Author: Xiao-Wei Gao
Publisher: Cambridge University Press
ISBN: 9780521773591
Category : Science
Languages : en
Pages : 274
Get Book Here
Book Description
Nonlinear stress analysis (a branch of solid mechanics) is an essential feature in the design of such diverse structures as aircraft, bridges, machines, and dams. Computational techniques have become vital tools in dealing with the complex, time-consuming problems associated with nonlinear stress analysis. Although finite element techniques are widely used, boundary element methods (BEM) offer a powerful alternative, especially in tackling problems of three-dimensional plasticity. This book describes the application of BEM in solid mechanics, beginning with basic theory and then explaining the numerical implementation of BEM in nonlinear stress analysis. The book includes a state-of-the-art CD-ROM containing BEM source code for use by the reader. This book will be especially useful to stress analysts in industry, research workers in the field of computational plasticity, and postgraduate students taking courses in engineering mechanics.
Author: Jean Lemaitre
Publisher: Springer Science & Business Media
ISBN: 3662027615
Category : Science
Languages : en
Pages : 225
Get Book Here
Book Description
A new branch of science usually develops thus. Somebody publishes the basic ideas. Hesitatingly at first, then little by little, other original contributions appear, until a certain threshold is reached. Then, overview articles are printed, conferences are held, and a first mention is made in textbooks, until specialized monographs are written. Continuum darnage mechanics has reached that status now. To analyze or, if possible, to predict the failure of machine parts or other structures is one of the main goals of engineering science. Consequently fracture mechanics became one of its leading branches. It was based on the analysis of existing cracks. However, especially under conditions of cyclic loading, this might be too late to prevent a disaster. Therefore, the question regarding the precursory state, that is, the evolution of intemal darnage before macrocracks become visible, was then posed. One of the successful approaches to the problern was Weibull's theory which examined, in a statistical manner, the "weakest link" in the material volume under consideration. Unfortunately it proved too difficult mathematically to be applied to complicated parts or structures. Therefore it was highly appreciated by the scientific of material community when L. M. Kachanov published in 1958 a simple model darnage which subsequently could be extended to brittle elastic, plastic or viscous materials under all conditions of uniaxial or multiaxial, simple or cyclic loadings, so that it may be considered nearly universal.
Author: David Mittelman
Publisher: Springer Science & Business Media
ISBN: 1461462800
Category : Medical
Languages : en
Pages : 284
Get Book Here
Book Description
The discovery of stress-induced mutagenesis has changed ideas about mutation and evolution, and revealed mutagenic programs that differ from standard spontaneous mutagenesis in rapidly proliferating cells. The stress-induced mutations occur during growth-limiting stress, and can include adaptive mutations that allow growth in the otherwise growth-limiting environment. The stress responses increase mutagenesis specifically when cells are maladapted to their environments, i.e. are stressed, potentially accelerating evolution then. The mutation mechanism also includes temporary suspension of post-synthesis mismatch repair, resembling mutagenesis characteristic of some cancers. Stress-induced mutation mechanisms may provide important models for genome instability underlying some cancers and genetic diseases, resistance to chemotherapeutic and antibiotic drugs, pathogenicity of microbes, and many other important evolutionary processes. This book covers pathways of stress-induced mutagenesis in all systems. The principle focus is mammalian systems, but much of what is known of these pathways comes from non-mammalian systems.
Author: United States. Ship Structure Committee
Publisher:
ISBN:
Category : Naval research
Languages : en
Pages : 344
Get Book Here
Book Description
Author: Cheryl S. Rosenfeld
Publisher: Academic Press
ISBN: 0128016728
Category : Science
Languages : en
Pages : 562
Get Book Here
Book Description
Winner of 2016 BMA Medical Award for Basic and Clinical Sciences The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother's diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of our children, possibly leading to metabolic, cardiovascular, immunological, neurobehavioral disorders, and increased risk for cancer to list but a few examples. - Informs how everyday choices pregnant women make can impact child development - Ties together how in utero environmental changes may be inducing epigenetic changes in the offspring leading to overlapping phenotypes regardless of the initial insult (toxic, nutrition, or stress) - Includes a boxed-in area in each chapter for further references and resources to keep up with the field - Features video interviews with the authors and other key leaders in the field
Author:
Publisher:
ISBN:
Category : Periodicals
Languages : en
Pages : 912
Get Book Here
Book Description
Author: Matthew C. Gutmann
Publisher: Univ of California Press
ISBN: 9780520250130
Category : Social Science
Languages : en
Pages : 372
Get Book Here
Book Description
Praise for the first edition: "Gutmann has done the hithertofore seemingly unthinkable. [A] wholly other vision of Mexican gender relations emerges."—José Limón, American Anthropologist "This book does for the study of men what two generations of feminist anthropologists have done for the study of women."—Lynn Stephen, author of Zapotec Women
Author: Douglas D. Richman
Publisher: John Wiley & Sons
ISBN: 1555819435
Category : Medical
Languages : en
Pages : 1473
Get Book Here
Book Description
The essential reference of clinical virology Virology is one of the most dynamic and rapidly changing fields of clinical medicine. For example, sequencing techniques from human specimens have identified numerous new members of several virus families, including new polyomaviruses, orthomyxoviruses, and bunyaviruses. Clinical Virology, Fourth Edition, has been extensively revised and updated to incorporate the latest developments and relevant research. Chapters written by internationally recognized experts cover novel viruses, pathogenesis, epidemiology, diagnosis, treatment, and prevention, organized into two major sections: Section 1 provides information regarding broad topics in virology, including immune responses, vaccinology, laboratory diagnosis, principles of antiviral therapy, and detailed considerations of important organ system manifestations and syndromes caused by viral infections. Section 2 provides overviews of specific etiologic agents and discusses their biology, epidemiology, pathogenesis of disease causation, clinical manifestations, laboratory diagnosis, and management. Clinical Virology provides the critical information scientists and health care professionals require about all aspects of this rapidly evolving field.
Author: Howard Kassinove
Publisher: Taylor & Francis
ISBN: 1317822641
Category : Psychology
Languages : en
Pages : 268
Get Book Here
Book Description
Anger is a daily experience. It is encountered in a number of interpersonal, family and occupational situations. Research indicates that even "normal" parents worry that they will lose control of their anger and harm their children. When short-lived and of low intensity, anger may be of some help to us; in contrast, when it is persistent and intense, it is typically highly disruptive.; This text reviews facts and theories of anger. Anger is differentiated from annoyance, fury, rage, hostility and the behaviours of aggression and violence, and attention is paid to understanding anger both as a normal experience and as a clinical disorder. Specific anger diagnoses are presented to describe disruptive anger states and traits. Anger in criminal populations is also discussed and behaviour-analytic, cognitive-constructivist and cross-cultural perspectives are presented in detail.; The book argues that it is important to understand the causes, correlations and outcomes of anger and to develop effective remediation programmes when anger is excessive and disruptive. Thus, following a meta-analyses of the effectiveness of published treatments, two chapters present "ideal" therapy programmes for adult and childhood adolescent anger disorders. Finally, a model is presented to help understand anger development and resolution.
Author: Lisa Hark
Publisher: John Wiley & Sons
ISBN: 1118374541
Category : Medical
Languages : en
Pages : 400
Get Book Here
Book Description
The Nurse Practitioner’s Guide to Nutrition is a comprehensive clinical resource for nurse practitioners working in a variety of clinical care settings. Emphasizing practical nutrition information, this accessible guide provides guidance on incorporating nutrition history questions and counselling techniques into routine care across all clinical settings. The book begins by discussing fundamental concepts in nutrition assessment, giving readers a solid framework from which to approach subsequent chapters. Section Two focuses on nutrition from a lifespan perspective, organizing information by the issues most pertinent to patients at different stages of life. Section Three presents nutrition counselling across clinical care settings ranging from cardiology, endocrinology, oncology, and gastroenterology to caring for the obese patient. Each chapter includes essential information distilled in quick-access tabular format and clinical scenarios that apply key concepts discussed to real-world examples. Ideal for both in-training and qualified advanced practice nurses, The Nurse Practitioner’s Guide to Nutrition is an essential tool for assessing, managing, and treating nutrition-related conditions, as well as promoting nutritional health for all patients. This activity has been approved for 35 nursing continuing education contact hours through the Temple University College of Health Professions and Social Work Department of Nursing Provider Unit, an approved provider of continuing nursing education by the Pennsylvania State Nurses Association, itself an accredited approver by the American Nurses Credentialing Center’s Commission on Accreditation. For e-book users: CNE materials are available for download after purchase. This title is also available as a mobile App from MedHand Mobile Libraries. Buy it now from Google Play or the MedHand Store.
