Endocrinopathy After Childhood Cancer Treatment PDF Download
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Author: W. H. B. Wallace
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805590377
Category : Medical
Languages : en
Pages : 197
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Book Description
Continuing advances in the management of childhood malignancies result in a rapidly growing number of childhood cancer survivors. However, many of them experience treatment-induced 'late effects' including a significant number of endocrine dysfunctions.In this book experts in the field of late effects of childhood cancer treatment offer clinical insight into pertinent issues such as the impact of cancer therapies on growth, puberty and hypothalamic and pituitary function, male and female fertility, obesity, and metabolic and bone problems.Multidisciplinary long-term follow-up of these patients is essential to monitor, treat and prevent morbidity. Therefore this volume is of great interest to pediatric endocrinologists and oncologists, adult and reproductive endocrinologists, primary care practitioners, nurses and nurse practitioners as well as others involved in planning and delivering the holistic care which this increasingly numerous and important group of patients requires.
Author: W. H. B. Wallace
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805590377
Category : Medical
Languages : en
Pages : 197
Get Book
Book Description
Continuing advances in the management of childhood malignancies result in a rapidly growing number of childhood cancer survivors. However, many of them experience treatment-induced 'late effects' including a significant number of endocrine dysfunctions.In this book experts in the field of late effects of childhood cancer treatment offer clinical insight into pertinent issues such as the impact of cancer therapies on growth, puberty and hypothalamic and pituitary function, male and female fertility, obesity, and metabolic and bone problems.Multidisciplinary long-term follow-up of these patients is essential to monitor, treat and prevent morbidity. Therefore this volume is of great interest to pediatric endocrinologists and oncologists, adult and reproductive endocrinologists, primary care practitioners, nurses and nurse practitioners as well as others involved in planning and delivering the holistic care which this increasingly numerous and important group of patients requires.
Author: Sarah Caroline Clement
Publisher:
ISBN: 9789462332553
Category :
Languages : en
Pages : 0
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Book Description
Treatment of pediatric malignancies has advanced substantially over the past several decades, resulting in a rapidly growing group of long-term childhood cancer survivors (CCS). Improved survival leads to an increasing number of individuals who may be at increased risk of substantial morbidity and even mortality as a direct or indirect consequence of their prior cancer therapy. Moreover, many CCS face lifelong health-related challenges after curative treatment of a childhood malignancy. Around 73% of the survivors will experience at least one chronic health-condition within 30 years of their cancer diagnosis, with a 42% cumulative incidence rate for severe, disabling, or life-threatening conditions or death due to a chronic disease. Endocrine disorders are common in CCS, and may not only play a central role in long-term health and wellbeing, but can also significantly diminish short-term health, especially during childhood. In CCS, endocrine integrity is essential for adequate recovery, for development and growth and optimal daily (school) life participation. As in many late adverse effects in CCS, endocrine disturbances are most often related to cancer treatment. Particularly patients receiving radiation therapy and alkylating chemotherapy are at high risk of developing endocrinopathies. In addition to their anti-carcinogenic effects, these therapies may cause direct injury to the hypothalamic-pituitary axis, thyroid gland, and the gonads. The current thesis focuses primarily on the etiology, epidemiology, risk factors and optimal surveillance strategy of diverse endocrine disorders in survivors of a childhood malignancy..
Author: Charles A. Sklar
Publisher: S. Karger AG (Switzerland)
ISBN: 9783318065664
Category :
Languages : en
Pages : 0
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Book Description
This special topic issue addresses the most common endocrine and metabolic complications observed in cancer survivors. It gives an overview to orient endocrinologists to common cancer diagnoses and the therapies most often associated with adverse endocrine outcomes. Additionally, it focuses on the important issues of impaired linear growth, hypogonadism in males and females, disorders of the thyroid gland, diabetes mellitus and the metabolic syndrome, hypothalamic obesity, and disorders of the bone. These state-of-the-art reviews will hopefully assist clinicians in diagnosing and managing the various endocrine disorders experienced by survivors. The goal is to improve quality of life and to reduce morbidity and mortality in a vulnerable population. This publication is a valuable resource for pediatric, adult, and generalist providers caring for childhood cancer and brain tumor survivors.
Author: Lillian Meacham
Publisher:
ISBN:
Category :
Languages : en
Pages :
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Book Description
Author: Sofia Llahana
Publisher: Springer
ISBN: 331999817X
Category : Medical
Languages : en
Pages : 1337
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Book Description
This book provides a comprehensive guide for nurses practicing in any area of endocrinology and at any level of expertise. Endocrinology Nursing is a fast-developing specialty with nurses performing advanced roles and expanding their practice to run independent nurse-led services. Supported by the European Society of Endocrinology (ESE) and edited by members of the ESE Nurses Working Group, this is the first book ever published specifically for endocrine nurses. It is also an excellent resource for endocrinology specialty trainees, general practitioners, medical and nursing students, expert patients and nurses working in specialties such as fertility, osteoporosis, oncology, obesity, urology and gynaecology, who look after patients with endocrine-related disorders. This volume includes 13 sections and 69 chapters providing a comprehensive overview of adult and paediatric endocrinology but also a section on advanced practice, role development and nursing research. It has been written by an international team of more than 100 eminent nurses, physicians, surgeons, psychologists and other healthcare professionals, which makes this book a valuable resource for any multidisciplinary team. Many patient advocacy groups have contributed with case studies which emphasises the close working relationships with patients.
Author: Ajay Vora
Publisher: Springer
ISBN: 3319397087
Category : Medical
Languages : en
Pages : 342
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Book Description
This book provides a comprehensive and up-to-date review of all aspects of childhood Acute Lymphoblastic Leukemia, from basic biology to supportive care. It offers new insights into the genetic pre-disposition to the condition and discusses how response to early therapy and its basic biology are utilized to develop new prognostic stratification systems and target therapy. Readers will learn about current treatment and outcomes, such as immunotherapy and targeted therapy approaches. Supportive care and management of the condition in resource poor countries are also discussed in detail. This is an indispensable guide for research and laboratory scientists, pediatric hematologists as well as specialist nurses involved in the care of childhood leukemia.
Author: National Academies of Sciences Engineering and Medicine
Publisher:
ISBN: 9780309683494
Category :
Languages : en
Pages :
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Book Description
Since the late 1960s, the survival rate in children and adolescents diagnosed with cancer has steadily improved, with a corresponding decline in the cancer-specific death rate. Although the improvements in survival are encouraging, they have come at the cost of acute, chronic, and late adverse effects precipitated by the toxicities associated with the individual or combined use of different types of treatment (e.g., surgery, radiation, chemotherapy). In some cases, the impairments resulting from cancer and its treatment are severe enough to qualify a child for U.S. Social Security Administration disability benefits. At the request of Social Security Administration, Childhood Cancer and Functional Impacts Across the Care Continuum provides current information and findings and conclusions regarding the diagnosis, treatment, and prognosis of selected childhood cancers, including different types of malignant solid tumors, and the effect of those cancers on childrenâ (TM)s health and functional capacity, including the relative levels of functional limitation typically associated with the cancers and their treatment. This report also provides a summary of selected treatments currently being studied in clinical trials and identifies any limitations on the availability of these treatments, such as whether treatments are available only in certain geographic areas.
Author: Jörn D. Beck
Publisher: Springer Nature
ISBN: 3030491404
Category : Medical
Languages : en
Pages : 419
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Book Description
This comprehensive guide describes the aftercare that is appropriate in young cancer patients and discusses in detail the risk and detection of treatment sequelae. It explains the impacts on body and mind of both the disease itself and the different risk-adapted cancer treatments currently in use. Clear guidance is provided on diagnosis and management of the principal treatment-related toxicities in different organs and organ systems and for a wide variety of tumor types. In addition, the role of genetic polymorphisms in the development of adverse therapy-related outcomes is explored, and advice offered on genetic counselling. As the number of long-term survivors of childhood cancer and of cancer in young adults continues to grow, so issues surrounding potential sequelae, second malignancies, and quality of life are becoming ever more important. All practitioners involved in the care of young cancer patients will find this book to be a helpful source of up-to-date information and assistance.
Author: Sally Radovick
Publisher: Springer
ISBN: 3319737821
Category : Medical
Languages : en
Pages : 882
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Book Description
A state-of-the-art and concise resource presenting the clinical management of pediatric endocrine diseases and disorders, this third edition of the highly regarded textbook covers the most common and challenging conditions seen by practicing endocrinologists and primary care physicians, including growth, hypothalamic, pituitary, adrenal, thyroid, calcium and bone, and reproductive disorders, as well as metabolic syndromes. This expanded third edition includes new topics such as conditions of overgrowth, low bone density and its management, endocrine issues related to sexual identity, mineralocorticoid disorders and endocrine hypertension, and endocrine emergencies. Some existing chapters are expanded to take into account recent advances in the field. Each chapter contains key points, an introductory discussion of the problem, a review of the clinical features that characterize it, the criteria needed to establish a diagnosis, and a comprehensive therapy section delineating the risks and benefits of the best therapeutic options available. New to this edition are concluding sections in each chapter containing relevant case material and multiple choice review questions. Pediatric Endocrinology: A Practical Clinical Guide, Third Edition is a comprehensive resource for all clinicians concerned with the myriad endocrinologic disorders seen in children and adolescents.
Author: Jens O. L. Jørgensen
Publisher: Karger Medical and Scientific Publishers
ISBN: 3805579926
Category : Science
Languages : en
Pages : 241
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Book Description
It has been known for over 40 years that GH-deficient-children benefit from replacement with the hormone. But GH, essential for longitudinal growth, also plays a role after completion of final height. With the introduction of biosynthetic human GH 20 years ago, the use of GH was no longer restricted to severe growth retardation in hypopituitary children. This book will take the reader behind the myths of GH and into the real world of clinical endocrinology. The contributions stem from recognized clinicians and scientists who have been working in the field for decades. The contents encompass traditional end points of GH therapy such as body composition, bone biology and physical performance. Attention is also devoted to diagnostic aspects and side effects. Additional features range from clinical epidemiology to quality of life, and novel areas such as the impact of traumatic brain injury on pituitary function are also covered. The present volume of Frontiers of Hormone Research is essential reading for health care professionals interested in clinical endocrinology and GH.
