Author: Alain Tressaud
Publisher: Elsevier
ISBN: 0080558119
Category : Medical
Languages : en
Pages : 821
Book Description
Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms.Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized. - New approach of topics involving chemistry, biology and medicinal techniques - Transdisciplinar papers on fluoride products - Importance of fluoride products in health - Updated data on specific topics
Fluorine and Health
Author: Alain Tressaud
Publisher: Elsevier
ISBN: 0080558119
Category : Medical
Languages : en
Pages : 821
Book Description
Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms.Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized. - New approach of topics involving chemistry, biology and medicinal techniques - Transdisciplinar papers on fluoride products - Importance of fluoride products in health - Updated data on specific topics
Publisher: Elsevier
ISBN: 0080558119
Category : Medical
Languages : en
Pages : 821
Book Description
Fluorine and Health presents a critical multidisciplinary overview on the contribution of fluorinated compounds to resolve the important global issue of medicinal monitoring and health care. The involved subjects are organized in three thematic parts devoted to Molecular Imaging, Biomedical Materials and Pharmaceuticals. Initially the key-position of partially fluorinated low molecular weight compounds labelled either with the natural 19F-isotope for Magnetic Resonance Imaging (MRI) or labelled with the radioactive [18F]-isotope for Positron Emission Tomography (PET) is highlighted. Both non-invasive methods belong to the most challenging in vivo imaging techniques in oncology, neurology and in cardiology for the diagnosis of diseases having the highest mortality in the industrialized countries. The manifold facets of fluorinated biomaterials range from inorganic ceramics to perfluorinated organic molecules. Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms.Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds. The chapters will illustrate how the presence of fluorine atoms alters properties of bioactive compounds at various biochemical steps, and possibly facilitate its emergence as pharmaceuticals. Finally the synthetic potential of a fluorinase, the first C-F bond forming enzyme, is summarized. - New approach of topics involving chemistry, biology and medicinal techniques - Transdisciplinar papers on fluoride products - Importance of fluoride products in health - Updated data on specific topics
Fluorine and Health
Author: Alain Tressaud
Publisher: Elsevier Science Limited
ISBN: 9780444530868
Category : Science
Languages : en
Pages : 792
Book Description
Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms. Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds.-
Publisher: Elsevier Science Limited
ISBN: 9780444530868
Category : Science
Languages : en
Pages : 792
Book Description
Liquid perfluorocarbons are suitable for oxygen transport and as potential respiratory gas carriers, while fluorinated polymers are connected to the pathology of blood vessels. Another important issue concerns the application of highly fluorinated liquids in ophthalmology. Moreover, fluorine is an essential trace element in bone mineral, dentine and tooth enamel and is applied for the prophylaxis and treatment of dental caries. The various origins of human exposure to fluoride species is detailed to promote a better understanding of the effect of fluoride species on living organisms. Medicinally relevant fluorinated molecules and their interactions with native proteins are the main focus of the third part. New molecules fluorinated in strategic position are crucial for the development of pharmaceuticals with desired action and optimal pharmacological profile. Among the hundreds of marketed active drug components there are more than 150 fluorinated compounds.-
Fluoridation Facts
Author: American Dental Association
Publisher: American Dental Association
ISBN: 1684470064
Category : Technology & Engineering
Languages : en
Pages : 233
Book Description
All-in-one resource in for everything related to fluoridated water, from its impact on dental health to its safety and cost-effectiveness. Dispelling common myths that fluoridation is dangerous, this book provides science-backed information based on the most current research in Q&A format. This is the most in-depth and up-to-date educational resource available regarding fluoridated water, from the American Dental Association.
Publisher: American Dental Association
ISBN: 1684470064
Category : Technology & Engineering
Languages : en
Pages : 233
Book Description
All-in-one resource in for everything related to fluoridated water, from its impact on dental health to its safety and cost-effectiveness. Dispelling common myths that fluoridation is dangerous, this book provides science-backed information based on the most current research in Q&A format. This is the most in-depth and up-to-date educational resource available regarding fluoridated water, from the American Dental Association.
The Overlooked Individual: Susceptibility to Dental Caries, Erosive Tooth Wear and Amelogenesis
Author: Alexandre Rezende Vieira
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318069132
Category : Medical
Languages : en
Pages : 165
Book Description
Individual susceptibility to disease (i.e., one’s own genetic background) is one of the three main components classically described in the etiology of dental caries. Hence, genes influence susceptibility to erosive tooth wear, dental development, and response to treatments and interventions. This publication is an up-to-date overview of individual susceptibility to dental caries, erosive tooth wear, and disturbances of dental development from different clinically relevant perspectives. One of the most recognized scientists in this field reports on recent research relating to human genetics – from general summaries to recommendations for daily clinical work and population-level interventions. This book covers all aspects of individual susceptibility to dental caries and erosive tooth wear. Several chapters deal with potential biological mechanisms, with additional ones providing a strong foundation in human genetics, and other chapters touch on efficacy of therapies and alternative concepts. This book is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on dental caries and erosive tooth wear.
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318069132
Category : Medical
Languages : en
Pages : 165
Book Description
Individual susceptibility to disease (i.e., one’s own genetic background) is one of the three main components classically described in the etiology of dental caries. Hence, genes influence susceptibility to erosive tooth wear, dental development, and response to treatments and interventions. This publication is an up-to-date overview of individual susceptibility to dental caries, erosive tooth wear, and disturbances of dental development from different clinically relevant perspectives. One of the most recognized scientists in this field reports on recent research relating to human genetics – from general summaries to recommendations for daily clinical work and population-level interventions. This book covers all aspects of individual susceptibility to dental caries and erosive tooth wear. Several chapters deal with potential biological mechanisms, with additional ones providing a strong foundation in human genetics, and other chapters touch on efficacy of therapies and alternative concepts. This book is particularly recommended to dental medicine students, practitioners, other oral healthcare professionals, and scientists with an interest in translational research on dental caries and erosive tooth wear.
Fluoride in Drinking Water
Author: A.K. Gupta
Publisher: CRC Press
ISBN: 1498756530
Category : Science
Languages : en
Pages : 208
Book Description
Explore the Health Effects of Fluoride PollutionFluoride in Drinking Water: Status, Issues, and Solutions establishes the negative impacts of naturally occurring fluoride on human health and considers the depth and scope of fluoride pollution on an international scale. The book discusses current global water quality and fluoride-related issues and
Publisher: CRC Press
ISBN: 1498756530
Category : Science
Languages : en
Pages : 208
Book Description
Explore the Health Effects of Fluoride PollutionFluoride in Drinking Water: Status, Issues, and Solutions establishes the negative impacts of naturally occurring fluoride on human health and considers the depth and scope of fluoride pollution on an international scale. The book discusses current global water quality and fluoride-related issues and
Fluoride in Drinking-water
Author: John Kirtley Fawell
Publisher: World Health Organization
ISBN: 9241563192
Category : Health & Fitness
Languages : en
Pages : 145
Book Description
Fluoride is known to occur at elevated concentration in a number of parts of the world, where it can be a significant cause of disease. The primary focus of this book is the prevention of adverse health effects from excessive levels of fluoride in drinking water. The book fills the urgent need, identified for updating the WHO Guidelines for Drinking-water Quality, for information on the occurrence of fluoride, its health effects, ways of reducing excess levels, and methods for analysis of fluoride in water. The draft document, produced by a working group of experts convened to consider protection from fluoride and its control, was issued for extensive review and consultation. The resultant book, which incorporates the comments received, was further peer reviewed by experts in developed and developing countries. It is aimed at a wide range of individuals, including health workers and sanitary engineers who may require a broad introduction to the subject with more detailed guidance in some specific areas. Fluoride in Drinking-waterwill be an invaluable reference source for all those concerned with the management of drinking water containing fluoride and the health effects arising from its consumption, including water sector managers and practitioners, as well as health sector staff at policy and implementation levels. It will also be of interest to researchers, students, development workers, and consultants.
Publisher: World Health Organization
ISBN: 9241563192
Category : Health & Fitness
Languages : en
Pages : 145
Book Description
Fluoride is known to occur at elevated concentration in a number of parts of the world, where it can be a significant cause of disease. The primary focus of this book is the prevention of adverse health effects from excessive levels of fluoride in drinking water. The book fills the urgent need, identified for updating the WHO Guidelines for Drinking-water Quality, for information on the occurrence of fluoride, its health effects, ways of reducing excess levels, and methods for analysis of fluoride in water. The draft document, produced by a working group of experts convened to consider protection from fluoride and its control, was issued for extensive review and consultation. The resultant book, which incorporates the comments received, was further peer reviewed by experts in developed and developing countries. It is aimed at a wide range of individuals, including health workers and sanitary engineers who may require a broad introduction to the subject with more detailed guidance in some specific areas. Fluoride in Drinking-waterwill be an invaluable reference source for all those concerned with the management of drinking water containing fluoride and the health effects arising from its consumption, including water sector managers and practitioners, as well as health sector staff at policy and implementation levels. It will also be of interest to researchers, students, development workers, and consultants.
Prevalence and Severity of Dental Fluorosis in the United States, 1999-2004
Author: Eugenio D. Beltrán-Aguilar
Publisher:
ISBN:
Category : Fluorides
Languages : en
Pages : 8
Book Description
"Dental fluorosis refers to changes in the appearance of tooth enamel that are caused by long-term ingestion of fluoride during the time teeth are forming. Studies conducted in the 1930s showed that the severity of tooth decay was lower and dental fluorosis was higher in areas with more fluoride in the drinking water. In response to these findings, community water fluoridation programs were developed to add fluoride to drinking water to reach an optimal level for preventing tooth decay, while limiting the chance of developing dental fluorosis. By the 1980s, studies in selected U.S. communities reported an increase in dental fluorosis, paralleling the expansion of water fluoridation and the increased availability of other sources of ingested fluoride, such as fluoride toothpaste (if swallowed) and fluoride supplements. This report describes the prevalence of dental fluorosis in the United States and changes in the prevalence and severity of dental fluorosis among adolescents between 1986-1987 and 1999-2004. Data from the National Health and Nutrition Examination Survey, 1999-2004 and the 1986-1987 National Survey of Oral Health in U.S. School Children." - p. 1.
Publisher:
ISBN:
Category : Fluorides
Languages : en
Pages : 8
Book Description
"Dental fluorosis refers to changes in the appearance of tooth enamel that are caused by long-term ingestion of fluoride during the time teeth are forming. Studies conducted in the 1930s showed that the severity of tooth decay was lower and dental fluorosis was higher in areas with more fluoride in the drinking water. In response to these findings, community water fluoridation programs were developed to add fluoride to drinking water to reach an optimal level for preventing tooth decay, while limiting the chance of developing dental fluorosis. By the 1980s, studies in selected U.S. communities reported an increase in dental fluorosis, paralleling the expansion of water fluoridation and the increased availability of other sources of ingested fluoride, such as fluoride toothpaste (if swallowed) and fluoride supplements. This report describes the prevalence of dental fluorosis in the United States and changes in the prevalence and severity of dental fluorosis among adolescents between 1986-1987 and 1999-2004. Data from the National Health and Nutrition Examination Survey, 1999-2004 and the 1986-1987 National Survey of Oral Health in U.S. School Children." - p. 1.
Toxicological Profile for Fluorides, Hydrogen Fluoride, and Fluorine
Author:
Publisher:
ISBN:
Category : Fluorides
Languages : en
Pages : 280
Book Description
Publisher:
ISBN:
Category : Fluorides
Languages : en
Pages : 280
Book Description
Fluorides in the Environment
Author: Leonard H. Weinstein
Publisher: CABI
ISBN: 9780851998725
Category : Science
Languages : en
Pages : 320
Book Description
Fluoride pollution is a problem in all industrialized countries. The topic of fluorides in medicine and agriculture, and fluoridation of public water supplies is one that has attracted much controversy. This book aims to review the research findings, and provide a comprehensive reference on the effects of fluorides on plants and animals. It also includes information on conducting field surveys, establishing air quality criteria and standards, and the problems associated with fluoride analysis in air, water, soil and vegetation.
Publisher: CABI
ISBN: 9780851998725
Category : Science
Languages : en
Pages : 320
Book Description
Fluoride pollution is a problem in all industrialized countries. The topic of fluorides in medicine and agriculture, and fluoridation of public water supplies is one that has attracted much controversy. This book aims to review the research findings, and provide a comprehensive reference on the effects of fluorides on plants and animals. It also includes information on conducting field surveys, establishing air quality criteria and standards, and the problems associated with fluoride analysis in air, water, soil and vegetation.
Nutrition and Bone Health
Author: Michael F. Holick
Publisher: Springer
ISBN: 1493920014
Category : Medical
Languages : en
Pages : 737
Book Description
This newly revised edition contains updated versions of all of the topics that were in the first edition and has been substantially expanded with an additional 5 chapters. Each chapter includes information from the most up-to-date research on how nutritional factors can affect bone health, written with an evidence-based focus and complete with comprehensive references for each subject. Nutrition and Bone Health, second edition covers all aspects of nutrition and the skeleton, from the history and fundamentals, to the effects of macronutrients, minerals, vitamins, and supplements, and even covers the effects of lifestyle, the different life stages, and nutrition-related disorders and secondary osteoporosis. New chapters include HIV & AIDs and the skeleton, celiac disease and bone health, and nutrition and bone health in space. Nutrition and Bone Health, second edition is a necessary resource for health care professionals, medical students, graduate students, dietitians, and nutritionists who are interested in how nutrition affects bone health during all stages of life.
Publisher: Springer
ISBN: 1493920014
Category : Medical
Languages : en
Pages : 737
Book Description
This newly revised edition contains updated versions of all of the topics that were in the first edition and has been substantially expanded with an additional 5 chapters. Each chapter includes information from the most up-to-date research on how nutritional factors can affect bone health, written with an evidence-based focus and complete with comprehensive references for each subject. Nutrition and Bone Health, second edition covers all aspects of nutrition and the skeleton, from the history and fundamentals, to the effects of macronutrients, minerals, vitamins, and supplements, and even covers the effects of lifestyle, the different life stages, and nutrition-related disorders and secondary osteoporosis. New chapters include HIV & AIDs and the skeleton, celiac disease and bone health, and nutrition and bone health in space. Nutrition and Bone Health, second edition is a necessary resource for health care professionals, medical students, graduate students, dietitians, and nutritionists who are interested in how nutrition affects bone health during all stages of life.