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Author: Takao K. Hensch
Publisher: Springer Science & Business Media
ISBN: 1461500397
Category : Medical
Languages : en
Pages : 286
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Book Description
A new perspective on brain function depends upon an understanding of the interaction and integration of excitation and inhibition. A recent surge in research activity focused on inhibitory interneurons now makes a more balanced view possible. Technological advances such as improved imaging methods, visualized patch-clamp recording, multiplex single-cell PCR, and gene-targeted deletion or knock-in mice are some of the novel tools featured in this book. This book will provide an integrated view of neuron function, operating in a balanced regime of excitation and inhibition. It is a timely contribution emphasizing how this balance is established, maintained, and modified from the molecular to system levels. The broad spectrum of topics from molecular to cellular and system/computational neuroscience will appeal to a wide audience of advanced graduate students, post-docs, and faculty. Moreover, this book this book features active young researchers from around the world, who are currently educating the brain scientists of tomorrow.
Author: Melanie A. Woodin
Publisher: Springer Science & Business Media
ISBN: 1441969780
Category : Medical
Languages : en
Pages : 191
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Book Description
This volume will explore the most recent findings on cellular mechanisms of inhibitory plasticity and its functional role in shaping neuronal circuits, their rewiring in response to experience, drug addiction and in neuropathology. Inhibitory Synaptic Plasticity will be of particular interest to neuroscientists and neurophysiologists.
Author: Nigel W. Daw
Publisher: Springer Science & Business Media
ISBN: 1475769407
Category : Medical
Languages : en
Pages : 362
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Book Description
As the first introductory-level text in its field, Visual Development offers a comprehensive understanding of the development of the visual system and the effects of visual deprivation. The material is treated from the behavioral, anatomical, and physiological points of view. Complete with ample illustrations and a helpful glossary, this text is invaluable for graduate students, optometry students, and ophthalmology residents as well as for experts in related fields.
Author: Takao K. Hensch
Publisher: Springer Science & Business Media
ISBN: 1461500397
Category : Medical
Languages : en
Pages : 286
Get Book Here
Book Description
A new perspective on brain function depends upon an understanding of the interaction and integration of excitation and inhibition. A recent surge in research activity focused on inhibitory interneurons now makes a more balanced view possible. Technological advances such as improved imaging methods, visualized patch-clamp recording, multiplex single-cell PCR, and gene-targeted deletion or knock-in mice are some of the novel tools featured in this book. This book will provide an integrated view of neuron function, operating in a balanced regime of excitation and inhibition. It is a timely contribution emphasizing how this balance is established, maintained, and modified from the molecular to system levels. The broad spectrum of topics from molecular to cellular and system/computational neuroscience will appeal to a wide audience of advanced graduate students, post-docs, and faculty. Moreover, this book this book features active young researchers from around the world, who are currently educating the brain scientists of tomorrow.
Author: Carson Chow
Publisher: Elsevier
ISBN: 9780444517920
Category : Language Arts & Disciplines
Languages : en
Pages : 876
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Book Description
1. E. Marder, Experimenting with theory -- 2. A. Borysuk and J. Rinzel, Understanding neuronal dynamics by geometrical dissection of minimal models -- 3. D. Terman, Geometry singular perturbation analysis of neuronal dynamics -- 4. G. Mato, Theory of neural synchrony -- 5. M. Shelley, Some useful numerical techniques for simulating integrate-and-fire networks -- 6. D. Golomb, Propagation of pulses in cortical networks: the single-spike approximation -- 7. M. Tsodyks, Activity-dependent transmission in neocortical synapses -- 8. H. Sompolinsky and J. White, Theory of large recurrent networks: from spikes to behavior -- 9. C. van Vreeswijk, Irregular activity in large networks of neurons -- 10. N. Brunel, Network models of memory -- 11. P. Bressloff, Pattern formation in visual cortex -- 12. F. Wolf, Symmetry breaking and pattern selection in visual cortical development -- 13. A. Treves and Y. Roudi, On the evolution of the brain -- 14. E. Brown, Theory of point processes for neural syst ...
Author: Jeffrey Noebels
Publisher: OUP USA
ISBN: 0199746540
Category : Medical
Languages : en
Pages : 1258
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Book Description
Jasper's Basic Mechanisms, Fourth Edition, is the newest most ambitious and now clinically relevant publishing project to build on the four-decade legacy of the Jasper's series. In keeping with the original goal of searching for "a better understanding of the epilepsies and rational methods of prevention and treatment.", the book represents an encyclopedic compendium neurobiological mechanisms of seizures, epileptogenesis, epilepsy genetics and comordid conditions. Of practical importance to the clinician, and new to this edition are disease mechanisms of genetic epilepsies and therapeutic approaches, ranging from novel antiepileptic drug targets to cell and gene therapies.
Author: Li Zhaoping
Publisher: Oxford University Press, USA
ISBN: 0199564663
Category : Medical
Languages : en
Pages : 397
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Book Description
Vision science has grown hugely in the past decades, but there have been few books showing readers how to adopt a computional approach to understanding visual perception, along with the underlying mechanisms in the brain. This book explains the computational principles and models of biological visual processing, and in particular, primate vision.
Author: Davide Martino
Publisher: Oxford University Press
ISBN: 0197543219
Category : Medical
Languages : en
Pages : 577
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Book Description
Tourette syndrome (TS) has become increasingly recognised within society and has gained scientific interest worldwide. Knowledge of its clinical presentation, mechanisms of disease, and available treatment approaches has increased remarkably over the last two decades. Likewise, the way clinicians, teachers, social care workers, and families face the problems manifested by patients with TS is rapidly evolving. Tourette Syndrome, edited by Davide Martino and James F. Leckman, offers a unique opportunity to capture this knowledge advance through a comprehensive and up-to-date overview. Tourette Syndrome covers all the main aspects related to TS, analyzing its complex clinical presentation, the novel viewpoints of causes and mechanisms, state-of-the-art assessment techniques, and the diversity of treatment options. Multidisciplinarity is the main asset of this volume, which represents a source of consultation for a wide audience of professionals, integrated with video tutorials related to particularly complex areas of patient management. Medical and PhD students, as well as post-doctoral scientists, will be able to use the volume as a valuable learning source.
Author: Nicholas T. Carnevale
Publisher: Cambridge University Press
ISBN: 1139447831
Category : Medical
Languages : en
Pages : 399
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Book Description
The authoritative reference on NEURON, the simulation environment for modeling biological neurons and neural networks that enjoys wide use in the experimental and computational neuroscience communities. This book shows how to use NEURON to construct and apply empirically based models. Written primarily for neuroscience investigators, teachers, and students, it assumes no previous knowledge of computer programming or numerical methods. Readers with a background in the physical sciences or mathematics, who have some knowledge about brain cells and circuits and are interested in computational modeling, will also find it helpful. The NEURON Book covers material that ranges from the inner workings of this program, to practical considerations involved in specifying the anatomical and biophysical properties that are to be represented in models. It uses a problem-solving approach, with many working examples that readers can try for themselves.
Author:
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
Neuropsychiatric disorders, covering both psychotic and depressive disorders, but also autism and attention-deficit hyperactivity disorder (ADHD), are characterized by abnormal behavior and brain structure. Accumulating evidence suggests that altered neurochemistry plays a role in these disorders and may have a causal relationship with the observed behavioral and structural abnormalities. To improve the understanding of neurochemical anomalies and (patho)physiological changes in psychiatric conditions, in vivo assessment of the affected tissue, the brain, is wanted and needed. Magnetic resonance spectroscopy (MRS) is a non-invasive technique which allows in vivo assessment of the molecular composition of brain tissues and identification of metabolites involved in physiological and pathological processes, which is otherwise virtually impossible. Only in the last decade with the development of high field MR methodologies, MRS has become sensitive enough for broader use in clinical studies. The implications are many, but proper guidance and elucidation of the pros and cons for the specific methods is needed to optimally exploit the potential. This Research Topic updates the reader on the possibilities and pitfalls of MRS today and highlights methodologies and applications for the future.
Author: Akihiko Takashima
Publisher: Springer Nature
ISBN: 9813293586
Category : Medical
Languages : en
Pages : 405
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Book Description
This book presents essential studies and cutting-edge research results on tau, which is attracting increasing interest as a target for the treatment of Alzheimer's disease. Tau is well known as a microtubule-associated protein that is predominantly localized in the axons of neurons. In various forms of brain disease, neuronal loss occurs, with deposition of hyperphosphorylated tau in the remaining neurons. Important questions remain regarding the way in which tau forms hyperphosphorylated and fibrillar deposits in neurons, and whether tau aggregation represents the toxic pathway leading to neuronal death. With the help of new technologies, researchers are now solving these long-standing questions. In this book, readers will find the latest expert knowledge on all aspects of tau biology, including the structure and role of the tau molecule, tau localization and function, the pathology, drivers, and markers of tauopathies, tau aggregation, and treatments targeting tau. Tau Biology will be an invaluable source of information and fresh ideas for those involved in the development of more effective therapies and for all who seek a better understanding of the biology of the aging brain.
