Evaluating Oral, Non-combustible Potential Reduced Exposure Products Marketed to Smokers PDF Download
Are you looking for read ebook online? Search for your book and save it on your Kindle device, PC, phones or tablets. Download Evaluating Oral, Non-combustible Potential Reduced Exposure Products Marketed to Smokers PDF full book. Access full book title Evaluating Oral, Non-combustible Potential Reduced Exposure Products Marketed to Smokers by Caroline Oates Cobb. Download full books in PDF and EPUB format.
Author: Caroline Oates Cobb
Publisher:
ISBN:
Category :
Languages : en
Pages : 186
Get Book Here
Book Description
Potential reduced exposure products (PREPs) are marketed to reduce smoking's harm, despite little information concerning their effects. This study adapts previously reported clinical laboratory methods used to evaluate combustible PREPs to investigate the acute effects of four non-combustible PREPs (Ariva, Camel Snus, Marlboro Snus, Commit nicotine lozenge) relative to own brand cigarettes, sham smoking, and one combustible PREP that delivers no measurable nicotine (Quest). Twenty-eight smokers participated in 7 Latin-squared ordered, 2.5-hr sessions in which each product was administered twice (60-minute inter-administration interval). Sessions differed by product and were separated by > 48 hours. Plasma nicotine, heart rate, expired air carbon monoxide (CO), and subjective effects were assessed. Relative to own brand, non-combustible PREPs decreased nicotine and CO exposure, did not suppress abstinence symptoms fully, and were less acceptable. These short-term clinical laboratory methods are reliable and provide valuable information concerning non-combustible PREPs for smokers.
Author: Caroline Oates Cobb
Publisher:
ISBN:
Category :
Languages : en
Pages : 186
Get Book Here
Book Description
Potential reduced exposure products (PREPs) are marketed to reduce smoking's harm, despite little information concerning their effects. This study adapts previously reported clinical laboratory methods used to evaluate combustible PREPs to investigate the acute effects of four non-combustible PREPs (Ariva, Camel Snus, Marlboro Snus, Commit nicotine lozenge) relative to own brand cigarettes, sham smoking, and one combustible PREP that delivers no measurable nicotine (Quest). Twenty-eight smokers participated in 7 Latin-squared ordered, 2.5-hr sessions in which each product was administered twice (60-minute inter-administration interval). Sessions differed by product and were separated by > 48 hours. Plasma nicotine, heart rate, expired air carbon monoxide (CO), and subjective effects were assessed. Relative to own brand, non-combustible PREPs decreased nicotine and CO exposure, did not suppress abstinence symptoms fully, and were less acceptable. These short-term clinical laboratory methods are reliable and provide valuable information concerning non-combustible PREPs for smokers.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 030946837X
Category : Medical
Languages : en
Pages : 775
Get Book Here
Book Description
Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.
Author: Catherine St. Hilaire
Publisher:
ISBN:
Category : Products liability
Languages : en
Pages : 190
Get Book Here
Book Description
A new study from the Life Sciences Research Office, Inc. (LSRO), Scientific Methods to Evaluate Potential Reduced-Risk Tobacco Products, outlines laboratory and clinical testing approaches for the assessment of tobacco products with the potential to reduce the risks of cigarette smoking for individuals who switch from cigarettes to these products. This report and the scientific evaluation approach outlined by LSRO will be of interest to a number of audiences including academic, government and industry researchers; tobacco control and public health organizations; agencies with regulatory oversight of tobacco products, such as the Federal Trade Commission; as well as individuals involved in the development of legislation providing regulatory authority over tobacco products to public health organizations, such as the Food and Drug Administration, and agency staff. The report will also be of interest to current smokers (and their friends and family) who are unable or unwilling to quit smoking but are interested in reducing their risks due to smoking. This report was produced under a contract between Philip Morris USA, Inc. (Philip Morris) and LSRO. Findings, conclusions, and recommendations were developed independently of Philip Morris and represent the views of LSRO. - Publishers website.
Author: United States. Congress. House. Committee on Government Reform
Publisher:
ISBN:
Category : Medical
Languages : en
Pages : 364
Get Book Here
Book Description
Author: Alison B. Breland
Publisher:
ISBN:
Category : Smoking cessation products
Languages : en
Pages : 320
Get Book Here
Book Description
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309223989
Category : Medical
Languages : en
Pages : 370
Get Book Here
Book Description
Smoking-related diseases kill more Americans than alcohol, illegal drugs, murder and suicide combined. The passage of the Family Smoking Prevention and Tobacco Control Act of 2009 gave the FDA authority to regulate "modified risk tobacco products" (MRTPs), tobacco products that are either designed or advertised to reduce harm or the risk of tobacco-related disease. MRTPs must submit to the FDA scientific evidence to demonstrate the product has the potential to reduce tobacco related harms as compared to conventional tobacco products. The IOM identifies minimum standards for scientific studies that an applicant would need to complete to obtain an order to market the product from the FDA.
Author: Jennifer Nicole Gray
Publisher:
ISBN:
Category :
Languages : en
Pages : 236
Get Book Here
Book Description
Author:
Publisher: ScholarlyEditions
ISBN: 1464965196
Category : Technology & Engineering
Languages : en
Pages : 1063
Get Book Here
Book Description
Issues in Applied Agriculture / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Applied Agriculture. The editors have built Issues in Applied Agriculture: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Applied Agriculture in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Applied Agriculture: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author: United States. Public Health Service. Office of the Surgeon General
Publisher:
ISBN:
Category : Government publications
Languages : en
Pages : 728
Get Book Here
Book Description
This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241209895
Category : Law
Languages : en
Pages : 236
Get Book Here
Book Description
This report presents the conclusions reached and recommendations made by the members of the WHO Study Group on Tobacco Product Regulation (TobReg) at its seventh meeting in December 2013 during which it reviewed background papers specially commissioned for the meeting and which dealt respectively with the following four themes: Novel tobacco products including potential reduced exposure products ; Smokeless tobacco products: research needs and regulatory recommendations ; Reduced ignition propensity cigarettes: research needs and regulatory recommendations and Non-exhaustive priority list of toxic contents and emissions of tobacco products. The Study Group's recommendations in relation to each theme are set out at the end of the section dealing with that theme; its overall recommendations are summarized in Chapter 6.
