Heparin-Induced Thrombocytopenia PDF Download
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Author: Theodore Warkentin
Publisher: CRC Press
ISBN: 0824758846
Category : Medical
Languages : en
Pages : 660
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Book Description
Taking stock of advances in clinical recognition, laboratory testing, and pharmacologic therapy as well as basic aspects of pathogenesis, the Third Edition of Heparin-Induced Thrombocytopenia reinforces its standing as the leading guide to accurate diagnosis and effective management of this complex condition. Featuring added chapters on bivalirudin
Author: Theodore Warkentin
Publisher: CRC Press
ISBN: 0824758846
Category : Medical
Languages : en
Pages : 660
Get Book Here
Book Description
Taking stock of advances in clinical recognition, laboratory testing, and pharmacologic therapy as well as basic aspects of pathogenesis, the Third Edition of Heparin-Induced Thrombocytopenia reinforces its standing as the leading guide to accurate diagnosis and effective management of this complex condition. Featuring added chapters on bivalirudin
Author: Antonio Serrano
Publisher:
ISBN:
Category :
Languages : en
Pages : 0
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Book Description
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author: Paolo Gresele
Publisher: Springer
ISBN: 9783642294228
Category : Medical
Languages : en
Pages : 0
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Book Description
Antiplatelet therapy is the cornerstone of treatment of ischemic cardiovascular disease and over the last few years spectacular advancements in this field have been recorded. This is the first comprehensive handbook entirely dedicated to all the aspects of antiplatelet therapy. The book is divided into three main sections, pathophysiology, pharmacology and therapy, for a total of 23 chapters. A large group of leading experts from different European countries and from the USA, both from academia and industry, have contributed to the book. Besides a detailed overview on the pharmacology and clinical applications of all the currently used or of the novel antiplatelet agents, innovative approaches (e.g. intracellular signalling as an antiplatelet target, small RNAs as platelet therapeutics, etc.) or unconventional aspects (e.g. pharmacologic modulation of the inflammatory action of platelets are also treated. The book is oriented to both basic investigators and to clinicians involved with research on platelet inhibition or with the clinical use of antiplatelet therapies.
Author: Dorian Teissandier
Publisher:
ISBN:
Category :
Languages : fr
Pages :
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Book Description
Les hémorragies sous anticoagulant oraux (ACO) sont des motifs fréquents de consultation aux urgences et leur prise en charge est codifiées par des recommandations ou propositions d'experts. En cas d'hémorragie grave sous ACO et en l'absence d'antidote, les agents utilisés pour antagoniser l'effet anticoagulant sont des facteurs procoagulants : complexes prothrombiniques activés (CCPa) ou des concentrés de complexes prothrombiniques (CCP). Comparaison des paramètres de génération de thrombine (GT) chez 3 populations de patients sous ACO : patients avec accidents hémoragiques graves ayant reçu des facteurs pro-coagulants dans le cadre de la réversion, patients avec hémorragie non grave sans réversion et patients anticoagulés sans accident hémorragique. Etude prospective, descriptive, monocentrique de la GT chez les patients présentant une hémorragie non grave (non reversée) ou mettant en jeu le pronostic vital et/ou fonctionnel sous ACO (AVK, rivaroxaban, dabigatran, apixaban) réversée par CCP, CCPa ou idarucizumab. L'étude a été réalisée sur plasma pauvre en plaquettes prélevé à l'arrivée (V1) avant la réversion, puis 30 min (V2), 6h (V3) et 24h (V4) après la réversion. 307 patients ont été inclus dans cette étude (98 patients avec hémorragie grave réversés dont 61 AVK, 13 rivaroxaban, 17 apixaban et 7 dabigatran), 95 patients sans hémorragie grave non réversés (44 AVK, 25 rivaroxaban, 24 apixaban et 2 dabigatran), 108 patients contrôles sous ACO sans saignement). Pour les V1, les patients sous AVK avec hémorragie réversée présentaient une diminution significative des principaux paramètres de GT (ETC et pic) en comparaison aux patients sans hémorragie (p =0, 017). Il ne semblait pas exister de différence significative pour le rivaroxaban l'apixaban et le dabigatran entre les 3 populations à V1. Au même temps V1, les principaux paramètres de la GT (ETP et pic) étaient significativement diminués pour les AVK en comparaison aux AOD (p
Author: Joe F. Lau
Publisher: Springer
ISBN: 3319737090
Category : Medical
Languages : en
Pages : 464
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Book Description
This book presents the latest evidence and guidelines supporting the use of anticoagulant therapy for various clinical scenarios. The field of anticoagulation therapy is evolving rapidly, particularly since the arrival and widespread adoption of direct oral anticoagulants. Organized in two parts, this book reviews the pharmacologic properties of various anticoagulants and details the clinical applications of anticoagulant therapy. Drugs such as warfarin and unfractionated heparin, as well as parenteral and direct oral anticoagulants are discussed in terms of their pharmacokinetics, drug-disease interactions, dosing strategies, and risk considerations. Clinical applications of anticoagulant therapy in disorders such as acute coronary syndromes, atrial fibrillation, and thrombophilia and in special populations such as pregnant women, the elderly, and in the patient with cancer are highlighted. Clinical vignettes, algorithms, clinical pearls, and self-assessment questions are integrated throughout the book. Featuring contributions from authorities in the field, Anticoagulation Therapy is an essential resource for cardiologists, vascular medicine specialists, hematologists, internists, and all other healthcare professionals who prescribe anticoagulants.
