Breast Cancer Metastasis and Drug Resistance

Breast Cancer Metastasis and Drug Resistance PDF Author: Aamir Ahmad
Publisher: Springer Nature
ISBN: 3030203018
Category : Medical
Languages : en
Pages : 432

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Book Description
Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.

Breast Cancer Metastasis and Drug Resistance

Breast Cancer Metastasis and Drug Resistance PDF Author: Aamir Ahmad
Publisher: Springer Nature
ISBN: 3030203018
Category : Medical
Languages : en
Pages : 432

Get Book Here

Book Description
Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.

F*ck Cancer

F*ck Cancer PDF Author: Jen Meyers
Publisher: Createspace Independent Publishing Platform
ISBN: 9781548184506
Category :
Languages : en
Pages : 78

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Book Description
This book is for you. If you are fighting cancer, this is for you. If your brother, sister, mom, dad, son, daughter, relative, or friend is fighting cancer, this is for you. If you've lost someone to cancer like I have, this is for you. If cancer affects your life in any way, this is for you. The stress of cancer can feel crushing. But perhaps this book can help you get away from it all, if only for a little while, coloring your stress away and infusing your mind and body with some much-needed positivity. Every little bit helps. With 35 gorgeous and inspiring, single-sided, frameable designs inside ranging from simple to intricate, most include uplifting messages...from the socially acceptable "You've got the heart of a fighter" to the cheekily profane "You are stronger than this shit." So find a comfortable place to artistically unwind, raise your spirits, and boost your inner resolve to fight harder and keep going. For yourself and for those you love. You can. You've got this. I believe in you. *A portion of the proceeds from this book will be donated to support research dedicated to finding a cure for cancer. Because fuck cancer.

Metu and Lee Learn about Breast Cancer

Metu and Lee Learn about Breast Cancer PDF Author: Shenin Sachedina
Publisher: Sachedina Med Educ Prod
ISBN: 9780977864805
Category : Breast
Languages : en
Pages : 0

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Book Description
Children learn to deal with the difficult issue of breast cancer.

What the F*ck Just Happened? A Survivors Guide to Life After Breast Cancer.

What the F*ck Just Happened? A Survivors Guide to Life After Breast Cancer. PDF Author: Jen Rozenbaum
Publisher:
ISBN: 9781948604154
Category :
Languages : en
Pages : 206

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Book Description
Struggling to get back to normal life after breast cancer?You were diagnosed with breast cancer and beat it. Congrats! You counted down until the day you could put the journey behind you and return to your life as you knew it before cancer. That day is here and yet you are still asking yourself, "When will things be normal again?". If you have been feeling like you are struggling emotionally, physically and spiritually in your post cancer life, you are not alone. Here's the good news; You have a second chance at life and you aren't going to let it slip you by. This book is for breast cancer survivors who are truly ready to reconstruct their life and feel normal once again. Author and breast cancer survivor Jen Rozenbaum will teach you her methods to help you: Finally feel normal again after cancerGet rid of the numbness and enjoy life againStop living in fear of the cancer returningFeel sexy and feminine again Grab your copy now and get started on the path to discover and live a normal life again

How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease PDF Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728

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Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Breast Cancer Screening

Breast Cancer Screening PDF Author: Nehmat Houssami
Publisher: Academic Press
ISBN: 9780128022092
Category : Medical
Languages : en
Pages : 0

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Book Description
Breast Cancer Screening: Making Sense of Complex and Evolving Evidence covers broad aspects of breast cancer screening specifically focusing on current evidence, emerging evidence, and issues that will be critical for future breast screening practice such as tailored screening and shared decision-making in breast screening. The scope of the book is relevant to a global audience. This book provides balanced perspectives on this increasingly controversial topic, using scientific evidence to explain the evolution of knowledge relating to breast cancer screening. Breast Cancer Screening covers the key points related to this debate including the context of increasingly complex and conflicting evidence, divergent opinions on the benefits and harms of breast screening, and variability in screening practice and outcomes across settings around the world.

Accelerated Partial Breast Irradiation

Accelerated Partial Breast Irradiation PDF Author: David E. Wazer
Publisher: Springer Science & Business Media
ISBN: 3540880062
Category : Medical
Languages : en
Pages : 447

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Book Description
Accelerated partial breast irradiation (APBI) is being rapidly introduced into the clinical management of early breast cancer. APBI, in fact, encompasses a number of different techniques and approaches that include brachytherapy, intraoperative, and external beam techniques. There is currently no single source that describes these techniques and their clinical implementation. This text is a concise handbook designed to assist the clinician in the implementation of APBI. This includes a review of the principles that underlie APBI, a practical and detailed description of each technique for APBI, a review of current clinical results of APBI, and a review of the incidence and management of treatment related complications.

Percutaneous Breast Biopsy

Percutaneous Breast Biopsy PDF Author: Steve H. Parker
Publisher: Raven Press (ID)
ISBN:
Category : Medical
Languages : en
Pages : 200

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Book Description
A comprehensive treatment of large-core needle biopsy, a new technique for the early diagnosis of breast cancer. Considers the history of the technique, equipment, the principles of stereotactic mammography, and several procedures using ultrasound. The roles and perspectives of the pathologist, the nurse, and the technologist are delineated, with the emphasis on teamwork. Also evaluates fine-needle aspiration biopsy. Addressed to radiologists. Highly illustrated. Annotation copyright by Book News, Inc., Portland, OR

Contrast-Enhanced Digital Mammography (CEDM)

Contrast-Enhanced Digital Mammography (CEDM) PDF Author: Jacopo Nori
Publisher: Springer
ISBN: 9783319945521
Category : Medical
Languages : en
Pages : 0

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Book Description
This book offers a comprehensive, practical resource entirely devoted to Contrast-Enhanced Digital Mammography (CEDM), a state-of-the-art technique that has emerged as a valuable addition to conventional imaging modalities in the detection of primary and recurrent breast cancer, and as an important preoperative staging tool for women with breast cancer. CEDM is a relatively new breast imaging technique based on dual energy acquisition, combining mammography with iodine-based contrast agents to display contrast uptake in breast lesions. It improves the sensitivity and specificity of breast cancer detection by providing higher foci to breast-gland contrast and better lesion delineation than digital mammography. Preliminary results suggest that CEDM is comparable to breast MRI for evaluating the extent and size of lesions and detecting multifocal lesions, and thus has the potential to become a readily available, fast and cost-effective examination. With a focus on the basic imaging principles of CEDM, this book takes a practical approach to breast imaging. Drawing on the editors’ and authors’ practical experience, it guides the reader through the basics of CEDM, making it especially accessible for beginners. By presenting the key aspects of CEDM in a straightforward manner and supported by clear images, the book represents a valuable guide for all practicing radiologists, in particular those who perform breast imaging and have recently incorporated or plan to incorporate CEDM into their diagnostic arsenal.

Dietary Phytochemicals in Cancer Prevention and Treatment

Dietary Phytochemicals in Cancer Prevention and Treatment PDF Author: American Institute for Cancer Research
Publisher: Springer Science & Business Media
ISBN: 1461303990
Category : Science
Languages : en
Pages : 349

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Book Description
The sixth annual research conference of the American Institute for Cancer Research was held August 31 and September 1, 1995, at the Loews L'Enfant Plaza Hotel in Washing ton, DC. In view of the promising leads in the diet/nutrition and cancer research field, the conference was devoted to "Dietary Phytochemicals in Cancer Prevention and Treatment. " The number of sessions was increased over that in previous conferences in order to accommodate the topics of interest. The conference overview, entitled "Plants and Cancer: Food, Fiber, and Phytochemicals," provided a framework for the following sessions. In addition, the attendees were reminded that for several decades epidemiologists have noted a lower risk of lung, esophageal, stomach, and colon cancer in populations consuming diets high in fruits and vegetables. However, isolation and ingestion of individual protective factors are not the preferred action since the complexity of the food and the matrix in which nutritional factors are embedded are important. The individual sessions then provided more insight as to why eating fruits and vegetables is associated with a lower risk of cancer. The first of these sessions was on "Isothiocyanates" that induce both the Phase I and Phase II enzymes that increase detoxification and conjugation reactions, thus causing more rapid removal of any xenobiotic or carcinogen. Thus, less carcinogen is available for interaction with DNA or other critical cellular macromolecules.