribution, metabolism, and elimination of the major classes of antimicrobials-covering new agents such as ketolide antibiotics and highlighting the pharmacodynamic relationship between drug concentration and antimicrobial activity, as well as the relationship of pharmacodynamics to bacterial resistance. Contains specific examples and practical applications for the design of effective dosing regimens! Written by recognized experts in the field, Antimicrobial Pharmacodynamics in Theory and Clinical Practice describes the pharmacodynamic properties of all major classes of antibiotics parameters for microbiological activity of antimicrobial agents such as minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) serum/tissue protein binding and penetration rates differences between in vivo and in vitro postantibiotic effects (PAE) and more! With nearly 1000 references, tables, drawings, and illustrations, Antimicrobial Pharmacodynamics in Theory and Clinical Practice is a state-of-the-art reference for infectious disease specialists, pulmonologists, pharmacists, pharmacologists, microbiologists, biological chemists, epidemiologists, internists, and students in these disciplines.
Author: Victor Lorian
Publisher: Lippincott Williams & Wilkins
ISBN: 9780781749831
Category : Medical
Languages : en
Pages : 924
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Book Description
Implement the most current science and practice in antimicrobial research. Now, find the newest approaches for evaluating the activity, mechanisms of action, and bacterial resistance to antibiotics with this completely updated, landmark reference. Turn to this comprehensive reference for groundbreaking evidence on the molecular link between chemical disinfectants, sterilants, and antibiotics. On the latest methods for detecting antibacterial resistance genes in the clinical laboratory, and antivirogram use to select the most active antiviral components against your patient's HIV.
Author: Thomas Yorio
Publisher: Academic Press
ISBN: 0080556779
Category : Science
Languages : en
Pages : 537
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Book Description
Ocular Therapeutics: Eye on New Discovery focuses on emerging areas in ocular research, from new approaches to dry eye to gene therapy in the management of retinal diseases. This comprehensive book features more than 25 chapters of information that will be vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics. It is the intent of this book to provide not only information on current approaches to treatment, but also in giving the reader a greater understanding as to what may become available for treating a number of important eye diseases. Each chapter features some new aspect of treatment that holds great promise for the future. The approach has been to concentrate on those areas of ocular diseases that are more prevalent. It also features new insight for drug delivery and for managing devasting diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States. This book will serve as an important resource as it contains a number of relevant references highlighted for their importance to the field. New investigators will be able to obtain an historical perspective for each of the topics and to develop an understanding of the new research directions that are underway. Ocular Therapeutics: Eye on New Discovery is more than a reference book, as it also provides an important glimpse into the near future.* Contains information that is vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics.* Provides not only information on current approaches to treatment, but also gives the reader a greater understanding as to what may become available for treating a number of important eye diseases.* Historical perspective for each of the topics as well as an important glimpse into the near future to develop an understanding of the new research directions underway.* New insight for drug delivery and for managing devastating diseases, such as macula edema and glaucoma, two of the leading causes of blindness in the United States
Author: Melanie Ludwinski
Publisher: M. Ludwinski Verlag
ISBN: 3961126364
Category : Medical
Languages : en
Pages : 62
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Book Description
Updated edition with further insights and honest reports on Gerald's enormous progress in health. My husband's name is Gerald and he is a collateral damage victim of fluoroquinolone antibiotics, in short, he is floxed! Until a few weeks ago, we had neither heard of the term 'floxed' nor did we know what it means, as in to be affected by severe side effects after taking the aforementioned antibiotics and to therefore become very ill. An almost unbelievable total of 39 side effects affected Gerald or are still affecting him and based on his experiences and subsequent research into his condition, this book is intended to offer both: guidance and for similarly affected people, their relatives and friends. And as a word of caution: please take these antibiotics only after very careful consideration. A note like 'please tell your Doctor or Pharmacist if you suffer from any listed side effects...' is always be included in any medication packages. Unfortunately, though, such references are apparently not taken seriously by the medical profession, nor does any advice or assistance from this side seem to exist as there is no treatment option available. Gerald, therefore, has no other option than to help himself and to share whatever information we have gleaned in this regard with others who may hopefully also benefit thereby. I'm simply going to describe Geralds experiences he went through and explain his different methods (nutritional supplements, medication, and alternatives) he has tried, in order to become human once again. However, Gerald is not a doctor, so this book cannot and must not replace a doctor's consultation, nor should it replace a professional medical diagnosis!
