Brain Metastases

Brain Metastases PDF Author: Jeffrey Raizer
Publisher: Springer Science & Business Media
ISBN: 0387692215
Category : Medical
Languages : en
Pages : 240

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Book Description
Brain metastases are the most dreaded complication of systemic cancer, affecting some 170,000 people a year, a far greater incidence than primary brain tumors. This book presents current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neurosurgeons, radiation oncologists, medical oncologists, and neuron-oncologists, and as an overview for physicians in training.

Brain Metastases

Brain Metastases PDF Author: Jeffrey Raizer
Publisher: Springer Science & Business Media
ISBN: 0387692215
Category : Medical
Languages : en
Pages : 240

Get Book Here

Book Description
Brain metastases are the most dreaded complication of systemic cancer, affecting some 170,000 people a year, a far greater incidence than primary brain tumors. This book presents current information on the presentation and management of patients with brain metastases, providing available data, giving guidelines that can be applied in day to day practice, updated information for neurosurgeons, radiation oncologists, medical oncologists, and neuron-oncologists, and as an overview for physicians in training.

Advances in Cancer Research

Advances in Cancer Research PDF Author:
Publisher: Elsevier
ISBN: 0080490220
Category : Medical
Languages : en
Pages : 297

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Book Description
Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here once again, outstanding and original reviews are presented. - New Paradigms for the Treatment of Cancer: The Role of Anti-aiogenesis Agents - The Hepatocyte Growth Factor/Met Pathway in Development, Tumorigenesis, and B-Cell Differentiation - Clinical Targets for Anti-metastasis Therapy - Animal Models of Melanoma: Recent Advances and Future Prospects - The Indispensable Role of Microenvironment in the Natural History of Low-Grade B-Cell Neoplasms - Epstein-Barr Virus Latency: LMP2, a Regulator or Means for Epstein-Barr Birus - Biochemistry and Pathological Importance of Mucin-Associated Antigens in Gastrointenstinal Neoplasia - Studies on Polyomavirus Persistence and Polyomavirus-Induced Tumor Development in Relation to the Immune System

Journal of the National Cancer Institute

Journal of the National Cancer Institute PDF Author:
Publisher:
ISBN:
Category : Cancer
Languages : en
Pages : 1032

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Book Description


Withrow and MacEwen's Small Animal Clinical Oncology

Withrow and MacEwen's Small Animal Clinical Oncology PDF Author: Stephen J. Withrow
Publisher: Elsevier Health Sciences
ISBN: 0721605583
Category : Medical
Languages : en
Pages : 863

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Book Description
Focusing on cancer in dogs and cats, this extensively updated 4th edition provides comprehensive coverage of the latest advances in clinical oncology, including chemotherapy, surgical oncology, and diagnostic techniques. Ideal for students, practitioners, and those involved in academic research, this book's full-color images and user-friendly format provide quick and easy access to today's most important information on cancer in the small animal patient. Full-color format throughout and full-color illustrations make information more accessible and provide accurate representations of clinical appearance.Chapters are clustered into four major sections: The Biology and Pathogenesis of Cancer, Diagnostic Procedures for the Cancer Patient, Therapeutic Modalities for the Cancer Patient, and Specific Malignancies in the Small Animal Patient.The consistent format includes incidence and risk factors, pathology, natural behavior of tumors, history and clinical signs, diagnostic techniques and workup, treatment options, and prognosis for specific malignancies in the small animal cancer patient.Features cutting edge information on the complications of cancer, pain management, and the latest treatment modalities. The latest information on the etiology of cancer, including genetic, chemical, physical, and hormonal factors, as well as cancer-causing viruses.Coverage of molecular-targeted therapy of cancer, plus new and emerging therapeutic techniques.New information on molecular diagnostic procedures for the cancer patient.The latest diagnostic imaging techniques in clinical oncology.Discussions of compassion and supportive care, from chronic pain management and nutrition to end-of-life issues and grief support.

Withrow and MacEwen's Small Animal Clinical Oncology - E-Book

Withrow and MacEwen's Small Animal Clinical Oncology - E-Book PDF Author: David M. Vail
Publisher: Elsevier Health Sciences
ISBN: 0323594972
Category : Medical
Languages : en
Pages : 865

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Book Description
**Selected for Doody's Core Titles® 2024 with "Essential Purchase" designation in Veterinary Medicine** Considered the definitive reference on canine and feline oncology, Withrow & MacEwen's Small Animal Clinical Oncology, 6th Edition focuses on the most effective, cutting-edge techniques. This comprehensive textbook gives you a complete understanding of cancer in dogs and cats — what it is, how to diagnose it, and how to treat many of the most common cancers encountered in clinical practice today. The thoroughly updated sixth edition includes information on the complications of cancer, pain management, and the latest treatment modalities — preparing general practitioners to diagnose and treat pets rather than referring them to a specialist. With important updates on recently approved and in-development drugs, and new co-authors adding their own unique perspectives, this user-friendly text is a must-have resource for current, evidence-based therapeutic strategies on canine and feline oncology. - Cutting-edge information on the complications of cancer, pain management, and the latest treatment modalities prepares you to diagnose and treat pets with cancer rather than refer cases to a specialist. - Each contributor is a recognized expert in his or her specialty, reflecting the most current information by highly respected experts in the field of veterinary oncology. - Full-color format provides you with accurate visual depictions of specific diseases and procedures, enhances visual appeal, and is used functionally in tables and boxes to highlight key information. - A systems approach to the diagnosis and management of cancer facilitates access to information about the many malignancies affecting small animal patients. - Discussion of compassion and supportive care for the management of pain, nutritional needs, and grief includes methods for handling the pet's pain and nutritional complications as well as the pet owner's grief when treatment is not successful. - Comprehensive references at the end of each chapter and topic ensures you can be confident the information provided is accurate and up to date. - Helpful drug formularies provide quick access to information on indications, toxicities, and recommended dosages for chemotherapeutic and analgesic drugs used in cancer treatment. - Chemotherapy protocols are included when case studies prove clinical efficacy. - Information on the best interventional techniques is quickly accessible all in one chapter. - Nearly 400 color images provide accurate depictions of specific diseases and procedures. - Focus on the most effective treatment options saves time by emphasizing proven treatment options that have been vetted by experts in the field. - NEW! Expert co-authors and contributors bring a valuable perspective with research experience. - NEW! Thoroughly UPDATED content includes important updates on recently approved and in-development veterinary cancer drugs, and critical advances in radiation delivery.

Journal of Cell Science

Journal of Cell Science PDF Author:
Publisher:
ISBN:
Category : Cytology
Languages : en
Pages : 690

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Book Description


Angiogenesis Assays

Angiogenesis Assays PDF Author: Carolyn A. Staton
Publisher: John Wiley & Sons
ISBN: 047002934X
Category : Medical
Languages : en
Pages : 410

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Book Description
Angiogenesis, the development of new blood vessels from the existing vasculature, is essential for physiological growth and over 18,000 research articles have been published describing the role of angiogenesis in over 70 different diseases, including cancer, diabetic retinopathy, rheumatoid arthritis and psoriasis. One of the most important technical challenges in such studies has been finding suitable methods for assessing the effects of regulators of eh angiogenic response. While increasing numbers of angiogenesis assays are being described both in vitro and in vivo, it is often still necessary to use a combination of assays to identify the cellular and molecular events in angiogenesis and the full range of effects of a given test protein. Although the endothelial cell - its migration, proliferation, differentiation and structural rearrangement - is central to the angiogenic process, it is not the only cell type involved. the supporting cells, the extracellular matrix and the circulating blood with its cellular and humoral components also contribute. In this book, experts in the use of a diverse range of assays outline key components of these and give a critical appraisal of their strengths and weaknesses. Examples include assays for the proliferation, migration and differentiation of endothelial cells in vitro, vessel outgrowth from organ cultures, assessment of endothelial and mural cell interactions, and such in vivo assays as the chick chorioallantoic membrane, zebrafish, corneal, chamber and tumour angiogenesis models. These are followed by a critical analysis of the biological end-points currently being used in clinical trials to assess the clinical efficacy of anti-angiogenic drugs, which leads into a discussion of the direction future studies should take. This valuable book is of interest to research scientists currently working on angiogenesis in both the academic community and in the biotechnology and pharmaceutical industries. Relevant disciplines include cell and molecular biology, oncology, cardiovascular research, biotechnology, pharmacology, pathology and physiology.

Metastatic Cancer: Clinical and Biological Perspectives

Metastatic Cancer: Clinical and Biological Perspectives PDF Author: Rahul Jandial
Publisher: CRC Press
ISBN: 9781587066597
Category : Medical
Languages : en
Pages : 312

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Book Description
Most cancer deaths are a result of metastasis. The spread of a primary tumor to colonize neighboring and distant organs is the relentless endgame that defines the neoplastic process. Patients who have been diagnosed with cancer are treated to prevent both the recurrence of the tumor at the site of origin and metastasis that would re-stage them as advanced stage IV cancer. Historically and still with some types of cancer, stage IV is perceived by patients as “terminal.” Fortunately, recent molecular therapies have extended the lives of patients with advanced cancer and reassuringly people living with metastatic disease increasingly visit our clinics. What is the path forward? Given that the consilience of science and medicine is a dynamic art from which therapies arise, it would be misguided to consider any single work adequate at capturing the horizon for research. So with humility we constructed this text as primer for scientists. It begins with a broad introduction to the clinical management of common cancers. This is intended to serve as a foundation for investigators to consider when developing basic science hypotheses. Unquestionably, medical and surgical care of cancer patients reveals biology and dictates how novel therapeutics will ultimately be evaluated in clinical trials. The second section of this text offers provocative and evolving insights that underscore the breadth of science involved in the elucidation of cancer metastasis biology. The text concludes with information that integrates scientific and clinical foundations to highlight translational research. This book serves as a framework for scientists to conceptualize clinical and translational knowledge on the complexity of disease that is metastatic cancer.

Biomechanics in Oncology

Biomechanics in Oncology PDF Author: Cheng Dong
Publisher: Springer
ISBN: 3319952943
Category : Medical
Languages : en
Pages : 378

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Book Description
This book covers multi-scale biomechanics for oncology, ranging from cells and tissues to whole organ. Topics covered include, but not limited to, biomaterials in mechano-oncology, non-invasive imaging techniques, mechanical models of cell migration, cancer cell mechanics, and platelet-based drug delivery for cancer applications. This is an ideal book for graduate students, biomedical engineers, and researchers in the field of mechanobiology and oncology. This book also: Describes how mechanical properties of cancer cells, the extracellular matrix, tumor microenvironment and immuno-editing, and fluid flow dynamics contribute to tumor progression and the metastatic process Provides the latest research on non-invasive imaging, including traction force microscopy and brillouin confocal microscopy Includes insight into NCIs’ role in supporting biomechanics in oncology research Details how biomaterials in mechano-oncology can be used as a means to tune materials to study cancer

The Biology of Skeletal Metastases

The Biology of Skeletal Metastases PDF Author: Evan T. Keller
Publisher: Springer Science & Business Media
ISBN: 9781402077494
Category : Medical
Languages : en
Pages : 378

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Book Description
- National Cancer Institure Budget is encouraging research in order to develop a better understanding of metastasis of cancer to the bone - Provides the reader with comprehensive reviews written by well known experts on related topics