Fluorescence-Guided Neurosurgery

Fluorescence-Guided Neurosurgery PDF Author: Constantinos G. Hadjipanayis
Publisher: Thieme
ISBN: 1626237158
Category : Medical
Languages : en
Pages : 376

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Book Description
The definitive textbook on state-of-the-art fluorescence-guided neurosurgery Advances in fluorescence-guided surgery (FGS) have resulted in a paradigm shift in neurosurgical approaches to neuro-oncological and cerebrovascular pathologies. Edited by two of the foremost authorities on the topic, Fluorescence-Guided Neurosurgery: Neuro-oncology and Cerebrovascular Applications encompasses the depth and breadth of this groundbreaking, still nascent technology. The book reflects significant contributions made by world renowned neurosurgeons Constantinos Hadjipanayis, Walter Stummer, and esteemed contributors on the growing uses of 5-aminolevulinic acid (5-ALA) and other FGS agents. The European Medicine Agency approved 5-ALA in 2007, heralding the birth of FGS globally. In 2017, the U.S. Food and Drug Administration approved 5-ALA (Gleolan) as an imaging agent to facilitate realtime detection and visualization of malignant tissue during glioma surgery. In the two decades since Dr. Stummer's initial description of 5-ALA FGS in a human patient, major strides have been made in its practical applications, leading to improved resection outcomes. As FGS is increasingly incorporated into neurosurgical practice, it holds promise for future innovations. Generously-illustrated and enhanced with online videos, this textbook is the definitive resource on the subject. Key Features The improved efficacy of 5-ALA for resecting high- and low-grade gliomas, recurrences, meningiomas, brain metastases, spinal cord tumors, pediatric brain tumors, and other adult tumors The future of fluorescence, including potentially powerful new fluorophores molecularly targeted specifically to tumors The use of the fluorescent agent indocyanine green (ICG) for brain tumors, cerebral aneurysms, AVMs, and cerebral vascularization Special topics such as fluorescein, illuminating tumor paint, confocal microscopy, Raman spectroscopy, and integrating FGS with intraoperative imaging and brain mapping This single accessible reference presents the current state-of-the-art on this emerging, exciting surgical technology. As such, it is a must-have for neurosurgical residents, fellows, and practicing neurosurgeons.

Fluorescence-Guided Neurosurgery

Fluorescence-Guided Neurosurgery PDF Author: Constantinos G. Hadjipanayis
Publisher: Thieme
ISBN: 1626237158
Category : Medical
Languages : en
Pages : 376

Get Book Here

Book Description
The definitive textbook on state-of-the-art fluorescence-guided neurosurgery Advances in fluorescence-guided surgery (FGS) have resulted in a paradigm shift in neurosurgical approaches to neuro-oncological and cerebrovascular pathologies. Edited by two of the foremost authorities on the topic, Fluorescence-Guided Neurosurgery: Neuro-oncology and Cerebrovascular Applications encompasses the depth and breadth of this groundbreaking, still nascent technology. The book reflects significant contributions made by world renowned neurosurgeons Constantinos Hadjipanayis, Walter Stummer, and esteemed contributors on the growing uses of 5-aminolevulinic acid (5-ALA) and other FGS agents. The European Medicine Agency approved 5-ALA in 2007, heralding the birth of FGS globally. In 2017, the U.S. Food and Drug Administration approved 5-ALA (Gleolan) as an imaging agent to facilitate realtime detection and visualization of malignant tissue during glioma surgery. In the two decades since Dr. Stummer's initial description of 5-ALA FGS in a human patient, major strides have been made in its practical applications, leading to improved resection outcomes. As FGS is increasingly incorporated into neurosurgical practice, it holds promise for future innovations. Generously-illustrated and enhanced with online videos, this textbook is the definitive resource on the subject. Key Features The improved efficacy of 5-ALA for resecting high- and low-grade gliomas, recurrences, meningiomas, brain metastases, spinal cord tumors, pediatric brain tumors, and other adult tumors The future of fluorescence, including potentially powerful new fluorophores molecularly targeted specifically to tumors The use of the fluorescent agent indocyanine green (ICG) for brain tumors, cerebral aneurysms, AVMs, and cerebral vascularization Special topics such as fluorescein, illuminating tumor paint, confocal microscopy, Raman spectroscopy, and integrating FGS with intraoperative imaging and brain mapping This single accessible reference presents the current state-of-the-art on this emerging, exciting surgical technology. As such, it is a must-have for neurosurgical residents, fellows, and practicing neurosurgeons.

Local Therapies for Glioma

Local Therapies for Glioma PDF Author: M. Westphal
Publisher: Springer Science & Business Media
ISBN: 9783211403556
Category : Medical
Languages : en
Pages : 204

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Book Description
In addition to surgery and radiotherapy, local treatment modalities for the management of brain tumours are increasingly being developed and clinically tested. This book describes for the first time basic tumour biology as well as all current procedures in progress at the most recent level of knowledge, presented by leading experts in the respective fields. Image guided resection procedures, fluorescence guided surgery, developments in interstitial radiosurgery are addressed, just as intracavitary chemotherapy and all current concepts and studies of interstitial targeted therapy. Owing to its topicality this book will remain for long the standard for this comprehensively treated subject.

ICG Fluorescence Imaging and Navigation Surgery

ICG Fluorescence Imaging and Navigation Surgery PDF Author: Mitsuo Kusano
Publisher: Springer
ISBN: 4431555285
Category : Medical
Languages : en
Pages : 453

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Book Description
This book presents a comprehensive overview and outlook for the future of indocyanine green (ICG) fluorescence navigation surgery, which is attracting clinical interest as a safe and less invasive procedure not only in detecting cerebral vessels, coronary arteries, and biliary trees, but also in identifying sentinel lymph nodes in cancer. The book starts with the characteristics of ICG and photodynamic cameras/endoscopes, followed by detailed descriptions of the applications of ICG fluorescence imaging in various areas such as ocular surgery, neurosurgery, cardiovascular surgery, and plastic surgery. It also covers identifying sentinel lymph nodes in breast cancer as well as cancers of the gastrointestinal tract, and provides valuable information for hepato-biliary-pancreatic surgeons, such as identifying tattooing of liver segments and bile leakage. Written entirely by experts in their respective areas, ICG Fluorescence Imaging and Navigation Surgery offers an essential resource for surgeons operating on cancers and vascular disorders in the brain and cardiovascular systems and in plastic surgery.

Digital Surgery

Digital Surgery PDF Author: Sam Atallah
Publisher: Springer Nature
ISBN: 3030491005
Category : Medical
Languages : en
Pages : 441

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Book Description
​This book provides a trove of insightful perspectives on the current state and the realization of digital surgery. Digital surgery entails the application of artificial intelligence and machine learning toward automation in robotic-assisted surgery. More generally, the objective is to digitally define the patient, the surgical field, and the surgical problem or task at hand; to operate based on information, rather than based on anatomic planes alone. But digital surgery has shapeshifted into other, equally intriguing faces – many of which are exemplified by topics throughout this book. Digital surgery is fundamental to 3D-printed organs, mind-controlled limbs, image-guided navigation, and tele-mentoring. It is the key that unlocks the metaphorical doorway to surgical access, thereby creating a global framework for surgical training, education, planning, and much more. This text provides methods of measurement and perception outside of the human umwelt – including the ability to visualize fields beyond the visible light spectrum, via near infrared fluorescent organic dyes which are rapidly being bioengineered to target specific tumors, as well as native anatomic structures of interest. Written by experts in the field, Digital Surgery is designed to help surgeons operate with an enriched understanding of an individual’s specific attributes: including the human phenome, physiome, microbiome, genome, and epigenome. It also aids surgeons in harnessing the power and fluidity of the cloud, which is emerging as a significant resource for surgeons both regionally and globally.

Staging Laparoscopy

Staging Laparoscopy PDF Author: P. Hohenberger
Publisher: Springer Science & Business Media
ISBN: 3642562906
Category : Medical
Languages : en
Pages : 206

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Book Description
Included here is a discussion of the pathophysiological aspects and risks of laparoscopic staging (such as trocar metastases) on the basis of international experience.

Image-Guided Neurosurgery

Image-Guided Neurosurgery PDF Author: Alexandra J. Golby
Publisher: Academic Press
ISBN: 0128011890
Category : Medical
Languages : en
Pages : 537

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Book Description
Image-Guided Neurosurgery provides readers with an update on the revolutionary improvements in imaging and visualization relating to neurosurgery. From the development of the pneumoencephalogram, to the operating microscope, to cross sectional imaging with CT and later MRI, to stereotaxy and neuronavigation, the ability to visualize the pathology and surrounding neural structures has been the driving factor leading surgical innovation and improved outcomes. The book provides a comprehensive reference on the application of contemporary imaging technologies used in neurosurgery. Specific techniques discussed include brain biopsies, brain tumor resection, deep brain stimulation, and more. The book is ideal for neurosurgeons, interventional radiologists, neurologists, psychiatrists, and radiologists, as well as technical experts in imaging, image analysis, computer science, and biomedical engineering. - A comprehensive reference on image-guided neurosurgery - Includes coverage of neuronavigation in cranial surgery and advanced imaging, including functional imaging, adoption of intra-operative MRI and emerging technologies - Covers all image-guided neurosurgery tools, including robotic surgical devices - Ideal reference for topics relating to neurosurgery, imaging, stereotaxis, radiosurgery, radiology, epilepsy, MRI, the use of medical robotics, lasers, and more

Intraoperative Imaging

Intraoperative Imaging PDF Author: M. Necmettin Pamir
Publisher: Springer Science & Business Media
ISBN: 3211996516
Category : Medical
Languages : en
Pages : 253

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Book Description
Intraoperative imaging technologies have taken an ever-increasing role in the daily practice of neurosurgeons and the increasing attention and interest necessitated international interaction and collaboration. The Intraoperative Imaging Society was formed in 2007. This book brings together highlights from the second meeting of the Intraoperative Imaging Society, which took place in Istanbul-Turkey from June 14 to 17, 2009. Included within the contents of the book is an overview of the emergence and development of the intraoperative imaging technology as well as a glimpse on where the technology is heading. This is followed by in detail coverage of intraoperative MRI technology and sections on intraoperative CT and ultrasonography. There are also sections on multimodality integration, intraoperative robotics and other intraoperative technologies. We believe that this book will provide an up-to date and comprehensive general overview of the current intraoperative imaging technology as well as detailed discussions on individual techniques and clinical results.

Neurophotonics and Brain Mapping

Neurophotonics and Brain Mapping PDF Author: Yu Chen
Publisher: CRC Press
ISBN: 1482236869
Category : Medical
Languages : en
Pages : 587

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Book Description
Understanding how the brain works and developing effective therapeutics are important in advancing neuroscience and improving clinical patient care. Neurophotonics and Brain Mapping covers state-of-the-art research and development in optical technologies and applications for brain mapping and therapeutics. It provides a comprehensive overview of various methods developed using light, both microscopic and macroscopic techniques. Recent developments in minimally-invasive endoscopic imaging of deep brain structure and function, as well as light-based therapy are also reviewed.

Effects of Cancer Treatment on the Nervous System, Volume 2

Effects of Cancer Treatment on the Nervous System, Volume 2 PDF Author: Wolfgang Grisold
Publisher: Cambridge Scholars Publishing
ISBN: 1527564215
Category : Medical
Languages : en
Pages : 406

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Book Description
Cancer is often associated with pain and is a frequent issue in patients with chemotherapy-induced neuropathy. The participation of patients in studies and their influence on study design is important. Patient support groups have been formed for several forms of cancer, and are helpful in dispensing advice. The treatment of cancer patients must include activities of daily living and quality of life. Often, palliative care and end-of-life care are part of the disease trajectory. As this book shows, patients do not have equal access to cancer treatment around the world, and often basic issues as diagnosis, treatment are lacking.

Intraoperative MRI-Guided Neurosurgery

Intraoperative MRI-Guided Neurosurgery PDF Author: Walter A. Hall
Publisher: Thieme
ISBN: 1638533032
Category : Medical
Languages : en
Pages : 599

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Book Description
The definitive reference on intraoperative MR-guided neurosurgery Comprehensive in scope and packed with practical information, Intraoperative MR-Guided Neurosurgery contains detailed coverage of this state-of-the-art technology from the pioneers who developed it. Renowned neurosurgeons and neuroradiologists combine their collective wisdom and experience to demonstrate how MR-guided neuronavigation can be used to view real-time images of a patient's brain during surgery to help remove tumors with greater precision. The authors provide step-by-step descriptions of how to perform procedures, including advice based on their clinical results. Readers will learn about the advantages and drawbacks of the various MR imaging systems, clinical indications for MR-guidance, anesthesia considerations, safety concerns related to working in a magnetic environment, and much more. Features: In-depth coverage of all MR imaging systems helps readers to make informed choices about which technique will best suit their surgical needs Guidelines on the most appropriate imaging sequences for the resection of different types of brain tumors More than 200 high-quality intraoperative photographs taken during actual procedures to orient readers who want to use MRI in the operating room Tips from the experts on safety issues, suitable magnet designs and field strengths, cost and benefit analysis, room design, equipment, and logistics Discussion of other forms of technology that have been combined with intraoperative MR-guidance, such as focused ultrasound, neurosurgical robotics, and other promising innovations This leading-edge text has everything that neurosurgeons, neuroradiologists, and interventionalists need to know to implement an intraoperative MR-guided neurosurgery program.