Author: A. Yu Konobeyev
Publisher: KIT Scientific Publishing
ISBN: 3866449240
Category : Computer codes
Languages : en
Pages : 398

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Book Description

Author: Konobeyev, A. Yu.
Publisher: KIT Scientific Publishing
ISBN: 3731502852
Category : Nuclear reactions
Languages : en
Pages : 186

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Book Description

Author: I. Hamerton
Publisher: Springer Science & Business Media
ISBN: 9401113262
Category : Technology & Engineering
Languages : en
Pages : 374

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Book Description
After epoxy resins and polyimides, cyanate esters arguably form the most well-developed group of high-temperature, thermosetting polymers. They possess a number of desirable performance characteristics which make them of increasing technological importance, where their somewhat higher costs are acceptable. The principal end uses for cyanate esters are as matrix resins for printed wiring board laminates and structural composites. For the electronics markets, the low dielectric loss characteristics, dimen sional stability at molten solder temperatures and excellent adhesion to conductor metals at temperatures up to 250°C, are desirable. In their use in aerospace composites, unmodified cyanate esters offer twice the frac ture toughness of multifunctional epoxies, while achieving a service tem perature intermediate between epoxy and bis-maleimide capabilities. Applications in radome construction and aircraft with reduced radar signatures utilize the unusually low capacitance properties of cyanate esters and associated low dissipation factors. While a number of commercial cyanate ester monomers and prepoly mers are now available, to date there has been no comprehensive review of the chemistry and recent technological applications of this versatile family of resins. The aims of the present text are to present these in a com pact, readable form. The work is primarily aimed at materials scientists and polymer technologists involved in research and development in the chemical, electronics, aerospace and adhesives industries. It is hoped that advanced undergraduates and postgraduates in polymer chemistry and technology, and materials science/technology will find it a useful introduc tion and source of reference in the course of their studies.

Author: Md. Shahidul Islam
Publisher: Springer Nature
ISBN: 3030124576
Category : Medical
Languages : en
Pages : 1103

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Book Description
This volume contains a unique selection of chapters covering a wealth of contemporary topics in this ubiquitous and diverse system of cell signaling. It offers much more than the accessibility and authority of a primary text book, exploring topics ranging from the fundamental aspects of calcium signaling to its varied clinical implications. It presents comprehensive discussion of cutting-edge research alongside detailed analysis of critical issues, at the same time as setting out testable hypotheses that point the way to future scientific endeavors. The contributions feature material on theoretical and methodological topics as well as related subjects including mathematical modeling and simulations. They examine calcium signaling in a host of contexts, from mammalian cells to bacteria, fruit fly and zebrafish. With much of interest to newcomers to the field as well as seasoned experts, this new publication is both wide-ranging and authoritative. The chapter “Calcium Signaling: From Basic to Bedside” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Author: Yamume Tshomba
Publisher: Springer
ISBN: 3319947613
Category : Medical
Languages : en
Pages : 409

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Book Description
This book shows how new technologies and technical skills together with deeper understanding of pathophysiology of visceral and renal ischemia have contributed to significant improvements in the clinical outcomes in patients undergoing complex aortic repair involving splanchnic arteries. In recent years, aortic repair has expanded its borders, focusing more and more on the particularly challenging segments from which critical branches originate. Optimal results in this area are obtained through a multidisciplinary approach based on crucial elements such as sophisticated imaging techniques, advanced anesthesiological and pharmacological strategies, as well as updated surgical techniques and devices able to reduce ischemic injuries. The book presents problems tackled from different perspectives, by analyzing the main technical aspects of the surgical technique but also functional and metabolic issues. It also discusses concepts such as ischemic preconditioning and ischemia-reperfusion mechanisms, as well as innovative investigational approaches. In the “endovascular era”, it highlights the most recent updates in complex endovascular repair involving renal and visceral arteries, providing both practical tips and tricks and outcomes analyses. The volume also addresses specific, rarely reported problems in vascular surgery, including issues in renal transplant, oncologic surgery with involvement of splanchnic arteries and of the vena cava, and use of the deep veins in aortic surgery. This volume represents a powerful tool for both young and experienced operators who wish to approach the complex aortic pathology either by open surgery or through endovascular methods.”

Author: Seyed Ehtesham Hasnain
Publisher: Springer
ISBN: 9789813294127
Category : Medical
Languages : en
Pages : 514

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Book Description
This book reviews recent advances in the molecular and infection biology, pathology, and molecular epidemiology of Mycobacterium tuberculosis, as well as the identification and validation of novel molecular drug targets for the treatment of this mycobacterial disease. Despite being completely curable, tuberculosis is still one of the leading global causes of death. M. tuberculosis, the causative organism – one of the smartest pathogens known – adopts highly intelligent strategies for survival and pathogenesis. Presenting a wealth of information on the molecular infection biology of M. tuberculosis, as well as nontuberculous mycobacteria (NTM), the book provides an overview of the functional role of the PE/PPE group of proteins, which is exclusive to the genus Mycobacteria, of host-pathogen interactions, and virulence. It also explores the pathogenesis of the infection, pathology, epidemiology, and diagnosis of NTM. Finally it discusses current and novel approaches in vaccine development against tuberculosis, including the role of nanotechnology. With state-of-the-art contributions from experts in the respective domains, this book is an informative resource for practitioners as well as medical postgraduate students and researchers.

Author: Shayne Cox Gad
Publisher: John Wiley & Sons
ISBN: 0470249021
Category : Medical
Languages : en
Pages : 1352

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Book Description
A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for current methods and techniques. Each chapter is written by one or more leading experts in the field. These authors, representing the many disciplines involved in preclinical toxicology screening and testing, give you the tools needed to apply an effective multidisciplinary approach. The editor has carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear. Among the key topics covered are: * Modeling and informatics in drug design * Bioanalytical chemistry * Absorption of drugs after oral administration * Transporter interactions in the ADME pathway of drugs * Metabolism kinetics * Mechanisms and consequences of drug-drug interactions Each chapter offers a full exploration of problems that may be encountered and their solutions. The authors also set forth the limitations of various methods and techniques used in determining the safety and efficacy of a drug during the preclinical stage. This publication should be readily accessible to all pharmaceutical scientists involved in preclinical testing, enabling them to perform and document preclinical safety tests to meet all FDA requirements before clinical trials may begin.

Author: Gajja S. Salomons
Publisher: Springer Science & Business Media
ISBN: 1402064861
Category : Medical
Languages : en
Pages : 359

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Book Description
This volume places emphasis on the intricate interplay between creatine and creatine kinase function on one hand and proper brain function, neurodegenerative disease and/or neuroprotection on the other. The book, compiled by outstanding experts, provides a key reference summarizing the state-of-the-art in creatine and creatine kinase research. It is a must-read for understanding the links between creatine metabolism and neuroprotection as well as neurodegenerative disease.

Author: United States. Social Security Administration
Publisher:
ISBN:
Category : Hospitals
Languages : en
Pages : 72

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Book Description

Author: Paul Heitjans
Publisher: Springer Science & Business Media
ISBN: 3540309705
Category : Science
Languages : en
Pages : 971

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Book Description
This comprehensive, handbook-style survey of diffusion in condensed matter gives detailed insight into diffusion as the process of particle transport due to stochastic movement. It is understood and presented as a phenomenon of crucial relevance for a large variety of processes and materials. In this book, all aspects of the theoretical fundamentals, experimental techniques, highlights of current developments and results for solids, liquids and interfaces are presented.