Fatty Acids and Inflammatory Skin Diseases

Fatty Acids and Inflammatory Skin Diseases PDF Author: Schröder
Publisher: Springer
ISBN: 3034887612
Category : Medical
Languages : en
Pages : 182

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Book Description
Fatty acids play an important role in the barrier function of skin and represent a major source of proinflammatory mediators such as prostaglandins, leukotrienes and other lipids in inflammatory skin disorders. This book combines the two major functions of fatty acids in skin biology. In the first part the biosynthesis of fatty acids in skin with its role in barrier function as well as the role of dietary fatty acids on skin cell function and in the treatment of inflammatory skin diseases is presented. The second part deals with skin as a source of proinflammatory eicosanoids, especially with the keratinocyte as a major cellular source. Metabolism of eicosanoids in skin, its role in psoriasis and atopic dermatitis as well as pharmacological inhibition of eicosanoid biosynthesis is reviewed. The book finishes with a chapter describing the methods used for quantification of fatty acids and derivatives in skin inflammation. Anyone interested in skin physiology would benefit from the overviews about the two sites of fatty acids' function in skin integrity and in skin inflammation.

Fatty Acids and Inflammatory Skin Diseases

Fatty Acids and Inflammatory Skin Diseases PDF Author: Schröder
Publisher: Springer
ISBN: 3034887612
Category : Medical
Languages : en
Pages : 182

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Book Description
Fatty acids play an important role in the barrier function of skin and represent a major source of proinflammatory mediators such as prostaglandins, leukotrienes and other lipids in inflammatory skin disorders. This book combines the two major functions of fatty acids in skin biology. In the first part the biosynthesis of fatty acids in skin with its role in barrier function as well as the role of dietary fatty acids on skin cell function and in the treatment of inflammatory skin diseases is presented. The second part deals with skin as a source of proinflammatory eicosanoids, especially with the keratinocyte as a major cellular source. Metabolism of eicosanoids in skin, its role in psoriasis and atopic dermatitis as well as pharmacological inhibition of eicosanoid biosynthesis is reviewed. The book finishes with a chapter describing the methods used for quantification of fatty acids and derivatives in skin inflammation. Anyone interested in skin physiology would benefit from the overviews about the two sites of fatty acids' function in skin integrity and in skin inflammation.

Fatty Acids and Inflammatory Skin Diseases

Fatty Acids and Inflammatory Skin Diseases PDF Author: Jens-Michael Schröder
Publisher: Birkhauser
ISBN: 9780817658472
Category : Medical
Languages : en
Pages : 177

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Book Description


Medicinal Fatty Acids in Inflammation

Medicinal Fatty Acids in Inflammation PDF Author: J. Kremer
Publisher: Springer
ISBN: 3034888252
Category : Medical
Languages : en
Pages : 162

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Book Description
This volume of Progress in Inflammation Research is a unique compilation of work performed by a wide spectrum of investigators from different medical disciplines. It is fascinating that dietary alterations of fatty acid intake can result in a range of salutory changes in a great variety of medical conditions. Most of the good scien tific work which has led to these observations has been performed over just the last two decades. This is of course not a very long time in the context of the history of the human species. Recently performed analysis of fat intake from paleolithic times has indicated that our hunter-gatherer ancestors consumed as much cholesterol as modern Western man, but strikingly less saturated fatty acid and more polyunsatu rates, including n-3 fatty acids. Wild game has the terrestrial source of n-3 incorpo rated in its fat since browsing animals derive 18:3n-3 (alpha-linolenic acid) natural ly from leafy plants. There is, however, little opportunity for modern Western man to get n-3 fatty acids from the diet if one does not consume fish. Modern agribusiness provides ani mal feeds high in n-6 fatty acids, mostly derived from linoleic acid (18:2n-6) in corn feed. Therefore, grazing animals have no access to alternative fatty acids in either feed or grasses, the latter containing little or none of these potentially beneficial highly polyunsaturated fatty acids.

Targeting Human Inflammatory Skin Diseases With Natural Products: Exploring Potential Mechanisms and Regulatory Pathways

Targeting Human Inflammatory Skin Diseases With Natural Products: Exploring Potential Mechanisms and Regulatory Pathways PDF Author: Bey Hing Goh
Publisher: Frontiers Media SA
ISBN: 2889719936
Category : Science
Languages : en
Pages : 157

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Book Description


Bioactive Dietary Factors and Plant Extracts in Dermatology

Bioactive Dietary Factors and Plant Extracts in Dermatology PDF Author: Ronald Ross Watson
Publisher: Springer Science & Business Media
ISBN: 1627031677
Category : Medical
Languages : en
Pages : 538

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Book Description
The role of Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology provides current and concise scientific appraisal of the efficacy of foods, nutrients, herbs, and dietary supplements in preventing dermal damage and cancer as well as improving skin health. This important new volume reviews and presents new hypotheses and conclusions on the effects of different bioactive foods and their components derived particularly from vegetables, fruits, and herbs. Primary emphasis is on treatment and prevention of dermal damage focusing on skin cancers with significant health care costs and mortality. Bioactive Dietary Factors and Plant Extracts in Preventive Dermatology brings together expert clinicians and researchers working on the different aspects of supplementation, foods, and plant extracts and nutrition and skin health. Their expertise provides the most current knowledge in the field and will serve as the foundation for advancing future research.

Eicosanoids and the Skin

Eicosanoids and the Skin PDF Author: Thomas Ruzicka
Publisher: CRC Press
ISBN: 9780849360329
Category : Medical
Languages : en
Pages : 230

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Book Description
This publication summarizes the increasing knowledge in eicosanoid research. It provides a detailed overview of this rapidly expanding field. The text contains sections on general aspects of arachidonic acid metabolism, the role of eicosanoids in skin diseases, and their biological and biochemical effects in skin. Also included is a section on inhibitors of arachidonic acid metabolism with particular reference to use in dermatology. New concepts covered are: possible physiological role of lipoxygenase products in cutaneous wound healing, restoration and maintenance of cutaneous integrity, and the recently recognized protective function of prostaglandins in skin. It is an invaluable resource for individuals involved with dermatology, pharmacology, inflammation, immunology, biochemistry, physiology, internal medicine and therapeutics.

Methodologies, Tools and Techniques to Study Fatty Acids' Mechanisms of Action in Atopic Dermatitis

Methodologies, Tools and Techniques to Study Fatty Acids' Mechanisms of Action in Atopic Dermatitis PDF Author: Keerthi Anantha
Publisher:
ISBN:
Category : Atopic dermatitis
Languages : en
Pages : 118

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Book Description


Nutraceuticals and the Skin: Roles in Health and Disease

Nutraceuticals and the Skin: Roles in Health and Disease PDF Author: Jean Christopher Chamcheu
Publisher: MDPI
ISBN: 3038971928
Category :
Languages : en
Pages : 225

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Book Description
This book is a printed edition of the Special Issue "Nutraceuticals and the Skin: Roles in Health and Disease" that was published in Nutrients

Skin Barrier Function

Skin Barrier Function PDF Author: T. Agner
Publisher: Karger Medical and Scientific Publishers
ISBN: 3318055867
Category : Medical
Languages : en
Pages : 172

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Book Description
Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdisciplinary update offering a wide range of information on the subject. It covers new basic research on skin markers, including results on filaggrin and on methods for the assessment of the barrier function. Biological variation and aspects of skin barrier function restoration are discussed as well. Further sections are dedicated to clinical implications of skin barrier integrity, factors influencing the penetration of the skin, influence of wet work, and guidance for prevention and saving the barrier. Distinguished researchers have contributed to this book, providing a comprehensive and thorough overview of the skin barrier function. Researchers in the field, dermatologists, occupational physicians, and related industry will find this publication an essential source of information.

Epidermal Lipoxygenase Products

Epidermal Lipoxygenase Products PDF Author: Craig Cameron Miller
Publisher:
ISBN:
Category :
Languages : en
Pages : 390

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Book Description