Connecting Sarcomere Protein Mutations to Pathogenesis in Myopathies

Connecting Sarcomere Protein Mutations to Pathogenesis in Myopathies PDF Author: Jose Renato Pinto
Publisher: Frontiers Media SA
ISBN: 2889639215
Category : Science
Languages : en
Pages : 375

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Book Description


The truth in complexes: why unraveling ion channel multi-protein signaling nexuses is critical for understanding the function of the nervous system

The truth in complexes: why unraveling ion channel multi-protein signaling nexuses is critical for understanding the function of the nervous system PDF Author: Leigh Anne Swayne
Publisher: Frontiers Media SA
ISBN: 2889194450
Category : Ion channels
Languages : en
Pages : 161

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Book Description
In the search for simple explanations of the natural world, its complicated textures are often filed down to a smoothened surface of our liking. The impetus for this Research Topic was borne out of a need to re-ignite interest in the complex – in this case in the context of ion channels in the nervous system. Ion channels are the large proteins that form regulated pores in the membranes of cells and, in the brain, are essential for the transfer, processing and storage of information. These pores full of twists and turns themselves are not just barren bridges into cells. More and more we are beginning to understand that ion channels are like bustling medieval bridges (packed with apartments and shops) rather than the more sleek modern variety – they are dynamic hubs connected with many structures facilitating associated activities. Our understanding of these networks continues to expand as our investigative tools advance. Together these articles highlight how the complexity of ion channel signaling nexuses is critical to the proper functioning of the nervous system.

Endocrinology

Endocrinology PDF Author: Leslie J. DeGroot
Publisher:
ISBN:
Category : Endocrine glands
Languages : en
Pages : 954

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Biology of the NMDA Receptor

Biology of the NMDA Receptor PDF Author: Antonius M. VanDongen
Publisher: CRC Press
ISBN: 142004415X
Category : Medical
Languages : en
Pages : 368

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Book Description
The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written

Chemical Induced Apoptosis

Chemical Induced Apoptosis PDF Author:
Publisher: Nordic Council of Ministers
ISBN: 9789289305143
Category : Apoptosis
Languages : en
Pages : 108

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Signaling and the Cytoskeleton

Signaling and the Cytoskeleton PDF Author: Kermit L. Carraway
Publisher: Springer Science & Business Media
ISBN: 3662129930
Category : Science
Languages : en
Pages : 293

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Book Description
This monograph explores the relationships between cell signaling and the cytoplasmic cytoskeleton in fundamental cell processes, thus bridging the gap between two very active aspects of molecular cell biology. It covers the two main - and reciprocal - questions of these relationships: How are structure and function of the cytoskeleton affected by external signals which impinge on the cell? How does the cytoskeleton influence the cellular signaling processes which determine cell behavior?

Annexins

Annexins PDF Author: Joanna Bandorowicz-Pikula
Publisher: Springer Science & Business Media
ISBN: 9780306478345
Category : Medical
Languages : en
Pages : 298

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Book Description
The Annexins is focused on a specific family of calcium and membrane-binding proteins, annexins, ubiquitously spread within living organisms, including animals, plants and fungi. The volume covers important areas of annexinology. The characterization of structural-functional relationship within the annexin family of proteins, together with emerging transgenic animal models, provides an up-to-date overview of potential physiological roles of annexins. Growing evidence of participation of annexins in human diseases, called annexinopathies, related to disturbances in signal transduction, vesicular traffic, ion homeostasis and energy metabolism within the cell. The book will attract a broad scientific audience, not only scientists interested in annexins, but also others involved in multidisciplinary studies, as well as undergraduate and postgraduate students. It can be used in courses relating to special topics such as calcium homeostasis, calcium-binding proteins, membrane structure and transport properties, various signal transduction pathways, and membrane trafficking.

The Prefrontal Cortex

The Prefrontal Cortex PDF Author: Joaquin M. Fuster
Publisher: Lippincott Williams & Wilkins
ISBN:
Category : Medical
Languages : en
Pages : 364

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Cumulated Index Medicus

Cumulated Index Medicus PDF Author:
Publisher:
ISBN:
Category : Medicine
Languages : en
Pages : 1328

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Jasper's Basic Mechanisms of the Epilepsies

Jasper's Basic Mechanisms of the Epilepsies PDF Author: Jeffrey Noebels
Publisher: OUP USA
ISBN: 0199746540
Category : Medical
Languages : en
Pages : 1258

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Book Description
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.