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Author: Hans-Dieter Klenk
Publisher: Garland Science
ISBN: 9780954523237
Category : Cell physiology
Languages : en
Pages : 392
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Book Description
The Ebola and Marburg viruses are a pair of filoviruses that are among the most lethal hemorrhagic viruses on the planet. The authors present a review of past and current research into these pathogens, including 12 papers addressing the structure of the viral proteins; genomic replication; molecular mechanisms of entry; pathogenesis in nonhuman primates, guinea pigs, and mice; virus modulation of innate immunity; and cellular and molecular mechanisms of Ebola pathogenicity and related approaches to vaccine development.
Author: Hans-Dieter Klenk
Publisher: Garland Science
ISBN: 9780954523237
Category : Cell physiology
Languages : en
Pages : 392
Get Book Here
Book Description
The Ebola and Marburg viruses are a pair of filoviruses that are among the most lethal hemorrhagic viruses on the planet. The authors present a review of past and current research into these pathogens, including 12 papers addressing the structure of the viral proteins; genomic replication; molecular mechanisms of entry; pathogenesis in nonhuman primates, guinea pigs, and mice; virus modulation of innate immunity; and cellular and molecular mechanisms of Ebola pathogenicity and related approaches to vaccine development.
Author:
Publisher:
ISBN:
Category : Electronic information resources
Languages : en
Pages :
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Book Description
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309450063
Category : Medical
Languages : en
Pages : 137
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Book Description
The most recent Ebola epidemic that began in late 2013 alerted the entire world to the gaps in infectious disease emergency preparedness and response. The regional outbreak that progressed to a significant public health emergency of international concern (PHEIC) in a matter of months killed 11,310 and infected more than 28,616. While this outbreak bears some unique distinctions to past outbreaks, many characteristics remain the same and contributed to tragic loss of human life and unnecessary expenditure of capital: insufficient knowledge of the disease, its reservoirs, and its transmission; delayed prevention efforts and treatment; poor control of the disease in hospital settings; and inadequate community and international responses. Recognizing the opportunity to learn from the countless lessons of this epidemic, the National Academies of Sciences, Engineering, and Medicine convened a workshop in March 2015 to discuss the challenges to successful outbreak responses at the scientific, clinical, and global health levels. Workshop participants explored the epidemic from multiple perspectives, identified important questions about Ebola that remained unanswered, and sought to apply this understanding to the broad challenges posed by Ebola and other emerging pathogens, to prevent the international community from being taken by surprise once again in the face of these threats. This publication summarizes the presentations and discussions from the workshop.
Author: Institute of Medicine
Publisher: National Academies Press
ISBN: 0309314003
Category : Medical
Languages : en
Pages : 310
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Book Description
In the past half century, deadly disease outbreaks caused by novel viruses of animal origin - Nipah virus in Malaysia, Hendra virus in Australia, Hantavirus in the United States, Ebola virus in Africa, along with HIV (human immunodeficiency virus), several influenza subtypes, and the SARS (sudden acute respiratory syndrome) and MERS (Middle East respiratory syndrome) coronaviruses - have underscored the urgency of understanding factors influencing viral disease emergence and spread. Emerging Viral Diseases is the summary of a public workshop hosted in March 2014 to examine factors driving the appearance, establishment, and spread of emerging, re-emerging and novel viral diseases; the global health and economic impacts of recently emerging and novel viral diseases in humans; and the scientific and policy approaches to improving domestic and international capacity to detect and respond to global outbreaks of infectious disease. This report is a record of the presentations and discussion of the event.
Author: Hilaire Verreau
Publisher:
ISBN: 9781536162912
Category : Ebola virus disease
Languages : en
Pages : 118
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Book Description
To mitigate the spread of the rare and deadly disease Ebola, Ebola Virus Disease (EVD): Outbreaks, Control and Prevention Strategies begins with the proposition of a mathematical model with vital dynamics and two preventive measures: quarantine and isolation. Humanitarian issues in Ebola prevention and control are explored, as well as the cultural practices and social norms during outbreaks. Additionally, some innovative approaches in the humanitarian response to prevention and control are discussed. The authors expose the dilemma Ebola poses to within the healthcare system, where healthcare providers are caught between the over-arching quest for self-preservation from a highly virulent disease and the professional demand of prioritising the interests of the patients over self. In conclusion, the authors describe successfully developed drug candidates from their laboratory for the treatment Ebola using EBOV protein structure, such as VP24, VP35, VP40, nucleoprotein, and glycoprotein.
Author: Center For Disease Control
Publisher: International Publications Media Group
ISBN: 1632670119
Category : Medical
Languages : en
Pages : 159
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Book Description
This guidance provides guidelines for handling inquiries and responding to patients with suspected Ebola symptoms; explanation of signs and symptoms of Ebola; prevention and diagnosis of the Ebola Virus Disease (EVD).
Author: Marta Lado
Publisher: Springer
ISBN: 3319948547
Category : Medical
Languages : en
Pages : 192
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Book Description
This current manual gives an overview to management of Ebola Virus Disease outbreaks from a practical point of view. It gives an introduction to the topic, reviews the history and previous outbreaks of Ebola virus disease and gives insight to clinical features of the disease. The major part of the book presents ways of response including screening, isolation and personal protection equipment as well as waste management during disease outbreaks. New therapies and experimental drugs are discussed in further detail. The last part of the volume deals with all aspects of diagnostics and practical laboratory handling of Ebola virus. Dr. Marta Lado is the clinical lead of the King’s Sierra Leone Partnership in country team. She brings together a group of authors aggregating both well-grounded basic knowledge on Ebola virus as well as deep experience with Ebola Virus Disease in the field.
Author: Nicholas G. Evans
Publisher: MIT Press
ISBN: 0262035073
Category : Medical
Languages : en
Pages : 290
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Book Description
Interdisciplinary perspectives on the science, politics, and ethics of the 2013–2015 Ebola virus disease outbreak. The 2013–2015 outbreak of the Ebola virus disease (EVD) was a public health disaster: 28,575 infections and 11,313 deaths (as of October 2015), devastating the countries of Guinea, Liberia, and Sierra Leone; a slow and mismanaged international response; and sensationalistic media coverage, seized upon by politicians to justify wrongheaded policy. And yet there were also promising developments that may improve future responses to infectious disease epidemics: the UN Security Council's first involvement in a public health event; a series of promising clinical treatments and vaccines for EVD; and recognition of the need for a global public health system to deal with epidemics that cross national borders. This volume offers a range of perspectives on these and other lessons learned, with essays on the science, politics, and ethics of the Ebola outbreak. The contributors discuss topics including the virology and management of EVD in both rich and poor nations; the spread of the disease (with an essay by a leader of Médecins Sans Frontières); racist perceptions of West Africa; mainstream and social media responses to Ebola; and the ethical issue of whether to run clinical trials of experimental treatments during an outbreak. Contributors Christian L. Althaus, Daniel G. Bausch, Adia Benton, Michael J. Connor, Jr., Kim Yi Dionne, Nicholas G. Evans, Morenike Oluwatoyin Folayan, Stephen Goldstein, Bridget Haire, Patricia C. Henwood, Kelly Hills, Cyril Ibe, Marjorie Kruvand, Lisa M. Lee, Maimuna S. Majumder, Alexandra L. Phelan, Annette Rid, Cristine Russell, Lara Schwarz, Laura Seay, Michael Selgelid, Tara C. Smith, Armand Sprecher
Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241549602
Category : Medical
Languages : en
Pages : 203
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Book Description
First published in March 2014 under the title "Clinical management of patients with viral haemorrhagic fever: a pocket guide for front-line health workers: interim emergency guidance for West Africa".
Author: Michiel Hofman
Publisher: Oxford University Press
ISBN: 0190624477
Category : Medical
Languages : en
Pages : 305
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Book Description
The Politics of Fear is Médecins sans Frontières's commissioned analysis of the politics surrounding the 2014 Ebola epidemic and response. Comprising eleven topic-based chapters and four eyewitness vignettes from contributors inside and outside MSF (all of whom have been given access to MSF Ebola archives from Guinea, Sierra Leone, and Liberia for research), it aims to provide a politically agnostic account of the defining health event of the 21st century so far, a resource that will inform current opinions and foster effectual, cooperative response to the future epidemics.
