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Author: Thomas Lecuit
Publisher: Collège de France
ISBN: 2722605600
Category : Science
Languages : en
Pages : 32
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Book Description
How can we explain the fundamental paradox of living matter, which combines stability and robustness of form with constant internal dynamics? It is not only the genetic information contained in every cell, but also numerous stochastic biomolecular processes that are at work in morphogenesis. In addition, the shaping of an organism is driven by mechanical forces that operate within and between cells, across tissues and organs. The dynamics of morphogenesis is a self-organized process that emerges from biological control and physical constraints at all scales. Its study is currently bringing together a fast-growing interdisciplinary community that observes, analyses and models living organisms.
Author: Thomas Lecuit
Publisher: Collège de France
ISBN: 2722605600
Category : Science
Languages : en
Pages : 32
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Book Description
How can we explain the fundamental paradox of living matter, which combines stability and robustness of form with constant internal dynamics? It is not only the genetic information contained in every cell, but also numerous stochastic biomolecular processes that are at work in morphogenesis. In addition, the shaping of an organism is driven by mechanical forces that operate within and between cells, across tissues and organs. The dynamics of morphogenesis is a self-organized process that emerges from biological control and physical constraints at all scales. Its study is currently bringing together a fast-growing interdisciplinary community that observes, analyses and models living organisms.
Author: J. Ricard
Publisher: Elsevier
ISBN: 0080860958
Category : Science
Languages : en
Pages : 369
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Book Description
The aim of this book is to show how supramolecular complexity of cell organization can dramatically alter the functions of individual macromolecules within a cell. The emergence of new functions which appear as a consequence of supramolecular complexity, is explained in terms of physical chemistry. The book is interdisciplinary, at the border between cell biochemistry, physics and physical chemistry. This interdisciplinarity does not result in the use of physical techniques but from the use of physical concepts to study biological problems. In the domain of complexity studies, most works are purely theoretical or based on computer simulation. The present book is partly theoretical, partly experimental and theory is always based on experimental results. Moreover, the book encompasses in a unified manner the dynamic aspects of many different biological fields ranging from dynamics to pattern emergence in a young embryo. The volume puts emphasis on dynamic physical studies of biological events. It also develops, in a unified perspective, this new interdisciplinary approach of various important problems of cell biology and chemistry, ranging from enzyme dynamics to pattern formation during embryo development, thus paving the way to what may become a central issue of future biology.
Author: Jan Walleczek
Publisher: Cambridge University Press
ISBN: 9780521624367
Category : Science
Languages : en
Pages : 34
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Book Description
Collection of articles on the impact of nonlinear science on biology.
Author: Claire Bidart
Publisher: Cambridge University Press
ISBN: 1108841430
Category : Reference
Languages : en
Pages : 339
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Book Description
Innovative study examining how relationships and personal networks evolve throughout life, and how these connect individuals and society.
Author: Charles Fillmore
Publisher:
ISBN: 9781618954367
Category : Self-Help
Languages : en
Pages : 216
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Book Description
Charles Sherlock Fillmore (August 22, 1854 - July 5, 1948) founded Unity, a church within the New Thought movement, with his wife, Myrtle Page Fillmore, in 1889. He became known as an American mystic for his contributions to spiritualist interpretations of biblical Scripture. He was born in St. Cloud, Minnesota on August 22, 1854. An ice skating accident when he was ten broke Fillmore's hip and left him with lifelong disabilities. In his early years, despite little formal education, he studied Shakespeare, Tennyson, Emerson and Lowell as well as works on spiritualism, Eastern religions, and metaphysics. He met his future wife, Mary Caroline "Myrtle" Page, in Denison, Texas in the mid-1870s. After losing his job there, he moved to Gunnison, Colorado where he worked at mining and real estate. He married Myrtle in Clinton, Missouri on March 29, 1881 and the newlyweds moved to Pueblo, Colorado, where Charles established a real estate business with the brother-in-law of Nona Lovell Brooks, who was later to found the Church of Divine Science. After the births of their first two sons, Lowell Page Fillmore and Waldo Rickert Fillmore, the family moved to Kansas City, Missouri. Two years later, in 1886, Charles and Myrtle attended New Thought classes held by Dr. E. B. Weeks. Myrtle subsequently recovered from chronic tuberculosis and attributed her recovery to her use of prayer and other methods learned in Weeks's classes. Subsequently, Charles began to heal from his childhood accident, a development which he too attributed to following this philosophy. Charles Fillmore became a devoted student of philosophy and religion. In 1889, Charles and Myrtle began publication of a new periodical, 'Modern Thought', notable among other things as the first publication to accept for publication the writings of the then 27-year-old New Thought pioneer William Walker Atkinson. In 1890, they announced a prayer group that would later be called 'Silent Unity'. In 1891, Fillmore's 'Unity' magazine was first published. Dr. H. Emilie Cady published 'Lessons in Truth' in the new magazine. This material later was compiled and published in a book by the same name, which served as a seminal work of the Unity Church. Although Charles had no intention of making Unity into a denomination, his students wanted a more organized group. He and his wife were among the first ordained Unity ministers in 1906. Charles and Myrtle Fillmore operated the Unity organizations from a campus near downtown Kansas City. Myrtle Fillmore died in 1931. Charles remarried in 1933 to Cora G. Dedrick who was a collaborator on his later writings. Charles Fillmore died in 1948. Unity continued, growing into a worldwide movement; Unity World Headquarters at Unity Village and Unity Worldwide Ministries are the organizations of the movement. (wikipedia.org)
Author: Kim Sneppen
Publisher: Cambridge University Press
ISBN: 1107061903
Category : Science
Languages : en
Pages : 353
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Book Description
An overview of current models of biological systems, reflecting the major advances that have been made over the past decade.
Author: Charles Fillmore
Publisher: Cosimo, Inc.
ISBN: 1605209341
Category : Self-Help
Languages : en
Pages : 222
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Book Description
American mystic CHARLES FILLMORE (1854-1948) was a founder of Unity Church, part of the early "New Age" movement called New Thought that was popular in the late 19th and early 20th centuries. Unity adheres to a "positive, practical Christianity," and this 1940 edition embodies that philosophy: it preaches that poverty is a sin, and that God wants us to be rich...a strain that has been picked up by some modern fundamentalist preachers in a way not entirely faithful to Fillmore's beliefs. Fillmore's lessons encompass... [ Spiritual Substance, the Fundamental Basis of the Universe [ Spiritual Mind, the Omnipresent Directive Principle of Prosperity [ Faith in the Invisible Substance, the Key to Demonstration [ Man, the Inlet and Outlet of Divine Mind [ The Law That Governs the Manifestation of Supply [ Wealth of Mind Expresses Itself in Riches [ God Has Provided Prosperity for Every Home [ God Will Pay Your Debts [ Tithing, the Road to Prosperity [ Right Giving, the Key to Abundant Receiving [ Laying Up Treasures [ Overcoming the Thought of Lack
Author: Richard F. Lovelace
Publisher: InterVarsity Press
ISBN: 0830854932
Category : Religion
Languages : en
Pages : 459
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Book Description
In this expanded edition of a classic work of spiritual theology, historian Richard Lovelace presents a history of spiritual renewals in light of biblical models. With scholarly and pastoral insight, he offers a powerful vision of renewal that can unify various models across traditions, combining individual and corporate spirituality, social activism, and evangelism.
Author: Martin A. Nowak
Publisher: Harvard University Press
ISBN: 0674417755
Category : Science
Languages : en
Pages : 390
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Book Description
At a time of unprecedented expansion in the life sciences, evolution is the one theory that transcends all of biology. Any observation of a living system must ultimately be interpreted in the context of its evolution. Evolutionary change is the consequence of mutation and natural selection, which are two concepts that can be described by mathematical equations. Evolutionary Dynamics is concerned with these equations of life. In this book, Martin A. Nowak draws on the languages of biology and mathematics to outline the mathematical principles according to which life evolves. His work introduces readers to the powerful yet simple laws that govern the evolution of living systems, no matter how complicated they might seem. Evolution has become a mathematical theory, Nowak suggests, and any idea of an evolutionary process or mechanism should be studied in the context of the mathematical equations of evolutionary dynamics. His book presents a range of analytical tools that can be used to this end: fitness landscapes, mutation matrices, genomic sequence space, random drift, quasispecies, replicators, the Prisoner’s Dilemma, games in finite and infinite populations, evolutionary graph theory, games on grids, evolutionary kaleidoscopes, fractals, and spatial chaos. Nowak then shows how evolutionary dynamics applies to critical real-world problems, including the progression of viral diseases such as AIDS, the virulence of infectious agents, the unpredictable mutations that lead to cancer, the evolution of altruism, and even the evolution of human language. His book makes a clear and compelling case for understanding every living system—and everything that arises as a consequence of living systems—in terms of evolutionary dynamics.
Author: Noriko Hiroi
Publisher: Frontiers Media SA
ISBN: 2889452131
Category :
Languages : en
Pages : 138
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Book Description
With the emergence of Systems Biology, there is a greater realization that the whole behavior of a living system may not be simply described as the sum of its elements. To represent a living system using mathematical principles, practical quantities with units are required. Quantities are not only the bridge between mathematical description and biological observations; they often stand as essential elements similar to genome information in genetics. This important realization has greatly rejuvenated research in the area of Quantitative Biology. Because of the increased need for precise quantification, a new era of technological development has opened. For example, spatio-temporal high-resolution imaging enables us to track single molecule behavior in vivo. Clever artificial control of experimental conditions and molecular structures has expanded the variety of quantities that can be directly measured. In addition, improved computational power and novel algorithms for analyzing theoretical models have made it possible to investigate complex biological phenomena. This research topic is organized on two aspects of technological advances which are the backbone of Quantitative Biology: (i) visualization of biomolecules, their dynamics and function, and (ii) generic technologies of model optimization and numeric integration. We have also included articles highlighting the need for new quantitative approaches to solve some of the long-standing cell biology questions. In the first section on visualizing biomolecules, four cutting-edge techniques are presented. Ichimura et al. provide a review of quantum dots including their basic characteristics and their applications (for example, single particle tracking). Horisawa discusses a quick and stable labeling technique using click chemistry with distinct advantages compared to fluorescent protein tags. The relatively small physical size, stability of covalent bond and simple metabolic labeling procedures in living cells provides this type of technology a potential to allow long-term imaging with least interference to protein function. Obien et al. review strategies to control microelectrodes for detecting neuronal activity and discuss techniques for higher resolution and quality of recordings using monolithic integration with on-chip circuitry. Finally, the original research article by Amariei et al. describes the oscillatory behavior of metabolites in bacteria. They describe a new method to visualize the periodic dynamics of metabolites in large scale cultures populations. These four articles contribute to the development of quantitative methods visualizing diverse targets: proteins, electrical signals and metabolites. In the second section of the topic, we have included articles on the development of computational tools to fully harness the potential of quantitative measurements through either calculation based on specific model or validation of the model itself. Kimura et al. introduce optimization procedures to search for parameters in a quantitative model that can reproduce experimental data. They present four examples: transcriptional regulation, bacterial chemotaxis, morphogenesis of tissues and organs, and cell cycle regulation. The original research article by Sumiyoshi et al. presents a general methodology to accelerate stochastic simulation efforts. They introduce a method to achieve 130 times faster computation of stochastic models by applying GPGPU. The strength of such accelerated numerical calculation are sometimes underestimated in biology; faster simulation enables multiple runs and in turn improved accuracy of numerical calculation which may change the final conclusion of modeling study. This also highlights the need to carefully assess simulation results and estimations using computational tools.
