The Ebola Epidemic in West Africa

The Ebola Epidemic in West Africa PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309450063
Category : Medical
Languages : en
Pages : 137

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Book Description
The most recent Ebola epidemic that began in late 2013 alerted the entire world to the gaps in infectious disease emergency preparedness and response. The regional outbreak that progressed to a significant public health emergency of international concern (PHEIC) in a matter of months killed 11,310 and infected more than 28,616. While this outbreak bears some unique distinctions to past outbreaks, many characteristics remain the same and contributed to tragic loss of human life and unnecessary expenditure of capital: insufficient knowledge of the disease, its reservoirs, and its transmission; delayed prevention efforts and treatment; poor control of the disease in hospital settings; and inadequate community and international responses. Recognizing the opportunity to learn from the countless lessons of this epidemic, the National Academies of Sciences, Engineering, and Medicine convened a workshop in March 2015 to discuss the challenges to successful outbreak responses at the scientific, clinical, and global health levels. Workshop participants explored the epidemic from multiple perspectives, identified important questions about Ebola that remained unanswered, and sought to apply this understanding to the broad challenges posed by Ebola and other emerging pathogens, to prevent the international community from being taken by surprise once again in the face of these threats. This publication summarizes the presentations and discussions from the workshop.

The Ebola Epidemic in West Africa

The Ebola Epidemic in West Africa PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309450063
Category : Medical
Languages : en
Pages : 137

Get Book

Book Description
The most recent Ebola epidemic that began in late 2013 alerted the entire world to the gaps in infectious disease emergency preparedness and response. The regional outbreak that progressed to a significant public health emergency of international concern (PHEIC) in a matter of months killed 11,310 and infected more than 28,616. While this outbreak bears some unique distinctions to past outbreaks, many characteristics remain the same and contributed to tragic loss of human life and unnecessary expenditure of capital: insufficient knowledge of the disease, its reservoirs, and its transmission; delayed prevention efforts and treatment; poor control of the disease in hospital settings; and inadequate community and international responses. Recognizing the opportunity to learn from the countless lessons of this epidemic, the National Academies of Sciences, Engineering, and Medicine convened a workshop in March 2015 to discuss the challenges to successful outbreak responses at the scientific, clinical, and global health levels. Workshop participants explored the epidemic from multiple perspectives, identified important questions about Ebola that remained unanswered, and sought to apply this understanding to the broad challenges posed by Ebola and other emerging pathogens, to prevent the international community from being taken by surprise once again in the face of these threats. This publication summarizes the presentations and discussions from the workshop.

Ebola and Marburg Viruses

Ebola and Marburg Viruses PDF Author: Hans-Dieter Klenk
Publisher: Garland Science
ISBN: 9780954523237
Category : Cell physiology
Languages : en
Pages : 392

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Book Description
The Ebola and Marburg viruses are a pair of filoviruses that are among the most lethal hemorrhagic viruses on the planet. The authors present a review of past and current research into these pathogens, including 12 papers addressing the structure of the viral proteins; genomic replication; molecular mechanisms of entry; pathogenesis in nonhuman primates, guinea pigs, and mice; virus modulation of innate immunity; and cellular and molecular mechanisms of Ebola pathogenicity and related approaches to vaccine development.

Guidelines for the management of pregnant and breastfeeding women in the context of Ebola virus disease

Guidelines for the management of pregnant and breastfeeding women in the context of Ebola virus disease PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240001387
Category : Medical
Languages : en
Pages : 52

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Book Description
The Democratic Republic of Congo is currently experiencing the second largest Ebola outbreak in history, following a 2014-2016 outbreak in western Africa that had an estimated 28,000 cases. Investigational treatment and vaccination trials are ongoing, but data in the context of pregnancy and breastfeeding are limited. A paucity of scientific evidence exists on how to best treat pregnant or breastfeeding women with suspected or confirmed Ebola virus disease (EVD). Historical reports suggest that, among women who acquire EVD during pregnancy, there is increased mortality and morbidity, and a near 100% rate of adverse pregnancy outcomes. To save the lives of mothers and their babies, mitigate complications, and limit the spread of disease, it is critical that recommendations are made on the prevention, treatment, and surveillance of women who are exposed to EVD, acquire EVD during pregnancy or breastfeeding, or survive EVD with ongoing pregnancies. These guidelines are the first to provide such recommendations.

Ebola Prevention and Control

Ebola Prevention and Control PDF Author: Angela Dramowski
Publisher: Bettercare
ISBN: 9781920218867
Category :
Languages : en
Pages : 166

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Book Description
Ebola Prevention and Control is a crucial guide to managing, preventing and controlling Ebola and other viral haemorrhagic fevers, especially in resource-limited settings. Chapters cover: - Virology and epidemiology - Patient management - Protection of healthcare workers - Support services and documentation - Communication and community engagement Ebola Prevention and Control is suited to healthcare workers, managers and administrators tasked with preventing, controlling and managing outbreaks of viral haemorrhagic diseases.

Guidelines on Core Components of Infection Prevention and Control Programmes at the National and Acute Health Care Facility Level

Guidelines on Core Components of Infection Prevention and Control Programmes at the National and Acute Health Care Facility Level PDF Author: World Health Organization
Publisher:
ISBN: 9789241549929
Category : Medical
Languages : en
Pages : 92

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Book Description
Health care-associated infections (HAI) are one of the most common adverse events in care delivery and a major public health problem with an impact on morbidity, mortality and quality of life. At any one time, up to 7% of patients in developed and 10% in developing countries will acquire at least one HAI. These infections also present a significant economic burden at the societal level. However, a large percentage are preventable through effective infection prevention and control (IPC) measures. These new guidelines on the core components of IPC programmes at the national and facility level will enhance the capacity of Member States to develop and implement effective technical and behaviour modifying interventions. They form a key part of WHO strategies to prevent current and future threats from infectious diseases such as Ebola, strengthen health service resilience, help combat antimicrobial resistance (AMR) and improve the overall quality of health care delivery. They are also intended to support countries in the development of their own national protocols for IPC and AMR action plans and to support health care facilities as they develop or strengthen their own approaches to IPC. These are the first international evidence-based guidelines on the core components of IPC programmes. These new WHO guidelines are applicable for any country and suitable to local adaptations, and take account of the strength of available scientific evidence, the cost and resource implications, and patient values and preferences.

Disease Control Priorities, Third Edition (Volume 9)

Disease Control Priorities, Third Edition (Volume 9) PDF Author: Dean T. Jamison
Publisher: World Bank Publications
ISBN: 1464805288
Category : Medical
Languages : en
Pages : 426

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Book Description
As the culminating volume in the DCP3 series, volume 9 will provide an overview of DCP3 findings and methods, a summary of messages and substantive lessons to be taken from DCP3, and a further discussion of cross-cutting and synthesizing topics across the first eight volumes. The introductory chapters (1-3) in this volume take as their starting point the elements of the Essential Packages presented in the overview chapters of each volume. First, the chapter on intersectoral policy priorities for health includes fiscal and intersectoral policies and assembles a subset of the population policies and applies strict criteria for a low-income setting in order to propose a "highest-priority" essential package. Second, the chapter on packages of care and delivery platforms for universal health coverage (UHC) includes health sector interventions, primarily clinical and public health services, and uses the same approach to propose a highest priority package of interventions and policies that meet similar criteria, provides cost estimates, and describes a pathway to UHC.

CDC Guidance on Ebola Virus (EVD)

CDC Guidance on Ebola Virus (EVD) PDF Author: Center For Disease Control
Publisher: International Publications Media Group
ISBN: 1632670119
Category : Medical
Languages : en
Pages : 159

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Book Description
This guidance provides guidelines for handling inquiries and responding to patients with suspected Ebola symptoms; explanation of signs and symptoms of Ebola; prevention and diagnosis of the Ebola Virus Disease (EVD).

Ebola Virus Disease (EVD)

Ebola Virus Disease (EVD) PDF Author: Hilaire Verreau
Publisher:
ISBN: 9781536162912
Category : Ebola virus disease
Languages : en
Pages : 118

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Book Description
To mitigate the spread of the rare and deadly disease Ebola, Ebola Virus Disease (EVD): Outbreaks, Control and Prevention Strategies begins with the proposition of a mathematical model with vital dynamics and two preventive measures: quarantine and isolation. Humanitarian issues in Ebola prevention and control are explored, as well as the cultural practices and social norms during outbreaks. Additionally, some innovative approaches in the humanitarian response to prevention and control are discussed. The authors expose the dilemma Ebola poses to within the healthcare system, where healthcare providers are caught between the over-arching quest for self-preservation from a highly virulent disease and the professional demand of prioritising the interests of the patients over self. In conclusion, the authors describe successfully developed drug candidates from their laboratory for the treatment Ebola using EBOV protein structure, such as VP24, VP35, VP40, nucleoprotein, and glycoprotein.

Global Management of Infectious Disease After Ebola

Global Management of Infectious Disease After Ebola PDF Author: Sam F. Halabi
Publisher: Oxford University Press
ISBN: 0190604905
Category : Medical
Languages : en
Pages : 256

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Book Description
The 2014-2015 Ebola outbreak in West Africa shocked the world with its devastation and its rapid migration to multiple continents. As the systems meant to respond to this sort of epidemic failed, the disease exposed not just weaknesses in international infectious disease surveillance and management, but the failures of governments, humanitarian organizations, and international institutions to handle the legal, ethical, and economic questions that arose with an event of this scale. GLOBAL MANAGEMENT OF INFECTIOUS DISEASE AFTER EBOLA unites the insights of Ebola's first responders with those the world's foremost experts in law, economics, vaccine development, and global migration to identify missed opportunities from the Ebola crisis -- and to apply these lessons to emerging infectious disease threats. Framed with critical discussions of both the global health financing infrastructures that precipitated the response and the ethical and human rights dilemmas that resulted from it, this volume is much more than postmortem to an outbreak: it is a vital, sometimes damning examination of where we've been and where we're going in the face of emerging infectious diseases.

Ebola

Ebola PDF Author: Joseph R. Masci
Publisher: CRC Press
ISBN: 1351646168
Category : Medical
Languages : en
Pages : 276

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Book Description
Ebola: Clinical Patterns, Public Health Concerns is a concise description and discussion of the Ebola virus and disease. The intended audience is medical practitioners, including those working in endemic areas as well as health-facility planners and public health practitioners. The book fills an important gap between large texts covering not only Ebola but other hemorrhagic fever viruses and brief pamphlet-style publications on the public health aspects of the infection. In light of the recent large outbreak in West Africa, this book is a part of the developing foundation needed to deal with emerging diseases.