Author: Dietmar Schomburg
Publisher:
ISBN: 9780387564357
Category : Electronic books
Languages : en
Pages : 982
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Book Description
Includes nomenclature, reactions and specificity, enzyme structure, isolation / preparation, stability, cross references to structure databanks, and literature references for each enzyme.
Author: Dietmar Schomburg
Publisher: Springer Science & Business Media
ISBN: 3642852009
Category : Science
Languages : en
Pages : 624
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Book Description
Recent progress on enzyme immobilisation, enzyme production, coenzyme re generation and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. As more progress in research and application of enzymes has been made the lack of an up-to-date overview of enzyme molecular properties has become more appar ent. Therefore, we started the development of an enzyme data information sys tem as part of protein-design activities at GBF. The present book "Enzyme Hand book" represents the printed version of this data bank. In future a computer searchable version will be also available. The enzymes in this Handbook are arranged according to the Enzyme Com mission list of enzymes. Some 3000 "different" enzymes will be covered. Fre quently enzymes with very different properties are included under the same EC number. Although we intend to give a representative overview on the char acteristics and variability of each enzyme the Handbook is not a compendium. The reader will have to go to the primary literature for more detailed information. Naturally it is not possible to cover all the numerous literature references tor each enzyme (for special enzymes up to 40000) if the data representation is to be concise as is intended.
Author: Dietmar Schomburg
Publisher: Springer Science & Business Media
ISBN: 3642362656
Category : Science
Languages : en
Pages : 736
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Book Description
Springer Handbook of Enzymes provides data on enzymes sufficiently well characterized. It offers concise and complete descriptions of some 5,000 enzymes and their application areas. Data sheets are arranged in their EC-Number sequence and the volumes themselves are arranged according to enzyme classes. This new, second edition reflects considerable progress in enzymology: many enzymes are newly classified or reclassified. Each entry is correlated with references and one or more source organisms. New datafields are created: application and engineering (for the properties of enzymes where the sequence has been changed). The total amount of material contained in the Handbook has more than doubled so that the complete second edition consists of 39 volumes as well as a Synonym Index. In addition, starting in 2009, all newly classified enzymes are treated in Supplement Volumes. Springer Handbook of Enzymes is an ideal source of information for researchers in biochemistry, biotechnology, organic and analytical chemistry, and food sciences, as well as for medicinal applications.
Author: Dietmar Schomburg
Publisher: Springer
ISBN: 3642580513
Category : Science
Languages : en
Pages : 822
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Book Description
The objective of the Enzyme Handbook is to provide in a concise form data on enzymes sufficiently well characterized. Data of about 3000 enzymes are presently known and their data sheets will be published at a frequency of 200 per quarter. The data sheets are arranged in their EC Number sequence, Vol. 6 containing Oxidoreductases (Class 1.2: Acting on aldehyde or keto-group of donors, Class 1.3: Acting on CH-CH group of donors, Class 1.4: Acting on CH-NH2 group of donors). For each enzyme, systematic and common names are given, information on reaction type, substrate and product spectrum, inhibitors, cofactors, kinetic data, pH and temperature range, origin, purification, molecular data and storage conditions are listed. A reference list completes the data sheet. This collection is an indispensable source of information for researchers applying enzymes in analysis, synthesis and biotechnology.
Author: Dietmar Schomburg
Publisher: Springer Science & Business Media
ISBN: 3642785212
Category : Science
Languages : en
Pages : 743
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Book Description
Recent progress on enzyme immobilisation, enzyme production, coenzyme regeneration and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. As more progress in research and application of enzymes has been made the lack of an up-to-date overview of enzyme molecular properties has become more apparent. Therefore, we started the development of an enzyme data in formation system as part of protein-design activities at GBF. The present book" Enzyme Handbook" represents the printed version of this data bank. In future a computer searchable version will be also available. The enzymes in this Handbook are arranged according to the Enzyme Commission list of enzymes. Some 3000 "different" enzymes will be covered. Frequently enzymes with very different properties are included under the same EC number. Although we intend to give a representative overview on the characteristics and variability of each enzyme the Handbook is not a com pendium. The reader will have to go to the primary literature for more detailed information. Naturally it is not possible to cover all the numerous literature references for each enzyme (for special enzymes up to 40000) if the data re presentation is to be concise as is intended.
Author: Dietmar Schomburg
Publisher: Springer Science & Business Media
ISBN: 3642577563
Category : Science
Languages : en
Pages : 622
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Book Description
Recent progress on enzyme immobilisation, enzyme production, coenzyme re generation and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. As more progress in research and application of enzymes has been made the lack of an up-to-date overview of enzyme molecular properties has become more appar ent. Therefore, we started the development of an enzyme data information sys tem as part of protein-design activities at GBF. The present book "Enzyme Hand book" represents the printed version of this data bank. In future a computer searchable version will be also available. The enzymes in this Handbook are arranged according to the Enzyme Com mission list of enzymes. Some 3000 "different" enzymes will be covered. Fre quently enzymes with very different properties are included under the same EC number. Although we intend to give a representative overview on the char acteristics and variability of each enzyme the Handbook is not a compendium. The reader will have to go to the primary literature for more detailed information. Naturally it is not possible to cover all the numerous literature references for each enzyme (for special enzymes up to 40000) if the data representation is to be concise as is intended.
Author: Dietmar Schomburg
Publisher: Springer Science & Business Media
ISBN: 3642589693
Category : Science
Languages : en
Pages : 304
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Book Description
Today, as the large international genome sequence projects are gaining a great amount of public attention and huge sequence data bases are created it be comes more and more obvious that we are very limited in our ability to access functional data for the gene products - the proteins, in particular for enzymes. Those data are inherently very difficult to collect, interpret and standardize as they are highly distributed among journals from different fields and are often sub ject to experimental conditions. Nevertheless a systematic collection is essential for our interpretation of the genome information and more so for possible appli cations of this knowledge in the fields of medicine, agriculture, etc .. Recent pro gress on enzyme immobilization, enzyme production, enzyme inhibition, coen zyme regeneration and enzyme engineering has opened up fascinating new fields for the potential application of enzymes in a large range of different areas. It is the functional profile of an enzyme that enables a biologist or physician to analyse a metabolic pathway and its disturbance; it is the substrate specificity of an enzyme which tells an analytical biochemist how to design an assay; it is the stability, specificity and efficiency of an enzyme which determines its usefulness in the biotechnical transformation of a molecule. And the sum of all these data will have to be considered when the designer of artificial biocatalysts has to choose the optimum prototype to start with.
Author: Dietmar Schomburg
Publisher: Springer Science & Business Media
ISBN: 3642589030
Category : Science
Languages : en
Pages : 675
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Book Description
The objective of the Enzyme Handbook is to provide in concise form data on enzymes sufficiently well characterized. The data sheets are arranged in their EC number sequence, volumes 15 to 17 contain Additional Enzymes and updated data sheets to be inserted in previous volumes by their EC-number. For each enzyme, systematic and common names are given, information on reaction type, substrate and product spectrum, inhibitors, cofactors, kinetic data, pH and temperature range, origin, purification, molecular data and storage conditions are listed. A reference list completes the data sheets. This collection is an indispensable source of information for researchers applying enzymes in analysis, synthe.
Author: James A. Kent
Publisher: Springer Science & Business Media
ISBN: 1461442591
Category : Science
Languages : en
Pages : 1560
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Book Description
Substantially revising and updating the classic reference in the field, this handbook offers a valuable overview and myriad details on current chemical processes, products, and practices. No other source offers as much data on the chemistry, engineering, economics, and infrastructure of the industry. The Handbook serves a spectrum of individuals, from those who are directly involved in the chemical industry to others in related industries and activities. It provides not only the underlying science and technology for important industry sectors, but also broad coverage of critical supporting topics. Industrial processes and products can be much enhanced through observing the tenets and applying the methodologies found in chapters on Green Engineering and Chemistry (specifically, biomass conversion), Practical Catalysis, and Environmental Measurements; as well as expanded treatment of Safety, chemistry plant security, and Emergency Preparedness. Understanding these factors allows them to be part of the total process and helps achieve optimum results in, for example, process development, review, and modification. Important topics in the energy field, namely nuclear, coal, natural gas, and petroleum, are covered in individual chapters. Other new chapters include energy conversion, energy storage, emerging nanoscience and technology. Updated sections include more material on biomass conversion, as well as three chapters covering biotechnology topics, namely, Industrial Biotechnology, Industrial Enzymes, and Industrial Production of Therapeutic Proteins.
Author: Perry A. Frey
Publisher: Oxford University Press
ISBN: 0199880743
Category : Science
Languages : en
Pages : 1095
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Book Description
Books dealing with the mechanisms of enzymatic reactions were written a generation ago. They included volumes entitled Bioorganic Mechanisms, I and II by T.C. Bruice and S.J. Benkovic, published in 1965, the volume entitled Catalysis in Chemistry and Enzymology by W.P. Jencks in 1969, and the volume entitled Enzymatic Reaction Mechanisms by C.T. Walsh in 1979. The Walsh book was based on the course taught by W.P. Jencks and R.H. Abeles at Brandeis University in the 1960's and 1970's. By the late 1970's, much more could be included about the structures of enzymes and the kinetics and mechanisms of enzymatic reactions themselves, and less emphasis was placed on chemical models. Walshs book was widely used in courses on enzymatic mechanisms for many years. Much has happened in the field of mechanistic enzymology in the past 15 to 20 years. Walshs book is both out-of-date and out-of-focus in todays world of enzymatic mechanisms. There is no longer a single volume or a small collection of volumes to which students can be directed to obtain a clear understanding of the state of knowledge regarding the chemicals mechanisms by which enzymes catalyze biological reactions. There is no single volume to which medicinal chemists and biotechnologists can refer on the subject of enzymatic mechanisms. Practitioners in the field have recognized a need for a new book on enzymatic mechanisms for more than ten years, and several, including Walsh, have considered undertaking to modernize Walshs book. However, these good intentions have been abandoned for one reason or another. The great size of the knowledge base in mechanistic enzymology has been a deterrent. It seems too large a subject for a single author, and it is difficult for several authors to coordinate their work to mutual satisfaction. This text by Perry A. Frey and Adrian D. Hegeman accomplishes this feat, producing the long-awaited replacement for Walshs classic text.
