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Author: Ashutosh Kar
Publisher: Elsevier Health Sciences
ISBN: 813123262X
Category : Medical
Languages : en
Pages : 370
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Book Description
Essentials of Biopharmaceutics and Pharmacokinetics Kar’s Essentials of Biopharmaceutics and Pharmacokinetics deals with how a drug exerts its action in the human body through the fundamentals of absorption, distribution, metabolism and excretion. The book adopts a growth-oriented format and design that is developed systematically and methodically. The book interrelates five different sections: Section 1 Biopharmaceutics and Pharmacokinetics: What Do They Mean? Section 2 Biopharmaceutics Section 3 Pharmacokinetics Section 4 Clinical Pharmacokinetics Section 5 Bioavailability and Bioequivalence Each section starts with a basic theory and fields of application, focuses on model-independent pharmacokinetic analyses, expatiates various biopharmaceutical aspects of dosage form and evaluation, provides an altogether new approach in understanding both dosage regimen design and individualization, and explains modification in drug molecules related to the pharmacokinetics. Undoubtedly, the unique blend of fundamental principles and latest breakthroughs in the field will certainly provide sufficient subject matter to the students of pharmacy, pharmacology, medicinal chemistry scientists, who need a simple as well as detailed introduction in theory and application.
Author: Kar
Publisher: Elsevier Health Sciences
ISBN: 8131226395
Category :
Languages : en
Pages : 370
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Book Description
Author: Notari
Publisher: CRC Press
ISBN: 9780824775230
Category : Science
Languages : en
Pages : 448
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Book Description
Cover -- Half Title -- Title Page -- Copyright Page -- Dedication -- Table of Contents -- Preface to the Fourth Edition -- Preface to the Third Edition -- Preface to the Second Edition -- Preface to the First Edition -- Nomenclature -- 1: Introduction -- References -- 2: Rates, Rate Constants, and Order -- I. Order -- II. Rates and Rate Constants -- 3: Active and Passive Transport -- I. Introduction -- II. Passive Transport -- III. Active Transport -- References -- 4: Pharmacokinetics -- I. Introduction -- II. Drug Disposition -- III. Constant-Rate Intravenous Infusion -- IV. Compartmental Models and Their Limitations -- V. Absorption Rate Constants -- References -- 5: Biopharmaccutics -- I. Extravascular Administration -- II. Absorption of Drugs from the Gastrointestinal Tract -- III. Factors Influencing Bioavailability -- IV. Evaluation of the Bioavailability of a Single Drug -- V. Drug Delivery to Prolong Duration -- References -- 6: Dosage Regimens -- I. Introduction -- II. Accumulation During Repetitive Dosing -- III. Adjustment of Dosage Regimen in Renal Failure -- IV. Multiple Dosing of Constant-Rate Intravenous Infusions -- References -- 7: Pharmacokinetic Aspects of Structural Modifications in Drug Design and Therapy -- I. Introduction -- II. Antimicrobial Agents -- III. Pharmacokinetics of Prodrugs -- IV. Stereoisomers -- References -- 8: Pharmacokinetic Applications in Clinical Practice -- I. Introduction -- II. Pharmacokinetic Drug Interactions -- III. Clinical Pharmacokinetics -- References -- Appendix -- Index
Author: Sara E. Rosenbaum
Publisher: John Wiley & Sons
ISBN: 1119143187
Category : Medical
Languages : en
Pages : 816
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Book Description
Updated with new chapters and topics, this book provides a comprehensive description of all essential topics in contemporary pharmacokinetics and pharmacodynamics. It also features interactive computer simulations for students to experiment and observe PK/PD models in action. • Presents the essentials of pharmacokinetics and pharmacodynamics in a clear and progressive manner • Helps students better appreciate important concepts and gain a greater understanding of the mechanism of action of drugs by reinforcing practical applications in both the book and the computer modules • Features interactive computer simulations, available online through a companion website at: https://web.uri.edu/pharmacy/research/rosenbaum/sims/ • Adds new chapters on physiologically based pharmacokinetic models, predicting drug-drug interactions, and pharmacogenetics while also strengthening original chapters to better prepare students for more advanced applications • Reviews of the 1st edition: “This is an ideal textbook for those starting out ... and also for use as a reference book ...." (International Society for the Study of Xenobiotics) and “I could recommend Rosenbaum’s book for pharmacology students because it is written from a perspective of drug action . . . Overall, this is a well-written introduction to PK/PD .... “ (British Toxicology Society Newsletter)
Author: Dr. A. R. Paradkar
Publisher: Pragati Books Pvt. Ltd.
ISBN: 9788185790374
Category :
Languages : en
Pages : 198
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Book Description
Author: J. S. Kulkarni
Publisher: CBS Publishers & Distributors Pvt Limited, India
ISBN: 9788123913070
Category : Medical
Languages : en
Pages : 301
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Book Description
Biopharmaceutics and Pharmacokinetics deals with what body does to the drug. In this book, along with the fundamentals of absorption, distribution, metabolism and excretion, current topics such as in vitro systems have also been introduced. In case of pharmacokinetics models, authors have tried to keep mathematical part simpler and minimal. This book also introduces "non compartmental models", which are gaining increasing importance in the analysis of pharmacokinetic data. In the chapter "applications of pharamacokinetics", newer concepts such as chronopharmacokinetics have been introduced. Bioequivalence is covered in last two chapters. Besides clinical aspects of bioequivalence, some of the important aspects of bioanalysis have also been introduced. The regulatory aspect of bioequivalence has also been covered. Thus an attempt has been made to cover all the basic aspects of biopharmaceutics and pharmacokinetics in a reader-friendly manner.
Author: A. Kar
Publisher: CBS Publishers & Distributors Pvt Limited, India
ISBN: 9789388327534
Category : Medical
Languages : en
Pages :
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Book Description
A comprehensive textbook for learning and teaching the fundamentals of biopharmaceutics along with specific focus on pharmacokinetics for BPharm and MPharm students.
Author: Leon Shargel
Publisher: McGraw Hill Professional
ISBN: 0071375503
Category : Medical
Languages : en
Pages : 915
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Book Description
The most comprehensive text on the practical applications of biopharmaceuticals and pharmacokinetics! 4 STAR DOODY'S REVIEW! "The updated edition provides the reader with a solid foundation in the basic principles of pharmacokinetics and biopharmaceutics. Students will be able to apply the information to their clinical practice and researchers will find this to be a valuable reference. This modestly priced book should be the gold standard for student use."--Doody's Review Service The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.
Author: Dr. Satyajit Panda, Dr. Chandra Sekhar Barik, Dr. Bhargab Jyoti Sahariah
Publisher: Shashwat Publication
ISBN: 9360877921
Category : Medical
Languages : en
Pages : 279
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Book Description
According to PCI regulations, the book is named "Textbook of Biopharmaceutics and Pharmacokinetics". The authors' original intention for the book was to provide a unified database that would make Biopharmaceutics and Pharmacokinetics easily understood. This book aims to enlighten readers on cutting-edge drug delivery methods and provide guidance to educators and students on the essential ideas of Biopharmaceutics and Pharmacokinetics. The primary goal in writing this textbook was to satisfy students' needs in accordance with PCI regulations by presenting material in an eloquent, summarised way. This book is intended to convey information on Biopharmaceutics and Pharmacokinetics to postgraduate learners, in addition to adhering to the curriculum of PCI's undergraduate pharmacy courses. We guarantee that this book will be highly appreciated by academics, professionals in the field, postgraduate students, and graduates. Nonetheless, recommendations about how to make the text better are welcome and will be duly noted.
Author: Mr. Mahaveer Singh, Dr. Ram Kumar Choudhary , Dr. Sandeep Kumar , Dr. Kuldeep Waidya , Dr. T. Sivakumar
Publisher: Shashwat Publication
ISBN: 9360876097
Category : Medical
Languages : en
Pages : 330
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Book Description
The titled book is “Textbook of BIOPHARMACEUTICS AND PHARMACOKINETICS” (As per PCI regulation). The idea of book originated by authors to convey a combined database for easy understanding of BIOPHARMACEUTICS AND PHARMACOKINETICS. This book is intended to communicate information on novel drug delivery techniques, to direct tutors and learners regarding fundamental concepts in biopharmaceutics. The major aim to write this textbook is to provide information in articulate summarized manner to accomplish necessities of undergraduates as per PCI regulation. This volume is designed not only according to curriculum of undergraduate courses in pharmacy by PCI but also to communicate knowledge on BIOPHARMACEUTICS AND PHARMACOKINETICS for post graduate learners. We assured this book will be originated very valuable by graduates, post graduates, professors and industrial learners.
Author: Younggil Kwon
Publisher: Springer Science & Business Media
ISBN: 0306468204
Category : Medical
Languages : en
Pages : 302
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Book Description
In the pharmaceutical industry, the incorporation of the disciplines of pharma- kinetics, pharmacodynamics, and drug metabolism (PK/PD/DM) into various drug development processes has been recognized to be extremely important for approp- ate compound selection and optimization. During discovery phases, the identifi- tion of the critical PK/PD/DM issues of new compounds plays an essential role in understanding their pharmacological profiles and structure-activity relationships. Owing to recent progress in analytical chemistry, a large number of compounds can be screened for their PK/PD/DM properties within a relatively short period of time. During development phases as well, the toxicology and clinical study designs and trials of a compound should be based on a thorough understanding of its PK/PD/DM properties. During my time as an industrial scientist, I realized that a reference work designed for practical industrial applications of PK/PD/DM could be a very valuable tool for researchers not only in the pharmacokinetics and drug metabolism departments, but also for other discovery and development groups in pharmaceutical companies. This book is designed specifically for industrial scientists, laboratory assistants, and managers who are involved in PK/PD/DM-related areas. It consists of thirteen chapters, each of which deals with a particular PK/PD/DM issue and its industrial applications. Chapters 3 and 12 in particular address recent topics on higher throughput in vivo exposure screening and the prediction of pharmacokinetics in humans, respectively. Chapter 8 covers essential information on drug metabolism for industrial scientists.
