Author:
Publisher:
ISBN:
Category : Military art and science
Languages : en
Pages : 400
Book Description
Parameters
Author:
Publisher:
ISBN:
Category : Military art and science
Languages : en
Pages : 400
Book Description
Publisher:
ISBN:
Category : Military art and science
Languages : en
Pages : 400
Book Description
Generic
Author: Jeremy A. Greene
Publisher: Johns Hopkins University Press
ISBN: 142142164X
Category : Medical
Languages : en
Pages : 375
Book Description
The turbulent history of generic pharmaceuticals raises powerful questions about similarity and difference in modern medicine. Generic drugs are now familiar objects in clinics, drugstores, and households around the world. We like to think of these tablets, capsules, patches, and ointments as interchangeable with their brand-name counterparts: why pay more for the same? And yet they are not quite the same. They differ in price, in place of origin, in color, shape, and size, in the dyes, binders, fillers, and coatings used, and in a host of other ways. Claims of generic equivalence, as physician-historian Jeremy Greene reveals in this gripping narrative, are never based on being identical to the original drug in all respects, but in being the same in all ways that matter. How do we know what parts of a pill really matter? Decisions about which differences are significant and which are trivial in the world of therapeutics are not resolved by simple chemical or biological assays alone. As Greene reveals in this fascinating account, questions of therapeutic similarity and difference are also always questions of pharmacology and physiology, of economics and politics, of morality and belief. Generic is the first book to chronicle the social, political, and cultural history of generic drugs in America. It narrates the evolution of the generic drug industry from a set of mid-twentieth-century "schlock houses" and "counterfeiters" into an agile and surprisingly powerful set of multinational corporations in the early twenty-first century. The substitution of bioequivalent generic drugs for more expensive brand-name products is a rare success story in a field of failed attempts to deliver equivalent value in health care for a lower price. Greene’s history sheds light on the controversies shadowing the success of generics: problems with the generalizability of medical knowledge, the fragile role of science in public policy, and the increasing role of industry, marketing, and consumer logics in late-twentieth-century and early twenty-first century health care.
Publisher: Johns Hopkins University Press
ISBN: 142142164X
Category : Medical
Languages : en
Pages : 375
Book Description
The turbulent history of generic pharmaceuticals raises powerful questions about similarity and difference in modern medicine. Generic drugs are now familiar objects in clinics, drugstores, and households around the world. We like to think of these tablets, capsules, patches, and ointments as interchangeable with their brand-name counterparts: why pay more for the same? And yet they are not quite the same. They differ in price, in place of origin, in color, shape, and size, in the dyes, binders, fillers, and coatings used, and in a host of other ways. Claims of generic equivalence, as physician-historian Jeremy Greene reveals in this gripping narrative, are never based on being identical to the original drug in all respects, but in being the same in all ways that matter. How do we know what parts of a pill really matter? Decisions about which differences are significant and which are trivial in the world of therapeutics are not resolved by simple chemical or biological assays alone. As Greene reveals in this fascinating account, questions of therapeutic similarity and difference are also always questions of pharmacology and physiology, of economics and politics, of morality and belief. Generic is the first book to chronicle the social, political, and cultural history of generic drugs in America. It narrates the evolution of the generic drug industry from a set of mid-twentieth-century "schlock houses" and "counterfeiters" into an agile and surprisingly powerful set of multinational corporations in the early twenty-first century. The substitution of bioequivalent generic drugs for more expensive brand-name products is a rare success story in a field of failed attempts to deliver equivalent value in health care for a lower price. Greene’s history sheds light on the controversies shadowing the success of generics: problems with the generalizability of medical knowledge, the fragile role of science in public policy, and the increasing role of industry, marketing, and consumer logics in late-twentieth-century and early twenty-first century health care.
The Quarterly Journal of the University of North Dakota
Author: University of North Dakota
Publisher:
ISBN:
Category :
Languages : en
Pages : 482
Book Description
Publisher:
ISBN:
Category :
Languages : en
Pages : 482
Book Description
The Quarterly Journal - University of North Dakota
Author: University of North Dakota
Publisher:
ISBN:
Category :
Languages : en
Pages : 484
Book Description
Vol. 1 includes "the installation of Frank Le Rond Mc Vey...as president of the University of North Dakota. Programs and proceedings." Called inauguration number, dated Sept. 1910.
Publisher:
ISBN:
Category :
Languages : en
Pages : 484
Book Description
Vol. 1 includes "the installation of Frank Le Rond Mc Vey...as president of the University of North Dakota. Programs and proceedings." Called inauguration number, dated Sept. 1910.
In the Shadow of the Garrison State
Author: Aaron L. Friedberg
Publisher: Princeton University Press
ISBN: 1400842913
Category : Political Science
Languages : en
Pages : 416
Book Description
War--or the threat of war--usually strengthens states as governments tax, draft soldiers, exert control over industrial production, and dampen internal dissent in order to build military might. The United States, however, was founded on the suspicion of state power, a suspicion that continued to gird its institutional architecture and inform the sentiments of many of its politicians and citizens through the twentieth century. In this comprehensive rethinking of postwar political history, Aaron Friedberg convincingly argues that such anti-statist inclinations prevented Cold War anxieties from transforming the United States into the garrison state it might have become in their absence. Drawing on an array of primary and secondary sources, including newly available archival materials, Friedberg concludes that the "weakness" of the American state served as a profound source of national strength that allowed the United States to outperform and outlast its supremely centralized and statist rival: the Soviet Union. Friedberg's analysis of the U. S. government's approach to taxation, conscription, industrial planning, scientific research and development, and armaments manufacturing reveals that the American state did expand during the early Cold War period. But domestic constraints on its expansion--including those stemming from mean self-interest as well as those guided by a principled belief in the virtues of limiting federal power--protected economic vitality, technological superiority, and public support for Cold War activities. The strategic synthesis that emerged by the early 1960s was functional as well as stable, enabling the United States to deter, contain, and ultimately outlive the Soviet Union precisely because the American state did not limit unduly the political, personal, and economic freedom of its citizens. Political scientists, historians, and general readers interested in Cold War history will value this thoroughly researched volume. Friedberg's insightful scholarship will also inspire future policy by contributing to our understanding of how liberal democracy's inherent qualities nurture its survival and spread.
Publisher: Princeton University Press
ISBN: 1400842913
Category : Political Science
Languages : en
Pages : 416
Book Description
War--or the threat of war--usually strengthens states as governments tax, draft soldiers, exert control over industrial production, and dampen internal dissent in order to build military might. The United States, however, was founded on the suspicion of state power, a suspicion that continued to gird its institutional architecture and inform the sentiments of many of its politicians and citizens through the twentieth century. In this comprehensive rethinking of postwar political history, Aaron Friedberg convincingly argues that such anti-statist inclinations prevented Cold War anxieties from transforming the United States into the garrison state it might have become in their absence. Drawing on an array of primary and secondary sources, including newly available archival materials, Friedberg concludes that the "weakness" of the American state served as a profound source of national strength that allowed the United States to outperform and outlast its supremely centralized and statist rival: the Soviet Union. Friedberg's analysis of the U. S. government's approach to taxation, conscription, industrial planning, scientific research and development, and armaments manufacturing reveals that the American state did expand during the early Cold War period. But domestic constraints on its expansion--including those stemming from mean self-interest as well as those guided by a principled belief in the virtues of limiting federal power--protected economic vitality, technological superiority, and public support for Cold War activities. The strategic synthesis that emerged by the early 1960s was functional as well as stable, enabling the United States to deter, contain, and ultimately outlive the Soviet Union precisely because the American state did not limit unduly the political, personal, and economic freedom of its citizens. Political scientists, historians, and general readers interested in Cold War history will value this thoroughly researched volume. Friedberg's insightful scholarship will also inspire future policy by contributing to our understanding of how liberal democracy's inherent qualities nurture its survival and spread.
Classic Issues in Soviet Foreign Policy
Author: Frederic J. Fleron (jr.)
Publisher: Transaction Publishers
ISBN: 9780202364841
Category : Political Science
Languages : en
Pages : 372
Book Description
Theoretical and empirical studies of Soviet foreign policy from the Revolution to the mid 1960s, including historical, methodological, and ideological perspectives. Reported available with its companion, covering Breshnev to Gorbachev, as a single volume (unseen). (c) by Book News, Inc., Portland, OR.
Publisher: Transaction Publishers
ISBN: 9780202364841
Category : Political Science
Languages : en
Pages : 372
Book Description
Theoretical and empirical studies of Soviet foreign policy from the Revolution to the mid 1960s, including historical, methodological, and ideological perspectives. Reported available with its companion, covering Breshnev to Gorbachev, as a single volume (unseen). (c) by Book News, Inc., Portland, OR.
LBJ and the Presidential Management of Foreign Relations
Author: Paul Y. Hammond
Publisher: Univ of TX + ORM
ISBN: 0292773137
Category : Political Science
Languages : en
Pages : 469
Book Description
In this insightful study, Paul Y. Hammond, an experienced analyst of bureaucratic politics, adapts and extends that approach to explain and evaluate the Johnson administration’s performance in foreign relations in terms that have implications for the post–Cold War era. The book is structured around three case studies of Johnson’s foreign policy decision making. The first study examines economic and political development. It explores the way Johnson handled the provision of economic and food assistance to India during a crisis in India’s food policies. This analysis provides lessons not only for dealing with African famine in later years but also for assisting Eastern Europe and the former Soviet Union. The second case study focuses on U.S. relations with Western Europe at a time that seemed to require a major change in the NATO alliance. Here, Hammond illuminates the process of policy innovation, particularly the costs of changing well-established policies that embody an elaborate network of established interests. The third case study treats the Vietnam War, with special emphasis on how Johnson decided what to do about Vietnam. Hammond critiques the rich scholarship available on Johnson’s advisory process, based on his own reading of the original sources. These case studies are set in a larger context of applied theory that deals more generally with presidential management of foreign relations, examining a president’s potential for influence on the one hand and the constraints on his or her capacity to control and persuade on the other. It will be important reading for all scholars and policymakers interested in the limits and possibilities of presidential power in the post–Cold War era.
Publisher: Univ of TX + ORM
ISBN: 0292773137
Category : Political Science
Languages : en
Pages : 469
Book Description
In this insightful study, Paul Y. Hammond, an experienced analyst of bureaucratic politics, adapts and extends that approach to explain and evaluate the Johnson administration’s performance in foreign relations in terms that have implications for the post–Cold War era. The book is structured around three case studies of Johnson’s foreign policy decision making. The first study examines economic and political development. It explores the way Johnson handled the provision of economic and food assistance to India during a crisis in India’s food policies. This analysis provides lessons not only for dealing with African famine in later years but also for assisting Eastern Europe and the former Soviet Union. The second case study focuses on U.S. relations with Western Europe at a time that seemed to require a major change in the NATO alliance. Here, Hammond illuminates the process of policy innovation, particularly the costs of changing well-established policies that embody an elaborate network of established interests. The third case study treats the Vietnam War, with special emphasis on how Johnson decided what to do about Vietnam. Hammond critiques the rich scholarship available on Johnson’s advisory process, based on his own reading of the original sources. These case studies are set in a larger context of applied theory that deals more generally with presidential management of foreign relations, examining a president’s potential for influence on the one hand and the constraints on his or her capacity to control and persuade on the other. It will be important reading for all scholars and policymakers interested in the limits and possibilities of presidential power in the post–Cold War era.
Models of Massive Parallelism
Author: Max Garzon
Publisher: Springer Science & Business Media
ISBN: 3642779050
Category : Computers
Languages : en
Pages : 284
Book Description
Locality is a fundamental restriction in nature. On the other hand, adaptive complex systems, life in particular, exhibit a sense of permanence and time lessness amidst relentless constant changes in surrounding environments that make the global properties of the physical world the most important problems in understanding their nature and structure. Thus, much of the differential and integral Calculus deals with the problem of passing from local information (as expressed, for example, by a differential equation, or the contour of a region) to global features of a system's behavior (an equation of growth, or an area). Fundamental laws in the exact sciences seek to express the observable global behavior of physical objects through equations about local interaction of their components, on the assumption that the continuum is the most accurate model of physical reality. Paradoxically, much of modern physics calls for a fundamen tal discrete component in our understanding of the physical world. Useful computational models must be eventually constructed in hardware, and as such can only be based on local interaction of simple processing elements.
Publisher: Springer Science & Business Media
ISBN: 3642779050
Category : Computers
Languages : en
Pages : 284
Book Description
Locality is a fundamental restriction in nature. On the other hand, adaptive complex systems, life in particular, exhibit a sense of permanence and time lessness amidst relentless constant changes in surrounding environments that make the global properties of the physical world the most important problems in understanding their nature and structure. Thus, much of the differential and integral Calculus deals with the problem of passing from local information (as expressed, for example, by a differential equation, or the contour of a region) to global features of a system's behavior (an equation of growth, or an area). Fundamental laws in the exact sciences seek to express the observable global behavior of physical objects through equations about local interaction of their components, on the assumption that the continuum is the most accurate model of physical reality. Paradoxically, much of modern physics calls for a fundamen tal discrete component in our understanding of the physical world. Useful computational models must be eventually constructed in hardware, and as such can only be based on local interaction of simple processing elements.
A Course in Simple-Homotopy Theory
Author: M.M. Cohen
Publisher: Springer Science & Business Media
ISBN: 1468493728
Category : Mathematics
Languages : en
Pages : 124
Book Description
This book grew out of courses which I taught at Cornell University and the University of Warwick during 1969 and 1970. I wrote it because of a strong belief that there should be readily available a semi-historical and geo metrically motivated exposition of J. H. C. Whitehead's beautiful theory of simple-homotopy types; that the best way to understand this theory is to know how and why it was built. This belief is buttressed by the fact that the major uses of, and advances in, the theory in recent times-for example, the s-cobordism theorem (discussed in §25), the use of the theory in surgery, its extension to non-compact complexes (discussed at the end of §6) and the proof of topological invariance (given in the Appendix)-have come from just such an understanding. A second reason for writing the book is pedagogical. This is an excellent subject for a topology student to "grow up" on. The interplay between geometry and algebra in topology, each enriching the other, is beautifully illustrated in simple-homotopy theory. The subject is accessible (as in the courses mentioned at the outset) to students who have had a good one semester course in algebraic topology. I have tried to write proofs which meet the needs of such students. (When a proof was omitted and left as an exercise, it was done with the welfare of the student in mind. He should do such exercises zealously.
Publisher: Springer Science & Business Media
ISBN: 1468493728
Category : Mathematics
Languages : en
Pages : 124
Book Description
This book grew out of courses which I taught at Cornell University and the University of Warwick during 1969 and 1970. I wrote it because of a strong belief that there should be readily available a semi-historical and geo metrically motivated exposition of J. H. C. Whitehead's beautiful theory of simple-homotopy types; that the best way to understand this theory is to know how and why it was built. This belief is buttressed by the fact that the major uses of, and advances in, the theory in recent times-for example, the s-cobordism theorem (discussed in §25), the use of the theory in surgery, its extension to non-compact complexes (discussed at the end of §6) and the proof of topological invariance (given in the Appendix)-have come from just such an understanding. A second reason for writing the book is pedagogical. This is an excellent subject for a topology student to "grow up" on. The interplay between geometry and algebra in topology, each enriching the other, is beautifully illustrated in simple-homotopy theory. The subject is accessible (as in the courses mentioned at the outset) to students who have had a good one semester course in algebraic topology. I have tried to write proofs which meet the needs of such students. (When a proof was omitted and left as an exercise, it was done with the welfare of the student in mind. He should do such exercises zealously.
The Arms Control, Disarmament, and Military Security Dictionary
Author: Jeffrey M. Elliot
Publisher: Wildside Press LLC
ISBN: 1434490521
Category : Political Science
Languages : en
Pages : 366
Book Description
This facsimile reprint of the 1989 edition is, according to Library Journal, ..".a wonderfully concise and comprehensive resource on a very important topic. In 268 detailed entries, the authors provide a wealth of information on such topics as the arms race, conventional and nuclear weapons, nuclear strategy, and disarmament. The entries are cross-referenced, and there is an index. Of great value to general readers as well as specialists."
Publisher: Wildside Press LLC
ISBN: 1434490521
Category : Political Science
Languages : en
Pages : 366
Book Description
This facsimile reprint of the 1989 edition is, according to Library Journal, ..".a wonderfully concise and comprehensive resource on a very important topic. In 268 detailed entries, the authors provide a wealth of information on such topics as the arms race, conventional and nuclear weapons, nuclear strategy, and disarmament. The entries are cross-referenced, and there is an index. Of great value to general readers as well as specialists."