Author: Daniela Cardinale
Publisher: CRC Press
ISBN: 9814613436
Category : Medical
Languages : en
Pages : 258
Book Description
Enzyme immobilization on solid supports has been considered for a long time as an attractive solution to perform sophisticated organic synthesis, which is required in the preparation of fine pharmaceutical chemicals. But in the late 1990s, the tremendous progress in molecular biology fundamentals opened up the possibility of feeding a toolbox for b
Enzyme Nanocarriers
Author: Daniela Cardinale
Publisher: CRC Press
ISBN: 9814613436
Category : Medical
Languages : en
Pages : 258
Book Description
Enzyme immobilization on solid supports has been considered for a long time as an attractive solution to perform sophisticated organic synthesis, which is required in the preparation of fine pharmaceutical chemicals. But in the late 1990s, the tremendous progress in molecular biology fundamentals opened up the possibility of feeding a toolbox for b
Publisher: CRC Press
ISBN: 9814613436
Category : Medical
Languages : en
Pages : 258
Book Description
Enzyme immobilization on solid supports has been considered for a long time as an attractive solution to perform sophisticated organic synthesis, which is required in the preparation of fine pharmaceutical chemicals. But in the late 1990s, the tremendous progress in molecular biology fundamentals opened up the possibility of feeding a toolbox for b
Introduction to Enzyme Technology
Author: Karl-Erich Jaeger
Publisher: Springer Nature
ISBN: 3031429990
Category :
Languages : en
Pages : 467
Book Description
Publisher: Springer Nature
ISBN: 3031429990
Category :
Languages : en
Pages : 467
Book Description
Nanoconjugate Nanocarriers for Drug Delivery
Author: Raj K. Keservani
Publisher: CRC Press
ISBN: 135117102X
Category : Medical
Languages : en
Pages : 453
Book Description
This new volume presents a plethora of new research on the use of nanoconjugate nanocarriers in drug delivery. Nanotechnology as drug carriers has been observed to increase the level of sophistication through a variety of ways. It helps to alleviate some of the pitfalls of conventional dosage forms, such as few pitfalls such as non-specific drug delivery, dose dumping, poor patient compliance, toxicities linked with higher doses, etc. With chapters from highly skilled, experienced, and renowned scientists and researchers, Nanoconjugate Nanocarriers for Drug Delivery is divided into four sections, providing an introduction to nanocarriers for drug delivery, physicochemical features of nanocarriers, and specific applications dealing with drug delivery in particular. The materials used as well as formulation and characterization have been discussed in detail. The nanocarriers covered in the book include nanoparticles, vesicular carriers, carriers having carbon as the core constituent, dispersed systems, etc. The book also delves into the interaction and associations between drug delivery research and its therapeutic applications in practice. The book integrates a wide variety of case studies, research, and theories in an attempt to reveal the diversity and capture the novel approaches of nanoconjugate nanocarriers for drug delivery employed by developers and content experts in the field. This timely publication will be an essential reference and current awareness source, building on the available literature in the field of pharmacy and biomedical science, while also providing ideas for further research opportunities in this dynamic field.
Publisher: CRC Press
ISBN: 135117102X
Category : Medical
Languages : en
Pages : 453
Book Description
This new volume presents a plethora of new research on the use of nanoconjugate nanocarriers in drug delivery. Nanotechnology as drug carriers has been observed to increase the level of sophistication through a variety of ways. It helps to alleviate some of the pitfalls of conventional dosage forms, such as few pitfalls such as non-specific drug delivery, dose dumping, poor patient compliance, toxicities linked with higher doses, etc. With chapters from highly skilled, experienced, and renowned scientists and researchers, Nanoconjugate Nanocarriers for Drug Delivery is divided into four sections, providing an introduction to nanocarriers for drug delivery, physicochemical features of nanocarriers, and specific applications dealing with drug delivery in particular. The materials used as well as formulation and characterization have been discussed in detail. The nanocarriers covered in the book include nanoparticles, vesicular carriers, carriers having carbon as the core constituent, dispersed systems, etc. The book also delves into the interaction and associations between drug delivery research and its therapeutic applications in practice. The book integrates a wide variety of case studies, research, and theories in an attempt to reveal the diversity and capture the novel approaches of nanoconjugate nanocarriers for drug delivery employed by developers and content experts in the field. This timely publication will be an essential reference and current awareness source, building on the available literature in the field of pharmacy and biomedical science, while also providing ideas for further research opportunities in this dynamic field.
Stimuli-Responsive Nanocarriers
Author: Virendra Gajbhiye
Publisher: Academic Press
ISBN: 0323859046
Category : Medical
Languages : en
Pages : 485
Book Description
Stimuli-Responsive Nanocarriers: Recent Advances in Tailor-Made Therapeutics compiles dispersed knowledge into a complete and comprehensive source to help researchers understand and progress stimuli-responsive nanocarriers. The book contains recent advancements made in the field of stimuli-responsive nanocarriers with their application in controlled drug delivery against various diseases. It focuses on the design, mechanism, construction, therapeutic application and future challenges of stimuli-responsive nanocarriers which will help new researchers in designing next generation tailor-made advanced therapeutics. Finally, the book covers future aspects and challenges present in the route of development of stimuli responsive nanocarriers for disease therapeutics. Various recent advances and biomedical applications assembled in this book will guide scientists on how to design and develop novel controlled drug release systems. - Provides comprehensive knowledge of basic design, mechanism and construction of nanocarrier based stimuli-responsive drug releases - Explores various nanocarriers characteristically used in the development of stimuli-responsive drug release systems - Envisages future opportunities, challenges and implementation of nanocarrier based stimuli-responsive drug release systems in disease therapeutics
Publisher: Academic Press
ISBN: 0323859046
Category : Medical
Languages : en
Pages : 485
Book Description
Stimuli-Responsive Nanocarriers: Recent Advances in Tailor-Made Therapeutics compiles dispersed knowledge into a complete and comprehensive source to help researchers understand and progress stimuli-responsive nanocarriers. The book contains recent advancements made in the field of stimuli-responsive nanocarriers with their application in controlled drug delivery against various diseases. It focuses on the design, mechanism, construction, therapeutic application and future challenges of stimuli-responsive nanocarriers which will help new researchers in designing next generation tailor-made advanced therapeutics. Finally, the book covers future aspects and challenges present in the route of development of stimuli responsive nanocarriers for disease therapeutics. Various recent advances and biomedical applications assembled in this book will guide scientists on how to design and develop novel controlled drug release systems. - Provides comprehensive knowledge of basic design, mechanism and construction of nanocarrier based stimuli-responsive drug releases - Explores various nanocarriers characteristically used in the development of stimuli-responsive drug release systems - Envisages future opportunities, challenges and implementation of nanocarrier based stimuli-responsive drug release systems in disease therapeutics
Nanomaterial-Supported Enzymes
Author: Inamuddin
Publisher: Materials Research Forum LLC
ISBN: 1644901978
Category : Technology & Engineering
Languages : en
Pages : 270
Book Description
The book presents recent advances in the field of nanoenzymes and the immobilization of enzymes in nanomaterials. Applications include disease diagnosis, environmental clean-up, biosensor manufacturing, drug delivery and vaccine production. Keywords: Nanoenzymes, Metal and Metal Oxide Nanoparticles, Carbon Nanotubes, Graphene, Activated Carbon, Enzyme Immobilization, Catalytic Activity, Leaching of the Enzyme, Enzyme Mimicking, Biosensors, Biosensing Mechanisms, Therapeutic Applications, Vассine Prоduсtiоn аnd Immunizаtiоn. Drug Delivery, Delivery of Vaccine Antigens, Antigen Resistance, Immunogenicity, Disease Diagnosis.
Publisher: Materials Research Forum LLC
ISBN: 1644901978
Category : Technology & Engineering
Languages : en
Pages : 270
Book Description
The book presents recent advances in the field of nanoenzymes and the immobilization of enzymes in nanomaterials. Applications include disease diagnosis, environmental clean-up, biosensor manufacturing, drug delivery and vaccine production. Keywords: Nanoenzymes, Metal and Metal Oxide Nanoparticles, Carbon Nanotubes, Graphene, Activated Carbon, Enzyme Immobilization, Catalytic Activity, Leaching of the Enzyme, Enzyme Mimicking, Biosensors, Biosensing Mechanisms, Therapeutic Applications, Vассine Prоduсtiоn аnd Immunizаtiоn. Drug Delivery, Delivery of Vaccine Antigens, Antigen Resistance, Immunogenicity, Disease Diagnosis.
Stimuli-Responsive Nanocarriers for Targeted Drug Delivery
Author: Muhammad Raza Shah
Publisher: Elsevier
ISBN: 0443223882
Category : Technology & Engineering
Languages : en
Pages : 396
Book Description
Stimuli-Responsive Nanocarriers for Targeted Drug Delivery presents a comprehensive overview of the most significant physical and chemical stimuli-responsive drug delivery systems. This book reviews targeted and controlled drug delivery systems and how nanocarriers can be used to improve the pharmacokinetics of drugs in biological systems, such as increasing utilization rate and reducing toxicity and side effects. After a key introduction to the topic, a range of nanocarrier types is assessed before exploring the clinical translation challenges and considerations involved.This book is a useful resource for researchers and postgraduate students in the fields of materials science, nanotechnology, pharmaceutical science, and medicinal chemistry. - Offers an in-depth look at the basic and fundamental aspects of stimuli-responsive materials, mechanisms, structure, synthesis and properties - Provides information about well-defined categorization for stimuli-responsive drug delivery system based on different triggering mechanisms to its reader - Reviews basic concepts and the latest research involving advances in stimuli-responsive drug delivery systems in controlled-release drugs - Discusses novel approaches and challenges for scaling-up and commercialization of stimuli-responsive polymers
Publisher: Elsevier
ISBN: 0443223882
Category : Technology & Engineering
Languages : en
Pages : 396
Book Description
Stimuli-Responsive Nanocarriers for Targeted Drug Delivery presents a comprehensive overview of the most significant physical and chemical stimuli-responsive drug delivery systems. This book reviews targeted and controlled drug delivery systems and how nanocarriers can be used to improve the pharmacokinetics of drugs in biological systems, such as increasing utilization rate and reducing toxicity and side effects. After a key introduction to the topic, a range of nanocarrier types is assessed before exploring the clinical translation challenges and considerations involved.This book is a useful resource for researchers and postgraduate students in the fields of materials science, nanotechnology, pharmaceutical science, and medicinal chemistry. - Offers an in-depth look at the basic and fundamental aspects of stimuli-responsive materials, mechanisms, structure, synthesis and properties - Provides information about well-defined categorization for stimuli-responsive drug delivery system based on different triggering mechanisms to its reader - Reviews basic concepts and the latest research involving advances in stimuli-responsive drug delivery systems in controlled-release drugs - Discusses novel approaches and challenges for scaling-up and commercialization of stimuli-responsive polymers
Nano-Enzyme Incorporated Particles
Author: Veleeswaran Ananthi
Publisher: Elsevier
ISBN: 0443188114
Category : Science
Languages : en
Pages : 352
Book Description
Approx.296 pages - Focuses on integrative approaches of the enzyme nanoparticle synthesis and its applications on biomedicine, biosensors, and biocatalysis - Encloses the potential challenges and developments of enzyme incorporated nanoparticles - Discusses the vital activities of nanozymes in enzyme mimicking processes and prudent bio-catalytic efficiency - Covers the latest methods and procedures involved in enzyme-incorporated nanomaterials
Publisher: Elsevier
ISBN: 0443188114
Category : Science
Languages : en
Pages : 352
Book Description
Approx.296 pages - Focuses on integrative approaches of the enzyme nanoparticle synthesis and its applications on biomedicine, biosensors, and biocatalysis - Encloses the potential challenges and developments of enzyme incorporated nanoparticles - Discusses the vital activities of nanozymes in enzyme mimicking processes and prudent bio-catalytic efficiency - Covers the latest methods and procedures involved in enzyme-incorporated nanomaterials
Phospholipases in Physiology and Pathology
Author: Sajal Chakraborti
Publisher: Elsevier
ISBN: 0323956882
Category : Science
Languages : en
Pages : 2974
Book Description
Phospholipases in Physiology and Pathology presents a comprehensive overview on the physiology and pathology of phospholipases. This seven-volume set considers the biochemical and molecular mechanisms of normal and abnormal cell function upon dysregulation of phospholipases in different diseases. Volumes cover signal transduction mechanisms, implications in cancer, infectious diseases, neural diseases, cardiovascular diseases and other diseases, implications in inflammation, apoptosis, gene expression and non-coding RNAs, the role of natural and synthetic compounds, and stem cell therapies, nanotechnology-based therapies, and more. Together, these volumes give researchers critical insight on the mechanistic and therapeutic aspects of phospholipases. - Discusses the biochemical and molecular mechanisms of normal and abnormal cell function in different disease processes - Covers a wide range of basic and translational research appropriate for scientists engaged in studying the regulation of phospholipases from interdisciplinary perspectives - Features state-of-the-art chapter contributions from international leaders in the field
Publisher: Elsevier
ISBN: 0323956882
Category : Science
Languages : en
Pages : 2974
Book Description
Phospholipases in Physiology and Pathology presents a comprehensive overview on the physiology and pathology of phospholipases. This seven-volume set considers the biochemical and molecular mechanisms of normal and abnormal cell function upon dysregulation of phospholipases in different diseases. Volumes cover signal transduction mechanisms, implications in cancer, infectious diseases, neural diseases, cardiovascular diseases and other diseases, implications in inflammation, apoptosis, gene expression and non-coding RNAs, the role of natural and synthetic compounds, and stem cell therapies, nanotechnology-based therapies, and more. Together, these volumes give researchers critical insight on the mechanistic and therapeutic aspects of phospholipases. - Discusses the biochemical and molecular mechanisms of normal and abnormal cell function in different disease processes - Covers a wide range of basic and translational research appropriate for scientists engaged in studying the regulation of phospholipases from interdisciplinary perspectives - Features state-of-the-art chapter contributions from international leaders in the field
Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy
Author: Muhammad Raza Shah
Publisher: Elsevier
ISBN: 0128163119
Category : Technology & Engineering
Languages : en
Pages : 312
Book Description
Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy reviews the principles and applications of nanocarriers for targeted drug delivery. Drug targeting involves active and passive strategies that exploit both the use of ligands for interactions and the physical and chemical properties of nanocarriers and micro-environments at target sites. Multidrug resistance and adverse side effects associated with anticancer drugs have attracted greater scientific attention and led formulation scientists to specifically target these drugs to target sites. Nanocarriers like liposomes, niosomes, gold nanorods, carbon nanotubes, and micelles are discussed for the delivery of drugs to specific disease sites. This is an important reference source for researchers in the biomedical and biomaterials fields who want to gain an understanding on how nanotechnology is used for earlier diagnoses and more effective cancer treatment. - Explores the fundamental principles of drug targeting through different nano-carriers, highlighting major applications - Shows how the use of nanocarriers is leading to quicker cancer diagnosis and more effective treatment - Discusses the major challenges of using nanocarriers for drug delivery and assesses how to overcome these barriers
Publisher: Elsevier
ISBN: 0128163119
Category : Technology & Engineering
Languages : en
Pages : 312
Book Description
Nanocarriers for Cancer Diagnosis and Targeted Chemotherapy reviews the principles and applications of nanocarriers for targeted drug delivery. Drug targeting involves active and passive strategies that exploit both the use of ligands for interactions and the physical and chemical properties of nanocarriers and micro-environments at target sites. Multidrug resistance and adverse side effects associated with anticancer drugs have attracted greater scientific attention and led formulation scientists to specifically target these drugs to target sites. Nanocarriers like liposomes, niosomes, gold nanorods, carbon nanotubes, and micelles are discussed for the delivery of drugs to specific disease sites. This is an important reference source for researchers in the biomedical and biomaterials fields who want to gain an understanding on how nanotechnology is used for earlier diagnoses and more effective cancer treatment. - Explores the fundamental principles of drug targeting through different nano-carriers, highlighting major applications - Shows how the use of nanocarriers is leading to quicker cancer diagnosis and more effective treatment - Discusses the major challenges of using nanocarriers for drug delivery and assesses how to overcome these barriers
Smart Internal Stimulus-Responsive Nanocarriers for Drug and Gene Delivery
Author: Mahdi Karimi
Publisher: Morgan & Claypool Publishers
ISBN: 1681742586
Category : Science
Languages : en
Pages : 98
Book Description
The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo. This can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to internal stimuli that are intrinsic to the target site. These stimuli are specific to the cell type, tissue or organ type, or to the disease state (cancer, infection, inflammation etc). pH-responsive nanostructures can be used for cargo release in acidic endosomal compartments, in the lower pH of tumors, and for specific oral delivery either to the stomach or intestine. Nanocarriers can be designed to be substrates of a wide-range of enzymes that are over-expressed at disease sites. Oxidation and reduction reactions can be taken advantage of in smart nanocarriers by judicious molecular design. Likewise, nanocarriers can be designed to respond to a range of specific biomolecules that may occur at the target site. In this volume we also cover dual and multi-responsive systems that combine stimuli that could be either internal or external.
Publisher: Morgan & Claypool Publishers
ISBN: 1681742586
Category : Science
Languages : en
Pages : 98
Book Description
The concept of smart drug delivery vehicles involves designing and preparing a nanostructure (or microstructure) that can be loaded with a cargo. This can be a therapeutic drug, a contrast agent for imaging, or a nucleic acid for gene therapy. The nanocarrier serves to protect the cargo from degradation by enzymes in the body, to enhance the solubility of insoluble drugs, to extend the circulation half-life, and to enhance its penetration and accumulation at the target site. Importantly, smart nanocarriers can be designed to be responsive to a specific stimulus, so that the cargo is only released or activated when desired. In this volume we cover smart nanocarriers that respond to internal stimuli that are intrinsic to the target site. These stimuli are specific to the cell type, tissue or organ type, or to the disease state (cancer, infection, inflammation etc). pH-responsive nanostructures can be used for cargo release in acidic endosomal compartments, in the lower pH of tumors, and for specific oral delivery either to the stomach or intestine. Nanocarriers can be designed to be substrates of a wide-range of enzymes that are over-expressed at disease sites. Oxidation and reduction reactions can be taken advantage of in smart nanocarriers by judicious molecular design. Likewise, nanocarriers can be designed to respond to a range of specific biomolecules that may occur at the target site. In this volume we also cover dual and multi-responsive systems that combine stimuli that could be either internal or external.