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Author: Pierre Capy
Publisher: Springer Science & Business Media
ISBN: 9780792346906
Category : Science
Languages : en
Pages : 366
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Book Description
During the last 50 years, the perception oftransposable elements (TEs) has changed considerably from selfish DNA to sequences that may contribute significantly to genome function and evolution. The recent increased interest in TEs is based on the realization that they are a major genetic component (at least 10--20%) of all organisms and a major contributor to the mutation process. It is currently estimated that 70--80% of spontaneous mutations are the result of TE-mediated insertions, deletions, or chromosomal rearrangements. Thus, it seems at least plausible that TEs may playa significant role in the adaptation and evolution of natural populations and species. The ubiquity of TEs suggests that they are an old component of genomes which have been vertically transmitted through generations over evolutionary time. However, detailed analyses carried out over the last 20 years have revealed several unusual features of TE evolution: (i) TEs can be horizontally transferred between species; (ii) TE evolutionary rates can be dramatically increased by specific inactivation processes, such as the RIP (Repeat Induced Point mutation) mechanism in fungi; (iii) TEs can influence the regulation of other TEs by insertion or deletion; (iv) different classes of TEs in even distantly related species can be remarkably similar in both structure and function.
Author: Pierre Capy
Publisher: International Thomson Publishing Services
ISBN:
Category : Science
Languages : en
Pages : 216
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Book Description
This text deals with the evolution of transposable elements (TE). Two main aspects are presented. First, after a description of the main types of elements, their life and death within a species, including regulation of transposition, and their distribution in natural populations and on chromosomes are discussed. Then, the impact of TEs on the host genomes, the putative relationship between environment and transposition rates lead to a discussion of the interaction (or coevolution) between TEs and their host. Second, these results introduce the analysis of the phylogenies of TEs and their interpretations, according to different models i.e. horizontal versus vertical transmission. Finally, the questions of the origin and of the general evolution of TEs is raised from the comparison of conserved regions like reverse transcriptase or transposase-integrase domains.
Author: J. F. McDonald
Publisher: Springer Science & Business Media
ISBN: 9780792363064
Category : Medical
Languages : en
Pages : 314
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Book Description
Once considered merely `selfish' or `parasitic' DNA, transposable elements are today recognized as being of major biological significance. Not only are these elements a major source of mutation, they have contributed both directly and indirectly to the evolution of genome structure and function. On October 8-10, 1999, 100 molecular biologists and evolutionists representing 11 countries met on the campus of The University of Georgia in Athens for the inaugural Georgia Genetics Symposium. The topics of presentations ranged from how the elements themselves have evolved to the impact transposable elements have had on the evolution of their host genomes. The papers in this volume therefore represent state-of-the-art thinking, by leading world experts in the field, on the evolutionary significance of transposable elements.
Author: Nina V. Fedoroff
Publisher: John Wiley & Sons
ISBN: 1118500105
Category : Science
Languages : en
Pages : 240
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Book Description
The transposable genetic elements, or transposons, as they are now known, have had a tumultuous history. Discovered in the mid-20th century by Barbara McClintock, they were initially received with puzzlement. When their genomic abundance began to be apparent, they were categorized as "junk DNA" and acquired the label of parasites. Expanding understanding of gene and genome organization has revealed the profound extent of their impact on both. Plant Transposons and Genome Dynamics in Evolution captures and distills the voluminous research literature on plant transposable elements and seeks to assemble the big picture of how transposons shape gene structure and regulation, as well as how they sculpt genomes in evolution. Individual chapters provide concise overviews of the many flavors of plant transposons and of their roles in gene creation, gene regulation, development, genome evolution, and organismal speciation, as well as of their epigenetic regulation. This volume is essential reading for anyone working in plant genetics, epigenetics, or evolutionary biology.
Author: Jose Luis Garcia Perez
Publisher: Humana
ISBN: 9781493933709
Category : Medical
Languages : en
Pages : 0
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Book Description
This volume covers the latest protocols designed to identify and characterize TEs in genomes, ancient or recently inserted. Additionally, this book includes a series of protocols designed to understand how host genomes act to regulate the activity of TEs, from elegant genetic mobilization assays to key biochemical methods. Finally, this book also includes chapters that describe how TEs can be used for biotechnological applications. Written for the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Transposons and Retrotransposons: Methods and Protocols aims to ensure successful results in the further study of this vital field.
Author: Antonio Fontdevila
Publisher: Oxford University Press
ISBN: 019954137X
Category : Science
Languages : en
Pages : 225
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Book Description
These novelties, among others, are examined in this book in relation to their general significance for evolution, emphasising their human relevance.
Author: Pierre Pontarotti
Publisher: Springer
ISBN: 3319199323
Category : Science
Languages : en
Pages : 406
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Book Description
This book presents 20 selected contributions to the 18th Evolutionary Biology Meeting, which took place in September 2014 in Marseille. They are grouped under the following major themes: · Genotype to Phenotype · Genetic Mechanisms of Diversification · Evolutionary Mechanisms · Speciation and Biodiversity The aims of these annual meetings in Marseille are to bring together leading evolutionary biologists and other scientists who employ evolutionary biology concepts, e.g. for medical research, and to promote the exchange of ideas and encourage interdisciplinary collaborations. Offering an up-to-date overview of recent advances in the field of evolutionary biology, this book represents an invaluable source of information for scientists, teachers and advanced students.
Author: Michael Chandler
Publisher: John Wiley & Sons
ISBN: 1555819214
Category : Science
Languages : en
Pages : 1347
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Book Description
An exploration of the raw power of genetic material to refashion itself to any purpose... Virtually all organisms contain multiple mobile DNAs that can move from place to place, and in some organisms, mobile DNA elements make up a significant portion of the genome. Mobile DNA III provides a comprehensive review of recent research, including findings suggesting the important role that mobile elements play in genome evolution and stability. Editor-in-Chief Nancy L. Craig assembled a team of multidisciplinary experts to develop this cutting-edge resource that covers the specific molecular mechanisms involved in recombination, including a detailed structural analysis of the enzymes responsible presents a detailed account of the many different recombination systems that can rearrange genomes examines the tremendous impact of mobile DNA in virtually all organisms Mobile DNA III is valuable as an in-depth supplemental reading for upper level life sciences students and as a reference for investigators exploring new biological systems. Biomedical researchers will find documentation of recent advances in understanding immune-antigen conflict between host and pathogen. It introduces biotechnicians to amazing tools for in vivo control of designer DNAs. It allows specialists to pick and choose advanced reviews of specific elements and to be drawn in by unexpected parallels and contrasts among the elements in diverse organisms. Mobile DNA III provides the most lucid reviews of these complex topics available anywhere.
Author: Douglas E. Berg
Publisher: Amer Society for Microbiology
ISBN: 9781555810054
Category : Medical
Languages : en
Pages : 972
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Book Description
Documents the remarkable mobility of DNA in procaryotic and eucaryotic genomes: the ability of various DNA segments to move to new sites, to invert, and to undergo deletion or amplification, generally without the extensive DNA sequence homology needed for classical recombination. Seventy contributors explore the mechanisms of these rearrangements, how they are regulated, their biological consequences, and their potential use as research tools. For students and researchers of molecular genetics. Annotation copyrighted by Book News, Inc., Portland, OR
Author: J. F. McDonald
Publisher: Springer
ISBN:
Category : Medical
Languages : en
Pages : 366
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Book Description
In the summer of 1992 a distinguished group of molecular, population and evolutionary geneticists assembled on the campus of the University of Georgia in Athens, USA to discuss the relevance of their research to the role played by transposable elements (TEs) in evolution. The meeting consisted of a series of informal discussions of issues brought up in papers written by the participants and distributed among them prior to the meeting. These papers and the transcripts of the ensuing discussions are presented in this volume.
Author: Tammy A. Morrish
Publisher:
ISBN:
Category :
Languages : en
Pages : 520
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Book Description
