Filovirus Clinical Management Working Group meeting report, Geneva, Switzerland, 16-17 March 2023

Filovirus Clinical Management Working Group meeting report, Geneva, Switzerland, 16-17 March 2023 PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240089985
Category : Medical
Languages : en
Pages : 34

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Book Description

Filovirus Clinical Management Working Group meeting report, Geneva, Switzerland, 16-17 March 2023

Filovirus Clinical Management Working Group meeting report, Geneva, Switzerland, 16-17 March 2023 PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240089985
Category : Medical
Languages : en
Pages : 34

Get Book Here

Book Description


Global Health Risk Framework

Global Health Risk Framework PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309381029
Category : Medical
Languages : en
Pages : 141

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Book Description
Since the 2014 Ebola outbreak many public- and private-sector leaders have seen a need for improved management of global public health emergencies. The effects of the Ebola epidemic go well beyond the three hardest-hit countries and beyond the health sector. Education, child protection, commerce, transportation, and human rights have all suffered. The consequences and lethality of Ebola have increased interest in coordinated global response to infectious threats, many of which could disrupt global health and commerce far more than the recent outbreak. In order to explore the potential for improving international management and response to outbreaks the National Academy of Medicine agreed to manage an international, independent, evidence-based, authoritative, multistakeholder expert commission. As part of this effort, the Institute of Medicine convened four workshops in summer of 2015 to inform the commission report. The presentations and discussions from the Workshop on Research and Development of Medical Products are summarized in this report.

Novel Technologies for Vaccine Development

Novel Technologies for Vaccine Development PDF Author: Igor S Lukashevich
Publisher: Springer
ISBN: 3709118182
Category : Medical
Languages : en
Pages : 393

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Book Description
This book presents a detailed overview of the development of new viral vector-based vaccines before discussing two major applications: preventive vaccines for infectious diseases and therapeutic cancer vaccines. Viral vector-based vaccines hold a great potential for development into successful pharmaceutical products and several examples at the advanced pre-clinical or clinical stage are presented. Nevertheless, the most efforts were focused on novel and very innovative technologies for new generation of vector-based vaccines. Furthermore, specific topics such as delivery and adjuvant and protection strategies for cell-mediated-based vaccines are presented. Given its scope, the book is a “must read” for all those involved in vaccine development, both in academia and industrial vaccine development.

Global Health Security

Global Health Security PDF Author: Anthony J. Masys
Publisher: Springer Nature
ISBN: 3030234916
Category : Social Science
Languages : en
Pages : 425

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Book Description
With our highly connected and interdependent world, the growing threat of infectious diseases and public health crisis has shed light on the requirement for global efforts to manage and combat highly pathogenic infectious diseases and other public health crisis on an unprecedented level. Such disease threats transcend borders. Reducing global threats posed by infectious disease outbreaks – whether naturally caused or resulting from a deliberate or accidental release – requires efforts that cross the disaster management pillars: mitigation, preparedness, response and recovery. This book addresses the issues of global health security along 4 themes: Emerging Threats; Mitigation, Preparedness, Response and Recovery; Exploring the Technology Landscape for Solutions; Leadership and Partnership. The authors of this volume highlight many of the challenges that confront our global security environment today. These range from politically induced disasters, to food insecurity, to zoonosis and terrorism. More optimistically, the authors also present some advances in technology that can help us combat these threats. Understanding the challenges that confront us and the tools we have to overcome them will allow us to face our future with confidence.

Microbial Pathogenesis: Infection and Immunity

Microbial Pathogenesis: Infection and Immunity PDF Author: Uday Kishore
Publisher: Springer
ISBN: 9781461495291
Category : Medical
Languages : en
Pages : 0

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Book Description
The book starts with dissecting mechanisms underlying viral immune evasion via exploiting the host complement system by vaccinia virus, and by modulating the type 1 interferon response by RNA viruses. Yet another chapter looks into how viroporins expressed by different families of viruses causing influenza A virus, SARS, hepatitis C and HIV interact with several cellular pathways. Understanding of these mechanisms can aid the development of novel potential anti‐viral targets. The chapter on tuberculosis discusses the emerging importance of the innate immune mechanisms against Mycobacterium tuberculosis infection and latency. This book has a strong focus on fungal pathogenesis and immunity, starting with virulence and host factors that attain great importance in candidiasis and associated escape tricks of seriously opportunistic fungi. Two chapters on Aspergillus fumigatus elaborate on the pathogenic mechanisms: first discussing A. fumigatus‐airway epithelium interaction, followed by fungal and host factors that are paramount in the development of allergic and invasive aspergillosis. In the subsequent chapter, there is a general discussion on the innate and adaptive immune responses against primary and opportunistic fungal pathogens.

Infection Prevention

Infection Prevention PDF Author: Gonzalo Bearman
Publisher: Springer
ISBN: 3319609807
Category : Medical
Languages : en
Pages : 311

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Book Description
This book reviews evolving areas in infection prevention on topics including contact precautions, technology implementation, specific infections, and care in various settings. The book summarizes the current data oninfection prevention, presents controversies on the various topics, and includes recommendations for patient safety. Addressing hot topics such as MRSA, C. difficile vaccination, mandatory flu vaccines, and CLABSI, this is the only text to include prevention and control overviews across a range of infection issues. Written by experts in thefield, this book contains 32 chapters that educates and presents the most cutting-edge models of care on emerging and evolving topics in infectious diseases. Infection Prevention: New Perspectives and Controversies is a valuable resource for infection prevention professionals, healthcare quality and safety professionals, caring for patients in in- and outpatient settings.

Sepsis Management in Resource-limited Settings

Sepsis Management in Resource-limited Settings PDF Author: Arjen M. Dondorp
Publisher: Springer
ISBN: 3030031438
Category : Medical
Languages : en
Pages : 226

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Book Description
This book is open access under a CC BY 4.0 license. It constitutes a unique source of knowledge and guidance for all healthcare workers who care for patients with sepsis and septic shock in resource-limited settings. More than eighty percent of the worldwide deaths related to sepsis occur in resource-limited settings in low and middle-income countries. Current international sepsis guidelines cannot be implemented without adaptations towards these settings, mainly because of the difference in local resources and a different spectrum of infectious diseases causing sepsis. This prompted members of the Global Intensive Care working group of the European Society of Intensive Care Medicine (ESICM) and the Mahidol-Oxford Tropical Medicine Research Unit (MORU, Bangkok, Thailand) - among which the Editors – to develop with an international group of experts a comprehensive set of recommendations for the management of sepsis in resource-limited settings. Recommendations are based on both current scientific evidence and clinical experience of clinicians working in resource-limited settings. The book includes an overview chapter outlining the current challenges and future directions of sepsis management as well as general recommendations on the structure and organization of intensive care services in resource-limited settings. Specific recommendations on the recognition and management of patients with sepsis and septic shock in these settings are grouped into seven chapters. The book provides evidence-based practical guidance for doctors in low and middle income countries treating patients with sepsis, and highlights areas for further research and discussion.

Framework for a Public Health Emergency Operations Centre

Framework for a Public Health Emergency Operations Centre PDF Author: World Health Organization
Publisher:
ISBN: 9789241565134
Category : Medical
Languages : en
Pages : 0

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Book Description
The Framework for a Public Health Emergency Operations Centre (PHEOC framework) document is intended to be used by practitioners of public health; health policy makers; and authorities and agencies responsible for managing emergencies, incidents, or events where the health of populations is at risk. This document provides high-level methodical guidance for designing, developing, and strengthening of public health emergency operations centers. This interim document outlines the key concepts and essential requirements for developing and managing a public health EOC (PHEOC). The overall approach is generic and based on widely acknowledged elements of all-hazards emergency management. It provides an outline for developing and managing a PHEOC to achieve a goal-oriented response to public health emergencies and unity of effort among response agencies. The document will be revised as necessary. Practical guidance on specific aspects of the PHEOC framework will be developed and published separately. A public health emergency is here defined as an occurrence, or imminent threat, of an illness or health condition that poses a substantial risk of a significant number of human fatalities, injuries or permanent or long-term disability. Public health emergencies can result from a wide range of hazards and complex emergencies. Experience has shown that timely implementation of an EOC provides an essential platform for the effective management of public health emergencies. Public health emergencies involve increased incidence of illness, injury and/or death and require special measures to address increased morbidity, mortality and interruption of essential health services. For such emergencies, a multi-agency, multi-jurisdictional response is often required, working with the national disaster management organization. When normal resources and capacities are exceeded, support from outside the affected areas will also be required. External assistance could include national, cross-border, regional or international resources.

Coronavirus Disease 2019 (COVID-19)

Coronavirus Disease 2019 (COVID-19) PDF Author: Shailendra K. Saxena
Publisher:
ISBN: 9789811548154
Category : Coronavirus infections
Languages : en
Pages :

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Book Description
This book provides a comprehensive overview of recent novel coronavirus (SARS-CoV-2) infection, their biology and associated challenges for their treatment and prevention of novel Coronavirus Disease 2019 (COVID-19). Discussing various aspects of COVID-19 infection, including global epidemiology, genome organization, immunopathogenesis, transmission cycle, diagnosis, treatment, prevention, and control strategies, it highlights host-pathogen interactions, host immune response, and pathogen immune invasion strategies toward developing an immune intervention or preventive vaccine for COVID-19. An understanding of the topics covered in the book is imperative in the context of designing strategies to protect the human race from further losses and harm due to SARS-CoV-2 infection causing COVID-19.

Climate Information for Public Health Action

Climate Information for Public Health Action PDF Author: Madeleine C. Thomson
Publisher: Routledge
ISBN: 1351631101
Category : Political Science
Languages : en
Pages : 213

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Book Description
Policy-makers are increasingly concerned about the impact of climate variability and change on the health of vulnerable populations. Variations and trends in climatic factors and extreme weather events impact many health outcomes, including malaria, heat stress and undernutrition. Climate Information for Public Health Action is based on the premise that climate knowledge and information can help protect the public from climate-sensitive health risks. With a focus on infectious disease, hydro-meteorological disasters and nutrition, the book explores why, when and how data on the historical, current and future (from days to decades) climate can be incorporated into health decision-making. Created as a collaborative effort between climate and health experts, this book targets a broad technical public health community, alongside development practitioners and policy-makers engaged in climate change adaptation. It may also guide climate experts in the development of climate services tailored to health needs. Written in an accessible, informative style, while maintaining the highest technical and scientific standards, it will also be a valuable resource for students and academics studying and working in the emerging field of environment and health. The Open Access version of this book, available at http://www.tandfebooks.com/doi/view/10.4324/9781315115603, has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4.0 license."