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Author: Rajesh Gupta
Publisher: Springer
ISBN: 3319651064
Category : Medical
Languages : en
Pages : 342
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Book Description
This book offers an overview of the clinical applications of PET/MR imaging through a case-based format. Hybrid PET/MRI provides functional and anatomical information via one setting offering superior imaging quality with lower radiation dose being administered to the patient. The cases in this book focus on the use of this technique in the diagnosis of oncologic, neurologic, cardiovascular, infectious and inflammatory, and pediatric diseases. Each case is presented with the patient history, protocols, interpretation of findings, and pearls and pitfalls accompanied by high quality PET/MR images. The major strength of this book is the discussion of both MRI and PET findings pertinent to each particular case. It expands the discussion of oncologic applications of this modality through a variety of cases that highlight staging, treatment response, and follow up. Illustrating a spectrum of PET/MRI clinical applications, PET/MR Imaging: A Case-Based Approach is a valuable resource for radiologists, nuclear medicine physicians, and residents.
Author: Rajesh Gupta
Publisher: Springer
ISBN: 3319651064
Category : Medical
Languages : en
Pages : 342
Get Book Here
Book Description
This book offers an overview of the clinical applications of PET/MR imaging through a case-based format. Hybrid PET/MRI provides functional and anatomical information via one setting offering superior imaging quality with lower radiation dose being administered to the patient. The cases in this book focus on the use of this technique in the diagnosis of oncologic, neurologic, cardiovascular, infectious and inflammatory, and pediatric diseases. Each case is presented with the patient history, protocols, interpretation of findings, and pearls and pitfalls accompanied by high quality PET/MR images. The major strength of this book is the discussion of both MRI and PET findings pertinent to each particular case. It expands the discussion of oncologic applications of this modality through a variety of cases that highlight staging, treatment response, and follow up. Illustrating a spectrum of PET/MRI clinical applications, PET/MR Imaging: A Case-Based Approach is a valuable resource for radiologists, nuclear medicine physicians, and residents.
Author: Andrea Lenzi
Publisher: Springer
ISBN: 3319090453
Category : Medical
Languages : en
Pages : 346
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Book Description
This book describes in detail the multidisciplinary management of obesity, providing readers with a thorough understanding of the rationale for a multidisciplinary approach and with the tools required to implement it effectively. The emphasis is on a translational approach, starting from basic concepts and fundamental mechanisms of the pathology and clinical morbidity. Experts in the field discuss the full range of relevant topics, including the significance of physical exercise, psychological issues, nutritional strategies, pharmacological options and bariatric surgery. Put another way, the book covers all aspects from the bench to the bedside. Physicians, scientists and postgraduate students will all find it to be invaluable in understanding the causes and optimal management of obesity, which has rapidly become a major public health problem.
Author:
Publisher:
ISBN:
Category : DVD-ROMs
Languages : en
Pages : 1794
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Book Description
Harrison's has defined internal medicine for millions of physicians and students worldwide since 1950. This Seventeenth Edition retains its balance of science and patient management and has been masssively updated to include an innovative array of new features and content. Beyond the expansion of an illustration program with more than 300 new, additional illustrations. The acclaimed "Approach to the Patient" and "Treatment" features have been redesigned to make referencing the content faster than ever before. Readers will find an expanded focus on global health, including a Global Advisory Board composed of 11 prominent medical experts from around the world and a chapter on Global Considerations in Medicine by Jim Kim and Paul Farmer. Also, the new chapter on the Epidemiology of Cardiovascular Diseases provides a uniquely valuable summary of this emerging global epidemic. A new Global Considerations icon identifies epidemiologic, diagnostic, and therapeutic distinctions betwe.
Author: Dominique Heymann
Publisher: Academic Press
ISBN: 0080953883
Category : Medical
Languages : en
Pages : 501
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Book Description
The epidemiological and clinical importance of bone metastasis has long been recognized, but the past decade has seen an explosion in the fields of bone biology and bone cancer research. This period of time has been marked by a number of key discoveries that have led to the opening up of entirely new areas for investigation as well as new therapies which combine surgery and biological therapeutic approaches.Bone is a common site of cancer metastases - cancer cells commonly develop in bone and spread to other organ systems through the bloodstream. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40% in metastatic lung cancer. In clinical terms, bone metastases have substantial negative effects on a patient's quality of life and are a main cause of patient mortality. Given the global prevalence of breast and prostate cancers, knowledge of bone biology has become essential for the medical and cancer research communities. This book provides, all in one resource, the most recent data on bone cancer development (cellular and molecular mechanisms), genomic and proteomic analyses, clinical analyses (histopathology, imaging, pain monitoring), as well as new therapeutic approaches and clinical trials for primary bone tumors and bone metastases. Feature - Presents a comprehensive, translational source for all aspects of bone cancer in one reference work - Bone cancer experts (from all areas of research and practice) take readers from the bench research (cellular and molecular mechanism), through genomic and proteomic analysis, all the way to clinical analysis (histopathology and imaging) and new therapeutic approaches. - Clear presentation by bone biologists of the cellular and molecular mechanisms underlying bone tumors and bone cancer metastasis as well as the genomic and proteomic assays used in detecting cancer within given organ systems - - Clear presentation by oncologists and radiologists of how histopathology, imaging, and pain monitoring can lead to new therapeutic approaches Benefit - Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of bone cancer issues, as opposed to searching through thousands of journal articles. - Provides a common language for cancer researchers, bone biologists, oncologists, and radiologists to discuss bone tumors and how bone cancer metastases affects each major organ system - Correct diagnosis (and therefore correct treatment) of cancer depends on a strong understanding of the molecular basis for the disease – both oncologists and radiologists will benefit - Bone biologists will gain insight into how clinical observations and practices can feed back into the research cycle and will, therefore, be able to develop more targeted genomic and proteomic assays
Author: William P. Cawthorn
Publisher: Frontiers Media SA
ISBN: 288945245X
Category :
Languages : en
Pages : 167
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Book Description
Adipocytes are a major component of the bone marrow, accounting for up to 70% of total bone marrow volume in healthy humans. Indeed, this bone marrow adipose tissue (often referred to as ‘MAT’ or ‘BMAT’) accounts for at least 5% of total adipose tissue mass in lean, healthy humans, suggesting a role in normal physiology and development. Bone marrow adiposity further increases with ageing and in diverse clinical conditions, including major public health challenges such as osteoporosis. Yet despite this abundance and compelling clinical potential, bone marrow adipocytes have received surprisingly little attention from the biomedical research community. Thankfully, this is now beginning to change. Research over the past decade has begun to increase our knowledge of BMAT, including the conditions associated with altered bone marrow adiposity and the potential physiological and pathological functions of bone marrow adipocytes. The articles within this e-Book highlight many of these recent developments, underscoring our increasing knowledge of BMAT formation and function; showcasing emerging techniques for basic and clinical BMAT analysis; and highlighting key questions and future directions for this burgeoning and increasingly diverse field. The editors would like to express their thanks to the authors for contributing the articles within this e-Book; to the senior editors at Frontiers in Endocrinology for their guidance; and to the staff at Frontiers for their helpful input throughout.
Author: A. Mark Davies
Publisher: Springer Science & Business Media
ISBN: 3540779841
Category : Medical
Languages : en
Pages : 694
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Book Description
Detection and characterization of bone tumors with imaging remains a big challenge for every radiologist notwithstanding the impressive progress achieved by the introduction of several new imaging modalities. Moreover, new concepts in surgical and oncological treatment of these lesions require from the radiologist appropriate and focused answers to the specifc questions asked by the referring physicians in order to choose the best therapeutic approach for the in- vidual patient. Tis comprehensive textbook describes in detail the possibilities and limits of all moda- ties, including MRI, CT, nuclear medicine and interventional radiological procedures, employed for the modern imaging of tumoral and tumor-like lesions of bone. Teir role in the diagnosis, surgical staging, biopsy and assessment of response to therapy is discussed in detail, covering all tumor subtypes as well as their specifc anatomical location.Well selected and technically imp- cable illustrations strongly enhance the didactic value of this work. I am very much indebted and grateful to the three editors: A. Mark Davies, Murali Sundaram and Steven L. J. James, world authorities in musculoskeletal radiology, for their superb scientifc achievement in preparing and editing this wonderful volume as well as for their individual ch- ters. I would also like to thank the large international group of collaborating authors, who are also widely acknowledged for their specifc expertise in the area of bone tumors, for their outstanding contributions.
Author: Vassilios Vassiliou
Publisher: Springer
ISBN: 9789402405002
Category : Medical
Languages : en
Pages : 0
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Book Description
The second edition of this book serves both as an introductory and reference book focusing on the field of metastatic bone disease. Featuring contributions from experts in the field, this volume describes the molecular and cellular mechanisms involved in the formation of bone metastases, presents the newer advances made in the understanding of the clinical picture and symptoms of patients, analyses the role of bone markers in research and clinical practice and deals with all aspects of imaging modalities applied for the detection and evaluation of bone metastases. Moreover, the use of all available treatment methods, such as radiotherapy, surgery and systemic treatments for the management of patients with metastatic bone disease is discussed in detail. Overall this volume presents a thorough overview of all aspects of metastatic bone disease and provides a comprehensive and concise information resource for researchers, oncologists, orthopaedic surgeons and clinicians dealing with patients with metastatic bone disease.
Author: William Moy Stratton Russell
Publisher: Hyperion Books
ISBN:
Category : Nature
Languages : en
Pages : 256
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Book Description
Author: James P. Karr
Publisher: Springer Science & Business Media
ISBN: 1461533988
Category : Medical
Languages : en
Pages : 316
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Book Description
The biology of solid tumor metastasis has been the subject of significant scientific and clinical interest for years and while experimental evidence reveals that metastasis is not solely a random event, very little is known about the biology of metastasis originating from prostate cancer. This is in spite of the fact that the majority of prostate cancer patients die with metastatic lesions to the bone. Progress in understanding this most important aspect of prostate cancer has been hampered by the lack of suitable animal models and an inability to accurately quantify bone metastases and their responses to therapy. Over the past decade, scientists in Japan and the United States have steadily advanced our understanding of the cellular, molecular and immunologic biology of primary and disseminated prostate cancer. It is this body of new information, combined with advances in imaging techniques and prostate cancer tumor markers, that prompted the need for an in-depth assessment of bone metastasis of prostate cancer. Accordingly, on December 12, 1990, a group of basic and clinical investigators from Japan and the United States convened in Gotenba, Japan, to hold the first conference devoted solely to the basic biology and clinical aspects of bone metastases originating from prostate cancer. The cross-fertilization of ideas that was fostered through in-depth discussion of technological advances among various basic and clinical disciplines not only further advanced our understanding of prostate metastases to the bone, but suggested approaches for precise quantitative assessment of these lesions and their treatment.
Author: Claude Jasmin
Publisher: John Wiley & Sons
ISBN: 0470011602
Category : Medical
Languages : en
Pages : 582
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Book Description
The epidemiological and clinical importance of bone metastases has long been recognised. For example, the incidence of bone metastases in breast and prostate cancers is 70%, whereas it is only 30 to 40% in metastatic lung cancer. In clinical terms, bone metastases have substantial negative effects on the patient's quality of life. Bone metastases have generally received insufficient attention because of the difficulty in quantifying them, which has left them outside the scope of therapeutic trials This textbook is the result of the remarkable progress made in the understanding of the molecular and cellular mechanisms involved in osteogenesis and osteolysis, and their development for therapeutic purposes. The treatment of malignant hypercalcaemia has also been revolutionised by the use of bisphosphonates. The Textbook of Bone Metastases presents a broad approach to recent progress in all fields related to bone metastases, ranging from epidemiology to the physiopathology of bone metastases and therapeutics. It provides a better understanding of recent advances and, more importantly, will give clinicians all the information needed to help them in the clinical and therapeutic management of patients with bone metastases.
