Genetics, Embryology, and Development of Auditory and Vestibular Systems PDF Download
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Author: Sherri M. Jones
Publisher: Plural Publishing
ISBN: 1597566276
Category : Medical
Languages : en
Pages : 289
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Book Description
Author: Sherri M. Jones
Publisher: Plural Publishing
ISBN: 1597566276
Category : Medical
Languages : en
Pages : 289
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Book Description
Author: Ron Amundson
Publisher: Cambridge University Press
ISBN: 9781139443425
Category : Science
Languages : en
Pages : 302
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Book Description
In this book Ron Amundson examines two hundred years of scientific views on the evolution-development relationship from the perspective of evolutionary developmental biology (evo-devo). This perspective challenges several popular views about the history of evolutionary thought by claiming that many earlier authors had made history come out right for the Evolutionary Synthesis. The book starts with a revised history of nineteenth-century evolutionary thought. It then investigates how development became irrelevant with the Evolutionary Synthesis. It concludes with an examination of the contrasts that persist between mainstream evolutionary theory and evo-devo. This book will appeal to students and professionals in the philosophy and history of science, and biology.
Author: Bruce M. Carlson, MD, PhD
Publisher: Elsevier Health Sciences
ISBN: 1455727946
Category : Medical
Languages : en
Pages : 523
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Book Description
Master the concepts you need to know with Human Embryology and Developmental Biology. Dr. Bruce M. Carlson's clear explanations provide an easy-to-follow "road map" through the most up-to-date scientific knowledge, giving you a deeper understanding of the key information you need to know for your courses, exams, and ultimately clinical practice. Visualize normal and abnormal development with hundreds of superb clinical photos and embryological drawings. Access the fully searchable text online, view animations, answer self-assessment questions, and much more at www.studentconsult.com. Grasp the molecular basis of embryology, including the processes of branching and folding - essential knowledge for determining the root of many abnormalities. Understand the clinical manifestations of developmental abnormalities with clinical vignettes and Clinical Correlations boxes throughout. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should access to the web site be discontinued.
Author: F.Eugene Yates
Publisher: Springer Science & Business Media
ISBN: 1461308836
Category : Science
Languages : en
Pages : 658
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Book Description
Technological systems become organized by commands from outside, as when human intentions lead to the building of structures or machines. But many nat ural systems become structured by their own internal processes: these are the self organizing systems, and the emergence of order within them is a complex phe nomenon that intrigues scientists from all disciplines. Unfortunately, complexity is ill-defined. Global explanatory constructs, such as cybernetics or general sys tems theory, which were intended to cope with complexity, produced instead a grandiosity that has now, mercifully, run its course and died. Most of us have become wary of proposals for an "integrated, systems approach" to complex matters; yet we must come to grips with complexity some how. Now is a good time to reexamine complex systems to determine whether or not various scientific specialties can discover common principles or properties in them. If they do, then a fresh, multidisciplinary attack on the difficulties would be a valid scientific task. Believing that complexity is a proper scientific issue, and that self-organizing systems are the foremost example, R. Tomovic, Z. Damjanovic, and I arranged a conference (August 26-September 1, 1979) in Dubrovnik, Yugoslavia, to address self-organizing systems. We invited 30 participants from seven countries. Included were biologists, geologists, physicists, chemists, mathematicians, bio physicists, and control engineers. Participants were asked not to bring manu scripts, but, rather, to present positions on an assigned topic. Any writing would be done after the conference, when the writers could benefit from their experi ences there.
Author: Deborah Lynn Steinberg
Publisher: Manchester University Press
ISBN: 9780719046681
Category : Literary Criticism
Languages : en
Pages : 246
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Book Description
An imaginative and original reappraisal of reproductive science, Bodies in glass explores the complex cultural landscape and emergent iconographic bodies of in vitro fertilisation (IVF) and medical genetic discourse. Through a compelling deconstruction of medical and legal languages, texts and institutional practices, Deborah Lynn Steinberg traces the convergence of four key logics - authorial, recombinant, embryo-protectionist and eugenic - which, she argues, are embedded in the field of IVF; the textual material processes of erasure and recombination of women's bodies and reproductive 'fitness'.
Author: Frank J. Dye
Publisher: John Wiley & Sons
ISBN: 1118076516
Category : Science
Languages : en
Pages : 257
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Book Description
A newly revised edition of the standard reference for the field today—updated with new terms, major discoveries, significant scientists, and illustrations Developmental biology is the study of the mechanisms of development, differentiation, and growth in animals and plants at the molecular, cellular, and genetic levels. The discipline has gained prominence in part due to new interdisciplinary approaches and advances in technology, which have led to the rapid emergence of new concepts and words. The Dictionary of Developmental Biology and Embryology, Second Edition is the first comprehensive reference focused on the field's terms, research, history, and people. This authoritative A-to-Z resource covers classical morphological and cytological terms along with those from modern genetics and molecular biology. Extensively cross-referenced, the Dictionary includes definitions of terms, explanations of concepts, and biographies of historical figures. Comparative aspects are described in order to provide a sense of the evolution of structures, and topics range from fundamental terminology, germ layers, and induction to RNAi, evo-devo, stem cell differentiation, and more. Readers will find such features of embryology and developmental biology as: Vertebrates Invertebrates Plants Developmental genetics Evolutionary developmental biology Molecular developmental biology Medical embryology The author's premium on accessibility allows readers at all levels to enhance their vocabulary in their field and understand terminology beyond their specific focus. Researchers and students in developmental biology, cell biology, developmental genetics, and embryology will find the dictionary to be a vital resource.
Author: Simón Carlos
Publisher:
ISBN: 9783036511528
Category :
Languages : en
Pages : 176
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Book Description
Dear Colleagues, The science of human genetics has advanced at an exponential pace since the double-helix structure of DNA was identified in 1953. Within only 25 years of that discovery, the first gene was sequenced. Subsequent efforts in the span of a few decades have brought advanced next-generation sequencing and new tools for genome editing, allowing scientists to write and rewrite the code of life. We are now realizing that genetics represents yet another system of information technology that follows Moore's law, stating that computer processing power roughly doubles every two years. Importantly, with such rapid and sophisticated advancements, any tools or studies applicable to adult genetics can now also be applied to embryos. Genetic disorders affect 1% of live births and are responsible for 20% of pediatric hospitalizations and 20% of infant mortality. Many disorders are caused by recessive or X-linked genetic mutations carried by 85% of humans. Because assisted reproduction has armed us with technologies like in vitro fertilization that provide access to human embryos, we began to screen some genetic diseases simply by selecting sex. The first live births following preimplantation genetic testing (PGT) to identify sex in X-linked disease were reported by Alan Handyside in 1990. This groundbreaking work used the identification of male embryos and selective transfer of unaffected normal or carrier females as proof-of-concept to avoid genetic diseases, paving the way to extend the concept to PGT for monogenic diseases (PGT-M), including Mendelian single-gene defects (autosomal dominant/recessive, X-linked dominant/recessive), severe childhood lethality or early-onset disease, cancer predisposition, and HLA typing for histocompatible cord-blood stem cells' transplantation. Later, we moved onto the identification and selection of euploid embryos by analysing all 23 pairs of chromosomes in 4-8 cells from the trophectoderm, called PGT for aneuploidy (PGT-A). PGT-A currently leverages next-generation sequencing technologies to uncover meiotic- and mitotic-origin aneuploidies affecting whole chromosomes, as well as duplications/deletions of small chromosome regions. A step forward was the use of structural chromosome rearrangements (PGT-SR) to identify Robertsonian and reciprocal translocations, inversions, and balanced vs. unbalanced rearrangements. Another advancement came with PGT for polygenic risk scoring (PGT-P). This technique takes us from learning how to read simple words to starting to understand poetry (i.e., evolving from PGT-M/A/SR to PGT-P for multifactorial, polygenic risk prediction). Common multifactorial diseases like diabetes, coronary heart disease, and cancer are caused by a combination of environmental, lifestyle, and genetic factors; risk scores are now being generated to predict the likelihood of such complex, later-life diseases in embryos. Moreover, we are moving from embryo selection to intervention because the genetic code is not only readable, but also re-writeable. Indeed, gene editing is now possible using tools like CRISPR/Cas9, which are applicable to all species, including human embryos. In this Special Issue, we invite reviews, primers, and original research papers that contribute to our understanding of human embryo genetics. Specifically, we would like to compile the current knowledge in PGT for monogenic diseases (PGT-M), PGT for aneuploidy (PGT-A) including mosaicism, PGT for polygenic risk scoring (PGT-P), and gene editing in human embryos. Manuscripts can target both basic science as well as the clinical impact of embryogenetics in reproductive medicine, maternal-fetal medicine, and pediatrics. We look forward to your submissions
Author: Scott F. Gilbert
Publisher: Macmillan
ISBN: 9780716773450
Category : Medical
Languages : en
Pages : 316
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Book Description
"This brief textbook of human development covers the events of fertilization, gestation, and sex determination, followed by descriptions of the science of cloning, stem cells, and genome sequencing. The chapter covering the science is juxtaposed with a chapter discussing ethical questions that arise, such as when does life begin, should assisted reproductive technologies be regulated, and should parents be allowed to choose their child's sex"--Provided by publisher.
Author: Jean Brachet
Publisher: Springer Science & Business Media
ISBN: 3642828833
Category : Medical
Languages : en
Pages : 241
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Book Description
Nearly 10 years have elapsed since I finished writing the first edition of Intro duction to Molecular Embryology. During this period, molecular embryology has made great strides forward, but without undergoing a major revolution; there fore, the general philosophy and outline of the book have remained almost un changed. However, all the chapters had to be almost completely rewritten in or der to introduce new facts and to eliminate findings which have lost interest or have been disproved. There was a major gap in the first edition of this book: very little was said about mammalian eggs despite their obvious interest for mankind. Research on mammalian eggs and embryos is so active today that this important topic deserves a full chapter in a book concerned with molecular embryology. Therefore, I am very thankful to my colleague Dr. Henri Alexandre, who has written a chapter on mammalian embryology (Chap. 9) and has prepared all the illustrations for this book.
Author: Sally A. Moody
Publisher: Elsevier
ISBN: 0080550711
Category : Science
Languages : en
Pages : 1094
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Book Description
Unlike anything currently available in the market, Dr. Sally A. Moody and a team of world-renowned experts provide a groundbreaking view of developmental genetics that will influence scientific approaches in embryology, comparative biology, as well as the newly emerging fields of stem cell biology and regenerative medicine. Principles of Developmental Genetics highlights the intersection of developmental biology with new revolutionary genomic technologies, and details how these advances have accelerated our understanding of the molecular genetic processes that regulates development. This definitive resource provides researchers with the opportunity to gain important insights into the clinical applicability of emerging new technologies and animal model data. This book is a must-have for all researchers in genetics, developmental biology, regenerative medicine, and stem cell biology.• Includes new research not previously published in any other book on the molecular geneticprocesses that regulates development• Chapters present a broad understanding on the application of animal model systems, allowingresearchers to better treat clinical disorders and comprehend human development• Relates the application of new technologies to the manipulation of stem cells, causes ofhuman birth defects, and several human disease conditions• Each chapter includes a bulleted summary highlighting clinical aspects of animal models
