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Author: Henry Gee
Publisher: W. W. Norton & Company
ISBN: 9780393050837
Category : Science
Languages : en
Pages : 300
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Book Description
Discusses what can be understood through human genome sequencing, describes how the interactions of genes direct the growth of individuals, and reveals what gene research will enable in the future.
Author: Henry Gee
Publisher: W. W. Norton & Company
ISBN: 9780393050837
Category : Science
Languages : en
Pages : 300
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Book Description
Discusses what can be understood through human genome sequencing, describes how the interactions of genes direct the growth of individuals, and reveals what gene research will enable in the future.
Author: National Research Council
Publisher: National Academies Press
ISBN: 0309038405
Category : Science
Languages : en
Pages : 128
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Book Description
There is growing enthusiasm in the scientific community about the prospect of mapping and sequencing the human genome, a monumental project that will have far-reaching consequences for medicine, biology, technology, and other fields. But how will such an effort be organized and funded? How will we develop the new technologies that are needed? What new legal, social, and ethical questions will be raised? Mapping and Sequencing the Human Genome is a blueprint for this proposed project. The authors offer a highly readable explanation of the technical aspects of genetic mapping and sequencing, and they recommend specific interim and long-range research goals, organizational strategies, and funding levels. They also outline some of the legal and social questions that might arise and urge their early consideration by policymakers.
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309452880
Category : Medical
Languages : en
Pages : 329
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Book Description
Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.
Author: Claudia Gonzaga-Jauregui
Publisher: Academic Press
ISBN: 0128204362
Category : Medical
Languages : en
Pages : 318
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Book Description
Genomics of Rare Diseases: Understanding Disease Genetics Using Genomic Approaches, a new volume in the Translational and Applied Genomics series, offers readers a broad understanding of current knowledge on rare diseases through a genomics lens. This clear understanding of the latest molecular and genomic technologies used to elucidate the molecular causes of more than 5,000 genetic disorders brings readers closer to unraveling many more that remain undefined and undiscovered. The challenges associated with performing rare disease research are also discussed, as well as the opportunities that the study of these disorders provides for improving our understanding of disease architecture and pathophysiology. Leading chapter authors in the field discuss approaches such as karyotyping and genomic sequencing for the better diagnosis and treatment of conditions including recessive diseases, dominant and X-linked disorders, de novo mutations, sporadic disorders and mosaicism. - Compiles applied case studies and methodologies, enabling researchers, clinicians and healthcare providers to effectively classify DNA variants associated with disease and patient phenotypes - Discusses the main challenges in studying the genetics of rare diseases through genomic approaches and possible or ongoing solutions - Explores opportunities for novel therapeutics - Features chapter contributions from leading researchers and clinicians
Author: Nicolas Jouve de la Barreda
Publisher: Digital Reasons
ISBN: 8410093049
Category : Science
Languages : en
Pages : 264
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Book Description
Un panorama general, básico y didáctico sobre la singularidad genética y biológica de la especie humana. Tras la creación del universo con el big-bang hace 13.700 millones de años brotó la vida en un planeta idóneo para su expansión y diversificación. En el libro se detallan los mecanismos de la evolución y de la aparición del Homo sapiens a partir de unos ancestros prehomínidos en el centro de África, hasta su expansión por todo el mundo. Se describen los procesos de la hominización y humanización y las especiales características del ser humano. Se explica el significado del “fenómeno humano” y el por qué y el cómo del resurgir de una especie tan singular. La única que asciende al mundo de la racionalidad y que en consecuencia vive su vida de forma consciente, se comunica con sus congéneres, crea la cultura y domina su entorno con un sentido ético y de trascendencia. En el libro se describen los fundamentos genéticos de nuestros rasgos biológicos, los determinantes genéticos y ambientales que influyen en el comportamiento humano, las enfermedades hereditarias y los detalles de nuestro genoma en relación con el de los demás seres vivos. Se distingue entre lo innato y lo adquirido. Se derriban los mitos y se asientan las pruebas de lo que es genuinamente humano y lo que no lo es. También se aborda el futuro de la humanidad en la era de las tecnologías emergentes, con los desafíos éticos de la manipulación genética y las corrientes materialistas que tratan de conducir a nuestra singular especie a la utopía transhumanista y posthumanista.
Author: The Royal Society
Publisher: National Academies Press
ISBN: 0309671132
Category : Medical
Languages : en
Pages : 239
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Book Description
Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.
Author:
Publisher: Elsevier España
ISBN: 8490220654
Category :
Languages : en
Pages : 2145
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Book Description
Author: Françoise Baylis
Publisher: Harvard University Press
ISBN: 0674976711
Category : Science
Languages : en
Pages : 305
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Book Description
A leading bioethicist offers critical insights into the scientific, ethical, and political implications of human genome editing. Designer babies, once found only in science fiction, have become a reality. We are entering a new era of human evolution with the advent of a technology called CRISPR, which allows scientists to modify our genes. Although CRISPR shows great promise for therapeutic use, it raises thorny ethical, legal, political, and societal concerns because it can be used to make permanent changes to future generations. What if changes intended for the good turn out to have unforeseen negative effects? What if the divide between the haves and have-nots widens as a result? Who decides whether we genetically modify human beings and, if so, how? Françoise Baylis insists that we must all have a role in determining our future as a species. The scientists who develop and use genome-editing tools should not be the only ones making decisions about future uses of the technology. Such decisions must be the fruit of a broad societal consensus. Baylis argues that it is in our collective interest to assess and steer the development and implementation of biomedical technologies. Members of the public with different interests and diverse perspectives must be among the decision makers; only in this way can we ensure that societal concerns are taken into account and that responsible decisions are made. We must be engaged and informed, think critically, and raise our voices as we create our future together. Sharp, rousing, timely, and thought-provoking, Altered Inheritance is essential reading. The future of humanity is in our hands.
Author: Bartolomé Yankovic Nola
Publisher: RIL Editores
ISBN: 9562845443
Category :
Languages : es
Pages : 146
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Book Description
Author: Ryanne Maxine Meyersohn
Publisher: Rosa Amelia Figueroa Nieves
ISBN:
Category : History
Languages : en
Pages : 1085
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Book Description
‘PREMIOS’ ‘Medalla de Plata – Concurso de Libros Favoritos de los Lectores Internacionales y Reseñas de 5 Estrellas’ ‘Premio de Oro al Libro Literario Titan y Reseñas de 5 Estrellas’ ‘Bestseller en Amazon – #1 Historia de Oriente Medio y #2 Historia de Civilizaciones Antiguas’ Los dioses Anunnaki del planeta Nibiru llevaron a cabo una misión en la Tierra, y la historia fue documentada en tabletas de arcilla o textos mesopotámicos descubiertos en las ruinas de edificios en Oriente Medio. Los académicos han propuesto que algunas historias del Génesis ya habían aparecido en textos Mesopotámicos hace miles de años. Esta propuesta nos motivó a evaluar los textos más relevantes. Aunque la mayoría de los académicos creen que los textos mesopotámicos son mitología, la investigación se realizó bajo la premisa de que su contenido corresponde a hechos reales. El análisis de las traducciones académicas de los textos reveló que muchos detalles críticos para comprender la historia no han sido revelados. Un análisis exhaustivo de los datos determinó las fechas más probables de los hechos. El libro presenta los acontecimientos relacionados con la llegada de los Anunnaki a la Tierra y las consecuencias de su misión de manera cronológica según los hallazgos en textos Mesopotámicos y libros antiguos. Diversas fuentes, entre ellas libros apócrifos, informes de historiadores antiguos, investigaciones científicas y registros arqueológicos, complementaron la investigación. Se descifraron muchos enigmas, entre ellos quiénes eran los Anunnaki y los Igigi (vigilantes, Nephilim). ¿Por qué, cuándo y cómo se originó el H. sapiens, cómo surgieron las otras especies y por qué se extinguieron? ¿Por qué y cuándo llegaron los Anunnaki y finalmente abandonaron la Tierra? ¿Cuándo regresará el planeta Nibiru a nuestra zona en el sistema solar interior? Los resultados y hallazgos de esta investigación merecen ser conocidos debido a la probabilidad de que las historias de los textos Mesopotámicos realmente sucedieran. Las propuestas del libro difieren de lo que hemos aprendido en las instituciones educativas sobre el origen de la humanidad e invitan al pensamiento crítico para reflexionar sobre la historia de los dioses Anunnaki. Los lectores entusiastas de la temática extraterrestre encontrarán propuestas innovadoras.
