Ebola and Marburg treatment centres

Ebola and Marburg treatment centres PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240090088
Category : Medical
Languages : en
Pages : 136

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Book Description
This manual addresses the design and construction of healthcare facilities supporting the response to Ebola and Marburg (E&M) disease outbreaks, particularly in treatment centres (TCs). It provides technical guidance, minimum requirements, practical tools and layout examples, and references for planning, designing, building, and operating healthcare facilities (TCs and others) to respond to E&M disease outbreaks in low– and middle-income contexts and resource-limited settings. The manual complements other World Health Organization (WHO) literature and contributes to the standardization of facility design and operation for safe and humane care and treatment of patients.

Ebola and Marburg treatment centres

Ebola and Marburg treatment centres PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240090088
Category : Medical
Languages : en
Pages : 136

Get Book Here

Book Description
This manual addresses the design and construction of healthcare facilities supporting the response to Ebola and Marburg (E&M) disease outbreaks, particularly in treatment centres (TCs). It provides technical guidance, minimum requirements, practical tools and layout examples, and references for planning, designing, building, and operating healthcare facilities (TCs and others) to respond to E&M disease outbreaks in low– and middle-income contexts and resource-limited settings. The manual complements other World Health Organization (WHO) literature and contributes to the standardization of facility design and operation for safe and humane care and treatment of patients.

Ebola and Marburg Viruses

Ebola and Marburg Viruses PDF Author: Hans-Dieter Klenk
Publisher: Garland Science
ISBN: 9780954523237
Category : Medical
Languages : en
Pages : 392

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Book Description
The Ebola and Marburg viruses are a pair of filoviruses that are among the most lethal hemorrhagic viruses on the planet. The authors present a review of past and current research into these pathogens, including 12 papers addressing the structure of the viral proteins; genomic replication; molecular mechanisms of entry; pathogenesis in nonhuman primates, guinea pigs, and mice; virus modulation of innate immunity; and cellular and molecular mechanisms of Ebola pathogenicity and related approaches to vaccine development.

Clinical Management of Patients with Viral Haemorrhagic Fever

Clinical Management of Patients with Viral Haemorrhagic Fever PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9241549602
Category : Medical
Languages : en
Pages : 203

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Book Description
First published in March 2014 under the title "Clinical management of patients with viral haemorrhagic fever: a pocket guide for front-line health workers: interim emergency guidance for West Africa".

The Hot Zone

The Hot Zone PDF Author: Richard Preston
Publisher: Corgi
ISBN: 9780552143035
Category : Ebola virus disease
Languages : en
Pages : 383

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Book Description
Imagine a killer with the infectiousness of the common cold and power of the Black Death. Imagine something so deadly that it wipes out 90% of those it touches. Imagine an organism against which there is no defence. But you don't need to imagine. Such a killer exists: it is a virus and its name is Ebola. The Hot Zone tells what happens when the unthinkable becomes reality: when a deadly virus, from the rain forests of Africa, crosses continents and infects a monkey house ten miles from the White House. Ebola is that reality. It has the power to decimate the world's population. Try not to panic. It will be back. There is nothing you can do...

Filoviruses

Filoviruses PDF Author: Jens Kuhn
Publisher: Springer Science & Business Media
ISBN: 3211694951
Category : Medical
Languages : en
Pages : 410

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Book Description
This is the first comprehensive review of the world literature on filovirus research and provides the most extensive bibliography of the subject yet published. There is special emphasis on foreign literature that has never been summarized. Every aspect of filovirus research, including their history, epidemiology, clinical picture, pathology, molecular biology, and political aspects are reviewed in detail.

Nonhuman Primates I

Nonhuman Primates I PDF Author: Thomas C. Jones
Publisher: Springer
ISBN: 9783642849084
Category : Medical
Languages : en
Pages : 0

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Book Description
The International Life Sciences Institute (ILSI) was estab lished in 1978 to stimulate and support scientific research and educational programs related to nutrition, toxicology, and food safety, and to encourage cooperation in these programs among scientists in universities, industry, and government agencies to assist in the resolution of health and safety issues. To supplement and enhance these efforts, ILSI has made a major commitment to supporting programs to harmonize toxicologic testing, to advance a more uniform interpreta tion of bioassay results worldwide, to promote a common understanding of lesion classifications, and to encourage wide discussion of these topics among scientists. The Mo nographs on the Pathology of Laboratory Animals are de signed to facilitate communication among those involved in the safety testing of foods, drugs, and chemicals. The complete set will cover all organ systems and is intended for use by pathologists, toxicologists, and others con cerned with evaluating toxicity and carcinogenicity stu dies. The international nature of the project - as reflected in the composition of the editorial board and the diversity of the authors and editors -strengthens our expectations that understanding and cooperation will be improved worldwide through the series. Alex Malaspina President International Life Sciences Institute Preface This book, on Nonhuman Primates, is the eleventh volume of a set pre pared under the sponsorship of the International Life Sciences Institute (ILSI).

Marburg- and Ebolaviruses

Marburg- and Ebolaviruses PDF Author: Elke Mühlberger
Publisher: Springer
ISBN: 3319689487
Category : Medical
Languages : en
Pages : 456

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Book Description
This volume provides an overview of recent advances in our understanding of the biology of marburg- and ebolaviruses. It focuses on four essential areas: 1) ecology, outbreaks and clinical management, 2) disease, pathogenesis and protection, 3) virus replication inside the cell, and 4) molecular tools for virus study and taxonomy. For 50 years, these viruses have spilled over sporadically and without warning from their wildlife reservoirs, often causing major outbreaks and high fatalities. The consequences can be devastating, with a clear potential for global reach, as demonstrated by the 2013 West African outbreak of Ebola virus, which led to over 28,000 reported cases across three continents and more than 11,000 deaths. Given the international threat posed by these viruses, the pace and scope of basic research have also greatly intensified, ranging from studies of virus emergence, epidemiology, antiviral countermeasures and human disease to detailed mechanistic studies of virus entry, replication, virion assembly and protein structure. Written by internationally respected experts, this book will appeal to a wide audience and be a valuable resource for basic researchers, clinicians and advanced students alike.

Marburg Virus Disease

Marburg Virus Disease PDF Author: G. A. Martini
Publisher: Springer Science & Business Media
ISBN: 3662015935
Category : Medical
Languages : en
Pages : 237

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Book Description
In the late summer of 1967, several patients suffering from a severe disease were admitted to the Department of Medicine of the Marburg University. It soon became obvious that the illness was a hitherto unknown infectious disease. The number of afflicted patients increased to 23. Several cases were observed in Frankfurt/Main at the same time and, some weeks later also in Belgrade, Yugo slavia. Common to all the patients was previous contact with the blood or tissues of Cercopithecus aethiops, the vervet monkey. Altogether 31 people became ill and 7 died. It was soon apparent that the infectious agent was neither bacterial nor rickettsial in origin but that a viral etiology was probable. Most of the known viral diseases were excluded and the infectious agent was shown to be a hitherto unknown virus with many peculiar characteristics: it infects guinea pigs but not adult mice and is larger than known viruses and of different shape. This agent was called the "Marburg virus" since most of the cases had occurred in Marburg and the greater part of the laboratory work leading to the detection of the virus was performed in Marburg.

Guidelines for the management of pregnant and breastfeeding women in the context of Ebola virus disease

Guidelines for the management of pregnant and breastfeeding women in the context of Ebola virus disease PDF Author: World Health Organization
Publisher: World Health Organization
ISBN: 9240001387
Category : Medical
Languages : en
Pages : 52

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Book Description
The Democratic Republic of Congo is currently experiencing the second largest Ebola outbreak in history, following a 2014-2016 outbreak in western Africa that had an estimated 28,000 cases. Investigational treatment and vaccination trials are ongoing, but data in the context of pregnancy and breastfeeding are limited. A paucity of scientific evidence exists on how to best treat pregnant or breastfeeding women with suspected or confirmed Ebola virus disease (EVD). Historical reports suggest that, among women who acquire EVD during pregnancy, there is increased mortality and morbidity, and a near 100% rate of adverse pregnancy outcomes. To save the lives of mothers and their babies, mitigate complications, and limit the spread of disease, it is critical that recommendations are made on the prevention, treatment, and surveillance of women who are exposed to EVD, acquire EVD during pregnancy or breastfeeding, or survive EVD with ongoing pregnancies. These guidelines are the first to provide such recommendations.

The Ebola Epidemic in West Africa

The Ebola Epidemic in West Africa PDF Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
ISBN: 0309450063
Category : Medical
Languages : en
Pages : 137

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Book Description
The most recent Ebola epidemic that began in late 2013 alerted the entire world to the gaps in infectious disease emergency preparedness and response. The regional outbreak that progressed to a significant public health emergency of international concern (PHEIC) in a matter of months killed 11,310 and infected more than 28,616. While this outbreak bears some unique distinctions to past outbreaks, many characteristics remain the same and contributed to tragic loss of human life and unnecessary expenditure of capital: insufficient knowledge of the disease, its reservoirs, and its transmission; delayed prevention efforts and treatment; poor control of the disease in hospital settings; and inadequate community and international responses. Recognizing the opportunity to learn from the countless lessons of this epidemic, the National Academies of Sciences, Engineering, and Medicine convened a workshop in March 2015 to discuss the challenges to successful outbreak responses at the scientific, clinical, and global health levels. Workshop participants explored the epidemic from multiple perspectives, identified important questions about Ebola that remained unanswered, and sought to apply this understanding to the broad challenges posed by Ebola and other emerging pathogens, to prevent the international community from being taken by surprise once again in the face of these threats. This publication summarizes the presentations and discussions from the workshop.