Epidemiology of Alzheimer’s Disease: From Gene to Prevention PDF Download
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Author: Richard Mayeux
Publisher: Springer Science & Business Media
ISBN: 364260076X
Category : Medical
Languages : en
Pages : 140
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Book Description
This volume contains the proceedings of the 14th Colloque Médecine et Recherche of the Fondation Ipsen pour la Recherche Thérapeutique devoted to Alzheimer's Disease and dedicated to the epidemiological study of this dementia, a very important issue because the incidence and prevalence of Alzheimer's Disease rise exponentially with age. Epidemiological findings not only confirm dementia as a major challenge for the coming years but also contribute defining risk factors, predicting and may be preventing this disease.
Author: Richard Mayeux
Publisher: Springer Science & Business Media
ISBN: 364260076X
Category : Medical
Languages : en
Pages : 140
Get Book
Book Description
This volume contains the proceedings of the 14th Colloque Médecine et Recherche of the Fondation Ipsen pour la Recherche Thérapeutique devoted to Alzheimer's Disease and dedicated to the epidemiological study of this dementia, a very important issue because the incidence and prevalence of Alzheimer's Disease rise exponentially with age. Epidemiological findings not only confirm dementia as a major challenge for the coming years but also contribute defining risk factors, predicting and may be preventing this disease.
Author: Muin J. Khoury
Publisher: Oxford University Press
ISBN: 0195146743
Category : Medical
Languages : en
Pages : 571
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Book Description
This book describes the important role that epidemiologic methods play in the continuum from gene discovery to the development and application of genetic tests. It proceeds systematically from the fundamentals of genome technology and gene discovery, to epidemiologic approaches to gene characterization in the population, to the evaluation of genetic tests and their use in health services.
Author: Tiia Ngandu
Publisher: Elsevier Inc. Chapters
ISBN: 0128070366
Category : Medical
Languages : en
Pages : 432
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Book Description
Today there are more than 36 million demented persons worldwide. With the aging of populations, the prevalence of dementia and Alzheimer’s disease (AD) is expected to more than triple in the coming 40 years. Besides high age and genetic factors, evidence from observational studies shows that many modifiable vascular and lifestyle-related risk factors at midlife affect the risk of the disease. Control of vascular and metabolic risk factors, healthy diet, and maintenance of AN active lifestyle (physical, mental, and social components) may thus be the key issues on the road to prevent or delay the onset of AD. As the pathologic processes leading to AD may take decades to develop, it is crucial to identify optimal time windows for preventive efforts. Targeting several risk factors simultaneously and long duration of the intervention may be needed for the optimal preventive effect. As many persons are affected, relatively small effects of an integrative intervention on common risk factors may have a huge public health impact. Usage of biomarkers may help in identifying different risk phenotypes and in monitoring effects of the interventions. International collaboration is necessary to initiate future large-scale dementia prevention studies that are needed to formulate evidence-based preventive measures in cognitive decline and dementia.
Author: George J. Brewer
Publisher: Academic Press
ISBN: 0128111631
Category : Medical
Languages : en
Pages : 154
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Book Description
Environmental Causes and Prevention Measures for Alzheimer’s Disease examines the increased incidence of the disease in developed countries and aims to educate neuroscientists, medical practitioners and other educated individuals on new insights into environmental causation, primarily metals. This book looks into the web of evidence around the hypothesis of copper toxicity and the additional role that a high fat diet plays in disease progression and cognition loss. The data and its implications are discussed, along with potential prevention measures. This book will generate excitement and interest among neuroscientists, medical practitioners and other biomedical researchers. Emphasizes the history and epidemiology of Alzheimer’s disease, highlighting its epidemic proportions in developed countries Discusses data on new environmental factors in developed countries Provides prevention measures to potentially reduce Alzheimer’s rates through diet
Author: Amy Borenstein
Publisher: Academic Press
ISBN: 0124171540
Category : Psychology
Languages : en
Pages : 466
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Book Description
Alzheimer's Disease: Lifecourse Perspectives on Risk Reduction summarizes the growing body of knowledge on the distribution and causes of Alzheimer’s disease (AD) in human populations, providing the reader with knowledge on how we define the disease and what its risk and protective factors are in the context of a life-course approach. At the conclusion of the book, the reader will understand why Alzheimer’s disease likely begins at conception, then progresses through early-life and adult risk factors that ultimately impact the balance between pathologic insults in the brain and the ability of the brain to modify disease symptoms. In contrast to edited volumes that may have little cohesion, this book focuses on an integrated life-course approach to the epidemiology of dementia, in particular, Alzheimer’s disease. Reviews the current science surrounding Alzheimer’s disease Provides a primer of foundational knowledge on the disease's epidemiology and biostatistics Utilizes a life-course approach, providing a novel and integrated view of the evolution of this illness from genes to brain reserve Uses the ‘threshold model’—a theory first described by Dr. Mortimer and widely accepted today—which incorporates the idea of risk factors for the pathology and expression of the disease Proposes that improving brain health through modifiable behaviors can delay disease onset until a later age Examines the future of prevention of Alzheimer’s disease, a subject of great current interest
Author: Anthony F. Jorm
Publisher: Van Nostrand Reinhold Company
ISBN: 9780442313159
Category :
Languages : en
Pages : 234
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Book Description
Author: Zaven S Khachaturian
Publisher: CRC Press
ISBN: 042953597X
Category : Medical
Languages : en
Pages : 579
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Book Description
Published in 1996: Alzheimer's disease is characterized by memory disturbances and changes in personality and is associated with aging, although it can occur in people under 65. It is a progressive disease, painful to witness as the patient's health declines. Alzheimer's Disease: Cause(s), Diagnosis, and Care, with its complete and authoritative discussions, will help you understand all facets of this complex disease. This book addresses a broad spectrum of topics ranging from diagnosis, causes, treatment, epidemiology, genetics, risk factors, and care and management. Alzheimer's Disease: Cause(s), Diagnosis, and Care is intended for a diverse audience, including practitioners and students, family members, and everyone who is concerned about this disease.
Author: Jack C. de la Torre
Publisher: Springer
ISBN: 3319340573
Category : Medical
Languages : en
Pages : 256
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Book Description
This compelling text provides an overview of the available technology for early detection and therapeutic management of vascular risk factors to Alzheimer’s before severe cognitive impairment symptoms appear. Chapters bring the reader from the trackless clinical research that has characterized Alzheimer’s progress for the last 20 years, to a nexus of new ideas and concepts that can change our outlook of this dementia. In-depth examinations of various hypotheses, preventive measures, current and prospective treatments are openly and clearly explored. The author discusses in depth his proposal of the vascular hypothesis of Alzheimer's disease which has become a mother-lode for basic and clinical studies and a key approach to the prevention of this dementia.Alzheimer’s Turning Point offers professionals, students and those looking to learn more about this disorder a fresh clinical perspective of this devastating disease.
Author: Konrad Maurer
Publisher: Springer Science & Business Media
ISBN: 3709133963
Category : Medical
Languages : en
Pages : 585
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Book Description
The book Alzheimer's Disease - Epidemiology, Neuropathology, Neurochemistry, and Clinics is derived from an International Symposium on the occasion of the 125th Anniversary of the Birth of Alois Alzheimer (14.6.1864-19.12.1915). Over the past decade, as the elderly have become the fastest-growing segment of the population in industrialized countries, Alzheimer's disease has emerged as one of the major mental health problems. The contributors to this book represent internationally recognized authorities in the field of dementia and present new information about epidemiology, neuropathology, neurochemistry, and clinics in Alzheimer's disease. This book is a rich and valuable up-to-date resource for psychiatrists, neurologists, scientists working in the fields of neuropathology, neurochemistry and molecular genetics, behavioral scientists, family physicians and all who share an interest in understanding and treating the older individual with Alzheimer's disease/dementia.
Author: Taher Zandi
Publisher: Springer Science & Business Media
ISBN: 1461306655
Category : Medical
Languages : en
Pages : 165
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Book Description
The management of Alzheimer's Disease and the related dementias is one of the major challenges to health care professionals and American society-at-large for the coming decade and the coming millennium. The rapid growth of the over-eighty-five population, the group which, as recent studies have confirmed and as many of us clinicians have long suspected, has an even higher prevalence than previously quoted of dementing disorders, is the major cause of this. We are thus challenged by, as Bernard Issacs used to call it, "the survival of the unfittest," as well as the oPtimistic approach of "bringing life to years," as John F. Kennedy said. The fact is that we, as a society, tend to confuse "treatment" and "cure" (and "prevention"). As the proceedings of the conference which this book represents emphasize, there is considerable work going on about the potential prevention of, or at least the reduction of, symptomatology in these illnesses by interventions genetically, chemIcally, and so forth. However, the more we find out, the more complicated it becomes, and the more heterogeneous Alzheimer's and the related disorders appear to be, not only in their manifestations (as clinicians have long recognized) but also in the individual initiating and underlying processes. For these reasons, absolute preventive techniques or the likelihood of an intervention which will reverse the process in a high proportion of patients, do not appear to be just around the corner.
